Compound

CHEBI:15351

Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.

Definition from MeSH (D000105), National Library of Medicine, read 2026-09-23. NLM revises MeSH; this copy may not reflect its current record.

CHEBI:15351ChEBI

Open in the graph

What it touches on the way

Mechanistic reach

1 entity

1 entities reached.

0 reported hops1 assembled from the scaffold

SLC33A1ProteinUNIPROT:O00400transported byInferred only2 paths1 endpoint

What the reference databases state

Chemical structure

CHEBI:15351 has the functional parent acetic acidCompoundChEBI CHEBI:15351Inferred only
phenylacetyl-CoA has the functional parent CHEBI:15351CompoundChEBI CHEBI:15537Inferred only

Statements

2 statements

2 statements · 1 reference database · Subject: CHEBI:15351 · Sources: Human-GEM

Order

CHEBI:15351 is transported by SLC33A1ProteinHuman-GEM MAR00057Inferred only
CHEBI:15351 is transported by SLC33A1ProteinHuman-GEM MAR08225Inferred only

Reactions

324 reactions

MAM00982m+CHEBI:1146900+water+NAD(+)MAM00996m+CHEBI:15351+proton+NADH(2-)
Reaction pageLeft to rightBalancedmitochondrial matrix
Human-GEM MAR00047CC BY 4.0Reference data
CHEBI:15351CHEBI:15351
Transported by SLC33A1
Reaction pageReversibleBalancedcytosol, endoplasmic reticulum
Human-GEM MAR00057CC BY 4.0Reference data
CHEBI:15351+cholineacetylcholine+CHEBI:1146900
Catalysed by CHAT
Reaction pageLeft to rightBalancedEC 2.3.1.6cytosol
Human-GEM MAR00640CC BY 4.0Reference data
CHEBI:1146900+water+NAD(+)+4,8-dimethylnonanoyl-CoACHEBI:15351+3proton+NADH(2-)+MAM03553m
Catalysed by ACADM
Reaction pageLeft to rightUnbalancedEC 1.3.8.7mitochondrial matrix
Human-GEM MAR00751CC BY 4.0Reference data
6CHEBI:1146900+6FAD+6water+tetradecanoyl-CoA+6NAD(+)7CHEBI:15351+6FADH2+6proton+6NADH(2-)
Catalysed by ACADM or ACADS
Reaction pageLeft to rightBalancedEC 1.3.8.7mitochondrial matrix
Human-GEM MAR00752CC BY 4.0Reference data
6CHEBI:1146900+6FAD+6water+6NAD(+)+MAM02689m6CHEBI:15351+6FADH2+6proton+6NADH(2-)+propionyl-CoA
Catalysed by ACADM or ACADS
Reaction pageLeft to rightBalancedEC 1.3.8.7mitochondrial matrix
Human-GEM MAR00755CC BY 4.0Reference data
7CHEBI:1146900+7FAD+7water+7NAD(+)+palmitoyl-CoA8CHEBI:15351+7FADH2+7proton+7NADH(2-)
Catalysed by ACADM or ACADS
Reaction pageLeft to rightBalancedEC 1.3.8.7mitochondrial matrix
Human-GEM MAR00756CC BY 4.0Reference data
4CHEBI:1146900+4FAD+4water+4NAD(+)+palmitoyl-CoA4CHEBI:15351+4FADH2+4proton+4NADH(2-)+octanoyl-CoA
Catalysed by ACADM or ACADS
Reaction pageLeft to rightBalancedEC 4.2.1.74mitochondrial matrix
Human-GEM MAR00757CC BY 4.0Reference data
4CHEBI:1146900+4FAD+4water+4NAD(+)+palmitoyl-CoA4CHEBI:15351+4FADH2+4proton+4NADH(2-)+octanoyl-CoA
Catalysed by ACAA1 & HSD17B4 & ACOX1 or ACAA1 & EHHADH & ACOX1
Reaction pageLeft to rightBalancedEC 4.2.1.74peroxisome
Human-GEM MAR00759CC BY 4.0Reference data
(2E)-hexadecenoyl-CoA+4CHEBI:1146900+3FAD+4water+4NAD(+)4CHEBI:15351+3FADH2+4proton+4NADH(2-)+octanoyl-CoA
Catalysed by ACADM or ACADS
Reaction pageLeft to rightBalancedEC 4.2.1.74mitochondrial matrix
Human-GEM MAR00764CC BY 4.0Reference data
4CHEBI:1146900+3FAD+4water+4NAD(+)+(9Z)-hexadecenoyl-CoA4CHEBI:15351+3FADH2+4proton+4NADH(2-)+octanoyl-CoA
Catalysed by ACADM or ACADS
Reaction pageLeft to rightBalancedEC 4.2.1.74mitochondrial matrix
Human-GEM MAR00772CC BY 4.0Reference data
7CHEBI:1146900+7FAD+7water+heptadecanoyl-CoA+7NAD(+)7CHEBI:15351+7FADH2+7proton+7NADH(2-)+propionyl-CoA
Catalysed by ACADM
Reaction pageLeft to rightBalancedEC 1.3.8.7mitochondrial matrix
Human-GEM MAR00774CC BY 4.0Reference data

Show the remaining 312

Other names

6 names

Resolves to: CHEBI:15351

Also called: AcCoAAcetyl coenzyme AAcetyl-CoAS-acetyl-CoAS-acetyl-coenzyme A
Systematic name: 3'-phosphoadenosine 5'-(3-{(3R)-4-[(3-{[2-(acetylsulfanyl)ethyl]amino}-3-oxopropyl)amino]-3-hydroxy-2,2-dimethyl-4-oxobutyl} dihydrogen diphosphate)