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Proteins/UNIPROT:Q15125
Isomerase that catalyzes the conversion of Delta(8)-sterols to their corresponding Delta(7)-isomers a catalytic step in the postlanosterol biosynthesis of cholesterol..
Component of the microsomal antiestrogen binding site (AEBS), a multiproteic complex at the ER membrane that consists of an association between EBP and 7-dehydrocholesterol reductase/DHCR7. This complex is responsible for cholesterol-5,6-epoxide hydrolase (ChEH) activity, which consists in the hydration of cholesterol-5,6-epoxides (5,6-EC) into cholestane-3beta,5alpha,6beta-triol (CT). The precise role of each component of this complex has not been described yet..
Function from UniProtKB (Q15125), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
412 statements
412 statements · 5 reference databases · Subject: EBP · Sources: Hetionet, Human-GEM, Reactome, Rhea, WikiPathways · Rows fetched: 300
8 reactions
MAM03158rMAM01066r
Catalysed by EBP
Reaction pageLeft to rightBalancedEC 5.3.3.5endoplasmic reticulum
Human-GEM MAR00443CC BY 4.0Reference data
MAM03158cMAM01066c
Catalysed by EBP
Reaction pageLeft to rightBalancedEC 5.3.3.5cytosol
Human-GEM MAR01512CC BY 4.0Reference data
MAM01449clathosterol
Catalysed by EBP
Reaction pageLeft to right
7 names
Resolves to: EBP
Human-GEM MAR01553CC BY 4.0Reference data
lathosterolMAM01449r
Catalysed by EBP
Reaction pageReversibleBalancedEC 5.3.3.5endoplasmic reticulum
Human-GEM MAR02339CC BY 4.0Reference data
CHEBI:49305+waterCHEBI:28082
Reaction pageLeft to rightBalanced
Rhea RHEA:11964CC BY 4.0Reference data
CHEBI:28164+waterCHEBI:28082
Reaction pageLeft to rightBalanced
Rhea RHEA:15113CC BY 4.0Reference data
lathosterolCHEBI:16608
Catalysed by EBP
Reaction pageLeft to rightBalanced
Rhea RHEA:15281CC BY 4.0Reference data
CHEBI:18252CHEBI:16290
Catalysed by EBP
Reaction pageLeft to rightBalanced
Rhea RHEA:33999CC BY 4.0Reference data