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Proteins/UNIPROT:P36954
Core component of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase which synthesizes mRNA precursors and many functional non-coding RNAs using the four ribonucleoside triphosphates as substrates. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. POLR2I/RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template..
Function from UniProtKB (P36954), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
908 statements
908 statements · 3 reference databases · Subject: POLR2I · Sources: Hetionet, Reactome, WikiPathways · Rows fetched: 300
2 reactions
4 names
Resolves to: POLR2I
Reaction pageLeft to rightBalance undeterminableEC 2.7.7.6, 2.7.7.19, 2.7.7.52nucleus
Human-GEM MAR07161CC BY 4.0Reference data
phosphate(3-)+MAM02847c0.18ADP+0.3CHEBI:17239+0.34GDP+0.18UDP
Catalysed by POLRMT & POLR3A & POLR1C & POLR3G & POLR2D & POLR1A & POLR3D & POLR1D & POLR2C & POLR2E & POLR2B & POLR2I & PAPOLA & POLR2H & POLR2J & POLR2K & POLR2F & POLR2G & POLR2L & TUT7 & POLR3C & POLR1E & POLR3F & POLR1B & POLR3E & MTPAP & POLR3B & POLR1H & POLR3K & POLR3H or POLRMT & POLR3A & POLR1C & POLR3G & POLR2D & POLR1A & POLR3D & POLR1D & POLR2C & POLR2E & POLR2B & POLR2I & PAPOLA & POLR2H & POLR2J & POLR2K & POLR2F & POLR2G & POLR2L & TUT4 & POLR3C & POLR1E & POLR3F & POLR1B & POLR3E & or POLRMT & POLR3A & POLR1C & POLR3G & POLR2D & POLR1A & POLR3D & POLR1D & POLR2C & POLR2E & POLR2B & POLR2I & PAPOLA & POLR2H & POLR2J & POLR2K & POLR2F & POLR2G & POLR2L & POLR3C & POLR1E & POLR3F & TUT1 & POLR1B & POLR3E & or POLRMT & POLR3A & POLR1C & POLR3G & POLR2D & POLR1A & POLR3D & POLR1D & POLR2C & POLR2E & POLR2B & POLR2I & POLR2H & POLR2J & POLR2K & POLR2F & POLR2G & POLR2L & TUT7 & POLR3C & PAPOLG & POLR1E & POLR3F & POLR1B & POLR3E & or POLRMT & POLR3A & POLR1C & POLR3G & POLR2D & POLR1A & POLR3D & POLR1D & POLR2C & POLR2E & POLR2B & POLR2I & POLR2H & POLR2J & POLR2K & POLR2F & POLR2G & POLR2L & TUT4 & POLR3C & PAPOLG & POLR1E & POLR3F & POLR1B & POLR3E & or POLRMT & POLR3A & POLR1C & POLR3G & POLR2D & POLR1A & POLR3D & POLR1D & POLR2C & POLR2E & POLR2B & POLR2I & POLR2H & POLR2J & POLR2K & POLR2F & POLR2G & POLR2L & POLR3C & PAPOLG & POLR1E & POLR3F & TUT1 & POLR1B & POLR3E & or POLRMT & POLR3A & POLR1C & POLR3G & POLR2D & POLR1A & POLR3D & POLR1D & POLR2C & POLR2E & POLR2B & POLR2I & POLR2H & POLR2J & POLR2K & POLR2F & POLR2G & POLR2L & TUT7 & TENT2 & POLR3C & POLR1E & POLR3F & POLR1B & POLR3E & or POLRMT & POLR3A & POLR1C & POLR3G & POLR2D & POLR1A & POLR3D & POLR1D & POLR2C & POLR2E & POLR2B & POLR2I & POLR2H & POLR2J & POLR2K & POLR2F & POLR2G & POLR2L & TUT4 & TENT2 & POLR3C & POLR1E & POLR3F & POLR1B & POLR3E & or POLRMT & POLR3A & POLR1C & POLR3G & POLR2D & POLR1A & POLR3D & POLR1D & POLR2C & POLR2E & POLR2B & POLR2I & POLR2H & POLR2J & POLR2K & POLR2F & POLR2G & POLR2L & TENT2 & POLR3C & POLR1E & POLR3F & TUT1 & POLR1B & POLR3E & or POLRMT & POLR3A & POLR1C & POLR3G & POLR2D & POLR1A & POLR3D & POLR1D & POLR2C & POLR2E & POLR2B & POLR2I & POLR2H & POLR2J & POLR2K & POLR2F & POLR2G & POLR2L & TUT7 & POLR3C & POLR1E & POLR3F & POLR1B & PAPOLB & POLR3E & or POLRMT & POLR3A & POLR1C & POLR3G & POLR2D & POLR1A & POLR3D & POLR1D & POLR2C & POLR2E & POLR2B & POLR2I & POLR2H & POLR2J & POLR2K & POLR2F & POLR2G & POLR2L & TUT4 & POLR3C & POLR1E & POLR3F & POLR1B & PAPOLB & POLR3E & or POLRMT & POLR3A & POLR1C & POLR3G & POLR2D & POLR1A & POLR3D & POLR1D & POLR2C & POLR2E & POLR2B & POLR2I & POLR2H & POLR2J & POLR2K & POLR2F & POLR2G & POLR2L & POLR3C & POLR1E & POLR3F & TUT1 & POLR1B & PAPOLB & POLR3E & and 12 more alternatives
Reaction pageLeft to rightBalance undeterminableEC 2.7.7.8cytosol
Human-GEM MAR07162CC BY 4.0Reference data