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Proteins/UNIPROT:O14939
Function as phospholipase selective for phosphatidylcholine. May have a role in signal-induced cytoskeletal regulation and/or endocytosis (By similarity)..
Function from UniProtKB (O14939), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
74 statements
74 statements · 7 reference databases · Subject: PLD2 · Sources: Bgee, gene ontology, Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
9 reactions
water+1,2-diacyl-sn-glycero-3-phosphocholine(1+)choline+proton+phosphatidic acid
Catalysed by PLD1 or PLD2 or PLD6
Reaction pageLeft to rightBalance undeterminableEC 3.1.4.4cytosol
Human-GEM MAR00629CC BY 4.0Reference data
5 names
Resolves to: PLD2
Reaction pageLeft to rightBalance undeterminableEC 3.1.4.4cytosol
Human-GEM MAR00642CC BY 4.0Reference data
water+phosphatidyl-L-serineproton+phosphatidic acid+L-seryl residue
Reaction pageLeft to rightBalance undeterminableEC 3.1.4.4cytosol
Human-GEM MAR00660CC BY 4.0Reference data
water+1-phosphatidyl-1D-myo-inositolproton+myo-inositol+phosphatidic acid
Catalysed by PLD2
Reaction pageLeft to rightBalance undeterminableEC 3.1.4.4cytosol
Human-GEM MAR03779CC BY 4.0Reference data
water+1-(alk-1-enyl)-2-acyl-sn-glycero-3-phosphoethanolamineMAM00627c+ethanolamine+proton
Reaction pageLeft to rightBalance undeterminableEC 3.1.4.4cytosol
Human-GEM MAR07605CC BY 4.0Reference data
water+1,2-diacyl-sn-glycero-3-phosphocholine(1+)choline+proton+phosphatidic acid
Reaction pageLeft to rightBalance undeterminableEC 3.1.4.4Golgi apparatus
Human-GEM MAR08523CC BY 4.0Reference data
water+1,2-diacyl-sn-glycero-3-phosphocholine(1+)choline+proton+phosphatidic acid
Reaction pageLeft to rightBalance undeterminableEC 3.1.4.4endoplasmic reticulum
Human-GEM MAR08525CC BY 4.0Reference data
a 1,2-diacyl-sn-glycero-3-phosphocholine+watera 1,2-diacyl-sn-glycero-3-phosphate+choline+hydron
Catalysed by PLD2 or PLD1 or ENPP2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:14445CC BY 4.0Reference data
1,2-dihexadecanoyl-sn-glycero-3-phosphocholine+water1,2-dihexadecanoyl-sn-glycero-3-phosphate+choline+hydron
Reaction pageLeft to rightBalanced
Rhea RHEA:44872CC BY 4.0Reference data