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Proteins/UNIPROT:Q9NP91
Mediates the Na(+)- and Cl(-)-dependent uptake of imino acids such as L-proline, N-methyl-L-proline and pipecolate as well as N-methylated amino acids. Also transports glycine, regulates proline and glycine homeostasis in the brain playing a role in the modulation of NMDAR currents..
Function from UniProtKB (Q9NP91), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 1 · transported by
1 compound
1 compound.
0 reported routes1 assembled route
52 statements
52 statements · 6 reference databases · Subject: SLC6A20 · Sources: Bgee, Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
10 reactions
sodium(1+)+CHEBI:17203sodium(1+)+CHEBI:17203
Transported by SLC6A7 or SLC6A15 or SLC38A1 or SLC38A2 or SLC38A4 or SLC6A20
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR05322CC BY 4.0Reference data
6 names
Resolves to: SLC6A20
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR06860CC BY 4.0Reference data
chlorine(.)+2sodium(1+)+CHEBI:17203chlorine(.)+2sodium(1+)+CHEBI:17203
Transported by CLTRN & SLC6A20
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR07194CC BY 4.0Reference data
glycine+chloride+2sodium(1+)glycine+chloride+2sodium(1+)
Transported by SLC6A9 or SLC6A20 or SLC6A14
Reaction pageDirection not assertedBalanced
Rhea RHEA:70691CC BY 4.0Reference data
glycine betaine+chloride+2sodium(1+)glycine betaine+chloride+2sodium(1+)
Transported by SLC6A20
Reaction pageDirection not assertedBalanced
Rhea RHEA:70735CC BY 4.0Reference data
L-proline+chloride+2sodium(1+)L-proline+chloride+2sodium(1+)
Transported by SLC6A7 or SLC6A20
Reaction pageDirection not assertedBalanced
Rhea RHEA:71263CC BY 4.0Reference data
L-pipecolate+chloride+2sodium(1+)L-pipecolate+chloride+2sodium(1+)
Transported by SLC6A7 or SLC6A20
Reaction pageDirection not assertedBalanced
Rhea RHEA:71267CC BY 4.0Reference data
sarcosine+chloride+2sodium(1+)sarcosine+chloride+2sodium(1+)
Transported by SLC6A20
Reaction pageDirection not assertedBalanced
Rhea RHEA:72227CC BY 4.0Reference data
N-methyl-L-proline+chloride+2sodium(1+)N-methyl-L-proline+chloride+2sodium(1+)
Transported by SLC6A20
Reaction pageDirection not assertedBalanced
Rhea RHEA:72231CC BY 4.0Reference data
2-methyl-2-(methylamino)propanoate+chloride+2sodium(1+)2-methyl-2-(methylamino)propanoate+chloride+2sodium(1+)
Transported by SLC6A20
Reaction pageDirection not assertedBalanced
Rhea RHEA:72235CC BY 4.0Reference data