trans-urocanate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

74 compounds within 3 steps: 1 in 1, 6 in 2, 67 in 3

One step

L-histidineReach from here →
1. L-histidine = trans-urocanate + NH4(+)
Catalysed by HAL

Two steps

L-homocarnosineReach from here →
1. L-histidine = trans-urocanate + NH4(+)
2. 4-aminobutanoate + L-histidine + ATP = L-homocarnosine + ADP + phosphate + H(+)
Catalysed by HAL, CARNS1
L-arginineReach from here →
1. L-histidine = trans-urocanate + NH4(+)
2. L-histidine(out) + L-arginine(in) + Na(+)(out) = L-histidine(in) + L-arginine(out) + Na(+)(in)
Catalysed by HAL, SLC7A6inner side of the membrane, outer side of the membraneOne of 3 routes
L-ornithineReach from here →
1. L-histidine = trans-urocanate + NH4(+)
2. L-histidine(in) + L-ornithine(out) + H(+)(in) = L-histidine(out) + L-ornithine(in) + H(+)(out)
Catalysed by HAL, SLC25A2inner side of the membrane, outer side of the membraneOne of 2 routes
carnosineReach from here →
1. L-histidine = trans-urocanate + NH4(+)
2. beta-alanine + L-histidine + ATP = carnosine + ADP + phosphate + H(+)
Catalysed by HAL, CARNS1
L-phenylalanineReach from here →
1. L-histidine = trans-urocanate + NH4(+)
2. L-histidine(in) + L-phenylalanine(out) = L-histidine(out) + L-phenylalanine(in)
Catalysed by HAL, SLC7A8inner side of the membrane, outer side of the membraneOne of 2 routes
histamineReach from here →
1. L-histidine = trans-urocanate + NH4(+)
2. L-histidine + H(+) = histamine + CO2
Catalysed by HAL, HDC

Three steps

N(omega)-methyl-L-arginineReach from here →
Catalysed by HAL, SLC7A6, SLC25A29inner side of the membrane, outer side of the membraneOne of 2 routes
2,4-dinitrophenyl-S-glutathioneReach from here →

Catalysed by HAL, HDC, SLCO1A2, SLCO1B3

extracellular space, cytosol

One of 2 routes

N-(9Z-octadecenoyl)-L-phenylalanineReach from here →

Catalysed by HAL, SLC7A8, PM20D1inner side of the membrane, outer side of the membrane

N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-phenylalanineReach from here →

Catalysed by HAL, SLC7A8, PM20D1inner side of the membrane, outer side of the membrane

D-histidineReach from here →

Catalysed by HAL, SLC25A2inner side of the membrane, outer side of the membraneOne of 2 routes

L-homoarginineReach from here →

Catalysed by HAL, SLC25A2inner side of the membrane, outer side of the membraneOne of 4 routes

kinetensinReach from here →

Catalysed by HAL, SLC7A8, CMA1inner side of the membrane, outer side of the membrane, extracellular space

4a-hydroxytetrahydrobiopterinReach from here →

Catalysed by HAL, SLC7A8, PAHinner side of the membrane, outer side of the membrane, cytosol

L-leucineReach from here →

Catalysed by HAL, SLC25A2, SLC7A6inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 16 routes

(4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterinReach from here →

Catalysed by HAL, SLC7A8, PAHinner side of the membrane, outer side of the membrane

CHEBI:15699Reach from here →

Catalysed by HAL, SLC25A2, SLC7A6inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 7 routes

CHEBI:15971Reach from here →

Catalysed by HAL, CARNS1, CNDP1, CNDP2cytosolOne of 13 routes

ureaReach from here →

Catalysed by HAL, SLC7A6, ARG1inner side of the membrane, outer side of the membrane, cytosolOne of 3 routes

L-cystineReach from here →

Catalysed by HAL, SLC7A6, SLC7A9inner side of the membrane, outer side of the membrane

L-citrullineReach from here →

Catalysed by HAL, SLC25A2, SLC7A9inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 18 routes

L-valineReach from here →

Catalysed by HAL, SLC25A2, SLC7A6inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 9 routes

nitric oxideReach from here →

Catalysed by HAL, SLC7A6, NOS3, NOS1 and 1 moreinner side of the membrane, outer side of the membrane, cytosolOne of 2 routes

protein polypeptide chainReach from here →

Catalysed by HAL, SLC7A6inner side of the membrane, outer side of the membrane, cytosolOne of 2 routes

N(2)-acetyl-L-ornithineReach from here →

Catalysed by HAL, SLC25A2, ACY1inner side of the membrane, outer side of the membrane, cytosol

2-phenylacetamideReach from here →

Catalysed by HAL, SLC7A8, EPXinner side of the membrane, outer side of the membrane, cytosol

N-[(S)-lactoyl]-L-phenylalanineReach from here →

Catalysed by HAL, SLC7A8, CNDP2inner side of the membrane, outer side of the membrane

CHEBI:16856Reach from here →

Catalysed by HAL, HDC, SLCO1A2, SLCO1B3extracellular space, cytosolOne of 2 routes

CHEBI:16857Reach from here →

Catalysed by HAL, SLC25A2, SLC7A6inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 8 routes

L-isoleucineReach from here →

Catalysed by HAL, SLC25A2, SLC7A6inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 9 routes

CHEBI:17203Reach from here →

Catalysed by HAL, SLC25A2, SLC7A6inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 7 routes

L-glutamic 5-semialdehydeReach from here →

Catalysed by HAL, SLC25A2, OATinner side of the membrane, outer side of the membrane, mitochondrial matrix

agmatineReach from here →

Catalysed by HAL, SLC7A6inner side of the membrane, outer side of the membrane, mitochondrial matrix

L-cysteineReach from here →

Catalysed by HAL, SLC25A2, SLC7A6inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 13 routes

CHEBI:17895Reach from here →

Catalysed by HAL, SLC25A2, SLC7A6inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 9 routes

CHEBI:17927Reach from here →

Catalysed by HAL, SLC7A6, SLC3A2inner side of the membrane, outer side of the membrane, extracellular space, cytosol

3-phenylpyruvateReach from here →

Catalysed by HAL, SLC7A8, GOT2, TATinner side of the membrane, outer side of the membrane, mitochondrial matrixOne of 5 routes

CHEBI:18019Reach from here →

Catalysed by HAL, SLC25A2, SLC7A5, SLC7A6inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 10 routes

L-glutamineReach from here →

Catalysed by HAL, SLC25A2, SLC7A6inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 14 routes

2-phenylethylamineReach from here →

Catalysed by HAL, SLC7A8, DDCinner side of the membrane, outer side of the membrane, cytosol

S-methylmercury-L-cysteineReach from here →

Catalysed by HAL, SLC7A8inner side of the membrane, outer side of the membraneOne of 2 routes

imidazole-4-acetaldehydeReach from here →

Catalysed by HAL, HDC, AOC2, AOC1 and 1 morecytosolOne of 2 routes

Ca(2+)Reach from here →

Catalysed by HAL, CARNS1extracellular space, cytosolOne of 2 routes

Phe-tRNA(Phe)Reach from here →

Catalysed by HAL, SLC7A8, FARSB, FARSAinner side of the membrane, outer side of the membrane, cytosol

chlorine(.)Reach from here →

Catalysed by HAL, SLC7A6, SLC6A14inner side of the membrane, outer side of the membrane, extracellular space, cytosolOne of 4 routes

L-aspartateReach from here →

Catalysed by HAL, SLC7A8, SLC7A13inner side of the membrane, outer side of the membraneOne of 2 routes

L-lysineReach from here →

Catalysed by HAL, SLC25A2, SLC25A15inner side of the membrane, outer side of the membraneOne of 3 routes

D-lysineReach from here →

Catalysed by HAL, SLC25A2inner side of the membrane, outer side of the membraneOne of 2 routes

putrescineReach from here →

Catalysed by HAL, SLC25A2, ODC1inner side of the membrane, outer side of the membrane, cytosolOne of 4 routes