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Proteins/UNIPROT:Q9BW72
Proposed subunit of cytochrome c oxidase (COX, complex IV), which is the terminal component of the mitochondrial respiratory chain that catalyzes the reduction of oxygen to water. May be involved in cytochrome c oxidase activity. May play a role in the assembly of respiratory supercomplexes..
Function from UniProtKB (Q9BW72), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
66 statements
66 statements · 5 reference databases · Subject: HIGD2A · Sources: gene ontology, Hetionet, Human-GEM, Reactome, WikiPathways
27 reactions
MAM00793c(2E)-octadecenoyl-CoA+water
Catalysed by HACD3 or HIGD2A or HACD1 or HACD4 or HACD2
Reaction pageLeft to rightBalancedEC 4.2.1.134cytosol
Human-GEM MAR02193CC BY 4.0Reference data
MAM00777c(2E)-eicosenoyl-CoA+water
2 names
Resolves to: HIGD2A
Reaction pageLeft to rightBalancedEC 4.2.1.134cytosol
Human-GEM MAR02203CC BY 4.0Reference data
MAM00776c(2E)-docosenoyl-CoA+water
Catalysed by HACD3 or HIGD2A or HACD1 or HACD4 or HACD2
Reaction pageLeft to rightBalancedEC 4.2.1.134cytosol
Human-GEM MAR02209CC BY 4.0Reference data
MAM00800c(2E)-tetracosenoyl-CoA+water
Catalysed by HACD3 or HIGD2A or HACD1 or HACD4 or HACD2
Reaction pageLeft to rightBalancedEC 4.2.1.134cytosol
Human-GEM MAR02213CC BY 4.0Reference data
MAM00783c(2E)-hexacosenoyl-CoA+water
Catalysed by HACD3 or HIGD2A or HACD1 or HACD4 or HACD2
Reaction pageLeft to rightBalancedEC 4.2.1.134cytosol
Human-GEM MAR02218CC BY 4.0Reference data
MAM00790cMAM00054c+water
Catalysed by HACD3 or HIGD2A or HACD1 or HACD4 or HACD2
Reaction pageLeft to rightBalancedEC 4.2.1.134cytosol
Human-GEM MAR02261CC BY 4.0Reference data
MAM00778cMAM00044c+water
Catalysed by HACD3 or HIGD2A or HACD1 or HACD4 or HACD2
Reaction pageLeft to rightBalancedEC 4.2.1.134cytosol
Human-GEM MAR02265CC BY 4.0Reference data
MAM00700cwater+MAM03012c
Catalysed by HACD3 or HIGD2A or HACD1 or HACD4 or HACD2
Reaction pageLeft to rightBalancedEC 4.2.1.134cytosol
Human-GEM MAR02309CC BY 4.0Reference data
MAM00701cwater+MAM03013c
Catalysed by HACD3 or HIGD2A or HACD1 or HACD4 or HACD2
Reaction pageLeft to rightBalancedEC 4.2.1.134cytosol
Human-GEM MAR02319CC BY 4.0Reference data
MAM00709cwater+MAM03015c
Catalysed by HACD3 or HIGD2A or HACD1 or HACD4 or HACD2
Reaction pageLeft to rightBalancedEC 4.2.1.134cytosol
Human-GEM MAR02328CC BY 4.0Reference data
MAM00715cwater+MAM03016c
Catalysed by HACD3 or HIGD2A or HACD1 or HACD4 or HACD2
Reaction pageLeft to rightBalancedEC 4.2.1.134cytosol
Human-GEM MAR02336CC BY 4.0Reference data
MAM00702cwater+MAM03014c
Catalysed by HACD3 or HIGD2A or HACD1 or HACD4 or HACD2
Reaction pageLeft to rightBalancedEC 4.2.1.134cytosol
Human-GEM MAR02344CC BY 4.0Reference data