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Proteins/UNIPROT:Q08397
Catalyzes the oxidative deamination of lysine and hydroxylysine residues in collagen and elastin, resulting in the formation of covalent cross-linkages, and the stabilization of collagen and elastin fibers (By similarity). Essential for the elastic fiber homeostasis and for their maintenance at adult age (By similarity)..
Function from UniProtKB (Q08397), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
279 statements
279 statements · 4 reference databases · Subject: LOXL1 · Sources: Hetionet, Reactome, UniProt, WikiPathways
1 reaction
L-lysyl-[protein]+dioxygen+water(S)-2-amino-6-oxohexanoyl-[protein]+hydrogen peroxide+ammonium
Catalysed by LOX or LOXL3 or LOXL1 or LOXL4 or LOXL2
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:24544CC BY 4.0Reference data
3 names
Resolves to: LOXL1