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Proteins/UNIPROT:Q96SZ5
Plays a vital role in regulating thiol metabolism and preserving oxygen homeostasis by oxidizing the sulfur of cysteamine and N-terminal cysteine-containing proteins to their corresponding sulfinic acids using O2 as a cosubstrate. Catalyzes the oxidation of cysteamine (2-aminoethanethiol) to hypotaurine. Catalyzes the oxidation of regulators of G protein signaling 4 (RGS4) and 5 (RGS5) and interleukin-32 (IL32)..
Function from UniProtKB (Q96SZ5), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
275 statements
275 statements · 6 reference databases · Subject: ADO · Sources: Bgee, Hetionet, Human-GEM, Reactome, Rhea, UniProt
3 reactions
cysteamine+dioxygenproton+CHEBI:16668
Catalysed by ADO
Reaction pageLeft to rightBalancedEC 1.13.11.19cytosol
Human-GEM MAR04679CC BY 4.0Reference data
cysteamine+dioxygenhypotaurine+hydron
Catalysed by ADO
Reaction pageLeft to rightBalanced
Rhea RHEA:14409CC BY 4.0Reference data
2 names
Resolves to: ADO
N-terminal L-cysteinyl-[protein]+dioxygenN-terminal S-hydroxy-S-oxy-L-cysteinyl-[protein]+hydron
Catalysed by ADO
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:70895CC BY 4.0Reference data