4-aminobutanoate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

307 compounds within 3 steps: 6 in 1, 51 in 2, 250 in 3

One step

L-homocarnosineReach from here →
1. Formation of homocarnosine
Catalysed by CARNS1cytosolOne of 2 routes
succinic semialdehydeReach from here →
1. 4-aminobutanoate:2-oxoglutarate aminotransferase
Catalysed by ABATmitochondrial matrix
chlorine(.)Reach from here →
1. transport of 4-aminobutyrate and chloride (cytosol to extracellular)
Catalysed by SLC6A12extracellular space, cytosolOne of 4 routes
L-ornithineReach from here →
1. 4-aminobutanoate + L-arginine = 4-guanidinobutanoate + L-ornithine
Catalysed by GATM
4-guanidinobutanoateReach from here →
1. 4-aminobutanoate + L-arginine = 4-guanidinobutanoate + L-ornithine
Catalysed by GATM
succinate semialdehydeReach from here →
1. 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate
Catalysed by ABAT

Two steps

(S)-carnitineReach from here →
1. transport of 4-aminobutyrate and chloride (cytosol to extracellular)
2. Carnitine Transport by Atb0
Catalysed by SLC6A12, SLC6A14extracellular space, cytosol
D-histidineReach from here →
1. 4-aminobutanoate + L-arginine = 4-guanidinobutanoate + L-ornithine
2. D-histidine(in) + L-ornithine(out) + H(+)(in) = D-histidine(out) + L-ornithine(in) + H(+)(out)
Catalysed by GATM, SLC25A2inner side of the membrane, outer side of the membraneOne of 2 routes
L-homoarginineReach from here →

Catalysed by GATM, SLC25A2inner side of the membrane, outer side of the membraneOne of 2 routes

cholineReach from here →

Catalysed by SLC6A12, SLC5A7extracellular space, cytosol

L-leucineReach from here →

Catalysed by SLC6A12, SLC6A14extracellular space, cytosolOne of 6 routes

CHEBI:15699Reach from here →

Catalysed by GATM, SLC7A6extracellular space, cytosolOne of 2 routes

CHEBI:15971Reach from here →

Catalysed by CARNS1, CNDP1, CNDP2cytosolOne of 6 routes

sulfateReach from here →

Catalysed by SLC6A12, SLC26A6extracellular space, cytosol

ureaReach from here →

Catalysed by GATM, AGMAT

L-citrullineReach from here →

Catalysed by GATM, SLC7A9extracellular space, cytosolOne of 9 routes

iodideReach from here →

Catalysed by SLC6A12, SLC26A4extracellular space, cytosol

L-valineReach from here →

Catalysed by SLC6A12, SLC6A14extracellular space, cytosolOne of 4 routes

L-arginineReach from here →

Catalysed by SLC6A12, SLC6A14extracellular space, cytosolOne of 9 routes

N(2)-acetyl-L-ornithineReach from here →

Catalysed by GATM, ACY1cytosol

4-hydroxybutanoateReach from here →

Catalysed by ABATmitochondrial matrixOne of 3 routes

CHEBI:16857Reach from here →

Catalysed by SLC6A12, SLC6A14extracellular space, cytosolOne of 3 routes

oxalic acidReach from here →

Catalysed by SLC6A12, SLC26A6extracellular space, cytosol

L-isoleucineReach from here →

Catalysed by SLC6A12, SLC6A14extracellular space, cytosolOne of 4 routes

CHEBI:17203Reach from here →

Catalysed by SLC6A12, CLTRN, SLC6A20extracellular space, cytosolOne of 4 routes

L-glutamic 5-semialdehydeReach from here →

Catalysed by GATM, OATmitochondrial matrix

L-cysteineReach from here →

Catalysed by SLC6A12, SLC6A14extracellular space, cytosolOne of 4 routes

glycine betaineReach from here →

Catalysed by SLC6A12extracellular space, cytosolOne of 3 routes

CHEBI:17895Reach from here →

Catalysed by SLC6A12, SLC6A14extracellular space, cytosolOne of 4 routes

CHEBI:18019Reach from here →

Catalysed by SLC6A12, SLC6A14extracellular space, cytosolOne of 5 routes

L-glutamineReach from here →

Catalysed by SLC6A12, SLC6A14extracellular space, cytosolOne of 3 routes

CHEBI:18095Reach from here →

Catalysed by SLC6A12, CLTRN, SLC6A20extracellular space, cytosol

N-carbamoyl-beta-alanineReach from here →

Catalysed by SLC6A12extracellular space, cytosolOne of 2 routes

CHEBI:240943Reach from here →

Catalysed by SLC6A12, SLC6A5extracellular space, cytosolOne of 2 routes

hypochlorous acidReach from here →

Catalysed by SLC6A12, LPOextracellular space, cytosolOne of 4 routes

potassium atomReach from here →

Catalysed by SLC6A12, SLC12A2, SLC12A1extracellular space, cytosolOne of 2 routes

Ca(2+)Reach from here →

Catalysed by CARNS1cytosol, extracellular spaceOne of 2 routes

formic acidReach from here →

Catalysed by SLC6A12, SLC26A4extracellular space, cytosolOne of 2 routes

malonic acidReach from here →

Catalysed by SLC6A12extracellular space, cytosolOne of 2 routes

L-lysineReach from here →

Catalysed by GATM, SLC25A2, SLC25A15inner side of the membrane, outer side of the membraneOne of 2 routes

D-lysineReach from here →

Catalysed by GATM, SLC25A2inner side of the membrane, outer side of the membraneOne of 2 routes

putrescineReach from here →

Catalysed by GATM, ODC1cytosolOne of 3 routes

D-arginineReach from here →

Catalysed by GATM, SLC25A2inner side of the membrane, outer side of the membraneOne of 2 routes

taurineReach from here →

Catalysed by SLC6A12, SLC6A6extracellular space, cytosolOne of 2 routes

glycineReach from here →

Catalysed by SLC6A12, SLC6A9, SLC6A14extracellular space, cytosolOne of 7 routes

L-histidineReach from here →

Catalysed by CARNS1, CNDP1cytosolOne of 3 routes

D-ornithineReach from here →

Catalysed by GATM, SLC25A2inner side of the membrane, outer side of the membraneOne of 2 routes

guanidinoacetateReach from here →

Catalysed by SLC6A12extracellular space, cytosol

L-methionineReach from here →

Catalysed by SLC6A12, SLC6A14extracellular space, cytosolOne of 4 routes

L-tryptophanReach from here →

Catalysed by SLC6A12, SLC6A14extracellular space, cytosolOne of 4 routes