What it touches on the way
Mechanistic reach
5 entities
5 entities reached.
0 reported hops5 assembled from the scaffold
- HADHAProteinUNIPROT:P40939substrate ofInferred only37 paths37 endpoints
- HADHBProteinUNIPROT:P55084substrate ofInferred only33 paths32 endpoints
- HSD17B4ProteinUNIPROT:P51659substrate ofInferred only27 paths27 endpoints
- ACAA1ProteinUNIPROT:P09110substrate ofInferred only24 paths24 endpoints
- EHHADHProteinUNIPROT:Q08426substrate ofInferred only21 paths21 endpoints
What the reference databases state
Statements
5 statements
5 statements · 1 reference database · Subject: (2E,6Z,9Z,12Z)-octadecatetraenoyl-CoA · Sources: Human-GEM
- (2E,6Z,9Z,12Z)-octadecatetraenoyl-CoA is a substrate of ACAA1ProteinHuman-GEM MAR05364Inferred only
- (2E,6Z,9Z,12Z)-octadecatetraenoyl-CoA is a substrate of EHHADHProteinHuman-GEM MAR05364Inferred only
- (2E,6Z,9Z,12Z)-octadecatetraenoyl-CoA is a substrate of HADHAProteinHuman-GEM MAR05360Inferred only
- (2E,6Z,9Z,12Z)-octadecatetraenoyl-CoA is a substrate of HADHBProteinHuman-GEM MAR05360Inferred only
- (2E,6Z,9Z,12Z)-octadecatetraenoyl-CoA is a substrate of HSD17B4ProteinHuman-GEM MAR05364Inferred only
Reactions
8 reactions
CHEBI:1146900+water+NAD(+)+(2E,6Z,9Z,12Z)-octadecatetraenoyl-CoAMAM00091m+CHEBI:15351+proton+NADH(2-)
Reaction pageLeft to rightBalancedGO:0005759
Human-GEM MAR05360CC BY 4.0Reference data
CHEBI:1146900+water+NAD(+)+(2E,6Z,9Z,12Z)-octadecatetraenoyl-CoACHEBI:15351+proton+NADH(2-)+MAM03274x
Catalysed by ACAA1 & HSD17B4 & EHHADH
Reaction pageLeft to rightBalancedGO:0005777
Human-GEM MAR05364CC BY 4.0Reference data
MAM03254m(2E,6Z,9Z,12Z)-octadecatetraenoyl-CoA
Catalysed by ECI1
Reaction pageLeft to rightBalancedEC 5.3.3.8GO:0005759
Human-GEM MAR05367CC BY 4.0Reference data
MAM03254x(2E,6Z,9Z,12Z)-octadecatetraenoyl-CoA
Reaction pageLeft to rightBalancedGO:0005777
Human-GEM MAR05368CC BY 4.0Reference data
(6Z,9Z,12Z)-octadecatrienoyl-CoA+oxidized [electron-transfer flavoprotein]+hydron(2E,6Z,9Z,12Z)-octadecatetraenoyl-CoA+reduced [electron-transfer flavoprotein]
Catalysed by ACADL or ACADVL or ACAD9
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:84619CC BY 4.0Reference data
(2E,6Z,9Z,12Z)-octadecatetraenoyl-CoA+waterCHEBI:233839
Catalysed by HADHA
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:84667CC BY 4.0Reference data
(6Z,9Z,12Z)-octadecatrienoyl-CoA+dioxygen(2E,6Z,9Z,12Z)-octadecatetraenoyl-CoA+hydrogen peroxide
Catalysed by ACOX1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:84907CC BY 4.0Reference data
(2E,6Z,9Z,12Z)-octadecatetraenoyl-CoA+waterCHEBI:233779
Catalysed by HSD17B4
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:84915CC BY 4.0Reference data