4-hydroxybutanoate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

64 compounds within 3 steps: 2 in 1, 2 in 2, 60 in 3

One step

(R)-2-hydroxyglutarateReach from here →
1. 4-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + succinate semialdehyde
Catalysed by ADHFE1
succinate semialdehydeReach from here →
1. 4-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + succinate semialdehyde
Catalysed by ADHFE1One of 2 routes

Two steps

(S)-3-hydroxybutanoateReach from here →
1. 4-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + succinate semialdehyde
2. (S)-3-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + acetoacetate
Catalysed by ADHFE1
AH2Reach from here →
1. 4-hydroxybutanoate + 2-oxoglutarate = (R)-2-hydroxyglutarate + succinate semialdehyde
2. (R)-2-hydroxyglutarate + A = 2-oxoglutarate + AH2
Catalysed by ADHFE1, D2HGDH

Three steps

ADHFE1

, D2HGDH

, AIFM1

, PYROXD1

One of 70 routes

(18S)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoateReach from here →

Catalysed by ADHFE1, D2HGDH, PTGS2

(15S)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoateReach from here →

Catalysed by ADHFE1, D2HGDH, PTGS2

prostaglandin H3Reach from here →

Catalysed by ADHFE1, D2HGDH, PTGS2

13-hydroxy-(9Z,11E)-octadecadienoateReach from here →

Catalysed by ADHFE1, D2HGDH, PTGS2

9-hydroxy-(10E,12Z)-octadecadienoateReach from here →

Catalysed by ADHFE1, D2HGDH, PTGS2

(13R)-hydroxy-(9Z,11E)-octadecadienoateReach from here →

Catalysed by ADHFE1, D2HGDH, PTGS1, PTGS2

acetoacetateReach from here →

Catalysed by ADHFE1mitochondrial matrixOne of 2 routes

2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphocholineReach from here →

Catalysed by ADHFE1, D2HGDH, PTGS2

2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholineReach from here →

Catalysed by ADHFE1, D2HGDH, PTGS2

2-[(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholineReach from here →

Catalysed by ADHFE1, D2HGDH, PTGS2

2-(prostaglandin H2)-sn-glycero-3-phosphoethanolamineReach from here →

Catalysed by ADHFE1, D2HGDH, PTGS2

2-(prostaglandin H2)-sn-glycero-3-phosphocholineReach from here →

Catalysed by ADHFE1, D2HGDH, PTGS2

cob(II)alaminReach from here →

Catalysed by ADHFE1, D2HGDH, MTRR

iodideReach from here →

Catalysed by ADHFE1, D2HGDH, DIO1, DIO3One of 22 routes

nitric oxideReach from here →

Catalysed by ADHFE1, D2HGDH, SUOX

3'-deoxy-3',4'-didehydro-CTPReach from here →

Catalysed by ADHFE1, D2HGDH, RSAD2

(S)-2-hydroxyglutarateReach from here →

Catalysed by ADHFE1, D2HGDH, L2HGDH

5'-deoxyadenosineReach from here →

Catalysed by ADHFE1, D2HGDH, CDK5RAP1One of 4 routes

3,3',5'-triiodo-L-thyronine sulfateReach from here →

Catalysed by ADHFE1, D2HGDH, DIO1

3,3'-diiodo-L-thyronineReach from here →

Catalysed by ADHFE1, D2HGDH, DIO1, DIO3One of 2 routes

3,3'-diiodo-L-thyronine sulfateReach from here →

Catalysed by ADHFE1, D2HGDH, DIO1One of 2 routes

3',5'-diiodo-L-thyronineReach from here →

Catalysed by ADHFE1, D2HGDH, DIO3

3-iodothyronamineReach from here →

Catalysed by ADHFE1, D2HGDH, DIO1, DIO3One of 2 routes

3-iodo-L-thyronineReach from here →

Catalysed by ADHFE1, D2HGDH, DIO1, DIO3One of 2 routes

3'-iodo-L-thyronineReach from here →

Catalysed by ADHFE1, D2HGDH, DIO1, DIO2One of 2 routes

L-thyronineReach from here →

Catalysed by ADHFE1, D2HGDH, DIO3

thyronamineReach from here →

Catalysed by ADHFE1, D2HGDH, DIO3

3'-iodothyronamineReach from here →

Catalysed by ADHFE1, D2HGDH, DIO1, DIO2One of 2 routes

3,3'-diiodothyronamineReach from here →

Catalysed by ADHFE1, D2HGDH, DIO1, DIO2One of 2 routes

3',5'-diiodothyronamineReach from here →

Catalysed by ADHFE1, D2HGDH, DIO3

3,3',5'-triiodothyronamineReach from here →

Catalysed by ADHFE1, D2HGDH, DIO3

hydrogenselenideReach from here →

Catalysed by ADHFE1, D2HGDH, SCLY

25-hydroxycholesterolReach from here →

Catalysed by ADHFE1, D2HGDH, CH25H

all-trans-13,14-dihydroretinolReach from here →

Catalysed by ADHFE1, D2HGDH, RETSAT

3,3',5-triiodo-L-thyronineReach from here →

Catalysed by ADHFE1, D2HGDH, DIO1, DIO2

3,3',5'-triiodo-L-thyronineReach from here →

Catalysed by ADHFE1, D2HGDH, DIO1, DIO3

prostaglandin H2Reach from here →

Catalysed by ADHFE1, D2HGDH, PTGS1, PTGS2One of 2 routes

(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoateReach from here →

Catalysed by ADHFE1, D2HGDH, TBXAS1, PTGS2 and 1 more

L-methionineReach from here →

Catalysed by ADHFE1, D2HGDH, CDK5RAP1One of 4 routes

L-alanineReach from here →

Catalysed by ADHFE1, D2HGDH, SCLYOne of 2 routes

a 2,3-saturated acyl-CoAReach from here →

Catalysed by ADHFE1, D2HGDH, ACAD10

(9S)-hydroxy-(10E,12Z)-octadecadienoateReach from here →

Catalysed by ADHFE1, D2HGDH, PTGS1, PTGS2

(9R)-hydroxy-(10E,12Z)-octadecadienoateReach from here →

Catalysed by ADHFE1, D2HGDH, PTGS1, PTGS2

(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoateReach from here →

Catalysed by ADHFE1, D2HGDH, PTGS2