Proteins/UNIPROT:Q92564

DCUN1D4

ProteinUNIPROT:Q92564

Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which are necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs)..

Function from UniProtKB (Q92564), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

82 statements

82 statements · 3 reference databases · Subject: DCUN1D4 · Sources: gene ontology, Hetionet, Reactome

Order

DCUN1D4 covaries with SYT5ProteinHetionet hetionet:covaries:23142-6861Inferred only
CUL1 interacts with DCUN1D4ProteinHetionet hetionet:interacts:23142-8454Inferred only
CUL2 interacts with DCUN1D4ProteinHetionet hetionet:interacts:23142-8453Inferred only
CUL3 interacts with DCUN1D4ProteinHetionet hetionet:interacts:23142-8452Inferred only
CUL4A interacts with DCUN1D4ProteinHetionet hetionet:interacts:23142-8451Inferred only
CUL5 interacts with DCUN1D4ProteinHetionet hetionet:interacts:23142-8065Inferred only
UBE2M interacts with DCUN1D4ProteinHetionet hetionet:interacts:23142-9040Inferred only
VAV2 interacts with DCUN1D4ProteinHetionet hetionet:interacts:23142-7410Inferred only
DCUN1D4 participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
DCUN1D4 participates in NeddylationPathwayReactome R-HSA-8951664Inferred only
DCUN1D4 participates in Post-translational protein modificationPathwayReactome R-HSA-597592Inferred only
DCUN1D4 regulates positive regulation of protein neddylationBiological processgene ontology Q92564|GO:2000436Inferred only

Show the remaining 70

DCUN1D4 decreases the expression of ABCF1ProteinHetionet hetionet:regulates:23142-23Inferred only
DCUN1D4 decreases the expression of ADMProteinHetionet hetionet:regulates:23142-133Inferred only
AGL increases the expression of DCUN1D4ProteinHetionet hetionet:regulates:178-23142Inferred only
DCUN1D4 increases the expression of AGR2ProteinHetionet hetionet:regulates:23142-10551Inferred only
DCUN1D4 decreases the expression of ARNT2ProteinHetionet hetionet:regulates:23142-9915Inferred only
ATOH1 decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:474-23142Inferred only
DCUN1D4 increases the expression of B4GAT1ProteinHetionet hetionet:regulates:23142-11041Inferred only
BCKDHA decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:593-23142Inferred only
DCUN1D4 increases the expression of C2CD2ProteinHetionet hetionet:regulates:23142-25966Inferred only
DCUN1D4 decreases the expression of CDC45ProteinHetionet hetionet:regulates:23142-8318Inferred only
CISH decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:1154-23142Inferred only
COL4A5 increases the expression of DCUN1D4ProteinHetionet hetionet:regulates:1287-23142Inferred only
DCUN1D4 increases the expression of COQ8AProteinHetionet hetionet:regulates:23142-56997Inferred only
DCUN1D4 increases the expression of CPVLProteinHetionet hetionet:regulates:23142-54504Inferred only
CREB1 decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:1385-23142Inferred only
CREBBP decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:1387-23142Inferred only
DCUN1D4 increases the expression of CYTH1ProteinHetionet hetionet:regulates:23142-9267Inferred only
DCUN1D4 decreases the expression of DCTDProteinHetionet hetionet:regulates:23142-1635Inferred only
DCUN1D4 decreases the expression of DSG2ProteinHetionet hetionet:regulates:23142-1829Inferred only
ELP1 decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:8518-23142Inferred only
FADD decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:8772-23142Inferred only
FDX1 decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:2230-23142Inferred only
DCUN1D4 increases the expression of FKBP14ProteinHetionet hetionet:regulates:23142-55033Inferred only
GPR101 increases the expression of DCUN1D4ProteinHetionet hetionet:regulates:83550-23142Inferred only
H2BC12 increases the expression of DCUN1D4ProteinHetionet hetionet:regulates:85236-23142Inferred only
IFNA10 decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:3446-23142Inferred only
KHDRBS1 decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:10657-23142Inferred only
KLF11 decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:8462-23142Inferred only
LAP3 decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:51056-23142Inferred only
DCUN1D4 increases the expression of LPLProteinHetionet hetionet:regulates:23142-4023Inferred only
MBNL1 increases the expression of DCUN1D4ProteinHetionet hetionet:regulates:4154-23142Inferred only
DCUN1D4 decreases the expression of MBOAT7ProteinHetionet hetionet:regulates:23142-79143Inferred only
DCUN1D4 decreases the expression of MESTProteinHetionet hetionet:regulates:23142-4232Inferred only
MLYCD decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:23417-23142Inferred only
MPP4 increases the expression of DCUN1D4ProteinHetionet hetionet:regulates:58538-23142Inferred only
MYCBP decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:26292-23142Inferred only
NDUFB6 decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:4712-23142Inferred only
DCUN1D4 decreases the expression of NPTX2ProteinHetionet hetionet:regulates:23142-4885Inferred only
PIH1D1 increases the expression of DCUN1D4ProteinHetionet hetionet:regulates:55011-23142Inferred only
PIK3C3 decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:5289-23142Inferred only
PRLR decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:5618-23142Inferred only
PSMD3 increases the expression of DCUN1D4ProteinHetionet hetionet:regulates:5709-23142Inferred only
DCUN1D4 decreases the expression of PTPRKProteinHetionet hetionet:regulates:23142-5796Inferred only
DCUN1D4 decreases the expression of PTPROProteinHetionet hetionet:regulates:23142-5800Inferred only
DCUN1D4 decreases the expression of RAI14ProteinHetionet hetionet:regulates:23142-26064Inferred only
DCUN1D4 decreases the expression of RPIAProteinHetionet hetionet:regulates:23142-22934Inferred only
DCUN1D4 increases the expression of SCP2ProteinHetionet hetionet:regulates:23142-6342Inferred only
DCUN1D4 decreases the expression of SDC1ProteinHetionet hetionet:regulates:23142-6382Inferred only
DCUN1D4 increases the expression of SELLProteinHetionet hetionet:regulates:23142-6402Inferred only
SGCB decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:6443-23142Inferred only
DCUN1D4 increases the expression of SLC1A4ProteinHetionet hetionet:regulates:23142-6509Inferred only
SLIRP decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:81892-23142Inferred only
DCUN1D4 increases the expression of SNX6ProteinHetionet hetionet:regulates:23142-58533Inferred only
DCUN1D4 decreases the expression of SPON2ProteinHetionet hetionet:regulates:23142-10417Inferred only
DCUN1D4 decreases the expression of SPRProteinHetionet hetionet:regulates:23142-6697Inferred only
SQOR decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:58472-23142Inferred only
SSX3 decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:10214-23142Inferred only
DCUN1D4 increases the expression of ST3GAL5ProteinHetionet hetionet:regulates:23142-8869Inferred only
STAMBP decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:10617-23142Inferred only
DCUN1D4 increases the expression of STXBP1ProteinHetionet hetionet:regulates:23142-6812Inferred only
DCUN1D4 increases the expression of TATDN2ProteinHetionet hetionet:regulates:23142-9797Inferred only
TEX10 decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:54881-23142Inferred only
DCUN1D4 decreases the expression of TIMP1ProteinHetionet hetionet:regulates:23142-7076Inferred only
TMPO decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:7112-23142Inferred only
TRAF6 decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:7189-23142Inferred only
DCUN1D4 decreases the expression of TRIB3ProteinHetionet hetionet:regulates:23142-57761Inferred only
TTC3 increases the expression of DCUN1D4ProteinHetionet hetionet:regulates:7267-23142Inferred only
DCUN1D4 increases the expression of USP6NLProteinHetionet hetionet:regulates:23142-9712Inferred only
WASF3 decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:10810-23142Inferred only
ZNF680 decreases the expression of DCUN1D4ProteinHetionet hetionet:regulates:340252-23142Inferred only

Other names

4 names

Resolves to: DCUN1D4

Also called: DCNL4DCUN1 domain-containing protein 4Defective in cullin neddylation protein 1-like protein 4KIAA0276

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