Compound
all-cis-docosa-4,7,10,13,16,19-hexaenoic acid
C22-unsaturated fatty acids found predominantly in fish oils.
Studied for
10 endpoints · 7 findings · 9 papers · 1 null
- Adverse event occurrence (oral or enteral supplement)no detected effectEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.
- Necrotising enterocolitis incidencelowersEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.
- Birth weightraisesEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.
- TriglycerideslowersEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.
- Tumour necrosis factor alpha concentrationraisesEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.
Structure
A docosahexaenoic acid having six cis-double bonds at positions 4, 7, 10, 13, 16 and 19.
Loading the model…
- Class
- Organic compound
- Formula
- C22H32O2
- Mass
- 328.496 g/mol
- Charge
- 0
- InChIKey
- MBMBGCFOFBJSGT-KUBAVDMBSA-N
- SMILES
- CC/C=CC/C=CC/C=CC/C=CC/C=CC/C=CCCC(=O)O
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What the evidence says
How to read these marks10 findings · 10 endpoints · 9 papers · 1 null · by evidence strength
What moved
9 findings
Decreases necrotising enterocolitis incidence
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“Confirmed NEC was lower in infants from the DHA-group compared with the control-group (0/100 vs. 7/100, p = 0.007) with a RR of 0.93 (95% CI 0.881 to 0.981, p = 0.008); there was a risk difference of −7% (95% CI −12.00 to −1.99), and a number needed to treat of 15 (95% CI 8.3 to 50).”
Quoted verbatim from Efficacy of Docosahexaenoic Acid for the Prevention of Necrotizing Enterocolitis in Preterm Infants: A Randomized Clinical Trial.. - Study
- RCT
- Duration
- 14 days
- Dose
- 75 mg DHA/kg body weight daily for 14 days from the first enteral feed
- Population
- Preterm infants (birthweight 1000-1500 g) dosed enterally by orogastric tube; outcome measured in the same infants; per-protocol analysis; confirmed NEC defined as Bell stage IIa or greater (modified Walsh)
Effect 0.93 risk ratio, 95% CI 0.881 to 0.981
Efficacy of Docosahexaenoic Acid for the Prevention of Necrotizing Enterocolitis in Preterm Infants: A Randomized Clinical Trial.2021PMID:33671220An author is affiliated with a producerPermalink
Increases birth weight
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“In contrast, prenatal DHA supplementation significantly increased neonatal birth weight (mean difference [MD] = 72.51 g, 95% CI: 37.55-107.48), whereas no notable improvements were observed in head circumference, gestational age, birth length, or any of the assessed neurodevelopmental outcomes.”
Quoted verbatim from Impact of Omega-3 Fatty Acid Docosahexaenoic Acid Supplementation in Individuals During Pregnancy on Neurodevelopment and Growth of Offspring: Systematic Review and Meta-Analysis.. - Study
- meta-analysis
- Population
- Pregnant women given prenatal DHA supplementation (meta-analysis pooling RCTs from 2001-2023, general population); birth weight measured in offspring
Effect 72.51 mean difference, 95% CI 37.55 to 107.48
Impact of Omega-3 Fatty Acid Docosahexaenoic Acid Supplementation in Individuals During Pregnancy on Neurodevelopment and Growth of Offspring: Systematic Review and Meta-Analysis.2026PMID:42494300Permalink
Decreases triglycerides
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“The results showed that both EPA and DHA were effective at lowering serum triglycerides (TG) levels.”
Quoted verbatim from Effects of dietary eicosapentaenoic acid and docosahexaenoic acid supplementation on metabolic syndrome: A systematic review and meta-analysis of data from 33 randomized controlled trials.. - Study
- meta-analysis
- Population
- Adults in 33 randomised controlled trials of pure eicosapentaenoic acid or pure docosahexaenoic acid preparations, pooled for features of the metabolic syndrome
Effects of dietary eicosapentaenoic acid and docosahexaenoic acid supplementation on metabolic syndrome: A systematic review and meta-analysis of data from 33 randomized controlled trials.2021PMID:34229258Permalink
Increases tumour necrosis factor alpha concentration
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“DHA supplementation resulted in greater increases in the plasma cytokines IFN-γ and TNF-α compared to placebo (P-interaction < .05).”
Quoted verbatim from The effects of docosahexaenoic acid (DHA) on plasma cytokines, oxylipins, and tumor-infiltrating lymphocytes from women with breast cancer undergoing neoadjuvant chemotherapy in the DHA-WIN trial.. - Study
- RCT
- Duration
- 4 months
- Dose
- DHA-enriched algae, 4.4 g/day, 18 weeks
- Population
- women with breast cancer receiving neoadjuvant chemotherapy (both arms)
The effects of docosahexaenoic acid (DHA) on plasma cytokines, oxylipins, and tumor-infiltrating lymphocytes from women with breast cancer undergoing neoadjuvant chemotherapy in the DHA-WIN trial.2025PMID:40651709Permalink
Accumulates in lung
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Finding“Furthermore, dietary DHA increased pulmonary DHA and its oxylipins while decreasing proinflammatory omega-6 polyunsaturated fatty acids and their oxylipins.”
Quoted verbatim from Docosahexaenoic Acid and Its Metabolites Protect against Ozone-induced Pulmonary Inflammation.. - Study
- animal · not in humans
- Duration
- 6 weeks
- Dose
- DHA-enriched diet, 2% kcal from DHA
- Population
- C57BL/6J mice fed a DHA-enriched diet (2% kcal from DHA) for 6 weeks, then exposed to ozone
Docosahexaenoic Acid and Its Metabolites Protect against Ozone-induced Pulmonary Inflammation.2025PMID:40208640Permalink
Is transported by MFSD2A
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Finding“Unexpectedly, cell-based studies indicate that Mfsd2a transports DHA in the form of lysophosphatidylcholine (LPC), but not unesterified fatty acid, in a sodium-dependent manner.”
Quoted verbatim from Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid.. - Study
- in vitro · not in humans
- Population
- cultured cells (cell type not stated in abstract)
Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid.2014PMID:24828044Permalink
Show the remaining 3
Inhibits FBXW7
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Hypothesis“Mechanistically, DHA inhibited the ubiquitination of NRF1 via the cytoplasmic E3 ligases FBW7 and HRD1 at the ER membrane, thereby preventing its degradation.”
Quoted verbatim from NRF1 is upregulated by docosahexaenoic acid to ameliorate MASH through the inhibition of ER stress.. - Study
- mechanistic · not in humans
- Population
- not stated in the abstract
NRF1 is upregulated by docosahexaenoic acid to ameliorate MASH through the inhibition of ER stress.2026PMID:41545342Permalink
Inhibits SYVN1
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Hypothesis“Mechanistically, DHA inhibited the ubiquitination of NRF1 via the cytoplasmic E3 ligases FBW7 and HRD1 at the ER membrane, thereby preventing its degradation.”
Quoted verbatim from NRF1 is upregulated by docosahexaenoic acid to ameliorate MASH through the inhibition of ER stress.. - Study
- mechanistic · not in humans
- Population
- not stated in the abstract
NRF1 is upregulated by docosahexaenoic acid to ameliorate MASH through the inhibition of ER stress.2026PMID:41545342Permalink
Binds PPARD
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Hypothesis“Molecular docking, molecular dynamics simulations, and mutagenesis experiments suggest that DHA binds to PPARD in a distinct manner compared to OA, which may help explain their differing abilities to influence the expression of heart regeneration genes.”
Quoted verbatim from Accumulation of newly synthesized docosahexaenoic acid plays an essential role in heart regeneration.. - Study
- mechanistic · not in humans
- Population
- computational molecular docking, molecular dynamics simulation, and mutagenesis experiments
Accumulation of newly synthesized docosahexaenoic acid plays an essential role in heart regeneration.2026PMID:40851370Permalink
What did not
1 finding
No detected effect on adverse event occurrence (oral or enteral supplement)
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.FindingNull result“Overall, there were no significant differences in the incidence, type, or severity of adverse effects reported in the placebo or DHA group.”
Quoted verbatim from Safety and efficacy of docosahexaenoic acid supplementation during neoadjuvant breast cancer therapy: Findings from the phase II, double-blind, randomized controlled DHA-WIN trial.. - Study
- RCT
- Duration
- 4 months
- Dose
- 4.4 g/day DHA-enriched algae triacylglycerol (11 x 400 mg capsules/day), oral, concurrent with 6 cycles (18 weeks) of neoadjuvant chemotherapy
- Population
- women with stage I-III non-metastatic breast cancer undergoing neoadjuvant chemotherapy
Safety and efficacy of docosahexaenoic acid supplementation during neoadjuvant breast cancer therapy: Findings from the phase II, double-blind, randomized controlled DHA-WIN trial.2025PMID:40490846Industry fundedPermalink
What it touches on the way
Mechanistic reach
40 entities
40 entities reached.
0 reported hops40 assembled from the scaffold
- ALOX5ProteinUNIPROT:P09917substrate ofInferred only165 paths55 endpoints
- CYP2E1ProteinUNIPROT:P05181metabolized byInferred only126 paths44 endpoints
- PTGS2ProteinUNIPROT:P35354substrate ofInferred only106 paths53 endpoints
- FABP5ProteinUNIPROT:Q01469transported byInferred only101 paths93 endpoints
- ALOX15ProteinUNIPROT:P16050substrate ofInferred only96 paths32 endpoints
- CYP3A4ProteinUNIPROT:P08684metabolized byInferred only94 paths47 endpoints
- ACSL3ProteinUNIPROT:O95573substrate ofInferred only87 paths29 endpoints
- ABCD3ProteinUNIPROT:P28288transported byInferred only87 paths82 endpoints
- CD36ProteinUNIPROT:P16671transported byInferred only82 paths77 endpoints
- CYP2C19ProteinUNIPROT:P33261metabolized byInferred only78 paths26 endpoints
- CYP2C8ProteinUNIPROT:P10632metabolized byInferred only74 paths37 endpoints
- ACSL4ProteinUNIPROT:O60488substrate ofInferred only69 paths23 endpoints
Show the remaining 28
- SLC27A2ProteinUNIPROT:O14975substrate ofInferred only66 paths22 endpoints
- ACSL1ProteinUNIPROT:P33121substrate ofInferred only60 paths30 endpoints
- CYP1A1ProteinUNIPROT:P04798metabolized byInferred only52 paths26 endpoints
- CYP4F8ProteinUNIPROT:P98187metabolized byInferred only52 paths13 endpoints
- CYP4F12ProteinUNIPROT:Q9HCS2metabolized byInferred only52 paths13 endpoints
- CYP2D6ProteinUNIPROT:P10635metabolized byInferred only48 paths24 endpoints
- SLC27A3ProteinUNIPROT:Q5K4L6transported byInferred only48 paths24 endpoints
- ABCA1ProteinUNIPROT:O95477transported byInferred only47 paths47 endpoints
- CYP1A2ProteinUNIPROT:P05177metabolized byInferred only39 paths39 endpoints
- CYP4F3ProteinUNIPROT:Q08477metabolized byInferred only32 paths16 endpoints
- CYP2J2ProteinUNIPROT:P51589metabolized byInferred only30 paths15 endpoints
- ALOX12ProteinUNIPROT:P18054substrate ofInferred only28 paths28 endpoints
- ACSL6ProteinUNIPROT:Q9UKU0substrate ofInferred only22 paths11 endpoints
- ACSL5ProteinUNIPROT:Q9ULC5substrate ofInferred only22 paths11 endpoints
- FBXW7ProteinUNIPROT:Q969H0inhibitsInferred only19 paths19 endpoints
- CYP4F2ProteinUNIPROT:P78329metabolized byInferred only18 paths18 endpoints
- ACSBG1ProteinUNIPROT:Q96GR2substrate ofInferred only14 paths7 endpoints
- CYP4F11ProteinUNIPROT:Q9HBI6metabolized byInferred only13 paths13 endpoints
- ACSBG2ProteinUNIPROT:Q5FVE4substrate ofInferred only12 paths6 endpoints
- CYP4V2ProteinUNIPROT:Q6ZWL3metabolized byInferred only10 paths10 endpoints
- FABP3ProteinUNIPROT:P05413transported byInferred only9 paths9 endpoints
- DAGLBProteinUNIPROT:Q8NCG7substrate ofInferred only9 paths9 endpoints
- SLC27A6ProteinUNIPROT:Q9Y2P4transported byInferred only8 paths4 endpoints
- ALOX12BProteinUNIPROT:O75342substrate ofInferred only8 paths8 endpoints
- FABP4ProteinUNIPROT:P15090transported byInferred only6 paths6 endpoints
- MFSD2AProteinUNIPROT:Q8NA29transported byInferred only6 paths6 endpoints
- SLC27A4ProteinUNIPROT:Q6P1M0transported byInferred only4 paths2 endpoints
- FABP1ProteinUNIPROT:P07148transported byInferred only3 paths3 endpoints
What the reference databases state
Chemical structure
- 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-N-(acetyl)-sphing-4-enine has the functional parent all-cis-docosa-4,7,10,13,16,19-hexaenoic acidCompoundChEBI CHEBI:76087Inferred only
- 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine has the functional parent all-cis-docosa-4,7,10,13,16,19-hexaenoic acidCompoundChEBI CHEBI:74963Inferred only
- 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol has the functional parent all-cis-docosa-4,7,10,13,16,19-hexaenoic acidCompoundChEBI CHEBI:82949Inferred only
- 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine has the functional parent all-cis-docosa-4,7,10,13,16,19-hexaenoic acidCompoundChEBI CHEBI:84829Inferred only
- 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol has the functional parent all-cis-docosa-4,7,10,13,16,19-hexaenoic acidCompoundChEBI CHEBI:77129Inferred only
- 1-tetradecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine has the functional parent all-cis-docosa-4,7,10,13,16,19-hexaenoic acidCompoundChEBI CHEBI:86162Inferred only
- 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine has the functional parent all-cis-docosa-4,7,10,13,16,19-hexaenoic acidCompoundChEBI CHEBI:76085Inferred only
- N-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl ethanolamine has the functional parent all-cis-docosa-4,7,10,13,16,19-hexaenoic acidCompoundChEBI CHEBI:85252Inferred only
Statements
89 statements
89 statements · 2 reference databases · Subject: all-cis-docosa-4,7,10,13,16,19-hexaenoic acid · Sources: Human-GEM, Rhea
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is converted to (11S)-hydroperoxy-(4Z,7Z,9E,13Z,16Z,19Z)-docosahexaenoateCompoundRhea RHEA:64732Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is converted to (14S)-hydroperoxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoateCompoundRhea RHEA:41332Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is converted to (17S)-hydroperoxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoateCompoundRhea RHEA:50840Inferred only
- (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA is converted to all-cis-docosa-4,7,10,13,16,19-hexaenoic acidCompoundRhea RHEA:67700Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is converted to (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoACompoundRhea RHEA:44932Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is converted to (7S)-hydroperoxy-(4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoateCompoundRhea RHEA:64668Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is converted to 14-hydroperoxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoateCompoundRhea RHEA:43472Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is converted to 21-hydroxy-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoateCompoundHuman-GEM MAR20025Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is converted to 21-hydroxy-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoateCompoundHuman-GEM MAR20026Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP1A1ProteinRhea RHEA:52120Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP1A1ProteinRhea RHEA:52124Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP1A2ProteinRhea RHEA:52120Inferred only
Show the remaining 77
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP2C19ProteinRhea RHEA:50088Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP2C19ProteinRhea RHEA:52120Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP2C19ProteinRhea RHEA:52124Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP2C8ProteinRhea RHEA:52120Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP2C8ProteinRhea RHEA:52124Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP2D6ProteinRhea RHEA:52124Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP2D6ProteinRhea RHEA:52120Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP2E1ProteinHuman-GEM MAR20025Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP2E1ProteinHuman-GEM MAR20026Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP2E1ProteinRhea RHEA:50088Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP2J2ProteinRhea RHEA:52120Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP2J2ProteinRhea RHEA:52124Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP3A4ProteinRhea RHEA:52120Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP3A4ProteinRhea RHEA:52124Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP4F11ProteinRhea RHEA:40155Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP4F12ProteinRhea RHEA:51084Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP4F12ProteinRhea RHEA:51092Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP4F12ProteinRhea RHEA:51088Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP4F12ProteinRhea RHEA:51080Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP4F2ProteinRhea RHEA:40155Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP4F3ProteinRhea RHEA:50088Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP4F3ProteinRhea RHEA:40155Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP4F8ProteinRhea RHEA:51092Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP4F8ProteinRhea RHEA:51084Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP4F8ProteinRhea RHEA:51088Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP4F8ProteinRhea RHEA:51080Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is metabolised by CYP4V2ProteinRhea RHEA:40155Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of ACSBG1ProteinHuman-GEM MAR02988Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of ACSBG1ProteinHuman-GEM MAR00377Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of ACSBG2ProteinHuman-GEM MAR02988Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of ACSBG2ProteinHuman-GEM MAR00377Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of ACSL1ProteinHuman-GEM MAR00377Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of ACSL1ProteinHuman-GEM MAR02988Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of ACSL3ProteinHuman-GEM MAR02988Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of ACSL3ProteinRhea RHEA:44932Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of ACSL3ProteinHuman-GEM MAR00377Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of ACSL4ProteinHuman-GEM MAR02988Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of ACSL4ProteinRhea RHEA:44932Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of ACSL4ProteinHuman-GEM MAR00377Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of ACSL5ProteinHuman-GEM MAR02988Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of ACSL5ProteinHuman-GEM MAR00377Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of ACSL6ProteinHuman-GEM MAR00377Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of ACSL6ProteinHuman-GEM MAR02988Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of ALOX12ProteinRhea RHEA:41332Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of ALOX12BProteinRhea RHEA:43472Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of ALOX15ProteinRhea RHEA:41332Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of ALOX15ProteinRhea RHEA:50840Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of ALOX15ProteinRhea RHEA:64732Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of ALOX5ProteinRhea RHEA:64668Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of ALOX5ProteinRhea RHEA:50840Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of ALOX5ProteinRhea RHEA:41332Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of DAGLBProteinRhea RHEA:63436Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of PTGS2ProteinRhea RHEA:48816Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of PTGS2ProteinRhea RHEA:48820Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of SLC27A2ProteinHuman-GEM MAR02988Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of SLC27A2ProteinHuman-GEM MAR00377Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a substrate of SLC27A2ProteinRhea RHEA:44932Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is transported by ABCA1ProteinHuman-GEM MAR00379Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is transported by ABCD3ProteinRhea RHEA:67704Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is transported by CD36ProteinHuman-GEM MAR00376Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is transported by FABP1ProteinHuman-GEM MAR00376Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is transported by FABP12ProteinHuman-GEM MAR00376Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is transported by FABP2ProteinHuman-GEM MAR00376Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is transported by FABP3ProteinHuman-GEM MAR00376Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is transported by FABP4ProteinHuman-GEM MAR00376Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is transported by FABP5ProteinHuman-GEM MAR00376Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is transported by FABP6ProteinHuman-GEM MAR00376Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is transported by FABP7ProteinHuman-GEM MAR00376Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is transported by FABP9ProteinHuman-GEM MAR00376Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is transported by SLC27A1ProteinHuman-GEM MAR08945Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is transported by SLC27A1ProteinHuman-GEM MAR00376Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is transported by SLC27A3ProteinHuman-GEM MAR08945Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is transported by SLC27A3ProteinHuman-GEM MAR00376Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is transported by SLC27A4ProteinHuman-GEM MAR08945Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is transported by SLC27A4ProteinHuman-GEM MAR00376Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is transported by SLC27A6ProteinHuman-GEM MAR00376Inferred only
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid is transported by SLC27A6ProteinHuman-GEM MAR08945Inferred only
Reactions
67 reactions
fatty acid0.0001MAM00003e+0.0001(11Z,14Z)-eicosadienoate+0.0001MAM00010e+0.0001MAM00017e+0.0001MAM00019e+0.0001MAM00021e+0.0001MAM00094e+0.0001MAM00104e+0.0001MAM00111e+0.0001MAM00114e+0.0001MAM00115e+0.0001MAM00117e+0.0001MAM00128e+0.0001MAM00132e+0.0001MAM00135e+0.0001MAM00260e+0.0001MAM00265e+0.0001MAM00315e+0.0001MAM00341e+0.0001MAM01197e+0.0001MAM01207e+0.0001MAM01235e+0.0001MAM01238e+0.0001(7Z,10Z,13Z,16Z)-docosatetraenoate+0.0082(5Z,8Z,11Z,14Z)-eicosatetraenoate+0.0001docosanoate+0.0001hexacosanoate+0.0001MAM01582e+0.0001MAM01583e+0.0001(11Z)-eicosenoate+0.0001MAM01585e+0.0041all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+0.002(8Z,11Z,14Z)-eicosatrienoate+0.0001(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate+0.0001eicosanoate+0.0001elaidic acid+0.001(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate+0.0001MAM01932e+0.0001MAM02053e+0.0001dodecanoate+0.0001tetracosanoate+0.1535linoleic acid+0.0092alpha-linolenic acid+0.0001MAM02456e+0.0001(5Z,8Z,11Z)-eicosatrienoate+0.0338tetradecanoate+0.0001(15Z)-tetracosenoate+0.0001MAM02613e+0.3837(9Z)-octadecenoate+0.0001MAM02648e+0.3015hexadecanoic acid+0.0522(9Z)-hexadecenoate+0.0001MAM02690e+0.0001MAM02745e+0.046octadecanoate+0.0001MAM02939e+0.0001tricosanoate+0.0001MAM03051e+0.0001(17Z)-hexacosenoate
Reaction pageLeft to rightBalance undeterminableextracellular space
Human-GEM MAR00012CC BY 4.0Reference data
MAM02560e0.0048MAM00003e+0.0016(11Z,14Z)-eicosadienoate+0.0016MAM00010e+0.0001MAM00017e+0.0001MAM00019e+0.0001MAM00021e+0.0001MAM00094e+0.0001MAM00104e+0.0001MAM00111e+0.0001MAM00114e+0.0001MAM00115e+0.0001MAM00117e+0.0001MAM00128e+0.0001MAM00132e+0.0001MAM00135e+0.0001MAM00260e+0.0001MAM00265e+0.0001MAM00315e+0.0001MAM00341e+0.0001MAM01197e+0.0001MAM01207e+0.0001MAM01235e+0.0001MAM01238e+0.0017(7Z,10Z,13Z,16Z)-docosatetraenoate+0.0137(5Z,8Z,11Z,14Z)-eicosatetraenoate+0.0007docosanoate+0.0005hexacosanoate+0.0001MAM01582e+0.0002MAM01583e+0.0001(11Z)-eicosenoate+0.0001MAM01585e+0.0046all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+0.0025(8Z,11Z,14Z)-eicosatrienoate+0.0019(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate+0.0011eicosanoate+0.0001elaidic acid+0.002(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate+0.0048MAM01932e+0.0001MAM02053e+0.0034dodecanoate+0.0012tetracosanoate+0.071linoleic acid+0.0005alpha-linolenic acid+0.0056MAM02456e+0.0005(5Z,8Z,11Z)-eicosatrienoate+0.0283tetradecanoate+0.0003(15Z)-tetracosenoate+0.0001MAM02613e+0.3746(9Z)-octadecenoate+0.0001MAM02648e+0.2949hexadecanoic acid+0.0686(9Z)-hexadecenoate+0.003MAM02690e+0.0001MAM02745e+0.1031octadecanoate+0.0001MAM02939e+0.0002tricosanoate+0.0001MAM03051e+0.0001(17Z)-hexacosenoate
Reaction pageLeft to rightBalance undeterminableextracellular space
Human-GEM MAR00015CC BY 4.0Reference data
0.0001MAM00003e+0.0023(11Z,14Z)-eicosadienoate+0.0003MAM00010e+0.0002MAM00017e+0.003MAM00019e+0.0001MAM00021e+0.0001MAM00094e+0.0001MAM00104e+0.0001MAM00111e+0.0001MAM00114e+0.0001MAM00115e+0.0004MAM00117e+0.0023MAM00128e+0.0001MAM00132e+0.0001MAM00135e+0.0001MAM00260e+0.0001MAM00265e+0.0001MAM00315e+0.0001MAM00341e+0.0045MAM01197e+0.0002MAM01207e+0.001MAM01235e+0.0037MAM01238e+0.0008(7Z,10Z,13Z,16Z)-docosatetraenoate+0.0051(5Z,8Z,11Z,14Z)-eicosatetraenoate+0.0002docosanoate+0.0001hexacosanoate+0.0001MAM01582e+0.0002MAM01583e+0.0046(11Z)-eicosenoate+0.0204MAM01585e+0.0012all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+0.0021(8Z,11Z,14Z)-eicosatrienoate+0.0009(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate+0.0009eicosanoate+0.0001elaidic acid+0.0009(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate+0.0005MAM01932e+0.0001MAM02053e+0.0061dodecanoate+0.0001tetracosanoate+0.1573linoleic acid+0.0073alpha-linolenic acid+0.0001MAM02456e+0.0001(5Z,8Z,11Z)-eicosatrienoate+0.035tetradecanoate+0.0001(15Z)-tetracosenoate+0.0001MAM02613e+0.383(9Z)-octadecenoate+0.0004MAM02648e+0.2478hexadecanoic acid+0.0395(9Z)-hexadecenoate+0.0039MAM02690e+0.0001MAM02745e+0.0613octadecanoate+0.0001MAM02939e+0.0001tricosanoate+0.0001MAM03051e+0.0001(17Z)-hexacosenoateMAM02561e
Reaction pageLeft to rightBalance undeterminableextracellular space
Human-GEM MAR00016CC BY 4.0Reference data
all-cis-docosa-4,7,10,13,16,19-hexaenoic acidall-cis-docosa-4,7,10,13,16,19-hexaenoic acid
Transported by SLC27A6 or FABP3 or SLC27A1 or CD36 or SLC27A3 or FABP2 or FABP1 or FABP7 or FABP5 or SLC27A4 or FABP6 or FABP4 and 2 more alternatives
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR00376CC BY 4.0Reference data
ATP+CHEBI:1146900+all-cis-docosa-4,7,10,13,16,19-hexaenoic acid(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA+AMP+diphosphate(3-)
Catalysed by ACSL4 or ACSBG1 or ACSL3 or ACSBG2 or SLC27A2 or ACSL1 or ACSL6 or ACSL5
Reaction pageLeft to rightBalancedEC 6.2.1.3cytosol
Human-GEM MAR00377CC BY 4.0Reference data
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA+waterCHEBI:1146900+all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+proton
Reaction pageLeft to rightBalancedEC 3.1.2.2cytosol
Human-GEM MAR00378CC BY 4.0Reference data
ATP+all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+waterADP+all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+proton+phosphate(3-)
Transported by ABCA1
Reaction pageLeft to rightBalancedcytosol, extracellular space
Human-GEM MAR00379CC BY 4.0Reference data
all-cis-docosa-4,7,10,13,16,19-hexaenoic acid
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR00573CC BY 4.0Reference data
fatty acid0.0001MAM00003c+0.0001(11Z,14Z)-eicosadienoate+0.0001MAM00010c+0.0001MAM00017c+0.0001MAM00019c+0.0001MAM00021c+0.0001MAM00094c+0.0001MAM00104c+0.0001MAM00111c+0.0001MAM00114c+0.0001MAM00115c+0.0001MAM00117c+0.0001MAM00128c+0.0001MAM00132c+0.0001MAM00135c+0.0001MAM00260c+0.0001MAM00265c+0.0001MAM00315c+0.0001MAM00341c+0.0001MAM01197c+0.0001MAM01207c+0.0001MAM01235c+0.0001MAM01238c+0.0001(7Z,10Z,13Z,16Z)-docosatetraenoate+0.0024(5Z,8Z,11Z,14Z)-eicosatetraenoate+0.0001docosanoate+0.0001hexacosanoate+0.0001MAM01582c+0.0001MAM01583c+0.0001(11Z)-eicosenoate+0.0208MAM01585c+0.0005all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+0.0013(8Z,11Z,14Z)-eicosatrienoate+0.0017(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate+0.0001eicosanoate+0.0001elaidic acid+0.0013(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate+0.0048MAM01932c+0.0001MAM02053c+0.0001dodecanoate+0.0001tetracosanoate+0.0741linoleic acid+0.0037alpha-linolenic acid+0.0001MAM02456c+0.0001(5Z,8Z,11Z)-eicosatrienoate+0.0096tetradecanoate+0.0001(15Z)-tetracosenoate+0.0001MAM02613c+0.122(9Z)-octadecenoate+0.0001MAM02648c+0.64hexadecanoic acid+0.0286(9Z)-hexadecenoate+0.0001MAM02690c+0.0001MAM02745c+0.082octadecanoate+0.0028MAM02939c+0.0001tricosanoate+0.0001MAM03051c+0.0001(17Z)-hexacosenoate
Reaction pageLeft to rightBalance undeterminablecytosol
Human-GEM MAR00685CC BY 4.0Reference data
fatty acid0.0001MAM00003c+0.0001(11Z,14Z)-eicosadienoate+0.0001MAM00010c+0.0001MAM00017c+0.0001MAM00019c+0.0001MAM00021c+0.0016MAM00094c+0.0001MAM00104c+0.0001MAM00111c+0.0001MAM00114c+0.0001MAM00115c+0.0001MAM00117c+0.0001MAM00128c+0.0001MAM00132c+0.0001MAM00135c+0.0001MAM00260c+0.0001MAM00265c+0.0001MAM00315c+0.0001MAM00341c+0.0001MAM01197c+0.0001MAM01207c+0.0001MAM01235c+0.0001MAM01238c+0.0032(7Z,10Z,13Z,16Z)-docosatetraenoate+0.0521(5Z,8Z,11Z,14Z)-eicosatetraenoate+0.0001docosanoate+0.0001hexacosanoate+0.0001MAM01582c+0.0001MAM01583c+0.0001(11Z)-eicosenoate+0.0217MAM01585c+0.0081all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+0.0023(8Z,11Z,14Z)-eicosatrienoate+0.0018(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate+0.0001eicosanoate+0.0001elaidic acid+0.0003(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate+0.003MAM01932c+0.0001MAM02053c+0.0001dodecanoate+0.0001tetracosanoate+0.281linoleic acid+0.0119alpha-linolenic acid+0.0001MAM02456c+0.0001(5Z,8Z,11Z)-eicosatrienoate+0.0024tetradecanoate+0.0001(15Z)-tetracosenoate+0.0001MAM02613c+0.4226(9Z)-octadecenoate+0.0001MAM02648c+0.12hexadecanoic acid+0.0229(9Z)-hexadecenoate+0.0001MAM02690c+0.0001MAM02745c+0.0384octadecanoate+0.0025MAM02939c+0.0001tricosanoate+0.0001MAM03051c+0.0001(17Z)-hexacosenoate
Reaction pageLeft to rightBalance undeterminablecytosol
Human-GEM MAR00686CC BY 4.0Reference data
fatty acid0.0001MAM00003c+0.0001(11Z,14Z)-eicosadienoate+0.0001MAM00010c+0.0001MAM00017c+0.0001MAM00019c+0.0001MAM00021c+0.0011MAM00094c+0.0001MAM00104c+0.0001MAM00111c+0.0001MAM00114c+0.0001MAM00115c+0.0001MAM00117c+0.0001MAM00128c+0.0001MAM00132c+0.0001MAM00135c+0.0001MAM00260c+0.0001MAM00265c+0.0001MAM00315c+0.0001MAM00341c+0.0001MAM01197c+0.0001MAM01207c+0.0001MAM01235c+0.0001MAM01238c+0.0022(7Z,10Z,13Z,16Z)-docosatetraenoate+0.0264(5Z,8Z,11Z,14Z)-eicosatetraenoate+0.0001docosanoate+0.0001hexacosanoate+0.0001MAM01582c+0.0001MAM01583c+0.0001(11Z)-eicosenoate+0.0194MAM01585c+0.0221all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+0.0141(8Z,11Z,14Z)-eicosatrienoate+0.0038(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate+0.0001eicosanoate+0.0001elaidic acid+0.0035(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate+0.0081MAM01932c+0.0001MAM02053c+0.0001dodecanoate+0.0001tetracosanoate+0.278linoleic acid+0.0023alpha-linolenic acid+0.0001MAM02456c+0.0001(5Z,8Z,11Z)-eicosatrienoate+0.003tetradecanoate+0.0001(15Z)-tetracosenoate+0.0001MAM02613c+0.4519(9Z)-octadecenoate+0.0001MAM02648c+0.0849hexadecanoic acid+0.014(9Z)-hexadecenoate+0.0001MAM02690c+0.0001MAM02745c+0.0584octadecanoate+0.0026MAM02939c+0.0001tricosanoate+0.0001MAM03051c+0.0001(17Z)-hexacosenoate
Reaction pageLeft to rightBalance undeterminablecytosol
Human-GEM MAR00687CC BY 4.0Reference data
fatty acid0.0005MAM00003c+0.0005(11Z,14Z)-eicosadienoate+0.0005MAM00010c+0.0005MAM00017c+0.0005MAM00019c+0.0005MAM00021c+0.0039MAM00094c+0.0005MAM00104c+0.0005MAM00111c+0.0005MAM00114c+0.0005MAM00115c+0.0005MAM00117c+0.0005MAM00128c+0.0005MAM00132c+0.0005MAM00135c+0.0005MAM00260c+0.0005MAM00265c+0.0005MAM00315c+0.0005MAM00341c+0.0005MAM01197c+0.0005MAM01207c+0.0005MAM01235c+0.0005MAM01238c+0.0011(7Z,10Z,13Z,16Z)-docosatetraenoate+0.0709(5Z,8Z,11Z,14Z)-eicosatetraenoate+0.0005docosanoate+0.0005hexacosanoate+0.0005MAM01582c+0.0005MAM01583c+0.0005(11Z)-eicosenoate+0.0271MAM01585c+0.0252all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+0.0228(8Z,11Z,14Z)-eicosatrienoate+0.0056(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate+0.0005eicosanoate+0.0005elaidic acid+0.0109(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate+0.0036MAM01932c+0.0005MAM02053c+0.0005dodecanoate+0.0005tetracosanoate+0.2479linoleic acid+0.0047alpha-linolenic acid+0.0005MAM02456c+0.0005(5Z,8Z,11Z)-eicosatrienoate+0.0054tetradecanoate+0.0005(15Z)-tetracosenoate+0.0005MAM02613c+0.1143(9Z)-octadecenoate+0.0178MAM02648c+0.2781hexadecanoic acid+0.0105(9Z)-hexadecenoate+0.0005MAM02690c+0.0005MAM02745c+0.1271octadecanoate+0.0026MAM02939c+0.0005tricosanoate+0.0005MAM03051c+0.0005(17Z)-hexacosenoate
Reaction pageReversibleBalance undeterminablecytosol
Human-GEM MAR00688CC BY 4.0Reference data
On the label
Labelled products
628 products
Source: NIH DSLD · Ingredient: all-cis-docosa-4,7,10,13,16,19-hexaenoic acid · 628 products · Declared amount per serving: 0.5–3,380 mg (613 products)
623 labels state an amount5 do not
- 1MDKrillMD120 mgper 2 Softgel(s)DSLD:246767
- 1st PhormMicro Factor EFAFish Oil100 mgper 1 Softgel(s)DSLD:295905
- 21st CenturyDHASchizochytrium sp. Oil200 mgper 1 Softgel(s)DSLD:258550
- 21st CenturyDHASchizochytrium sp. Oil200 mgper 1 Softgel(s)DSLD:282959
- 21st CenturyDHA 200 Plant-Sourced Omega-3Algal Oil · DHA (Form: from Algal Oil) (Alt. Name: Docosahexaenoic Acid)200 mgper 1 Softgel(s)DSLD:11404
- 21st CenturyDHA 300 High Potency Plant-Sourced Omega-3Algal Oil · DHA (Form: from Algal Oil) (Alt. Name: Docosahexaenoic Acid)300 mgper 1 Softgel(s)DSLD:11409
- 21st CenturyOcuHealth Full Spectrum Formula High Potency AntioxidantMarine Algae · DHA (Form: fron Marine Algae) (Alt. Name: Docosahexaenoic Acid)20 mgper 2 Tablet(s)DSLD:11491
- 21st Century VitaJoy GummiesOmega + DHAAlgae · DHA (Form: from Algae)50 mgper 3 Gummy(ies)DSLD:207612
- 21st Century Zoo FriendsSmart Kids Omega plus DHAAlgae · DHA (Form: from Algae)16.7 mgper 1 Gummy(ies)DSLD:207608
- 8WeeksOutIntellect100 mgper 3 Capsule(s)DSLD:228495
- AB American BiologicsImproved Super Omega EPA/DHADHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3240 mgper 2 Softgel(s)DSLD:20294
- AB American BiologicsUltra Omega EssentialsDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3110 mgper 2 Softgel(s)DSLD:20491
Show the remaining 616
- AbbottDHA/Lutein/Vitamin E SoftgelFish Oil Concentrate · DHA (Form: from Fish Oil concentrate (Form: Anchovy, Sardine, Jack Mackerel, Tuna)) (Alt. Name: Docosahexaenoic Acid)200 mgper 1 Softgel(s)DSLD:69993
- AbbottDHA/Lutein/Vitamin E SoftgelFish Oil Concentrate · DHA (Form: from Fish Oil concentrate (Form: Anchovy, Sardine, Jack Mackerel, Tuna)) (Alt. Name: Docosahexaenoic Acid)200 mgper 1 Softgel(s)DSLD:69999
- Abbott NutritionSimilac Breastfeeding SupplementFish Oil Concentrate200 mgper 1 Softgel(s)DSLD:270268
- Absorb HealthOmega DHA & EPADHA (Alt. Name: Docosahexaenoic Acid) Note: Gas Chromatography by A%.480 mgper 2 Softgel(s)DSLD:216055
- Acella PharmaceuticalsPNV DHADocosahexaenoic Acid (Form: from Omega-3 Fatty Acids) (Alt. Name: DHA)300 mgper 1 Softgel(s)DSLD:239560
- Acella PharmaceuticalsPNV-DHADocosahexaenoic Acid (Form: from Omega-3 Fatty Acids) (Alt. Name: DHA)300 mgper 1 Tablet(s)DSLD:45702
- Acella PharmaceuticalsPNV-Omega300 mgper 1 Softgel(s)DSLD:278709
- Advanced Nutrition by ZahlerMighty MiniAlgal Oil100 mgper 1 Softgel(s)DSLD:260232
- AdvoCareCore Nutrition SystemMarine Lipids · Docosahexaenoic Acid (Form: from Marine Lipids)400 mgper 1 4-Packet Strip(s)DSLD:177397
- AdvoCareMNS 3Marine Lipids · Docosahexaenoic Acid (Form: from Marine Lipids)400 mgper 2 Packet(s)DSLD:177961
- AdvoCareMNS CMarine Lipids · Docosahexaenoic Acid (Form: from Marine Lipids)200 mgper 2 Packet(s)DSLD:207148
- AdvoCareMNS EMarine Lipids · Docosahexaenoic Acid (Form: from Marine Lipids)200 mgper 1 Packet(s)DSLD:177964
- AdvoCareOmegaPlexMarine Lipids400 mgper 2 Softgel(s)DSLD:265350
- AdvoCarePurple Champs Acai Berry80 mgper 2 Chew(s)DSLD:178345
- Alani NuPrenatal200 mgper 2 Softgel(s)DSLD:277637
- Allergy Research GroupSteady On110 mgper 20 Gram(s)DSLD:54474
- Allergy Research GroupSteady On110 mgper 20 Gram(s)DSLD:54482
- Allergy Research GroupTake Heart II Without Hormones95 mgper 20 Gram(s)DSLD:54484
- Allergy Research GroupTake Heart II Without Hormones95 mgper 20 Gram(s)DSLD:54477
- Amala VeganKids Vegan Omega 3 DHA + EPA Organic Lemon Flavored250 mgper 0.5 mLDSLD:276164
- AmerifitDHA SoftgelAlgal Oil · DHA (Form: from Algal Oil) (Alt. Name: Docosahexaenoic Acid)350 mgper 1 Softgel(s)DSLD:29021
- AmeriFitBrainStrong KidsAlgal Oil · DHA Note: docosahexaenoic acid from algal oil100 mgper 1 Gummy(ies)DSLD:2494
- AmeriFitBrainStrong ToddlerAlgal Oil · DHA Note: docosahexaenoic acid from algal oil100 mgper 1 Packet(s)DSLD:2495
- AmvilabOmega 3-6-9Fish Oil100 mgper 1 Softgel(s)DSLD:298165
- AN Amazing Nutrition Amazing OmegaFish Oil 1000 mg22%120 mgper 1 Softgel(s)DSLD:275821
- AN Amazing Nutrition Amazing OmegaKrill Oil 500 mg32 mgper 1 Softgel(s)DSLD:251769
- ANTIAGING Institute of CaliforniaFish Oil Concentrate120 mgper 1 Softgel(s)DSLD:210294
- AOR Advanced Orthomolecular Research PremiumVegan Omega 3Typical values. Ranges: DHA 300-400 mg316 mgper 1 Softgel(s)DSLD:305920
- Apex EnergeticsOmegaCo3 (K-7)350 mgper 1 TbspDSLD:206624
- Apex EnergeticsOmegaCo3-SE375 mgper 2 Softgel(s)DSLD:239380
- AquaOmegaHigh DHA Omega-3 4500 mg Lemon Flavor3,380 mgper 7.5 mLDSLD:277089
- AquaOmegaHigh EPA Omega-3 Lemon Flavor670 mgper 7.5 mLDSLD:275942
- AquaOmegaHigh EPA Omega-3 Orange Flavor670 mgper 7.5 mLDSLD:275944
- aSquared NutritionOmega 3 2400 mg Lemon Flavored430 mgper 2 Softgel(s)DSLD:322074
- Avion PharmaceuticalsPrenate DHAFish Oil · Docosahexaenoic Acid (Form: from Omega-3 Fatty Acids (Form: from Fish Oil)) (Alt. Name: DHA)300 mgper 1 Softgel(s)DSLD:25833
- Avion PharmaceuticalsPrenate DHA300 mgper 1 Softgel(s)DSLD:279278
- Avion PharmaceuticalsPrenate DHA300 mgper 1 Softgel(s)DSLD:44767
- Avion PharmaceuticalsPrenate Enhance400 mgper 1 Softgel(s)DSLD:279277
- Avion PharmaceuticalsPrenate Enhance400 mgper 1 Softgel(s)DSLD:44772
- Avion PharmaceuticalsPrenate Essential300 mgper 1 Softgel(s)DSLD:279279
- Avion PharmaceuticalsPrenate Essential300 mgper 1 Softgel(s)DSLD:44774
- Avion PharmaceuticalsPrenate Mini350 mgper 1 Softgel(s)DSLD:44778
- Avion PharmaceuticalsPrenate Pixie200 mgper 1 Soft Gel(s)DSLD:279281
- Avion PharmaceuticalsPrenate Pixie200 mgper 1 Softgel(s)DSLD:44781
- Avion PharmaceuticalsPrenate Restore400 mgper 1 Softgel(s)DSLD:278690
- Avion PharmaceuticalsPrenate Restore400 mgper 1 Softgel(s)DSLD:44997
- Avion PharmaceuticalsPrimaCare300 mgper 1 Softgel(s)DSLD:278712
- Barlean'sTotal Omega 3-6-9 Lemonade Flavor200 mgper 3 Gram(s)DSLD:218507
- Barlean's Organic OilsIdeal Omega 3 Orange Flavored250 mgper 1 Softgel(s)DSLD:220029
- Basic VitaminsOderless Coated Fish Oil 1000 mg Omega-3120 mgper 1 Softgel(s)DSLD:250298
- BayerArctic Wonder Omega-3 Krill Oil90 mgper 2 Softgel(s)DSLD:12238
- BayerFlintstones Gummies Complete plus Omega-3 DHAAlgal Oil · DHA (Form: from Algal Oil) (Alt. Name: Docosahexaenoic Acid)32 mgper 1 Gummy(ies)DSLD:45138
- BayerFlintstones SupplementsAlgal Oil · DHA (Form: from Algal Oil) (Alt. Name: Docosahexaenoic Acid)100 mgper 1 Gummy(ies)DSLD:70315
- Bayer One A DayVitaCraves Gummies +Omega-3 DHA Fruit Punch FlavoredAlgal Oil · DHA (Form: from Algal Oil) (Alt. Name: Docosahexaenoic Acid)32 mgper 2 Gummy(ies)DSLD:17180
- Bayer One A DayWomen's Prenatal Gummies50 mgper 2 Gummy(ies)DSLD:270736
- Bayer One A DayWomen's Prenatal Gummies with Folic Acid50 mgper 2 Gummie(s)DSLD:269824
- Bayer One A Day AdultVitaCraves Multi + Omega-3 DHA Gummies Fruit Punch FlavorAlgal Oil · DHA (Form: from Algal Oil) (Alt. Name: Docosahexaenoic Acid)32 mgper 2 Gummie(s)DSLD:178148
- Best NaturalsKrill-500 1000 mgTypical fatty Acid104 mgper 1 Softgel(s)DSLD:270590
- Best NaturalsKrill-500 500 mgTypical fatty Acid104 mgper 2 Softgel(s)DSLD:270589
- Best Nest WellnessOne Fish, Two Fish500 mgper 2 Softgel(s)DSLD:270752
- Beyond HealthFish Oil Formula500 mgper 2 Softgel(s)DSLD:306889
- Beyond HumanOmega 3 Fish Oil120 mgper 1 Soft Gelatin Capsule(s)DSLD:181952
- Bio NutritionBrain WellnessDHA Note: Source: Veg50 mgper 2 Vegetable Capsule(s)DSLD:200631
- Bio NutritionK Bio Krill 500 mg52 mgper 1 Softgel(s)DSLD:200593
- BioChem SportsOmega BurnMarine Lipids · Docosahexaenoic acid (Form: from marine lipid (Form: Anchovy, Sardine, Mackerel, algae (Form: Chrysophyceae))) (Alt. Name: DHA)233 mgper 6 Softgel(s)DSLD:13312
- BIOVEADHA 100 mgFish Oil · Docosahexaenoic Acid (Form: from Fish Oil) (Alt. Name: DHA)100 mgper 1 Softgel(s)DSLD:249071
- BIOVEAPrenatal Multi with DHAFish Oil · DHA (Form: from Fish Oil)25 mgper 3 Tablet(s)DSLD:45457
- BluebonnetLadies One Prenatal DHAAlgal Oil200 mgper 1 Vegetarian Softgel(s)DSLD:332515
- BluebonnetLadies One Prenatal DHA 200 mgAlgal Oil200 mgper 1 Vegetarian Softgel(s)DSLD:332514
- BluebonnetNatural Omega-3 Vegetarian DHA 100 mgAlgal Oil · DHA (Form: from Algal Oil) (Alt. Name: Docosahexaenoic Acid)100 mgper 1 Vegetarian Capsule(s)DSLD:178926
- BluebonnetNatural Omega-3 Vegetarian DHA 100 mgAlgal Oil · DHA (Form: from Algal Oil) (Alt. Name: Docosahexaenoic Acid)100 mgper 1 Vegetarian Softgel(s)DSLD:178936
- BluebonnetNatural Omega-3 Vegetarian DHA 200 mgAlgal Oil · DHA (Form: from Algal Oil) (Alt. Name: Docosahexaenoic Acid)200 mgper 1 Vegetarian Softgel(s)DSLD:178937
- BluebonnetOmega-3 Vegetarian DHA 200 mgAlgal Oil200 mgper 1 Vegetarian Softgel(s)DSLD:280178
- BluebonnetOmega-3 Vegetarian DHA 200 mgAlgal Oil200 mgper 1 Vegetarian Softgel(s)DSLD:316455
- Bluebonnet Early Promise PrenatalGentle DHA 100 mgAlgal Oil · DHA (Form: from Algal Oil) (Alt. Name: Docosahexaenoic Acid)100 mgper 1 Vegetarian Softgel(s)DSLD:176715
- Bluebonnet Early Promise PrenatalGentle DHA 100 mgAlgal Oil · DHA (Form: from Algal Oil) (Alt. Name: Docosahexaenoic Acid)100 mgper 1 Vegetarian Softgel(s)DSLD:176718
- Bluebonnet Early Promise PrenatalGentle DHA 200 mgAlgal Oil · DHA (Form: from Algal Oil) (Alt. Name: Docosahexaenoic Acid)200 mgper 1 Vegetarian Softgel(s)DSLD:176709
- Bluebonnet Early Promise PrenatalGentle DHA 200 mgAlgal Oil · DHA (Form: from Algal Oil) (Alt. Name: Docosahexaenoic Acid)200 mgper 1 Vegetarian Softgel(s)DSLD:176785
- Bluebonnet Early Promise PrenatalGentle DHA 200 mgAlgal Oil200 mgper 1 Vegetarian Softgel(s)DSLD:280070
- Bluebonnet Early Promise PrenatalGentle DHA 200 mgAlgal Oil200 mgper 1 Vegetarian Softgel(s)DSLD:280071
- Bluebonnet Intimate EssentialsFor Her Fertility SupportAlgal Oil50 mgper 1 Capsule(s)DSLD:315069
- Bluebonnet Targeted ChoiceEyeCare25 mgper 2 Capsule(s)DSLD:314968
- Bluebonnet Targeted ChoiceEyeCare25 mgper 2 Capsule(s)DSLD:316445
- BocaGreenMDDHAAlgal Oil · DHA (Form: from Algal Oil) (Alt. Name: Docosahexaenoic Acid)300 mgper 1 Softgel(s)DSLD:43221
- BocaGreenMDPrena1 With QuatrefolicAlgal Oil · DHA (Form: from Algal Oil) (Alt. Name: Docosahexaenoic Acid)200 mgper 1 Softgel(s)DSLD:43222
- BonGeo PharmaceuticalsTendera-OB Prenatal Multivitamin + DHAFish Oil · Omega-3 Fish Oil205 mgper 1 Softgel(s)DSLD:263450
- BrainStrongAdultAlgal Oil · DHA (Form: from Algal Oil) (Alt. Name: Docosahexaenoic Acid)900 mgper 3 Softgel(s)DSLD:60817
- BrainStrongAdultAlgal Oil · DHA (Form: from Algal Oil) (Alt. Name: Docosahexaenoic Acid)900 mgper 3 Softgel(s)DSLD:60818
- Bright BrainChill + Relaxomega 350 mgper 1 Capsule(s)DSLD:318241
- BronsonLife's DHA 200 mgDocosahexaenoic Acid Ethyl Ester · As ethyl esters200 mgper 1 Softgel(s)DSLD:317329
- Bronson LaboratoriesDHA 100 mg100 mgper 1 Softgel(s)DSLD:45725
- Bronson LaboratoriesKrill Oil 500 mg90 mgper 2 Softgel(s)DSLD:8247
- Bronson LaboratoriesOCU-V+18.75 mgper 1 Capsule(s)DSLD:25432
- Bronson LaboratoriesPre & Post-Natal DHA 200 mg200 mgper 1 Softgel(s)DSLD:45484
- BulkSupplements.comMultivitamins 1000 mg Softgels100 mgper 1 Softgel(s)DSLD:312978
- BulkSupplements.comMultivitamins for Men - with Fish Oil Softgels100 mgper 1 Softgel(s)DSLD:312979
- BulkSupplements.comMultivitamins for Men - with Fish Oil Softgels100 mgper 1 Softgel(s)DSLD:314919
- BulkSupplements.comMultivitamins for Men - with Fish Oil Softgels 1000 mg100 mcgper 1 Softgel(s)DSLD:329942
- BulkSupplements.comMultivitamins for Women - with Fish Oil Softgels100 mgper 1 Softgel(s)DSLD:312980
- BulkSupplements.comMultivitamins For Women - with Fish Oil Softgels 1000 mg100 mgper 1 Softgel(s)DSLD:313514
- BulkSupplements.comMultivitamins Softgels100 mgper 1 Softgel(s)DSLD:294795
- BulkSupplements.comMultivitamins Softgels100 mgper 1 Softgel(s)DSLD:294796
- BulkSupplements.comMultivitamins with Fish Oil Softgels 1000 mg100 mgper 1 Softgel(s)DSLD:329778
- Buried Treasure Liquid NutrientsJoint Ease + Plus Pomegranate/Raspberry Flavor100 mgper 30 mLDSLD:250686
- Burton NutritionUltimate Men's Daily PackFish Oil100 mgper 1 Packet(s)DSLD:306046
- California Academy of HealthPure Premium Antarctic Krill Oil 500 mg75 mgper 2 Softgel(s)DSLD:206422
- California Gold NutritionDHA 700 Pharmaceutical Grade Fish Oil 1000 mgDHA as TG700 mgper 1 Softgel(s)DSLD:299610
- Cardiovascular ResearchNeuromins DHA100 mgper 1 Softgel(s)DSLD:22958
- Cardiovascular ResearchNeuromins DHA 100 mg100 mgper 1 Softgel(s)DSLD:304414
- CarlsonAble EyesFish Oil · DHA (Form: from Fish Oil, reported as Triglycerides) (Alt. Name: Docosahexaenoic Acid)100 mgper 1 Softgel(s)DSLD:209266
- CarlsonAble EyesFish Oil · DHA (Form: from Fish Oil, reported as Triglycerides) (Alt. Name: Docosahexaenoic Acid)100 mgper 1 Softgel(s)DSLD:209269
- CarlsonAble EyesFish Oil · DHA (Form: from Fish Oil, reported as Triglycerides) (Alt. Name: Docosahexaenoic Acid)100 mgper 1 Softgel(s)DSLD:216293
- CarlsonAble EyesFish Oil · DHA (Form: from Fish Oil, reported as Triglycerides) (Alt. Name: Docosahexaenoic Acid)100 mgper 1 Softgel(s)DSLD:216295
- CarlsonKid's Norwegian Cod Liver Oil Natural Lemon Flavorreported as triglycerides250 mgper 2.5 mLDSLD:337525
- CarlsonOlive Your Heart Basil FlavorDHA (Form: reported as Triglycerides) (Alt. Name: Docosahexaenoic Acid)900 mgper 15 mLDSLD:216674
- CarWin Pharmaceutical AssociatesTriStart DHA200 mgper 1 Softgel(s)DSLD:279283
- CATALOBaby's Algea Omega-3 Drops432 mgper 0.5 mLDSLD:320578
- CATALOBaby's Vegetarian DHA FormulaDocosahexaenoic Acid · Natural Vegetarian3,000 mgper 500 mgDSLD:303015
- CATALOChildren's DHA Formulaamount not statedper 1 Chewable Softgel(s)DSLD:303027
- CATALOChildren's Vegetarian DHA FormulaDocosahexaenoic Acid · Natural Vegetarian3,000 mgper 500 mgDSLD:303035
- CentrumCentrum Specialist Prenatal200 mgper 1 Tablet(s)DSLD:19028
- ChildLife EssentialsAlgae DHA Natural Berry FlavorAlgae100 mgper 1 Softgel(s)DSLD:327003
- ChildLife EssentialsOmega-3 DHA + Choline SoftChew Gummies Natural Passion Fruit Flavor250 mgper 1 Tablet(s)DSLD:327007
- ChildLife EssentialsPure Arctic Cod Liver Oil Natural Strawberry Flavor1,100 mgper 2.5 mLDSLD:241499
- Cognetix LabsProvasil5 mgper 1 Tablet(s)DSLD:239432
- Cognetix LabsProvasilFish Oil5 mgper 1 Tablet(s)DSLD:274326
- CoromegaDHA Algal Oil Orange FlavorAlgal Oil500 mgper 2.5 Gram(s)DSLD:296863
- Corr-Jensen LabsAb CutsDHA Oil 70%70 mgper 2 Softgel(s)DSLD:2292
- Country LifeBaby Care Prenatal Omega 3-6-9Fish Oil Concentrate · DHA (Form: from Fish Oil concentrate) (Alt. Name: Docosahexaenoic Acid) Note: Omega 3400 mgper 2 Softgel(s)DSLD:182476
- Country LifeOmega 3 MoodFish Oil Concentrate · Docosahexaenoic Acid Note: from fish oil concentrate - sardine, anchovy150 mgper 2 Softgel(s)DSLD:1609
- Covalent MedicalFocus Support1.5 mgper 1 Tablet(s)DSLD:52852
- Covalent MedicalFocus Support1.5 mgper 1 Tablet(s)DSLD:52872
- Culturelle BabyStrong BeginningAlgal Oil70 mgper 0.5 mLDSLD:250619
- Custom Health CentersOmega III288 mgper 1 Softgel(s)DSLD:272714
- Daily HealthOmega 8060 Natural Lemon Flavored576 mgper 2 Softgel(s)DSLD:248017
- Daily HealthOmega 8060 Natural Lemon Flavored576 mgper 2 Softgel(s)DSLD:248082
- DCDHA 100 mgFish Oil · DHA (Alt. Name: Docosahexaenoic Acid) Note: from Fish Oil100 mgper 1 Softgel(s)DSLD:244548
- DCDHA 100 mgFish Oil100 mgper 1 Softgel(s)DSLD:265703
- DCDHA 100 mgFish Oil100 mgper 1 Softgel(s)DSLD:265749
- DEVANon-Fish Vegan Omega-3 DHA200 mgper 1 Softgel(s)DSLD:12924
- Doctor GilmoreHeart Smart Fish Oil Softgels300 mgper 1 Softgel(s)DSLD:182027
- Doctor's BestPhosphatidyl Serine Plus DHAAlgae · DHA (Form: Omega-3 from Algae of Schizochytrium sp.) (Alt. Name: Docosahexaenoic Acid)100 mgper 1 Veggie Softgel(s)DSLD:82325
- Doctor's BestPrenatal EssentialsAlgal (Schizochytrium sp.) Oil250 mgper 4 Veggie Softgel(s)DSLD:271093
- Doctor's BestPurely Prenatal DHA 200 mgVegetable Oil · DHA (Form: as Vegetable Oil (Form: from Algae (Form: of Schizochytrium sp. Genus: Schizochytrium Species: sp.))) (Alt. Name: Docosahexaenoic Acid) Note: Omega-3400 mgper 2 Veggie Softgel(s)DSLD:82381
- Doctor's BestVegan DHA from Algae 200 mgfrom Algae of Schizochytrium sp.200 mgper 1 Veggie Capsule(s)DSLD:302713
- dotFITSuper Omega-3240 mgper 1 Softgel(s)DSLD:12984
- Douglas LaboratoriesADDtendNeuromins · DHA (Form: as Neuromins) (Alt. Name: Docosahexaenoic acid)84 mgper 6 Capsule(s)DSLD:10334
- Douglas LaboratoriesCardiovascular Health Pack200 mgper 1 Packet(s)DSLD:9599
- Douglas LaboratoriesDiabet Support Pack340 mgper 1 Packet(s)DSLD:28174
- Douglas LaboratoriesDiabet-Support Pack340 mgper 1 Packet(s)DSLD:9619
- Douglas LaboratoriesEssential-4 Nutrition Pack340 mgper 1 Packet(s)DSLD:10038
- Douglas LaboratoriesLiquid DHA315 mgper 1 mLDSLD:26907
- Douglas LaboratoriesMetabolic Management Pack340 mgper 1 Packet(s)DSLD:9593
- Douglas LaboratoriesMetabolic Rejuvenation Week 4 Renew170 mgper 1 PackDSLD:261764
- Douglas LaboratoriesNeuromins Algae Source DHAOmega-3 Fatty Acids (Form: as Docosahexaenoic Acid (Alt. Name: DHA))100 mgper 1 Softgel(s)DSLD:10976
- Douglas LaboratoriesNeuroToneMicroalgae, Powder · Docosahexaenoic Acid (Form: from Microalgae powder) (Alt. Name: DHA)42 mgper 4 Tablet(s)DSLD:261489
- Douglas LaboratoriesSenior Men's Pack340 mgper 1 Packet(s)DSLD:9601
- Douglas LaboratoriesUltra Cardio Support Pack340 mgper 1 Packet(s)DSLD:10045
- Douglas LaboratoriesUltra Cardio Support Pack340 mgper 1 Packet(s)DSLD:27277
- Douglas LaboratoriesUltra Preventive V Plus Chel200 mgper 1 Packet(s)DSLD:9714
- Douglas LaboratoriesWeek Four: Renew170 mgper 1 Packet(s)DSLD:231039
- Douglas LaboratoriesWeek Four: Renew340 mgper 2 Packet(s)DSLD:63562
- Douglas LaboratoriesWeek Four: Repair340 mgper 2 Packet(s)DSLD:6220
- Dr. BergCod Liver Oil Capsules50 mgper 3 Capsule(s)DSLD:316054
- Dr. Clark StoreOmega-3 1000 mg172 mgper 1 Softgel(s)DSLD:220015
- Dr. LaMar's ProductsOmega3420 mgper 2 Capsule(s)DSLD:180401
- Dr. SinatraOmega Q Plus 100350 mgper 2 Softgel(s)DSLD:239716
- Dr. Stan GubermanUltimate Joint Repair Platinumamount not statedper 4 Capsule(s)DSLD:33067
- Dr. Stan GubermanUltimate Omega240 mgper 1 Softgel(s)DSLD:33066
- Dr. TobiasOptimum Omega 3 Fish Oil Triple Strength600 mgper 2 Softgel(s)DSLD:73062
- Elevation HealthKrill Oil60 mgper 1 Gelcap(s)DSLD:37474
- Endo-met LaboratoriesEPA-DHA90 mgper 1 Softgel(s)DSLD:229075
- Endo-met LaboratoriesEPA-DHA90 mgper 1 Softgel(s)DSLD:229079
- Esmond Natural180/120 Fish Oil 1000 mg120 mgper 1 Softgel(s)DSLD:178602
- EstrovenStay SharpAlgal Oil400 mgper 2 Softgel(s)DSLD:278648
- Evlution NutritionFish Oil 1250 mg300 mgper 1 Softgel(s)DSLD:239648
- Evlution NutritionOmega-3 Fish Oil 1250 mg300 mgper 1 Softgel(s)DSLD:326405
- Exeltis USADHA Softgel CapsuleAlgal Oil, Natural250 mgper 1 Softgel Capsule(s)DSLD:304794
- Finest NaturalFish Oil Mini-Gels Regular Strength 600 mg108 mgper 1 Softgel(s)DSLD:25940
- Finest NaturalFish Oil Triple Strength 1400 mg253 mgper 1 Softgel(s)DSLD:13190
- Finest NaturalMen's 50+ AdvancedDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-316 mgper 1 Capsule(s)DSLD:13254
- Finest NutritionCod Liver Oil 415 mg36 mgper 1 Softgel(s)DSLD:207018
- Finest NutritionDHA 900 mgAlgal Microalgae Oil900 mgper 1 Softgel(s)DSLD:273795
- Finest NutritionDouble Strength Fish Oil 1200 mgDHA Note: Omega Fatty Acids216 mgper 1 Softgel(s)DSLD:207283
- Finest NutritionFish Oil + D3216 mgper 1 Softgel(s)DSLD:65365
- FitLineGeneration 50+113 mgper 5 Gram(s)DSLD:321592
- FloraDHA Vegetarian Algae500 mgper 2 Capsule(s)DSLD:265450
- Fresh NutritionFish OilOmega-3 DHA (Alt. Name: Docosahexaenoic Acid)120 mgper 2 Softgel Capsule(s)DSLD:241928
- Garden of Life BabyPlant DHA Liquidtriglyceride form600 mgper 0.5 mLDSLD:321372
- Garden of Life Dr. FormulatedPrenatal Multi + DHADHA (Form: Triglyceride form) (Alt. Name: Docosahexaenoic Acid)400 mgper 1 Softgel(s)DSLD:242666
- Gaspari NutritionOmega-3 2400 mgOmega-3 Docosahexaenoic Acid (Alt. Name: DHA)720 mgper 1 Softgel(s)DSLD:223186
- Genestra BrandsSuper EFA Liquid Natural Orange Flavor725 mgper 2.5 mLDSLD:176640
- GesticareDHA CapsuleAlgal Oil · Docosahexaenoic Acid (Form: from Algal Oil) (Alt. Name: DHA)250 mgper 1 Gelatin Capsule(s)DSLD:43186
- GNCCod Liver Oil100 mgper 1 Softgel Capsule(s)DSLD:328783
- GNCDHA 600omega-3600 mgper 1 Softgel Capsule(s)DSLD:305831
- GNCTriple Strength Fish OilDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3360 mgper 1 Yellow Softgel Capsule(s)DSLD:44713
- GNC Beyond RawTriple Strength Fish OilDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3360 mgper 1 Yellow Softgel Capsule(s)DSLD:63775
- GNC Mega MenConcentrated Mini Fish OilDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3144 mgper 1 Yellow Softgel Capsule(s)DSLD:27472
- GNC Mega MenDouble Strength Fish OilDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3240 mgper 1 Light Yellow Softgel Capsule(s)DSLD:33551
- GNC Mega MenDouble Strength Fish OilDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3240 mgper 1 Softgel(s)DSLD:3554
- GNC Mega MenDouble Strength Fish OilDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3240 mgper 1 Softgel(s)DSLD:5893
- GNC Mega MenDouble Strength Fish OilDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega 3240 mgper 1 Light Yellow Softgel Capsule(s)DSLD:66736
- GNC Mega MenFish Oil with CoQ-10DHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3240 mgper 1 Softgel(s)DSLD:15716
- GNC Mega MenFish Oil with CoQ-10240 mgper 1 Green Softgel Capsule(s)DSLD:33634
- GNC Mega MenHeart & Eye HealthDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3360 mgper 1 Softgel(s)DSLD:220279
- GNC Mega MenHigh Potency Fish OilDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3360 mgper 1 Softgel(s)DSLD:219870
- GNC Mega MenMemoralFish Oil · DHA (Form: as Fish Body Oil) (Alt. Name: Docosaehexaenoic Acid, Omega 3)75 mgper 1 Softgel(s)DSLD:15717
- GNC Mega MenMemorallFish Oil · DHA (Form: as Fish Body Oil) (Alt. Name: Docosahexaenoic Acid) Note: Omega-375 mgper 1 Dark Brown Softgel Capsule(s)DSLD:33652
- GNC Mega MenTriple Strength Fish oilDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3360 mgper 1 Amber Softgel(s)DSLD:19430
- GNC Mega MenTriple Strength Fish OilDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3253 mgper 1 Softgel(s)DSLD:3560
- GNC MilestonesConcentrated Mini Fish OilDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3144 mgper 1 Yellow Softgel Capsule(s)DSLD:65759
- GNC MilestonesConcentrated Mini Fish OilDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3144 mgper 1 Yellow Softgel Capsule(s)DSLD:65775
- GNC Preventive NutritionBlood Pressure FormulaDHA Note: Omega-3140 mgper 2 Softgel(s)DSLD:1634
- GNC Preventive NutritionEye Health FormulaFish Oil · fish body200 mgper 2 Softgel Capsule(s)DSLD:304446
- GNC Preventive NutritionFish Oil With PolysterolsDocosahexaenoic Acid Note: Omega-3126.5 mgper 1 Softgel(s)DSLD:3534
- GNC Preventive NutritionMemorallFish Oil · DHA (Form: as Fish Body Oil) (Alt. Name: Docosahexaenoic Acid)150 mgper 2 Softgel(s)DSLD:1837
- GNC Preventive NutritionMulti-OilDHA - omega-3 (Alt. Name: Docosahexaenoic Acid)120 mgper 3 Soft Gel Capsule(s)DSLD:1838
- GNC Preventive NutritionTriple Strength Fish OilDHA Note: Omega-3253 mgper 1 Softgel(s)DSLD:3519
- GNC Pro Performance AMPTriple Strength Fish OilDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3253 mgper 1 Softgel Capsule(s)DSLD:45113
- GNC SelectFish Oil100 mgper 1 Softgel(s)DSLD:313698
- GNC SelectOmega 3-6-9 LemonOmega-3 Fatty Acids120 mgper 3 Softgel(s)DSLD:313699
- GNC Total LeanPremium CLA 3-6-9Fish Oil Concentrate · DHA (Form: from Fish Oil concentrate) (Alt. Name: Docosahexaenoic Acid) Note: Omega 358 mgper 2 Softgel(s)DSLD:213499
- GNC Total LeanPremium CLA ComplexFish Oil · DHA (Form: from Fish Body Oil, Omega-3) (Alt. Name: Docosahexaenoic Acid)58 mgper 2 Softgel(s)DSLD:27243
- GNC Total Lean AdvancedPremium CLA 3-6-9Fish Oil · DHA (Form: from Fish Oil) (Alt. Name: Docosahexaenoic Acid) Note: Omega-358 mgper 2 Softgel(s)DSLD:74477
- GNC Triple StrengthFish OilDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3253 mgper 1 Softgel(s)DSLD:1024
- GNC Triple StrengthFish OilDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3253 mgper 1 Softgel(s)DSLD:219248
- GNC Triple StrengthFish Oil + Vitamin D-3DHA (Alt. Name: Eicosapentaenoic Acid) Note: Omega-3 DHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3253 mgper 1 Softgel(s)DSLD:830
- GNC Triple StrengthFish Oil +Co Q-10DHA Note: Omega-3253 mgper 1 Softgel(s)DSLD:831
- GNC Triple StrengthFish Oil +KrillDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3253 mgper 2 Softgel(s)DSLD:1073
- GNC Triple StrengthFish Oil +ResveratrolDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3253 mgper 1 Softgel(s)DSLD:1071
- GNC Triple StrengthFish Oil SportDHA Note: Omega-3253 mgper 2 Softgel(s)DSLD:1651
- GNC Triple StrengthOmega ComplexDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3253 mgper 3 Softgel(s)DSLD:1050
- GNC Ultra Mega GreenOmega ComplexDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-384.4 mgper 1 Softgel(s)DSLD:11609
- GNC Women'sAlgae-Based DHA 200Marine Microalgae Oil · DHA (Form: as Marine Microalgae Oil) (Alt. Name: Docosahexaenoic Acid)200 mgper 1 Capsule(s)DSLD:214885
- GNC Women'sFish Body OilDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3360 mgper 1 Amber Softgel Capsule(s)DSLD:243671
- GNC Women'sMultivitamin Prenatal Plus DHA & IronFish Oil · DHA (Form: from Fish Body Oil) (Alt. Name: Docosahexaenoic Acid)500 mgper 3 Softgel(s)DSLD:229141
- GNC Women'sPrenatal DHAMarine Algae Oil · DHA (Form: from Marine Algae Oil Genus: Schizochytrium Species: Sp.)300 mgper 1 Softgel Capsule(s)DSLD:27245
- GNC Women'sPrenatal Formula With DHA500 mgper 3 Softgel Capsule(s)DSLD:75159
- GNC Women'sPrenatal With DHA500 mgper 3 Softgel Capsule(s)DSLD:81932
- GNC Women's Ultra MegaConcentrated Fish OilDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3144 mgper 1 Yellow Softgel Capsule(s)DSLD:42241
- GNC Women's Ultra MegaConcentrated Mini Fish OilDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3144 mgper 1 Yellow Softgel Capsule(s)DSLD:33540
- GNC Women's Ultra MegaDouble Strength Fish OilDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3240 mgper 1 Yellow Softgel Capsule(s)DSLD:83088
- GNC Women's Ultra MegaFish Oil With CoQ10DHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3240 mgper 1 Green Softgel Capsule(s)DSLD:33505
- GNC Women's Ultra MegaHeart & Eye HealthDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega 3360 mgper 1 Amber Softgel(s)DSLD:69499
- GNC Women's Ultra MegaMemorallFish Oil · DHA (Form: as Fish Body Oil) (Alt. Name: Docosahexaenoic Acid) Note: Omega-375 mgper 1 Dark Brown Softgel Capsule(s)DSLD:33514
- GNC Women's Ultra MegaTriple Strength Fish OilDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3360 mgper 1 Capsule(s)DSLD:19466
- GNC Women's Ultra MegaTriple Strength Fish OilDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3253 mgper 1 Softgel(s)DSLD:5895
- Gottfried InstituteHormone Balancing EssentialsFish Oil · DHA (Form: from Fish Oil) (Alt. Name: Docosahexaenoic Acid)200 mgper 1 Packet(s)DSLD:45504
- Greens First FemalePrenatal with Vegan DHA plus ProbioticsDocosahexaenoic Acid250 mgper 3 Capsule(s)DSLD:312851
- Guardian HealthKids Vita Plus Natural Orange Flavor0.5 mgper 1 Tablet(s)DSLD:299124
- HBC ProtocolsOmega Complex120 mgper 3 Softgel(s)DSLD:74974
- Health From The SunDHA From Algae OilMicroalgae Oil · Docosahexaenoic Acid (Form: from vegan Microalgae Oil) (Alt. Name: DHA)200 mgper 1 Softgel(s)DSLD:47579
- Health From The SunEye FormulaFish210 mgper 3 Capsule(s)DSLD:45872
- Health From The SunVegan Omega-3 DHAMarine Microalgae Oil · DHA (Form: From vegan microalgae oil) (Alt. Name: Docosahexaenoic Acid) Note: omega-3200 mgper 1 Vegetarian Softgel(s)DSLD:34359
- HerbadietOmega 3 (DHA + EPA)Standardized to contain min 6% DHA400 mgper 2 Capsule(s)DSLD:257823
- HerbadietOmega 3 (DHA + EPA)Standardized to contain min 6% DHA200 mgper 1 Capsule(s)DSLD:293585
- HerbadietOmega 3 (DHA + EPA) PowderStandardized to contain min 6% DHA200 mgper 500 mgDSLD:293637
- Herbalife NutritionCoQ10 PlusAlgal Oil100 mgper 1 Softgel(s)DSLD:335015
- HerblifeCore ComplexAlgal Oil100 mgper 1 Packet(s)DSLD:335016
- HerbTonicsTriglyceride Form Omega-3 2500 mg Lemon Flavored600 mgper 2 Soft Gel(s)DSLD:287069
- High Performance NutritionN(4)810 mgper 3 Softgel(s)DSLD:271158
- Higher NatureComplete Omegas 3:6:7:9480 mgper 4 Capsule(s)DSLD:228412
- Higher NatureComplete Omegas 3:6:7:9120 mgper 1 Capsule(s)DSLD:240570
- Higher NatureComplete Omegas 3:6:7:9480 mgper 4 Capsule(s)DSLD:245644
- Higher NatureComplete Omegas 3:6:7:9480 mgper 4 Capsule(s)DSLD:245645
- Higher NatureComplete Omegas 3:6:7:9480 mgper 4 Capsule(s)DSLD:245653
- Higher NatureComplete Omegas 3:6:7:9480 mgper 4 Capsule(s)DSLD:41470
- Higher NatureComplete Omegas 3:6:7:9480 mgper 4 Capsule(s)DSLD:41474
- Higher NatureComplete Omegas 3:6:7:9480 mgper 4 Capsule(s)DSLD:41475
- Higher NatureComplete Omegas 3:6:7:9480 mgper 4 Capsule(s)DSLD:41485
- Higher NatureEssential Omegas 3:6:7:9120 mgper 1 Capsule(s)DSLD:42576
- Higher NatureKeep Sharp253 mgper 1 Jelly(s)DSLD:178205
- Higher NatureLemon Fish Oil460 mgper 2.5 mLDSLD:217005
- Higher NatureOmega 3 Fish Oil 1000 mg120 mgper 1 Softgel Capsule(s)DSLD:40716
- Higher NatureOmega 3 Fish Oil 1000 mg120 mgper 1 Softgel Capsule(s)DSLD:40930
- Higher NatureOmega 3 Fish Oil 1000 mg120 mgper 1 Softgel Capsule(s)DSLD:40933
- Higher NatureSuper Potency Fish Oil250 mgper 1 Capsule(s)DSLD:246034
- Higher NatureSuper Potency Fish Oil250 mgper 1 Softgel Capsule(s)DSLD:304553
- Higher NatureVisualeyes25 mgper 1 Capsule(s)DSLD:245906
- Higher NatureVisualeyes25 mgper 1 Capsule(s)DSLD:240563
- Higher NatureVisualeyes25 mgper 1 Capsule(s)DSLD:304558
- Higher Nature KidsSmart Focus Intensely Fruity Flavoured Jellies100 mgper 1 Jelly(s)DSLD:216996
- Highland LaboratoriesMy PrenatalDHA (Alt. Name: Docosahexaenoic Acid) Note: vegetarian90 mgper 4 Capsule(s)DSLD:80016
- HMS NutritionLactation Support10 mgper 2 Capsule(s)DSLD:229872
- HoltraCeuticalsUltra Omega300 mgper 1 Softgel(s)DSLD:19884
- i-HealthDHA SoftgelAlgal Oil · Antioxidants [Tocopherols and Ascorbyl Palmitate]350 mgper 1 DHA Softgel(s)DSLD:182727
- IM8Daily Ultimate Longevity + Healthy AgingAlgae · omega-3 fatty acid200 mgper 1 Capsule(s)DSLD:333263
- Indiana Botanic GardensRed Krill Oil 500 mg22:6 - DHA5 mgper 1 Softgel(s)DSLD:46982
- Innovative Apothecary SolutionsMulti ProAlgae315 mgper 1 Capsule(s)DSLD:263602
- Integrative TherapeuticsVitaline Neuro-Essentials5 mgper 2 Caplet(s)DSLD:24221
- Iron-TekEssential Muscle LipidsFish Oil Concentrate · Docosahexaenoic Acid (Form: from Fish Oil Concentrate (Form: Anchovy, Mackerel, Sardine)) (Alt. Name: DHA)160 mgper 2 Softgel(s)DSLD:2918
- Irwin KidsOmega-3 Citrus-Chews Super Citrus Soft ChewsFish Oil · DHA (Form: from Fish Oil) (Alt. Name: Docosahexaenoic Acid) Note: omega-3 fatty acid42 mgper 1 Soft Chew(s)DSLD:45699
- John Gilmore, MDHeart Smart Fish Oil Softgels300 mgper 1 Softgel(s)DSLD:267848
- JuvenonEssential Omega-3400 mgper 2 Softgel(s)DSLD:261896
- KidzPlayBrainy PlayDHA Note: 18.3 mg118.3 mgper 1 mLDSLD:22250
- KirkmanAll Natural Cod Liver Oil Liquid250 mgper 0.5 Teaspoon(s)DSLD:23981
- KirkmanAll Natural Cod Liver Oil Liquid250 mgper 0.5 Teaspoon(s)DSLD:23986
- KirkmanCod Liver Oil Liquid150 mgper 2.5 mLDSLD:259995
- KirkmanCod Liver Oil Liquid Natural Lemon Lime Flavor150 mgper 2.5 mLDSLD:317718
- Krill Doctor ProfessionalKrill Omega-390 mgper 2 Softgel(s)DSLD:175022
- Lake Avenue NutritionDHA from Marine Algae 200 mgAlgal Oil200 mgper 1 Softgel(s)DSLD:272337
- Leading Edge HealthBrainPillOmega-3 Fish Oil powder · DHA 15%100 mgper 1 Capsule(s)DSLD:280518
- LifeVegetarian Algae DHA200 mgper 1 Vegetarian Softgel(s)DSLD:39528
- Life ExtensionOmega-3 Lemon Whirl422 mgper 1 TbspDSLD:58974
- Life ExtensionOmega-3 Tropical Whirl422 mgper 1 TbspDSLD:58979
- Life ExtensionPrenatal AdvantageAlgae Oil200 mgper 1 Softgel(s)DSLD:328644
- Life ExtensionVegetarian DHAAlgae Oil · DHA (Form: from Algae Oil Genus: Schizochytrium Species: sp.) (Alt. Name: Docosahexaenoic Acid)200 mgper 1 Vegetarian Softgel(s)DSLD:232135
- Life NutritionBaby Algae DHA100 mgper 1 Softgel(s)DSLD:206166
- Life's DHABrainstrong AdultAlgal Oil · DHA Note: docosahexaenoic acid from algal oil900 mgper 3 Softgel(s)DSLD:2493
- Life's DHALife's DHA AdultAlgal Oil · DHA (Form: from Algal Oil) (Alt. Name: Docosahexaenoic Acid)200 mgper 1 Softgel(s)DSLD:242624
- Life's DHALife's DHA KidsAlgal Oil · DHA (Form: from Algal Oil) (Alt. Name: Docosahexaenoic Acid)100 mgper 1 Softgel(s)DSLD:242622
- Life's DHALife's DHA Kids & TeensAlgal Oil · DHA (Form: from Algal Oil) (Alt. Name: Docosahexaenoic Acid)200 mgper 1 Softgel(s)DSLD:242620
- Living FuelSuper Essentials Omegas 3EDA+Fish Oil · DHA (Form: from purified Fish Oils) (Alt. Name: Docosahexanoic Acid) Note: 22:6 Omega 3120 mgper 1 Softgel(s)DSLD:282561
- Martin Avenue PharmacyBrain Health Support With Ginkgo Biloba & Phosphatidyl SerineDHA powder (Alt. Name: docosahexaenoic acid) Note: From Neuromins(TM) a highly purified source of DHA from microalgae.100 mgper 2 Tablet(s)DSLD:18812
- Martin Avenue PharmacyDHA 100 mgMicroalgae Oil · DHA (Form: from microalgae oil) (Alt. Name: docosahexaenoic acid) Note: Neuromins(TM) is a highly-purified source of DHA from microalgae. It is produced under strict quality control conditions and is free of chemical pollutants and toxins.100 mgper 1 Capsule(s)DSLD:19074
- Mary Ruth'sOrganic Women's Multivitamin Liposomal Vanilla PeachAlgal Oil · Omega-3100 mgper 15 Milliliter(s)DSLD:327734
- Mary Ruth'sOrganic Women's Multivitamin Liposomal Vanilla PeachAlgal Oil · Omega-3100 mgper 15 Milliliter(s)DSLD:327735
- Mary Ruth'sTurmeric & DHA Liposomal Orange GingerAlgal Oil · omega-3210 mgper 15 mLDSLD:327736
- Mason NaturalNorwegian Salmon Oil 2000 mg220 mgper 2 Softgel(s)DSLD:244788
- Mason NaturalSugar-Free Prenatal Multivitamin with DHA & ZincAlgae Oil, Powder · DHA (Form: from Algae Oil) (Alt. Name: Docosahexanoic Acid)50 mgper 3 Gummy(ies)DSLD:244892
- Maxi HealthMaxi-Omega-3 Concentrate460 mgper 2 Softgel(s)DSLD:295567
- MeijerOnce Daily Prenatal MultiSchizochytrium sp. Oil · Omega-3200 mgper 1 Softgel(s)DSLD:296587
- Mental RefreshmentKrill Oil 1000 mg130 mgper 2 Capsule(s)DSLD:247641
- MetagenicsMetaKids Nutrition Powder Chocolate Flavor75 mgper 29 Gram(s)DSLD:216415
- MetagenicsMetaKids Nutrition Powder Vanilla Flavor75 mgper 27 Gram(s)DSLD:295766
- MetagenicsPlusOne1 Gram(s)per 1 Packet(s)DSLD:216819
- MetagenicsWellness Essentials Brain HealthDHA (Form: Docosahexaenoic Acid Triglyceride)750 mgper 1 Packet(s)DSLD:211103
- Method PharmaceuticalsDothelle DHA Softgels156 mgper 1 Capsule(s)DSLD:263294
- Mission Pharmacal CitraNatalCitraNatal 90 DHA 300 mg DHA Soft GelAlgal Oil · Docosahexaenoic Acid (Form: from 750 mg 40% Algal Oil) (Alt. Name: DHA)300 mgper 1 Softgel(s)DSLD:240145
- Mission Pharmacal CitraNatalCitranatal 90 DHA Gelatin Capsule300 mgper 1 Gelatin Capsule(s)DSLD:45458
- Mission Pharmacal CitraNatalCitraNatal 90 DHA Gelatin Capsule300 mgper 1 Gelatin Capsule(s)DSLD:63755
- Mission Pharmacal CitraNatalCitranatal 90 DHA Soft GelAlgal Oil · Docosahexaenoic Acid (Form: from 750 mg 40% Algal Oil) (Alt. Name: DHA)300 mgper 1 Softgel(s)DSLD:215339
- Mission Pharmacal CitraNatalCitraNatal Assure 300 mg DHA Soft GelAlgal Oil · Docosahexaenoic Acid (Form: from 750 mg 40% Algal Oil) (Alt. Name: DHA)300 mgper 1 Softgel(s)DSLD:206922
- Mission Pharmacal CitraNatalCitraNatal Assure DHA Capsule300 mgper 1 Capsule(s)DSLD:37182
- Mission Pharmacal CitraNatalCitraNatal Assure DHA Gelatin CapsuleDocosahexaenoic Acid (Alt. Name: DHA) Note: 40% from300 mgper 1 Capsule(s)DSLD:63989
- Mission Pharmacal CitraNatalCitraNatal Assure DHA Soft GelAlgal Oil · Docosahexaenoic Acid (Form: from 750 mg 40% Algal Oil) (Alt. Name: DHA)300 mgper 1 Softgel(s)DSLD:215277
- Mission Pharmacal CitraNatalCitraNatal Assure DHA Soft Gel300 mgper 1 Softgel(s)DSLD:304787
- Mission Pharmacal CitraNatalCitraNatal DHA Gelatin Capsule250 mgper 1 Gelatin Capsule(s)DSLD:45465
- Mission Pharmacal CitraNatalCitraNatal DHA Soft GelAlgal Oil · Docosahexaenoic Acid (Form: from 750 mg 40% Algal Oil) (Alt. Name: DHA)300 mgper 1 Softgel(s)DSLD:241671
- Mission Pharmacal CitraNatalCitraNatal Essence DHA Soft GelAlgal Oil · Docosahexaenoic Acid (Form: from 750 mg 40% Algal Oil) (Alt. Name: DHA)300 mgper 1 Softgel(s)DSLD:232435
- Mission Pharmacal CitraNatalCitraNatal Harmony250 mgper 1 Capsule(s)DSLD:12884
- Mission Pharmacal CitraNatalCitraNatal HarmonyAlgal Oil · Docosahexaenoic Acid (Form: from 650 mg 40% Algal Oil) (Alt. Name: DHA)260 mgper 1 Soft Gel(s)DSLD:215317
- Mission Pharmacal CitraNatalCitraNatal HarmonyDocosahexaenoic Acid (Alt. Name: DHA) Note: 40% from260 mgper 1 Capsule(s)DSLD:43173
- Mission Pharmacal CitraNatalCitraNatal MedleyAlgal Oil · Docosahexaenoic Acid (Form: from 377 mg 53% Algal Oil) (Alt. Name: DHA)200 mgper 1 Softgel(s)DSLD:205154
- MN Morphogen NutritionNutrigen Cranberry AppleAlgae · Vegan Algae Source Providing 250mg DHA2,500 mgper 27 Gram(s)DSLD:261187
- Morphogen NutritionNutrigen Pineapple PunchDocosahexaenoic Acid (Form: providing 250 mg DHA) (Alt. Name: DHA) Note: (vegan algae source) (10%)2,500 mgper 24.5 Gram(s)DSLD:212764
- Mountain Meadow HerbsKrill Oil 1200 mg80 mgper 1 Softgel(s)DSLD:267493
- MRI PerformanceOmega 3omega-3253 mgper 1 Softgel(s)DSLD:313484
- MRMFresh Omega Extra Virgin Norwegian Salmon Oil60 mgper 1 Fish softgel(s)DSLD:178447
- MusclePharmFish Oil300 mgper 1 Soft Gel(s)DSLD:17995
- MuscleSportLipoSlim for HerDeep Sea Cold Water Fish Oil Complexamount not statedper 2 Softgel(s)DSLD:256919
- Natural Cell SupplementsOmegaActiv288 mgper 1 Softgel(s)DSLD:317955
- Natural ClinicianClinical CognitionTuna · DHA (Form: Docosahexaenoic Acid (Form: from tuna fish))30 mgper 1 Capsule(s)DSLD:18615
- Natural ClinicianClinical EPA/DHA ForteDHA (Alt. Name: Docosahexaenoic Acid) Note: Targeted Delivery for enhanced absorption and bioactivity.400 mgper 1 Softgel(s)DSLD:18623
- Natural Health Improvement CenterEnteric Coated Fish Oil340 mgper 2 Softgel(s)DSLD:71195
- Natural NutraKrill Oil37.5 mgper 1 Softgel(s)DSLD:246973
- Nature's BountyHeart Health Support Packamount not statedper 1 Packet(s)DSLD:3788
- Nature's BountyPrenatal Multi Healthy MomAlgal · Docosahexaenoic Acid (Form: from DHA rich oil derived from a plant based algae Schizochytrium sp. Genus: Schizochytrium Species: sp.) (Alt. Name: DHA)200 mgper 2 Softgel(s)DSLD:240159
- Nature's Bounty Optimal SolutionsHealthy Mom Prenatal MultiAlgal · Docosahexaenoic Acid (Form: from DHA rich oil derived from a plant based algae Schizochytrium sp. Genus: Schizochytrium Species: sp.) (Alt. Name: DHA)200 ngper 2 Softgel(s)DSLD:308222
- Nature's Bounty Optimal SolutionsVegetarian DHA 200 mgAlgal · Docosahexaenoic Acid (Form: from DHA rich oil derived from a plant based algae Schizochytrium sp. Genus: Schizochytrium Species: sp.) (Alt. Name: DHA)200 mgper 1 Softgel(s)DSLD:29296
- Nature's CraftKids Multivitamin Drops Orange FlavorAlgae50 mgper 1 mLDSLD:296785
- Nature's LifeOmega 3 EFA Complex360 mgper 3 Softgel(s)DSLD:47347
- Nature's NutraVegetarian DHA for KidsAlgal Oil100 mgper 1 mLDSLD:318826
- Nature's WayAlive! Complete Premium Prenatal MultivitaminAlgal Oil200 mgper 2 Softgel(s)DSLD:304619
- Nature's WayAlive! Premium Prenatal Gummies Strawberry & Lemon FlavoredAlgal Oil75 mgper 3 Gummy(ies)DSLD:332156
- Nature's WayAlive! Prenatal Multivitamin GummyAlgal Oil50 mgper 2 Gummy(ies)DSLD:327866
- Nature's WayCompletia Prenatal Multi-Vitamin25 mgper 2 Tablet(s)DSLD:230198
- Nature's WayCompletia Prenatal Multi-VitaminTuna25 mgper 2 Tablet(s)DSLD:56163
- Nature's WayCompletia Prenatal Multi-VitaminTuna50 mgper 2 Tablet(s)DSLD:66513
- Nature's WayEfaGold NeurominsAlgal Microalgae Oil · Docosahexaenoic Acid (Form: from Algal Microalgae Oil) (Alt. Name: DHA)200 mgper 1 Softgel(s)DSLD:79297
- Nature's WayEfaGold Neuromins 100 mg DHAAlgal Microalgae Oil · Docosahexaenoic Acid (Form: from Algal Microalgae (Schizochytrium spp.) oil Genus: Schizochytrium Species: spp.) (Alt. Name: DHA)100 mgper 1 Softgel(s)DSLD:63622
- Nature's WayNeurominsAlgal Microalgae Oil · Docosahexaenoic Acid (Form: from Algal Microalgae (Schizochytrium spp.) oil Genus: Schizochytrium Species: spp.) (Alt. Name: DHA)100 mgper 1 Softgel(s)DSLD:230015
- Nature's WayNeurominsAlgal Microalgae Oil200 mgper 1 Softgel(s)DSLD:304679
- Natures CraftOmega-3 Fish Oil 1200 mg288 mgper 1 Softgel(s)DSLD:256575
- NatureSmartDisney Monsters University Multi-Vitamin GummiesFish Oil · DHA (Form: from Fish Oil) (Alt. Name: Docosahexaenoic Acid)50 mcgper 1 Gummy(ies)DSLD:71459
- NatureSmartDisney My First Gummies Multi VitaminFish Oil · DHA (Form: from Fish Oil) (Alt. Name: Docosahexaenoic Acid)100 mcgper 2 Gummy(ies)DSLD:12265
- NatureSmartDisney Princess Complete MultiVitaminFish Oil · DHA (Form: from Fish Oil) (Alt. Name: Docosahexaenoic Acid)100 mgper 1 Tablet(s)DSLD:26529
- NatureSmartDisney Tinkerbell Multi-Vitamin GummiesFish Oil · DHA (Form: from Fish Oil) (Alt. Name: Docosahexaenoic Acid)100 mcgper 1 Gummy(ies)DSLD:71425
- NatureSmartGummies MultivitaminFish Oil · DHA (Form: from Fish Oil) (Alt. Name: Docosahexaenoic Acid)100 mcgper 2 Gummie(s)DSLD:26536
- NaturesPlusOmega Krill Oil 600 mg35 mgper 1 Liquid-Filled Capsule(s)DSLD:298566
- NaturesPlusPro Creation Female Fertility Supportfrom Algae of Schizochytrium sp. · vegetarian16 mgper 2 Capsule(s)DSLD:298597
- NatureWiseMultivitamin & Minerals Prenatal CompleteDocosahexaenoic Acid20 mgper 2 Capsule(s)DSLD:327751
- NCBAlaska Deep Sea Fish Oil240 mgper 2 Softgel(s)DSLD:13732
- Nested NaturalsVegan Omega-3Algal Oil250 mgper 1 Vegan Capsule(s)DSLD:286825
- Neurohacker CollectiveQualia MindAlgae · DHA (Form: from Algae) (Alt. Name: Docosahexaenoic Acid)80 mgper 7 Vegetarian Capsule(s)DSLD:258978
- Neurohacker CollectiveQualia MindAlgae80 mgper 7 Vegetarian Capsule(s)DSLD:267666
- Neurohacker CollectiveQualia MindAlgae80 mgper 7 Capsule(s)DSLD:314263
- Neurohacker CollectiveQualia Mind Caffeine FreeAlgae · DHA (Form: from Algae) (Alt. Name: Docosahexaenoic Acid)80 mgper 7 Vegetarian Capsule(s)DSLD:239667
- New AgeFish Oil 2500 mg682 mgper 2 Softgel(s)DSLD:268645
- Noor VitaminsPre & Post Natal DHA + Iron Fruit FlavoredAlgal Oil · Docosahexaenoic Acid (Form: from Algal Oil) (Alt. Name: DHA)75 mgper 3 Gummie(s)DSLD:183318
- Nordic NaturalsChildren's DHA Strawberry255 mgper 2.5 mLDSLD:214259
- Nordic NaturalsChildren's DHA Strawberry255 mgper 2.5 mLDSLD:277314
- North American Herb & SpicePurelyPak95 mgper 7.3 Gram(s)DSLD:270080
- North American Herb & SpicePurelyPak126 mgper 7.3 Gram(s)DSLD:307960
- NOWDouble Strength DHA-500amount not statedper 1 Softgel(s)DSLD:314277
- NOWVegetarian DHA400 mgper 2 Softgel(s)DSLD:36617
- Nutra SportPerformance Omega-3350 mgper 1 Softgel(s)DSLD:319228
- NutraChampsOmega 3 Fish Oil 3,600 mg Natural Lemon Flavor864 mgper 3 Softgel(s)DSLD:228956
- NutraKeyFish Oil 1000 mg120 mgper 1 Softgel(s)DSLD:287400
- Nutri-RichMini Me DHA 100 mgAlgae Oil, Powder · DHA (Form: from Algae Oil) (Alt. Name: Docosahexanoic Acid)100 mgper 1 Softgel(s)DSLD:176524
- Nutri-RichMini Me DHA 100 mgAlgae Oil, Powder · DHA (Form: from Algae Oil) (Alt. Name: Docosahexaenoic Acid)100 mgper 1 Softgel(s)DSLD:214111
- Nutri-RichPrenatal Multi+DHAAlgae Oil, Powder · DHA (Form: from Algae Oil) (Alt. Name: Docosahexanoic Acid)200 mgper 1 Softgel(s)DSLD:176556
- Nutri-RichUltra EPA + DHA 1,000 mg250 mgper 2 Softgel(s)DSLD:176515
- Nutri-RichUltra EPA + DHA 1,000 mg250 mgper 2 Softgel(s)DSLD:214108
- Nutri-WestComplete Hi-Potency Omega-3 LiquidFish · DHA (Form: contains Fish) (Alt. Name: Docosahexaenoic Acid)800 mgper 1 Teaspoon(s)DSLD:27617
- NutriCologySuper Immuno Complex240 mgper 1 Packet(s)DSLD:183928
- NutricostJoint Complex 1490 mg50 mgper 2 Capsule(s)DSLD:77150
- NutriSuppzSuper Krill Oil Complex 500 mg105 mgper 1 Softgel(s)DSLD:268894
- OL Olympian LabsKrill Oil 1000 mg90 mgper 2 Softgel(s)DSLD:326661
- OL Olympian LabsKrill Oil 1000 mg90 mgper 2 Softgel(s)DSLD:326672
- OL Olympian LabsKrill Oil 500 mg45 mgper 1 Softgel(s)DSLD:175745
- OL Olympian LabsNorwegian Salmon Oil240 mgper 3 Softgel(s)DSLD:9738
- OL Olympian LabsPrenatal Complex3 mgper 1 Capsule(s)DSLD:67155
- OmegaWorksDelicious Omega 3 Liquid Formula500 mgper 1 tspDSLD:7686
- OmegaWorksSuper Omega 3200 mgper 1 Softgel(s)DSLD:259729
- OraNothing Fishy Here. Fresh Orange Flavor600 mgper 1 mLDSLD:183945
- Orphic NutritionOmega 3 Fish Oil 2160 mg864 mgper 1 Softgel(s)DSLD:285532
- Ortho Molecular ProductsOrthomega Select DHA580 mgper 1 Softgel Capsule(s)DSLD:174227
- Ortho Molecular ProductsOrthomega Select EPA60 mgper 1 Softgel Capsule(s)DSLD:174221
- Ortho Molecular ProductsPrenatal Complete with DHA580 mgper 3 Capsule(s)DSLD:175696
- PerqueEPA/DHA Guard500 mgper 2 Softgel(s)DSLD:240750
- PerqueEPA/DHA Guard500 mgper 2 Softgel(s)DSLD:240753
- PerqueEPA/DHA Guard Softgels500 mgper 2 Softgel(s)DSLD:18732
- PerqueEPA/DHA Guard Softgels500 mgper 2 Softgel(s)DSLD:18733
- PharmaPure RxPNV OB+DHA Softgel250 mgper 1 Softgel(s)DSLD:37180
- PharmaxBerry Frutol375 mgper 10 mLDSLD:238900
- PharmaxCardol210 mgper 1 tspDSLD:55422
- PharmaxDHA TasteBurst Natural Orange Flavor130 mgper 2 Chewable Soft Gel(s)DSLD:55433
- PharmaxFinest Pure Cod Liver Oil466 mgper 0.5 tspDSLD:55776
- PharmaxFinest Pure Fish Oil725 mgper 0.5 tspDSLD:176136
- PharmaxFinest Pure Fish Oil725 mgper 0.5 tspDSLD:55813
- PharmaxFinest Pure Fish Oil625 mgper 1 tspDSLD:70995
- PharmaxFinest Pure Fish Oil Capules375 mgper 2 Capsule(s)DSLD:55371
- PharmaxFinest Pure Fish Oil Plus CoQ10 Natural Orange Flavor710 mgper 1 tspDSLD:55432
- PharmaxFinest Pure Krill Oil70 mgper 2 Capsule(s)DSLD:55436
- PharmaxFrutol187.5 mgper 1 tspDSLD:55369
- PharmaxFrutol with Full Spectrum Multivitamins172.5 mgper 1 tspDSLD:55787
- PharmaxHigh DHA Berry Frutol600 mgper 2 tspDSLD:55391
- PharmaxHigh DHA Omega-3 Fatty AcidsTuna Oil · Docosahexaenoic acid (Form: provided as Tuna oil) (Alt. Name: DHA)200 mgper 1 Softgel Capsule(s)DSLD:70981
- PharmaxHigh EPA Finest Pure Fish Oil Natural Orange Flavor320 mgper 1 tspDSLD:55431
- PharmaxOmega-3 Fatty Acids265 mgper 1 Capsule(s)DSLD:55838
- PharmaxOmega-3 Fatty Acids265 mgper 1 Capsule(s)DSLD:55888
- PharmaxOmega-3 Fatty Acids265 mgper 1 Capsule(s)DSLD:56157
- PharmaxOmega-3 Fatty Acids265 mgper 1 Softgel(s)DSLD:70941
- PharmaxOmega-3 Fatty Acids265 mgper 1 Softgel(s)DSLD:71006
- Pharmaxa LabsProvasil5 mgper 1 Tablet(s)DSLD:306938
- Physician's StrengthPotentPak126 mgper 7.3 Gram(s)DSLD:268772
- Phyto ParisPhytophanere2 mgper 2 Caplet(s)DSLD:206205
- Pink StorkPrenatal Plus DHA200 mgper 2 Capsule(s)DSLD:216949
- PlexusMegaKids Microbiome Tropical PunchMarine Algae Oil50 mgper 1 Stick(s)DSLD:317543
- PNV Prenatal HealthDHA MiniCaps250 mgper 1 MiniCap(s)DSLD:241348
- Premier Research LabsPremier DHAAlgal Oil200 mgper 1 Softgel(s)DSLD:269251
- Primal HarvestPrimal Omega-3400 mgper 2 Softgel(s)DSLD:277139
- Primal PharmOMEGA288 mgper 1 Softgel(s)DSLD:276404
- Priority One Nutritional SupplementsComplete One Daily5%42 mgper 1 Capsule(s)DSLD:277352
- ProceraOmega-3288 mgper 1 Softgel(s)DSLD:293227
- Progressive Professional from Progressive LaboratoriesBrilliant Vision with Seanol-P100 mgper 3 Vegetable Capsule(s)DSLD:261438
- Progressive Professional from Progressive LaboratoriesEPA-DHA 1000 mg100 mgper 1 Softgel Capsule(s)DSLD:261658
- Pure EncapsulationsDHA Liquid1 Gram(s)per 1 mLDSLD:205211
- Pure EncapsulationsEPA/DHA Vegetarian310 mgper 2 Caplique(R) Capsule(s)DSLD:182879
- Pure EncapsulationsEPA/DHA Vegetarian310 mgper 2 Caplique(R) Capsule(s)DSLD:184456
- Pure Label NutritionKrill Oil 1000 mg40 mgper 2 Capsule(s)DSLD:269590
- Pure OneAlgae Oil350 mgper 1 Softgel(s)DSLD:43285
- Pure OneAlgae Omega-3700 mgper 2 Vegetarian Softgel(s)DSLD:211607
- Pure OneDHAlicious Organic Lemon & Green Tea Flavor720 mgper 1 mLDSLD:202540
- Pure OneDHAlicious Organic Lemon Flavored180 mgper 0.5 mLDSLD:202543
- Pure PrescriptionsPremium Omega-3DHA (Form: as Triglycerides) (Alt. Name: Docosahexaenoic Acid)480 mgper 2 Softgel(s)DSLD:228209
- Puritan's PrideDHA 100 mg100 mgper 1 Softgel(s)DSLD:271068
- Puritan's PrideExtra Strength DHA 500 mg500 mgper 1 Softgel(s)DSLD:286293
- Puritan's PridePrenatal Multivitamin w/DHAAlgae · from DHA rich oil derived from a plant based algae200 mgper 2 Softgel(s)DSLD:286029
- Purity LabsAntarctic Krill Oil80 mgper 2 Softgel(s)DSLD:313927
- QualiaMindAlgae · DHA (Form: from Algae) (Alt. Name: Docosahexaenoic Acid)80 mgper 7 Vegetarian Capsule(s)DSLD:239658
- QualiaMind Caffeine FreeAlgae80 mgper 1 Vegetarian Capsule(s)DSLD:314264
- Quantum Nutrition LabsQuantum Plant DHAAlgal Oil200 mgper 1 Softgel(s)DSLD:302390
- Quantum Nutrition LabsQuantum Plant DHAAlgal Oil200 mgper 1 Softgel(s)DSLD:329032
- Remedys NutritionUltimate Omega-3 Fish Oil82 mgper 1 Vegetarian Capsule(s)DSLD:272190
- Renew LifeSuper Critical Omega240 mgper 1 Softgel(s)DSLD:2345
- Rexall SundownMarvel Heroes GummiesFish Oil · DHA (Form: from Fish Oil) (Alt. Name: Docosahexaenoic Acid)100 mcgper 2 Gummy(ies)DSLD:26206
- Rite Aid PharmacyNatural Fish Oil 1000 mgDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3200 mgper 2 Softgel(s)DSLD:181533
- Rite Aid PharmacyNatural Fish Oil 1000 mgDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3200 mgper 2 Softgel(s)DSLD:239751
- Rite Aid PharmacyOmega 3-6-9 Lemon Natural FlavorDHA (Alt. Name: Docosahexaenoic Acid) Note: Omega-3120 mgper 3 Softgel Capsule(s)DSLD:239828
- Ron Teeguarden NutraceuticalsDHA 100 mgMicroalgae Oil100 mgper 1 Vegetarian Softgel(s)DSLD:316670
- RugbyOmega-3 Krill Oil17 mgper 1 Softgel(s)DSLD:201205
- Salaam NutritionalsOmega 3 Fish Oil600 mgper 2 Softgel(s)DSLD:292292
- Salaam NutritionalsPrenatal140 mgper 4 Gummy(ies)DSLD:247265
- Salaam NutritionalsPrenatal DHA + Folate105 mgper 4 Gummy(ies)DSLD:292290
- Science Natural SupplementsOmega-3X EPA 432 mg/DHA 288 mg288 mgper 1 Softgel(s)DSLD:276468
- SeniorLife HealthOmega 3-6-9 Complete48 mgper 1 Softgel(s)DSLD:256552
- SFHSO3 Super Omega 3 LemonDHA (Alt. Name: Docosahexaenoic Acid) Note: 1025-1075mg1,075 mgper 1 tspDSLD:16320
- SFHSO3 SuperOmega3 LemonDHA (Alt. Name: Docosahexaenoic Acid) Note: 1025-1075mg1,075 mgper 1 tspDSLD:16322
- ShakleeVegan Omega-3Algal400 mgper 2 Softgel(s)DSLD:318625
- SimplySupplementsOmega 3 Fish Oil 1000 mg120 mgper 1 Capsule(s)DSLD:22011
- SimplySupplementsOmegaMax220 mgper 1 Capsule(s)DSLD:22533
- SmarterVitaminsOmega-3 Strawberry Flavored600 mgper 2 Softgel(s)DSLD:243878
- SmartyPantsBaby Multi & DHAAlgae · Omega-350 mgper 1 mLDSLD:266165
- SmartyPantsMen's 50+ FormulaAlgal Oil · omega-3 DHA100 mgper 1 Capsule(s)DSLD:306756
- SmartyPantsMen's 50+ FormulaAlgal Oil · omega-3 DHA100 mgper 1 Capsule(s)DSLD:306757
- SmartyPantsMen's FormulaAlgal Oil · omega-3 DHA100 mgper 1 Capsule(s)DSLD:306758
- SmartyPantsMen's FormulaAlgal Oil · omega-3 DHA100 mgper 1 Capsule(s)DSLD:306759
- SmartyPantsPrenatal FormulaAlgal Oil · omega-3 DHA100 mgper 1 Capsule(s)DSLD:306750
- SmartyPantsPrenatal FormulaAlgal Oil · omega-3 DHA100 mgper 1 Capsule(s)DSLD:306751
- SmartyPantsWomen's 50+ MultiAlgal Oil · omega-3 DHA100 mgper 1 Capsule(s)DSLD:306753
- SmartyPantsWomen's FormulaAlgal Oil · omega-3 DHA100 mgper 1 Capsule(s)DSLD:306755
- SolarayDHA 100 mg Plant SourcedAlgal Oil100 mgper 1 Vegan Softgel(s)DSLD:338304
- SolgarNaturally Sourced Omega-3 Vegetarian DHA 200 mgDocosahexaenoic Acid (Alt. Name: DHA) Note: from200 mgper 1 Softgel(s)DSLD:77225
- SomaLife InternationalOmega-3DHA Note: Min 20%240 mgper 1 Capsule(s)DSLD:33371
- Source NaturalsAttentive DHA 100 mgAlgal Oil · Docosahexaenoic Acid (Form: from Algal Oil (Alt. Name: life'sDHA)) (Alt. Name: DHA)100 mgper 1 Softgel(s)DSLD:214030
- Source NaturalsAttentive DHA 100 mgAlgal Oil · Docosahexaenoic Acid (Form: from Algal Oil (Alt. Name: life'sDHA)) (Alt. Name: DHA)100 mgper 1 Softgel(s)DSLD:273085
- Source NaturalsComplete Essential Fatty AcidsDocosahexaenoic Acid (Alt. Name: DHA) Note: Omega-3192 mgper 3 Softgel(s)DSLD:214196
- Source NaturalsComplete Essential Fatty AcidsDocosahexaenoic Acid (Alt. Name: DHA) Note: Omega-3192 mgper 3 Softgel(s)DSLD:214207
- Source NaturalsNeuromins DHA 100 mgAlgal Oil · Docosahexaenoic Acid (Form: from Algal Oil (Alt. Name: life'sDHA)) (Alt. Name: DHA)200 mgper 1 Softgel(s)DSLD:211644
- Source NaturalsNeuromins DHA 200 mgAlgal Oil · Docosahexaenoic Acid (Form: from Algal Oil) (Alt. Name: DHA, life'sDHA)600 mgper 3 Softgel(s)DSLD:213589
- Source NaturalsNeuromins DHA 200 mgAlgal Oil · Docosahexaenoic Acid (Form: from Algal Oil) (Alt. Name: DHA, life'sDHA)600 mgper 3 Softgel(s)DSLD:213604
- Source NaturalsNeuromins DHA 200 mgAlgal Oil · Docosahexaenoic Acid (Form: from Algal Oil) (Alt. Name: DHA, life'sDHA)600 mgper 3 Softgel(s)DSLD:272854
- Source NaturalsOmega 3-6-9Docosahexaenoic Acid (Alt. Name: DHA) Note: omega-3192 mgper 3 Softgel(s)DSLD:273928
- Source NaturalsOmega 3-6-9Omega-3192 mgper 3 Softgel(s)DSLD:275607
- Source NaturalsOmegaEPA Fish Oil 120 mgper 1 Softgel(s)DSLD:275432
- Source NaturalsVegan Omega-3s 300 mg360 mgper 1 Softgel(s)DSLD:273971
- Source NaturalsVegan Omega-3s 300 mg360 mgper 1 Softgel(s)DSLD:273974
- Source NaturalsVegan Omega-3s 300 mg360 mgper 1 Softgel(s)DSLD:78805
- Source NaturalsVegan True Non-Fish Omega-3s 300 mg360 mgper 1 Softgel(s)DSLD:274005
- Source NaturalsVegetarian DHA 200 mgAlgal Oil · Docosahexaenoic Acid (Form: from Algal Oil) (Alt. Name: life'sDHA)600 mgper 1 Vegetarian Softgel(s)DSLD:78941
- Source OilAlgae Omega-32,000 mgper 2 mLDSLD:211605
- Source OilAlgae Omega-3 Organic Lemon Flavor2,000 mgper 0.5 Teaspoon(s)DSLD:211612
- SP Standard ProcessCalamari Omega-3 Liquid800 mgper 5 mLDSLD:256403
- SP Standard ProcessCod Liver Oil300 mgper 3 Softgel(s)DSLD:256486
- SP Standard ProcessCod Liver Oil300 mgper 3 Softgel(s)DSLD:340155
- SP Standard ProcessGeneral Health Daily Fundamentals300 mgper 1 Pack(s)DSLD:292105
- SP Standard ProcessTuna Omega-3 Chewable240 mgper 2 Softgel(s)DSLD:340291
- Spring ValleyAdult Gummy Omega-3 Complex with EPA/DHA50 mgper 2 Gummie(s)DSLD:73430
- Spring ValleyAlgal-900 DHA450 mgper 1 Softgel(s)DSLD:13039
- Spring ValleyDHA 200 mgAlgal Docosahexaenoic Acid200 mgper 1 Softgel(s)DSLD:26458
- SundownMarvel The Amazing Spider-Man CompleteFish Oil · DHA (Form: from Fish Oil) (Alt. Name: Docosahexaenoic Acid)50 mcgper 0.5 Tablet(s)DSLD:197373
- Sundown NaturalsVitamin EssentialsAlgal · Docosahexaenoic Acid (Form: from DHA rich oil derived from a plant based algae Schizochytrium sp. Genus: Schizochytrium Species: sp.) (Alt. Name: DHA)100 mgper 1 Packet(s)DSLD:29566
- SuntoryDHA & EPA Sesamin EX300 mgper 4 Softgel(s)DSLD:174978
- SuperSmartSuper Omega 3 1500 mgFish Oil · in Triglyceride form345 mgper 1 Softgel(s)DSLD:315661
- Supplement SpotEssential Prostate Packfish oil100 mgper 1 Packet(s)DSLD:264557
- SwansonBrain Essentials30 mgper 1 Veggie Capsule(s)DSLD:308484
- SynergyNorwegian Cod Liver Oil Lemon500 mgper 5 mLDSLD:277453
- Systemic Formulas Bio NutrimentOMGA LQ236.6 mgper 2 mLDSLD:22120
- The Honest Co.Baby DHA95 mgper 1 mLDSLD:206813
- The Honest Co.DHA/Omega-3250 mgper 1 Softgel(s)DSLD:73709
- The Vitamin ShoppeAdvanced Ocular SupportFish Oil · Docosahexaenoic Acid (Form: from Fish Oil) (Alt. Name: DHA)50 mgper 2 Veggie Capsule(s)DSLD:35605
- The Vitamin ShoppeGinkgo Neuro-Mind 60 mg50 mgper 1 Tablet(s)DSLD:36283
- The Vitamin ShoppeOmega 3 Fish Oil 800 EPA/500 DHA500 mgper 1 Teaspoon(s)DSLD:26980
- The Vitamin ShoppePrenatal + DHA50 mgper 4 Tablet(s)DSLD:37603
- Theralogix Nutritional ScienceTheraNatal Complete Softgel300 mgper 1 Softgel(s)DSLD:283003
- Theralogix Nutritional ScienceTheraNatal One300 mgper 1 Softgel(s)DSLD:282955
- ThorneSynaQuellAlgal Oil125 mgper 7.8 Gram(s)DSLD:337875
- ThorneVeganPro Complex Chocolate FlavoredAlgal Oil200 mgper 52.3 Gram(s)DSLD:313925
- TN Trusted NutrientsDHADHA (Alt. Name: Docosahexaenoic Acid) Note: from100 mgper 1 Softgel(s)DSLD:70305
- Trigen LaboratoriesTaron-Prex Prenatal with DHAFish Oil · DHA (Alt. Name: Docosahexaenoic Acid) Note: from approximately 350 mg of Omegas derived from approximately 580 mg purified fish oil265 mgper 1 Softgel Capsule(s)DSLD:241456
- Trigen LaboratoriesTL-SelectFish Oil325 mgper 1 Softgel Capsule(s)DSLD:264481
- Trigen LaboratoriesZatean -Pn DHA300 mgper 1 Softgel Capsule(s)DSLD:264497
- Trigen LaboratoriesZatean -Pn Plus300 mgper 1 Softgel Capsule(s)DSLD:264498
- Trigen LaboratoriesZatean-Pn DHA300 mgper 1 Capsule(s)DSLD:12964
- TruehopeOmegapower360 mgper 3 Softgel Capsule(s)DSLD:32361
- TruHeightKids Brain Growth Orange FlavorAlgal Oil100 mgper 2 Gummy(ies)DSLD:322969
- Vertical PharmaceuticalsOB Complete Chewable100 mgper 1 Chewable Tablet(s)DSLD:264181
- VigorSourceAlaska Deep Sea Fish Oil King240 mgper 1 Softgel(s)DSLD:12936
- Village VitalityKrill Oil37.5 mgper 1 Softgel(s)DSLD:310246
- VinsicCompound Neuralgic AcidAlgal Oil80 mgper 2 Softgel(s)DSLD:335760
- Virtus PharmaceuticalsVirt-PN DHAFish Oil · Docosahexaenoic Acid (Alt. Name: DHA) Note: from at least 330 mg purified fish oils.300 mgper 1 Softgel(s)DSLD:180546
- Virtus PharmaceuticalsVirt-PN PlusFish Oil · Docosahexaenoic Acid (Alt. Name: DHA) Note: from at least 340 mg omega-3s from at least 390 purified fish oils.300 mgper 1 Softgel(s)DSLD:180537
- VitabaseBrain Support100 mgper 2 Capsule(s)DSLD:7004
- VitabaseComplete Essential Fatty Acids46 mgper 1 Softgel(s)DSLD:6864
- VitabaseKrill Oil 500 mg52 mgper 1 Softgel(s)DSLD:6160
- VitabaseMaxEPA Omega-3 1000 mg120 mgper 1 Softgel(s)DSLD:6906
- VitabaseNeuromins DHA 100 mgMicroalgae Oil · DHA (Form: from microalgae oil) (Alt. Name: docosahexaenoic acid) Note: Neuromins(TM) is a highly-purified source of DHA from microalgae. It is produced under strict quality control conditions and is free of chemical pollutants and toxins.100 mgper 1 Softgel(s)DSLD:7176
- VitaCeutical LabsCardio Support Softgels80 mgper 1 Softgel(s)DSLD:6276
- VitaCeutical LabsEPA & DHA120 mgper 1 Softgel(s)DSLD:53841
- VitaCeutical LabsEPA & DHA120 mgper 1 Softgel(s)DSLD:6307
- VitaCeutical LabsKrill Oil37.5 mgper 1 Softgel(s)DSLD:53560
- VitaCeutical LabsPrenatal With DHAAlgae · DHA (Form: from Algae)50 mgper 3 Tablet(s)DSLD:53993
- Vital NutrientsUltra Omega CombinationDHA (Alt. Name: Docosahexaenoic Acid) Note: 160-176mg176 mgper 2 Softgel(s)DSLD:6322
- Vital NutrientsUltra Pure Cod Liver Oil 1025 Lemon Flavored460 mgper 5 mLDSLD:305170
- Vital NutrientsUltra Pure Fish Oil 350 Lemon Flavor240 mgper 1 Softgel(s)DSLD:223052
- Vital NutrientsUltra Pure Fish Oil 350 Lemon Flavor240 mgper 2 Softgel(s)DSLD:305174
- Vital NutrientsUltra Pure Omega CombinationDHA (Alt. Name: Docosahexaenoic Acid) Note: 160-176mg176 mgper 2 Softgel(s)DSLD:27523
- vitaMedMDOne RxAlgal Oil200 mgper 1 Softgel(s)DSLD:264217
- Vitamer LaboratoriesHigh Potency Liquid Omega-3440 mgper 1 tspDSLD:53242
- Vitamer LaboratoriesHigh Potency Liquid Omega-3 Orange425 mgper 1 tspDSLD:53168
- Vitamer LaboratoriesKrill Oil37.5 mgper 1 Softgel(s)DSLD:23274
- Vitamer LaboratoriesKrill Oil37.5 mgper 1 Softgel(s)DSLD:67592
- Vitamer LaboratoriesPrenatal Multi Once Daily CapsAlgae · DHA (Form: from Algae)15 mgper 1 Capsule(s)DSLD:68796
- Vitamer LaboratoriesPrenatal With DHAAlgae · DHA (Form: from Algae) (Alt. Name: Docosahexaenoic Acid)50 mgper 1 Tablet(s)DSLD:69230
- Vitamin WorldDHA 100 mg100 mgper 1 Softgel(s)DSLD:66291
- Vitamin WorldNeuro-PS Gold Plus10 mgper 3 Softgel(s)DSLD:67655
- Vitamin WorldPre & Post Natal DHA 100 mgAlgae · Docosahexaenoic Acid (Alt. Name: DHA) Note: from DHA rich oil derived from a plant based algae100 mgper 1 Softgel(s)DSLD:21071
- Viva NaturalsLiquid Omega-3 Fish Oil Lemon SwirlDHA (Form: as TG) (Alt. Name: Docosahexaenoic Acid)510 mgper 5 mLDSLD:248115
- Viva NaturalsTriple-Strength Omega-3 Fish OilDHA (Form: as TG) (Alt. Name: Docosahexaenoic Acid)480 mgper 2 Softgel(s)DSLD:247978
- Viva NaturalsTriple-Strength Omega-3 Fish OilDHA (Form: as TG) (Alt. Name: Docosahexaenoic Acid)480 mgper 2 Softgel(s)DSLD:248141
- Viva VitaminsFish Oil Omega-3120 mgper 1 Softgel(s)DSLD:1792
- VQ Verified QualityOmega 3 Fish Oil 180 mg EPA/120 mg DHA Lemon FlavorDHA Note: 120-140mg140 mgper 1 Softgel(s)DSLD:33987
- Well at WalgreensSoftgelSchizochytrium sp. oil200 mgper 1 Softgel(s)DSLD:274227
- Well At WalgreensPrenatal Multi + DHAAlgal Oil · DHA (Form: from Algal Oil) (Alt. Name: Docosahexaenoic acid)250 mgper 1 Softgel(s)DSLD:207376
- Whole FoodsPrenatal EssentialsAlgae · DHA (Form: from Algae)25 mgper 3 Tablet(s)DSLD:26523
- Wholesome StoryMale Fertility SupportAlgae100 mgper 3 Capsule(s)DSLD:335612
- Wholly LiquidOmega Plus300 mgper 1 Softgel(s)DSLD:272113
- Wholly LiquidOmega Plus300 mgper 1 Softgel(s)DSLD:321788
- Women's Choice PharmaceuticalsDHA/EPA Capsule230 mgper 1 Capsule(s)DSLD:241428
- Women's Choice PharmaceuticalsNestabs OneAlgal Oil225 mgper 1 Softgel(s)DSLD:279130
- Womens Choice PharmaceuticalsOmega 3-DHA120 mgper 1 Softgel(s)DSLD:37269
- Wonder LaboratoriesDHA 100 mgFish Oil100 mgper 1 Softgel(s)DSLD:260684
- Wonder LaboratoriesDHA 100 mgFish Oil100 mgper 1 Softgel(s)DSLD:260924
- Wonder LaboratoriesDHA 100 mgFish Oil100 mgper 1 Softgel(s)DSLD:315170
- Wonder LaboratoriesDHA 100 mgFish Oil100 mgper 1 Softgel(s)DSLD:315671
- WP Westminster PharmaceuticalsWesCap-PN DHA300 mgper 1 Softgel(s)DSLD:278685
- WP Westminster PharmaceuticalsWestGel DHA200 mgper 1DSLD:264460
- XYMOGENBrainSustain Creamy ChocolateAlgal Oil · life'sDHA DHA (Form: from Algal oil) (Alt. Name: Docosahexaenoic Acid)50 mgper 51 Gram(s)DSLD:240120
- XYMOGENBrainSustain Vanilla DelightAlgal Oil · life'sDHA DHA (Form: from Algal oil) (Alt. Name: Docosahexaenoic Acid)50 mgper 48 Gram(s)DSLD:218511
- XYMOGENDHA from AlgaeAlgal Oil · life'sDHA DHA (Form: from Algal oil) (Alt. Name: Docosahexaenoic Acid)200 mgper 1 Vegetarian Softgel(s)DSLD:218646
- XYMOGENDr. Perlmutter's DHA From Algae For KidsAlgal Oil · DHA (Form: from Algal Oil) (Alt. Name: Docosahexaenoic Acid)100 mgper 1 Vegetarian Softgel(s)DSLD:27847
- XYMOGENMaX Liv DetoxAlgal Oil · DHA (Form: from Algal Oil) (Alt. Name: Docosahexaenoic Acid)5 mgper 2 Capsule(s)DSLD:49608
- ZahlerOmega 3 Liquid820 mgper 1 tspDSLD:33312
- ZahlerOmega 3 Liquid820 mgper 1 tspDSLD:33314
Label record: NIH Office of Dietary Supplements · CC0
Where it reaches
10 systems, 28 regions, 166 tissues, 255 transporter routes — routes, not measurements: transporters known to carry all-cis-docosa-4,7,10,13,16,19-hexaenoic acid are expressed there, and no source reports it arriving.
Loading the model…
Papers screened
1,487 papers
- Compound
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid
- Screened
- 1,487
- Admitted
- 5
- Discarded
- 1,105
- Not read
- 377
- Showing
- 200 of 1,487
Read and discarded1,105 papers
- PMID:12391014cited by PMID:19804838; not about the subject it would be filed under2026-10-12
- PMID:12590139cited by PMID:19804838; not about the subject it would be filed under2026-10-12
- PMID:12923200cited by PMID:19804838; not about the subject it would be filed under2026-10-12
- PMID:13130128cited by PMID:19804838; not about the subject it would be filed under2026-10-12
- PMID:14715958cited by PMID:19804838; not about the subject it would be filed under2026-10-12
- PMID:15569878cited by PMID:19804838; not about the subject it would be filed under2026-10-12
- PMID:15590152cited by PMID:19804838; not about the subject it would be filed under2026-10-12
- PMID:15718470cited by PMID:19804838; not about the subject it would be filed under2026-10-12
- PMID:15852374cited by PMID:19804838; not about the subject it would be filed under2026-10-12
- PMID:16040805cited by PMID:19804838; not about the subject it would be filed under2026-10-12
- PMID:16151530cited by PMID:19804838; not about the subject it would be filed under2026-10-12
- PMID:16432513cited by PMID:19804838; not about the subject it would be filed under2026-10-12
and 1,093 more.
Not read yet377 papers
and 377 more.
Measured, not recorded
- Compound
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid
- Endpoints measured
- 633 endpoints
- Recorded as a finding
- No
Show what was measured
HDL-cholesterol (HDL-C)
increases, 0.07 mmol/L (95% CI: 0.05-0.10)
The pooled estimate for the change in TG concentration was -0.20 mmol/L (95% CI: -0.27 to -0.14), 0.23 mmol/L (95% CI: 0.16-0.30) for LDL-C, and 0.07 mmol/L (95% CI: 0.05-0.10) for HDL-C.
PMID:22113870 · one of two readings recorded this
LDL-cholesterol (LDL-C)
increases, 0.23 mmol/L (95% CI: 0.16-0.30)
The pooled estimate for the change in TG concentration was -0.20 mmol/L (95% CI: -0.27 to -0.14), 0.23 mmol/L (95% CI: 0.16-0.30) for LDL-C, and 0.07 mmol/L (95% CI: 0.05-0.10) for HDL-C.
PMID:22113870 · one of two readings recorded this
serum triglycerides (TG)
decreases, -0.20 mmol/L (95% CI: -0.27 to -0.14)
The pooled estimate for the change in TG concentration was -0.20 mmol/L (95% CI: -0.27 to -0.14), 0.23 mmol/L (95% CI: 0.16-0.30) for LDL-C, and 0.07 mmol/L (95% CI: 0.05-0.10) for HDL-C.
PMID:22113870 · one of two readings recorded this
brain DHA uptake / brain DHA levels
decreases, markedly reduced levels of DHA in brain of Mfsd2a-knockout mice
Lipidomic analysis indicates that Mfsd2a-deficient (Mfsd2a-knockout) mice show markedly reduced levels of DHA in brain accompanied by neuronal cell loss in hippocampus and cerebellum, as well as cognitive deficits and severe anxiety, and microcephaly.
PMID:24828044 · one of two readings recorded this
DHA levels in brain, lipidomic analysis
decreases
Lipidomic analysis indicates that Mfsd2a-deficient (Mfsd2a-knockout) mice show markedly reduced levels of DHA in brain accompanied by neuronal cell loss in hippocampus and cerebellum, as well as cognitive deficits and severe anxiety, and microcephaly.
PMID:24828044 · one of two readings recorded this
episodic memory, adults with mild memory complaints (MMC)
increases, Hedge's g z = 2.86 (p = 0.004), p = 0.004, n = 18
In the a priori meta-analysis model of adults with MMC, episodic memory significantly (P<.004) improved in response to DHA supplementation, alone or in combination with EPA; Table 2).
PMID:25786262 · one of two readings recorded this
episodic memory, pooled between-group (all subjects)
no effect, WGMD 0.08 (z=1.777, p=0.076); Hedge's g z=1.647 (p=0.10), p = 0.076, n = 62
The overall model and the analysis of episodic memory in response to DHA/EPA supplementation among adults with no cognitive complaints at baseline was not significant (Table 2).
PMID:25786262 · one of two readings recorded this
episodic, semantic and working memory, pooled weighted mean difference and Hedge's g across neuropsychological memory tests
no effect, overall between-group episodic memory model not significant (WGMD 0.08, z=1.777, p=0.076; Hedge's g z=1.647, p=0.10), p = 0.076, n = 62
Not recorded as a finding: the intervention held more than the compound
The overall model and the analysis of episodic memory in response to DHA/EPA supplementation among adults with no cognitive complaints at baseline was not significant (Table 2).
PMID:25786262 · one of two readings recorded this
semantic memory, pooled between-group
no effect, n = 15
No significant effects of DHA/EPA supplementation were found for any of the between group models analyzed (See Supporting Information— S3 Table).
PMID:25786262 · one of two readings recorded this
working memory, pooled between-group
no effect, n = 21
No significant effects of DHA/EPA supplementation were found for any of the between group models analyzed (See Supporting Information— S4 Table).
PMID:25786262 · one of two readings recorded this
Baseline diastolic blood pressure, 1 g/day group
no effect, p = 0.58
with a trend towards lower systolic (p = 0.07) but not diastolic (p = 0.58) blood pressure in the 1 g/day group
PMID:30297663 · one of two readings recorded this
Baseline fasting plasma triglyceride, whole cohort
no effect, p = 0.56
The average baseline fasting TG level of the study cohort was 1.23 ± 0.47 mmol/L (mean ± standard deviation (SD)), with no difference between dose groups (p = 0.56)
PMID:30297663 · one of two readings recorded this
Baseline plasma total cholesterol between groups
no effect, p = 0.98
There was no difference between groups in baseline plasma TC levels (p = 0.98)
PMID:30297663 · one of two readings recorded this
Baseline systolic blood pressure, 1 g/day group
no effect, p = 0.07
with a trend towards lower systolic (p = 0.07) but not diastolic (p = 0.58) blood pressure in the 1 g/day group
PMID:30297663 · one of two readings recorded this
BMI as predictor of baseline plasma triglyceride
increases, p = 0.03
BMI was a weak but significant predictor of baseline plasma TG levels (R2 = 0.09, p = 0.03)
PMID:30297663 · one of two readings recorded this
Change in proportion of HDL2a particles, predicted by change in LDL peak particle size
unclear, p = 0.003
HDL2a (R2 = 0.28, p = 0.003)
PMID:30297663 · one of two readings recorded this
Change in proportion of HDL2b particles, predicted by change in LDL peak particle size
unclear, p = 0.0008
the change in LDL peak particle size was a predictor of the change in the proportion of HDL2b (R2 = 0.34, p = 0.0008)
PMID:30297663 · one of two readings recorded this
Change in proportion of HDL2b particles, predicted by change in plasma TG
unclear, p = 0.04
The change in plasma TG levels was a predictor of the change in the proportion of HDL2b particles (R2 = 0.15, p = 0.04)
PMID:30297663 · one of two readings recorded this
Change in proportion of HDL3b particles, predicted by change in LDL peak particle size
unclear, p = 0.01
HDL3b (R2 = 0.20, p = 0.01)
PMID:30297663 · one of two readings recorded this
Diastolic blood pressure after supplementation, by n-3 LCPUFA dose
no effect, p = 0.91
After fish oil supplementation, both systolic (p = 0.16) and diastolic (p = 0.91) blood pressures were unaffected by n-3 LCPUFA dose
PMID:30297663 · one of two readings recorded this
fasting plasma triglycerides (autoanalyser enzymatic kit, fast over 10 h), pre-menopausal women, 8 weeks of HiDHA tuna oil at 0, 0.35, 0.7 or 1 g/day n-3 LCPUFA
decreases
Not recorded as a finding: the intervention held more than the compound
Following 8 weeks of supplementation with 1 g/day n-3 LCPUFA, plasma TG levels significantly lowered compared to placebo (Table 2).
PMID:30297663 · one of two readings recorded this
fasting plasma triglycerides (enzymatic autoanalyser, overnight fast over 10 h) after 8 weeks at 1 g/day n-3 LCPUFA as HiDHA tuna oil versus Sunola oil placebo; also total cholesterol, lipoprotein particle size, Omega-3 Index
decreases, n = 53
Not recorded as a finding: the intervention held more than the compound
Following 8 weeks of supplementation with 1 g/day n-3 LCPUFA, plasma TG levels significantly lowered compared to placebo (Table 2).
PMID:30297663 · one of two readings recorded this
HDL3-C, placebo vs 0.35 and 0.7 g/day groups
unclear
The significant difference between HDL3-C levels in the placebo group and the 0.35 and 0.7 g/day groups was driven by an unexplained increase in the placebo group rather than a reduction in the treatment groups
PMID:30297663 · one of two readings recorded this
IDL, LDL and HDL particle composition
no effect
IDL, LDL, and HDL particle compositions were unaffected by n-3 LCPUFA supplementation (Table 4)
PMID:30297663 · one of two readings recorded this
LDL particle size
no effect
small dense LDL3 particles present in very few subjects and no particle size change upon n-3 LCPUFA supplementation (Table 5)
PMID:30297663 · one of two readings recorded this
Omega-3 Index (erythrocyte EPA + DHA), increase
increases
resulting in a 15% increase in the Omega-3 Index (erythrocyte EPA + DHA as mol % of total fatty acids) after 0.35 g/day, and increases of 27% and 39% after 0.7 g/day and 1 g/day n-3 LCPUFA, respectively
PMID:30297663 · one of two readings recorded this
Omega-3 Index (erythrocyte EPA + DHA), increase
increases
resulting in a 15% increase in the Omega-3 Index (erythrocyte EPA + DHA as mol % of total fatty acids) after 0.35 g/day, and increases of 27% and 39% after 0.7 g/day and 1 g/day n-3 LCPUFA, respectively
PMID:30297663 · one of two readings recorded this
Omega-3 Index (erythrocyte EPA + DHA), increase
increases
resulting in a 15% increase in the Omega-3 Index (erythrocyte EPA + DHA as mol % of total fatty acids) after 0.35 g/day, and increases of 27% and 39% after 0.7 g/day and 1 g/day n-3 LCPUFA, respectively
PMID:30297663 · one of two readings recorded this
Plasma total cholesterol dose-response after supplementation
no effect, p = 0.64
no dose–response effect following n-3 LCPUFA supplementation (p = 0.64)
PMID:30297663 · one of two readings recorded this
Plasma triglyceride, change from baseline
decreases
This change amounted to a 23% reduction from baseline
PMID:30297663 · one of two readings recorded this
Plasma triglyceride dose-response, intention-to-treat
decreases, p = 0.04
In an intention-to-treat analysis, plasma TG levels lowered according to increasing dose (R2 = 0.09, p = 0.04)
PMID:30297663 · one of two readings recorded this
Plasma triglyceride dose-response, per-protocol
decreases, p = 0.003
The dose effect increased upon a per-protocol analysis (R2 = 0.16, p = 0.003)
PMID:30297663 · one of two readings recorded this
Post-intervention VLDL-TG, 1 g/day vs 0.35 g/day
decreases
Post-intervention VLDL-TG levels in the group supplemented with 1 g/day n-3 LCPUFA were significantly lower (32%) than the 0.35 g/day group
PMID:30297663 · one of two readings recorded this
Post-intervention VLDL-TG, 1 g/day vs placebo
no effect
they were not significantly lower than placebo due to the apparent VLDL-TG reduction in this group (Table 3)
PMID:30297663 · one of two readings recorded this
Proportion of HDL2b particles
increases
There was a very weak dose-dependent increase in the proportion of HDL2b particles but not in HDL2a or HDL3a (Table 5)
PMID:30297663 · one of two readings recorded this
Systolic blood pressure after supplementation, by n-3 LCPUFA dose
no effect, p = 0.16
After fish oil supplementation, both systolic (p = 0.16) and diastolic (p = 0.91) blood pressures were unaffected by n-3 LCPUFA dose
PMID:30297663 · one of two readings recorded this
Child age at measurement as predictor of diastolic blood pressure
unclear, p = 0.001
DBP: F = 7.39; P = .001
PMID:30794304 · one of two readings recorded this
Child age at measurement as predictor of systolic blood pressure
unclear, p = 0.001
child age, SBP: F = 7.385; P = .001
PMID:30794304 · one of two readings recorded this
childhood systolic and diastolic blood pressure at 4-6 years, mixed models; mothers given 600 mg/day DHA vs placebo in pregnancy, outcome in children; finding reported only in children who were overweight or obese (treatment by weight-status interaction)
decreases, SBP 104.28 vs 100.34 mm Hg; DBP 64.7 vs 59.76 mm Hg (placebo vs DHA, overweight or obese children)
Not recorded as a finding: every result is a subgroup, with no whole-population estimate
Children who were overweight or obese whose mothers received placebo during pregnancy had higher SBP and DBP compared with children who were overweight or obese whose mothers received DHA (mean [SE] SBP, 104.28 [1.37] mm Hg vs 100.34 [1.02] mm Hg; DBP, 64.7 [1.23] mm Hg vs 59.76 [0.91] mm Hg).
PMID:30794304 · one of two readings recorded this
childhood systolic and diastolic blood pressure at 4 to 6 years in offspring of mothers given 600 mg/d DHA in pregnancy; reported only by child weight-status stratum (overweight or obese versus not); abstract only
decreases, SBP 100.34 vs 104.28 mm Hg; DBP 59.76 vs 64.7 mm Hg in overweight or obese children, DHA versus placebo, n = 171
Not recorded as a finding: every result is a subgroup, with no whole-population estimate
Children who were overweight or obese whose mothers received placebo during pregnancy had higher SBP and DBP compared with children who were overweight or obese whose mothers received DHA (mean [SE] SBP, 104.28 [1.37] mm Hg vs 100.34 [1.02] mm Hg; DBP, 64.7 [1.23] mm Hg vs 59.76 [0.91] mm Hg).
PMID:30794304 · one of two readings recorded this
Diastolic blood pressure in children aged 4 to 6 years
decreases
DBP, 64.7 [1.23] mm Hg vs 59.76 [0.91] mm Hg
PMID:30794304 · one of two readings recorded this
Maternal prepregnancy BMI as predictor of child diastolic blood pressure
increases, p = 0.01
DBP: r = 0.216; P = .01
PMID:30794304 · one of two readings recorded this
Maternal prepregnancy BMI as predictor of child systolic blood pressure
increases, p = 0.001
prepregnancy BMI, SBP: r = 0.284; P = .001
PMID:30794304 · one of two readings recorded this
Systolic and diastolic blood pressure, children not overweight or obese vs overweight or obese children of DHA mothers
no effect
No differences in the SBP and DBP were found between children who were overweight or obese whose mothers received DHA and children who were not overweight or obese
PMID:30794304 · one of two readings recorded this
Systolic blood pressure in children aged 4 to 6 years
decreases
mean [SE] SBP, 104.28 [1.37] mm Hg vs 100.34 [1.02] mm Hg
PMID:30794304 · one of two readings recorded this
Inflammatory markers in maternal and infant plasma, correlation with RBC DHA
decreases
Decreases in inflammation were observed in both maternal and infant plasma and correlated with red blood cell (RBC) DHA levels
PMID:31058771 · one of two readings recorded this
inflammatory markers in maternal and infant plasma; mothers of extremely preterm infants assigned 200 or 1000 mg/day DHA, so both arms were exposed; abstract only
decreases
Not recorded as a finding: the comparison was against another active treatment
Decreases in inflammation were observed in both maternal and infant plasma and correlated with red blood cell (RBC) DHA levels.
PMID:31058771 · one of two readings recorded this
Caregiver-reported child sleep, change over 180 days, entire cohort
no effect
Differences in change between the DHA+AA and placebo groups after 180 days of supplementation were not statistically significant for the entire cohort
PMID:31538590 · one of two readings recorded this
caregiver-reported toddler sleep (nocturnal and total sleep, sleep problems), Brief Infant Sleep Questionnaire, 180 days of supplementation in children born preterm
no effect, difference in change between DHA+AA and placebo not statistically significant for the entire cohort
Not recorded as a finding: the intervention held more than the compound
Differences in change between the DHA+AA and placebo groups after 180 days of supplementation were not statistically significant for the entire cohort.
PMID:31538590 · one of two readings recorded this
caregiver-reported toddler sleep (nocturnal sleep, total sleep, sleep problems) on the Brief Infant Sleep Questionnaire, change over 180 days; abstract only
no effect
Not recorded as a finding: the intervention held more than the compound
Differences in change between the DHA+AA and placebo groups after 180 days of supplementation were not statistically significant for the entire cohort.
PMID:31538590 · one of two readings recorded this
Nocturnal sleep change
increases, p = 0.006
difference in nocturnal sleep change = 1.07, effect size = 0.65, P = .006
PMID:31538590 · one of two readings recorded this
Nocturnal sleep change
increases, p = 0.04
difference in nocturnal sleep change = 0.44, effect size = 0.26, P = .04
PMID:31538590 · one of two readings recorded this
Sleep problems
decreases
sleep problems odds ratio = 0.36, 95% confidence interval = 0.15, 0.82
PMID:31538590 · one of two readings recorded this
Total sleep change
increases, p = 0.04
difference in total sleep change = 1.10, effect size = 0.50, P = .04
PMID:31538590 · one of two readings recorded this
13C-DHA accumulation in red cell phosphatidylcholine
no effect
No significant differences were found for these kinetics for both sources.
PMID:31963708 · one of two readings recorded this
13C-DHA accumulation in red cell phosphatidylethanolamine
increases
When studying the accumulation of 13C-DHA into PE, it tended to plateauing at 144 h from 13C-DHA-TAG whereas it sharply increased at this latter time from 13C-AceDoPC, with around twice as much of 13C-DHA from AceDoPC.
PMID:31963708 · one of two readings recorded this
13C-DHA enrichment in plasma phospholipids after the peak
increases
After peaking, the 13C enrichment in DHA decreased at 72 h from both sources but remained significantly different.
PMID:31963708 · one of two readings recorded this
13C-DHA enrichment in plasma phospholipids and red-cell PC and PE after a single 50 mg 13C-DHA dose as 13C-AceDoPC versus 13C-DHA triacylglycerol, GC-C-IRMS; three men, crossover
peak 5386 pmol/mL from AceDoPC versus 3247 pmol/mL from TAG-DHA, n = 3
Not recorded as a finding: the comparison was against another active treatment
However, the 13 C-DHA peak was 2-fold higher from AceDoPC (5386 pmol/mL) compared to TAG-DHA (3247 pmol/mL).
PMID:31963708 · one of two readings recorded this
13C-DHA enrichment in plasma phospholipids and red cell phosphatidylcholine/ethanolamine, GC-C-IRMS, after 50 mg 13C-DHA as AceDoPC versus as triacylglycerol, crossover in three men
peak 5386 vs 3247 pmol/mL (AceDoPC vs TAG-DHA), n = 3
Not recorded as a finding: the comparison was against another active treatment
However, the 13 C-DHA peak was 2-fold higher from AceDoPC (5386 pmol/mL) compared to TAG-DHA (3247 pmol/mL).
PMID:31963708 · one of two readings recorded this
Peak 13C-DHA in plasma phospholipids
increases
However, the 13 C-DHA peak was 2-fold higher from AceDoPC (5386 pmol/mL) compared to TAG-DHA (3247 pmol/mL)
PMID:31963708 · one of two readings recorded this
bronchopulmonary dysplasia (BPD) at 36 weeks postmenstrual age
The meta-analysis of these studies showed that DHA supplementation did not decrease the risk of BPD at 36 weeks of postmenstrual age among preterm infants (low certainty of evidence).
PMID:32456494 · one of two readings recorded this
Bronchopulmonary dysplasia among surviving infants, absolute difference
increases, p = 0.01
Bronchopulmonary dysplasia occurred in 41.7% of surviving infants in the DHA group vs 31.4% in the placebo group (absolute difference, 11.5% [95% CI, 2.3% to 23.2%]; relative risk, 1.36 [95% CI, 1.07 to 1.73], P = .01)
PMID:32662862 · one of two readings recorded this
Bronchopulmonary dysplasia among surviving infants
increases, p = 0.01
Bronchopulmonary dysplasia occurred in 41.7% of surviving infants in the DHA group vs 31.4% in the placebo group (absolute difference, 11.5% [95% CI, 2.3% to 23.2%]; relative risk, 1.36 [95% CI, 1.07 to 1.73], P = .01)
PMID:32662862 · one of two readings recorded this
Bronchopulmonary dysplasia-free survival at 36 weeks' postmenstrual age, absolute difference
no effect, p = 0.18
147 of 268 infants (54.9%) in the DHA group vs 157 of 255 infants (61.6%) in the placebo group survived without bronchopulmonary dysplasia (absolute difference, -5.0% [95% CI, -11.6% to 2.6%]; relative risk, 0.91 [95% CI, 0.80 to 1.04], P = .18)
PMID:32662862 · one of two readings recorded this
Bronchopulmonary dysplasia-free survival at 36 weeks' postmenstrual age
no effect, p = 0.18
147 of 268 infants (54.9%) in the DHA group vs 157 of 255 infants (61.6%) in the placebo group survived without bronchopulmonary dysplasia (absolute difference, -5.0% [95% CI, -11.6% to 2.6%]; relative risk, 0.91 [95% CI, 0.80 to 1.04], P = .18)
PMID:32662862 · one of two readings recorded this
bronchopulmonary dysplasia-free survival in infants at 36 weeks' postmenstrual age (primary outcome); mothers dosed 1.2 g/d DHA, outcome measured in their breastfed preterm infants; also mortality and bronchopulmonary dysplasia in survivors, abstract only
RR 0.91 (95% CI 0.80 to 1.04), p = 0.18, n = 523
Not recorded as a finding: this platform holds no node for the endpoint
Overall, 147 of 268 infants (54.9%) in the DHA group vs 157 of 255 infants (61.6%) in the placebo group survived without bronchopulmonary dysplasia (absolute difference, -5.0% [95% CI, -11.6% to 2.6%]; relative risk, 0.91 [95% CI, 0.80 to 1.04], P = .18).
PMID:32662862 · one of two readings recorded this
bronchopulmonary dysplasia in surviving infants at 36 weeks' postmenstrual age (and BPD-free survival, mortality), after maternal oral DHA 1.2 g/d vs placebo capsules; mothers dosed, outcome in preterm infants
BPD 41.7% vs 31.4% of survivors, RR 1.36 (95% CI 1.07 to 1.73), p = 0.01
Not recorded as a finding: the paper never states the instrument the node requires
Bronchopulmonary dysplasia occurred in 41.7% of surviving infants in the DHA group vs 31.4% in the placebo group (absolute difference, 11.5% [95% CI, 2.3% to 23.2%]; relative risk, 1.36 [95% CI, 1.07 to 1.73], P = .01).
PMID:32662862 · one of two readings recorded this
Mortality, absolute difference
no effect, p = 0.12
Mortality occurred in 6.0% of infants in the DHA group vs 10.2% of infants in the placebo group (absolute difference, -3.9% [95% CI, -6.8% to 1.4%]; relative risk, 0.61 [95% CI, 0.33 to 1.13], P = .12)
PMID:32662862 · one of two readings recorded this
Mortality
no effect, p = 0.12
Mortality occurred in 6.0% of infants in the DHA group vs 10.2% of infants in the placebo group (absolute difference, -3.9% [95% CI, -6.8% to 1.4%]; relative risk, 0.61 [95% CI, 0.33 to 1.13], P = .12)
PMID:32662862 · one of two readings recorded this
Prespecified secondary outcomes (22)
no effect
Of 22 prespecified secondary outcomes, 19 were not significantly different
PMID:32662862 · one of two readings recorded this
Adherence by pill count
no effect
Mean adherence by pill count in the overall sample was 80.4% (placebo mean (SD)=79.8 (21.8); DHA mean (SD)=80.9 (17.3))
PMID:32690472 · one of two readings recorded this
Association of change in plasma DHA with change in CSF DHA
increases, p = 0.001
Increasing plasma DHA was associated with an increase in CSF DHA (R = 0.91, p<0.001; Supp Figure 1a)
PMID:32690472 · one of two readings recorded this
Baseline age
no effect, p = 0.46
Age in years, median (min, max) | 69 (58, 79) | 68.5 (58, 90) | 0.46
PMID:32690472 · one of two readings recorded this
Baseline BMI
no effect, p = 0.13
BMI (kg/m2), median (IQR) | 32.0 (7.3) | 27.8 (5.8) | 0.13
PMID:32690472 · one of two readings recorded this
Baseline correlation of CSF DHA with CSF Aβ42
increases, p = 0.0033
higher CSF DHA levels were significantly correlated with higher CSF Aβ42 (r = 0.54; p = 0.0033)
PMID:32690472 · one of two readings recorded this
Baseline HgbA1c
no effect, p = 0.66
HgbA1c (%), median (IQR) | 5.7 (0.2) | 5.8 (0.6) | 0.66
PMID:32690472 · one of two readings recorded this
Baseline male participants
no effect, p = 0.37
Males, n (%) | 4 (27%) | 2 (11%) | 0.37
PMID:32690472 · one of two readings recorded this
Baseline MoCA
no effect, p = 0.62
MoCA, median (min, max) b | 27 (22, 30) | 28 (19, 30) | 0.62
PMID:32690472 · one of two readings recorded this
change in cerebrospinal fluid DHA concentration (primary), CSF fatty acids by GC-MS, 6 months of DHA 2152 mg/day vs corn/soy oil placebo, vitamin B complex in both arms
increases, mean difference 0.08 (95% CI 0.05, 0.10) ug/ml, n = 26
Not recorded as a finding: this platform holds no node for the endpoint
After six months of DHA supplementation, there was a significant increase in CSF DHA in the DHA supplement arm (n = 13) compared with placebo (n = 13) (mean difference (95% CI): 0.08 (0.05, 0.10) µg/ml; p<0.0001; Fig. 2a).
PMID:32690472 · one of two readings recorded this
Change in Craft Stories delayed recall
no effect, p = 0.52
Craft delayed recall | 0.4 (2.8) | 1.1 (2.8) | 0.7 (−1.5, 2.8) | 0.52
PMID:32690472 · one of two readings recorded this
Change in Craft Stories immediate recall
no effect, p = 0.23
Craft immediate recall | 1.7 (3.1) | 0.3 (3.2) | −1.4 (−3.9, 1.0) | 0.23
PMID:32690472 · one of two readings recorded this
Change in CSF arachidonic acid
no effect, p = 0.35
Levels of CSF AA did not differ after DHA treatment (−0.02 (−0.07, 0.02) µg/ml, p = 0.35)
PMID:32690472 · one of two readings recorded this
Change in CSF DHA/AA ratio
increases, p = 0.0001
CSF DHA/AA was increased among those taking DHA supplements compared with those taking placebo (0.27 (0.20, 0.34), p<0.0001)
PMID:32690472 · one of two readings recorded this
Change in CSF DHA
increases, p = 0.0001
there was a significant increase in CSF DHA in the DHA supplement arm (n = 13) compared with placebo (n = 13) (mean difference (95% CI): 0.08 (0.05, 0.10) µg/ml; p<0.0001; Fig. 2a)
PMID:32690472 · one of two readings recorded this
Change in CSF DHA
unclear, p = 0.08
There was a trend for a greater increase in CSF DHA in APOE4 non-carriers compared to carriers (0.02 (−0.003, 0.04), p = 0.08, Cohen's effect size d = 0.41)
PMID:32690472 · one of two readings recorded this
Change in CSF EPA/AA ratio
increases, p = 0.0001
There was an increase in CSF EPA/AA among those taking DHA supplements versus placebo (0.03 (0.02, 0.04), p<0.0001)
PMID:32690472 · one of two readings recorded this
Change in CSF EPA/AA ratio
increases, p = 0.02
and was greater among non-carriers compared to APOE4 carriers (0.01 (0.002, 0.03), p = 0.02)
PMID:32690472 · one of two readings recorded this
Change in CSF EPA
increases, p = 0.0001
CSF EPA levels were increased after DHA supplementation (0.008 (0.004, 0.01) µg/ml; p <0.0001; Fig. 2b)
PMID:32690472 · one of two readings recorded this
Change in CSF EPA
increases, p = 0.001
Change in CSF EPA levels in both groups was significantly greater in APOE4 non-carriers compared to carriers (0.006 (0.003, 0.009) µg/ml; p = 0.001)
PMID:32690472 · one of two readings recorded this
Change in CVLT delayed recall
no effect, p = 0.53
CVLT delayed recall | 1.3 (2.6) | 1.9 (2.6) | 0.6 (−1.4, 2.6) | 0.53
PMID:32690472 · one of two readings recorded this
Change in CVLT Trial 5 (ranked)
no effect, p = 0.09
CVLT Trial 5 (ranked) | 9.9 (7.1) | 14.6 (7.2) | 4.7 (−0.8, 10.2) | 0.09
PMID:32690472 · one of two readings recorded this
Change in CVLT Trial 5
increases, p = 0.03
CVLT Trial 5 | −0.8 (2.1) | 1.1 (2.2) | 1.9 (0.2, 3.5) | 0.03
PMID:32690472 · one of two readings recorded this
Change in entorhinal cortex measure, Cohen's d
no effect
Cohen's effect size d of the hippocampal and entorhinal volume changes after treatment were 0.24 and 0.54 respectively
PMID:32690472 · one of two readings recorded this
Change in entorhinal cortex thickness
no effect, p = 0.13
no significant differences in the change of hippocampal volume (−0.002 (−0.009, 0.005), p = 0.56) or entorhinal cortex thickness (−0.11 (−0.25, 0.03), p = 0.13) between DHA and placebo treatment arms
PMID:32690472 · one of two readings recorded this
Change in hippocampal volume, Cohen's d
no effect
Cohen's effect size d of the hippocampal and entorhinal volume changes after treatment were 0.24 and 0.54 respectively
PMID:32690472 · one of two readings recorded this
Change in hippocampal volume
no effect, p = 0.56
no significant differences in the change of hippocampal volume (−0.002 (−0.009, 0.005), p = 0.56) or entorhinal cortex thickness (−0.11 (−0.25, 0.03), p = 0.13) between DHA and placebo treatment arms
PMID:32690472 · one of two readings recorded this
Change in MoCA
no effect, p = 0.4
MoCA | 0.3 (1.6) | −0.2 (1.6) | −0.5 (−1.7, 0.7) | 0.40
PMID:32690472 · one of two readings recorded this
Change in plasma arachidonic acid
decreases, p = 0.005
Plasma AA levels were significantly lower after DHA supplementation (−45.5 (−75.4, −15.6) µg/ml, p = 0.005)
PMID:32690472 · one of two readings recorded this
Change in plasma arachidonic acid
decreases, p = 0.05
This difference in change was significant among APOE4 non-carriers (−57.7 (−115.1, −0.4) µg/ml, p<0.05)
PMID:32690472 · one of two readings recorded this
Change in plasma DHA/AA ratio
increases, p = 0.0001
change in plasma DHA/AA ratio (0.63 (0.48, 0.78), p<0.0001), and plasma EPA/AA ratio (0.09 (0.03, 0.15), p = 0.004) differed by treatment group
PMID:32690472 · one of two readings recorded this
Change in plasma DHA
increases, p = 0.0001
Plasma DHA levels after DHA supplementation was increased compared with placebo (106.4 (87.8, 125.1) µg/ml, p<0.0001; Fig. 2c)
PMID:32690472 · one of two readings recorded this
Change in plasma DHA
no effect, p = 0.12
DHA and EPA plasma levels did not significantly differ between APOE4 carriers and non-carriers (DHA: 14.7 (−4.2, 33.7) µg/ml, p = 0.12; EPA: 4.4 (−3.4, 12.3) µg/ml, p = 0.25; Fig. 2B and D)
PMID:32690472 · one of two readings recorded this
Change in plasma EPA/AA ratio
increases, p = 0.004
change in plasma DHA/AA ratio (0.63 (0.48, 0.78), p<0.0001), and plasma EPA/AA ratio (0.09 (0.03, 0.15), p = 0.004) differed by treatment group
PMID:32690472 · one of two readings recorded this
Change in plasma EPA
increases, p = 0.002
EPA plasma levels were also increased with DHA supplementation (13.8 (5.8, 21.7) µg/ml, p = 0.002; Fig. 2d)
PMID:32690472 · one of two readings recorded this
Change in plasma EPA
no effect, p = 0.25
DHA and EPA plasma levels did not significantly differ between APOE4 carriers and non-carriers (DHA: 14.7 (−4.2, 33.7) µg/ml, p = 0.12; EPA: 4.4 (−3.4, 12.3) µg/ml, p = 0.25; Fig. 2B and D)
PMID:32690472 · one of two readings recorded this
Change in Trail Making Test A
no effect, p = 0.8
Trails A | −2.8 (10.2) | −3.8 (10.3) | −1.0 (−8.8, 6.9) | 0.80
PMID:32690472 · one of two readings recorded this
Change in Trail Making Test B
no effect, p = 0.74
Trails B b | −1.5 (40.0) | 3.5 (40.2) | 5.0 (−26.3, 36.3) | 0.74
PMID:32690472 · one of two readings recorded this
CSF DHA concentration change over 6 months, fatty acid methyl esters by GC-MS (primary outcome); CSF and plasma EPA also measured
increases, mean difference 0.08 (95% CI 0.05, 0.10) µg/ml, n = 26
Not recorded as a finding: this platform holds no node for the endpoint
After six months of DHA supplementation, there was a significant increase in CSF DHA in the DHA supplement arm (n = 13) compared with placebo (n = 13) (mean difference (95% CI): 0.08 (0.05, 0.10) µg/ml; p<0.0001; Fig. 2a).
PMID:32690472 · one of two readings recorded this
Percentage increase in CSF DHA
increases
participants in the DHA treatment arm exhibited a 200% increase in plasma DHA, but only a 28% increase in CSF DHA
PMID:32690472 · one of two readings recorded this
Percentage increase in plasma DHA
increases
participants in the DHA treatment arm exhibited a 200% increase in plasma DHA, but only a 28% increase in CSF DHA
PMID:32690472 · one of two readings recorded this
Treatment by APOE genotype interaction on change in CSF EPA
no effect, p = 0.54
Interaction of APOE genotype and treatment on the change in CSF EPA level was not significant (p = 0.54)
PMID:32690472 · one of two readings recorded this
Treatment by APOE genotype interaction on CSF arachidonic acid
no effect, p = 0.32
there was no interaction between treatment and APOE genotype on levels of CSF AA (p = 0.32)
PMID:32690472 · one of two readings recorded this
Treatment by APOE genotype interaction on plasma arachidonic acid
no effect, p = 0.4
The interaction between APOE genotype and treatment arm on plasma AA was not significant (p = 0.40)
PMID:32690472 · one of two readings recorded this
Treatment by APOE group interaction on change in CSF DHA
no effect, p = 0.61
the interaction between the treatment group and APOE group on the change of CSF DHA was not significant (p = 0.61; Fig. 2a)
PMID:32690472 · one of two readings recorded this
Calcidiol (25-hydroxyvitamin D), change
increases, p = 0.0122
calcidiol (estimated difference 3.96 (95% CI 0.88, 7.04) μg/L; p = 0.0122)
PMID:32823606 · one of two readings recorded this
Change in maternal RBC DHA (wt% TFA), Visit 1 to Visit 4
increases, p = 0.0001, n = 141
the mean change from Visit 1 to Visit 4 was significantly greater in the MMS group compared with the control group, with an estimated treatment difference of 0.96 (95% CI 0.61, 1.31) (p < 0.0001)
PMID:32823606 · one of two readings recorded this
Delivery complications
no effect
a higher proportion of subjects in the control group compared with the MMS group experienced delivery complications (16 (23.2%) vs. eight (12.9%) subjects, respectively)
PMID:32823606 · one of two readings recorded this
Induced labor
no effect
or had an induced labor (13 (18.8%) vs. nine (14.5%) subjects)
PMID:32823606 · one of two readings recorded this
Infant bone density within 10 days after delivery
decreases, p = 0.0486
bone density in m2 (borderline significantly greater in the control group, p = 0.0486)
PMID:32823606 · one of two readings recorded this
Infant subscapular skinfold thickness at delivery
increases, p = 0.0292
subscapular skinfold thickness (thicker in the MMS group, p = 0.0292)
PMID:32823606 · one of two readings recorded this
Maternal RBC DHA/TFA ratio, change
increases, p = 0.0001
maternal RBC DHA/TFA ratio (estimated difference 0.01 (95% CI 0.006, 0.013); p < 0.0001)
PMID:32823606 · one of two readings recorded this
Maternal RBC DHA, women at lower ranges, change vs Visit 1
increases
compared to those in the control group (increase of 0.2% at Visit 3 and 0.5% at Visit 4 vs. Visit 1)
PMID:32823606 · one of two readings recorded this
Maternal RBC DHA, women at lower ranges, change vs Visit 1
increases
compared to those in the control group (increase of 0.2% at Visit 3 and 0.5% at Visit 4 vs. Visit 1)
PMID:32823606 · one of two readings recorded this
Maternal RBC DHA, women at lower ranges, change vs Visit 1
increases
RBC DHA levels in women at the lower ranges increased by a greater extent in the MMS group (1.1% at Visit 3 and 1.6% at Visit 4 vs. Visit 1)
PMID:32823606 · one of two readings recorded this
Maternal RBC DHA, women at lower ranges, change vs Visit 1
increases
RBC DHA levels in women at the lower ranges increased by a greater extent in the MMS group (1.1% at Visit 3 and 1.6% at Visit 4 vs. Visit 1)
PMID:32823606 · one of two readings recorded this
maternal red blood cell omega-3 index (EPA plus DHA, % of RBC fatty acids, gas chromatography) and RBC DHA wt% of total fatty acids, pregnant women, supplement from gestational week 13-15 to delivery
increases, omega-3 index estimated difference 1.00 (95% CI 0.64, 1.37)
Not recorded as a finding: the intervention held more than the compound
Significant differences were observed in favor of MMS for maternal RBC DHA/TFA ratio (estimated difference 0.01 (95% CI 0.006, 0.013); p < 0.0001), omega-3 index (estimated difference 1.00 (95% CI 0.64, 1.37); p < 0.0001), and calcidiol (estimated difference 3.96 (95% CI 0.88, 7.04) μg/L; p = 0.0122) (and Table 2).
PMID:32823606 · one of two readings recorded this
maternal red blood cell omega-3 index (EPA plus DHA, % of RBC fatty acids, gas chromatography), plus RBC DHA wt% (primary), DHA/TFA ratio and calcidiol
increases, omega-3 index estimated difference 1.00 (95% CI 0.64, 1.37)
Not recorded as a finding: the intervention held more than the compound
Significant differences were observed in favor of MMS for maternal RBC DHA/TFA ratio (estimated difference 0.01 (95% CI 0.006, 0.013); p < 0.0001), omega-3 index (estimated difference 1.00 (95% CI 0.64, 1.37); p < 0.0001), and calcidiol (estimated difference 3.96 (95% CI 0.88, 7.04) μg/L; p = 0.0122) (and Table 2).
PMID:32823606 · one of two readings recorded this
Omega-3 index (RBC EPA + DHA), change
increases, p = 0.0001
omega-3 index (estimated difference 1.00 (95% CI 0.64, 1.37); p < 0.0001)
PMID:32823606 · one of two readings recorded this
Other infant anthropometric variables at delivery
no effect
infant variables were comparable between groups, with no statistically significant differences
PMID:32823606 · one of two readings recorded this
Other secondary maternal endpoints (RBC TFA, RBC EPA, GSH/GSSG ratio, ROMs, 8-isoprostane)
no effect
were comparable between groups, albeit slightly higher in the MMS group, with no significant differences
PMID:32823606 · one of two readings recorded this
Age at start of complementary feeding
no effect
The age at which complementary feeding started was similar across groups (DHA vs. Placebo, mean ± SD: 5.4 ± 0.67 vs. 5.3 ± 0.83 months)
PMID:33023067 · one of two readings recorded this
Compliance with supplement
no effect
mean ± SD compliance did not differ by group (DHA: 93.0 ± 10.1; Placebo: 92.7 ± 10.7)
PMID:33023067 · one of two readings recorded this
infant development quotient at 12 months, Developmental Assessment Scale for Indian Infants (DASII, Indian modification of Bayley Scales); mothers dosed 400 mg/d algal DHA vs placebo, outcome in offspring
DQ 96.6 vs 97.1; mean difference (placebo minus DHA) 0.46 (95% CI -1.23, 2.14), p = 0.6
Not recorded as a finding: this platform holds no node for the endpoint
The DQ score (mean ± SD) at 12 months for the DHA and placebo groups was 96.6 ± 12.2 and 97.1 ± 13.0, respectively, and the mean difference (placebo minus DHA) was 0.46 (95% CI: −1.23, 2.14; p = 0.60).
PMID:33023067 · one of two readings recorded this
infant development quotient at 12 months, Developmental Assessment Scale for Indian Infants (DASII); mothers dosed 400 mg/d algal DHA in pregnancy and lactation, outcome measured in offspring
mean difference (placebo minus DHA) 0.46 (95% CI -1.23, 2.14), p = 0.6, n = 863
Not recorded as a finding: this platform holds no node for the endpoint
The DQ score (mean ± SD) at 12 months for the DHA and placebo groups was 96.6 ± 12.2 and 97.1 ± 13.0, respectively, and the mean difference (placebo minus DHA) was 0.46 (95% CI: −1.23, 2.14; p = 0.60).
PMID:33023067 · one of two readings recorded this
Infant development quotient at 12 months, interaction by child gender
modulates, p = 0.013
The p-value for interaction was significant for gender of the child (p = 0.013)
PMID:33023067 · one of two readings recorded this
Infant development quotient at 12 months, other prespecified subgroups
no effect
The mean DQ score did not differ significantly across mother’s age group, BMI, gravida, gestation age at delivery, compliance rate, duration of supplementation, physical activity
PMID:33023067 · one of two readings recorded this
Infant development quotient at 12 months, per protocol analysis
no effect
The per protocol analysis also showed no difference in 12-month DQ scores between the two groups (Table S3)
PMID:33023067 · one of two readings recorded this
Infant development quotient (DASII) at 12 months, female children
decreases
However, the mean DQ score for female child was higher in placebo as compared to DHA [mean difference (placebo− DHA) (95% CI): 2.74 (0.40, 5.09)]
PMID:33023067 · one of two readings recorded this
Infant development quotient (DASII) at 12 months
no effect, p = 0.6, n = 863
The DQ score (mean ± SD) at 12 months for the DHA and placebo groups was 96.6 ± 12.2 and 97.1 ± 13.0, respectively, and the mean difference (placebo minus DHA) was 0.46 (95% CI: −1.23, 2.14; p = 0.60)
PMID:33023067 · one of two readings recorded this
Infant motor and mental scores at 12 months
no effect
The motor and mental scores also did not differ significantly across the groups at 12 months (Table 5)
PMID:33023067 · one of two readings recorded this
Initiation of breastfeeding within 1 h
no effect
Initiation of breastfeeding in 1 h did not differ across groups (DHA vs. Placebo: 79.9% vs. 81.7%)
PMID:33023067 · one of two readings recorded this
Live births proportion
no effect
The proportion of live births was similar across both the groups (DHA vs. Placebo: 94.1% vs. 94.3%)
PMID:33023067 · one of two readings recorded this
Maternal RBC DHA change over intervention, DHA group
increases, p = 0.001
in the DHA group, concentrations increased by 1.04 (0.86, 1.23) mol % of fatty acid, paired t-test, p < 0.001
PMID:33023067 · one of two readings recorded this
Maternal RBC DHA concentration at baseline
no effect
were not different between the groups at baseline (DHA; 0.86 ± 0.78, Placebo: 0.88 ± 0.71)
PMID:33023067 · one of two readings recorded this
Maternal RBC DHA concentration at delivery
increases, p = 0.001
The maternal RBC DHA concentrations (mol % of fatty acid) (mean ± SD) were not different between the groups at baseline (DHA; 0.86 ± 0.78, Placebo: 0.88 ± 0.71) but significantly higher in the DHA group compared to placebo group at delivery (DHA: 1.94 ± 1.42, Placebo: 0.84 ± 0.56; p < 0.001)
PMID:33023067 · one of two readings recorded this
birth weight
no effect, p = 0.54
There were no significant differences between DHA and placebo groups for mean birth weight (2750.6 ± 421.5 vs. 2768.2 ± 436.6 g, p = 0.54), birth length (47.3 ± 2.0 vs. 47.5 ± 2.0 cm, p = 0.13), or head circumference (33.7 ± 1.4 vs. 33.8 ± 1.4 cm, p = 0.15).
PMID:33668849 · one of two readings recorded this
APGAR score at 1 and 5 minutes
no effect
Not recorded as a finding: No outcome node exists for APGAR score.
The APGAR scores at 1 min and 5 min were similar between the groups.
PMID:33668849 · one of two readings recorded this
birth length
no effect, p = 0.13
There were no significant differences between DHA and placebo groups for mean birth weight (2750.6 ± 421.5 vs. 2768.2 ± 436.6 g, p = 0.54), birth length (47.3 ± 2.0 vs. 47.5 ± 2.0 cm, p = 0.13), or head circumference (33.7 ± 1.4 vs. 33.8 ± 1.4 cm, p = 0.15).
PMID:33668849 · one of two readings recorded this
compliance rate
Compliance was high in both groups (DHA: 88.5% and placebo: 87.1%).
PMID:33668849 · one of two readings recorded this
DHA effect on birth size across subgroups (heterogeneity)
no effect, p = 0.007
The effect of DHA on the birth size (i.e., weight, length, and head circumference) did not differ across any of the subgroups examined (p = 0.007, p-value adjusted for multiplicity using Bonferroni correction).
PMID:33668849 · one of two readings recorded this
gestational age at delivery
no effect, p = 0.54
Gestational age at delivery was similar between DHA and placebo groups (DHA vs. placebo: 38.8 ±1.7 vs. 38.8 ± 1.7 wk, p = 0.54).
PMID:33668849 · one of two readings recorded this
head circumference
no effect, p = 0.15
There were no significant differences between DHA and placebo groups for mean birth weight (2750.6 ± 421.5 vs. 2768.2 ± 436.6 g, p = 0.54), birth length (47.3 ± 2.0 vs. 47.5 ± 2.0 cm, p = 0.13), or head circumference (33.7 ± 1.4 vs. 33.8 ± 1.4 cm, p = 0.15).
PMID:33668849 · one of two readings recorded this
live birth count
There were 450 (94.1%) and 452 (94.3%) live births in the DHA (n = 478) and placebo (n = 479) groups, respectively.
PMID:33668849 · one of two readings recorded this
live birth rate
There were 450 (94.1%) and 452 (94.3%) live births in the DHA (n = 478) and placebo (n = 479) groups, respectively.
PMID:33668849 · one of two readings recorded this
male sex of offspring (count)
There were 230 (52.3%) and 235 (53.4%) male children in the DHA and placebo groups, respectively, and percentages were calculated based on 440 (DHA) and 440 (placebo) analyzed neonates.
PMID:33668849 · one of two readings recorded this
male sex of offspring (rate)
There were 230 (52.3%) and 235 (53.4%) male children in the DHA and placebo groups, respectively, and percentages were calculated based on 440 (DHA) and 440 (placebo) analyzed neonates.
PMID:33668849 · one of two readings recorded this
maternal plasma DHA level change (baseline to delivery)
increases, p = 0.001
There is an increase in mean DHA level in both the groups from baseline to delivery (DHA 1.20 (0.98, 1.43), p = <0.001; placebo 0.24 (0.11, 0.36), p = 0.0002).
PMID:33668849 · one of two readings recorded this
maternal plasma DHA level change (baseline to delivery)
increases, p = 0.0002
There is an increase in mean DHA level in both the groups from baseline to delivery (DHA 1.20 (0.98, 1.43), p = <0.001; placebo 0.24 (0.11, 0.36), p = 0.0002).
PMID:33668849 · one of two readings recorded this
Allocation to control group as predictor of NEC (multivariate CHAID)
decreases, p = 0.002
Multivariate analysis identified that being in the control-group was the strongest predictor for developing NEC (adjusted p = 0.002, Figure 2)
PMID:33671220 · one of two readings recorded this
Apnea in infants older than 29 weeks gestational age as predictor of NEC
increases, p = 0.014
The probability of developing NEC was higher in infants older than 29 weeks of gestational age at birth who presented with apnea (adjusted p = 0.014, Figure 2)
PMID:33671220 · one of two readings recorded this
At least one bleeding entity (IVH grade II or higher, upper GI or pulmonary bleeding)
no effect, p = 0.438
there was no difference between the DHA and control groups in the presence of at least one of the following bleeding entities: periventricular/intraventricular hemorrhage grade ≥ II and upper gastrointestinal tract and/or pulmonary bleeding (68/100 compared with 73/100, p = 0.438)
PMID:33671220 · one of two readings recorded this
Baseline erythrocyte alpha-linolenic acid
increases
The fatty acid profile of erythrocytes collected at the baseline was similar between groups, except that alpha-linolenic acid was higher in the DHA-group (Table 5)
PMID:33671220 · one of two readings recorded this
Confirmed necrotizing enterocolitis (Bell stage IIa or greater)
decreases, p = 0.007
Confirmed NEC was lower in infants from the DHA-group compared with the control-group (0/100 vs. 7/100, p = 0.007) with a RR of 0.93 (95% CI 0.881 to 0.981, p = 0.008)
PMID:33671220 · one of two readings recorded this
Confirmed necrotizing enterocolitis, risk difference
decreases
there was a risk difference of −7% (95% CI −12.00 to −1.99), and a number needed to treat of 15 (95% CI 8.3 to 50)
PMID:33671220 · one of two readings recorded this
Cumulative arachidonic acid intake from human milk
while the control-group received 0.25 (0.12 to 0.38) mg/kg/day and 0.35 (0.18 to 0.63) mg/kg/day, respectively
PMID:33671220 · one of two readings recorded this
Cumulative arachidonic acid intake from human milk
displayed a median of 0.31 (0.12 to 1.13) mg/kg/day and 0.84 (0.35 to 2.52) mg/kg/day in the DHA-group
PMID:33671220 · one of two readings recorded this
Cumulative DHA intake from human milk
while the control-group received 0.25 (0.12 to 0.38) mg/kg/day and 0.35 (0.18 to 0.63) mg/kg/day, respectively
PMID:33671220 · one of two readings recorded this
Cumulative DHA intake from human milk
displayed a median of 0.31 (0.12 to 1.13) mg/kg/day and 0.84 (0.35 to 2.52) mg/kg/day in the DHA-group
PMID:33671220 · one of two readings recorded this
death (per-protocol and intent-to-treat mortality during the study), count
no effect, 3/105 vs 8/109, RR = 0.954 (95% CI 0.896 to 1.015), p = 0.119
Not recorded as a finding: agentless/within-hospital mortality not clearly 'death before discharge' and sentence reports a non-significant RR; no clean two-sided statement for the node
Likewise, in the intent-to-treat analysis, mortality was not different between the DHA-group and control-group (3/105 vs. 8/109, p = 0.119) with an RR = 0.954 for infants in the DHA-group (95% CI 0.896 to 1.015).
PMID:33671220 · one of two readings recorded this
Death
no effect, p = 0.106
The per protocol analysis showed no difference in death between the DHA and control groups (1/100 compared to 5/100, one-sided hypothesis p = 0.106), with an RR of 0.960 for the DHA-group (95% CI 0.914 to 1.008)
PMID:33671220 · one of two readings recorded this
EPA and DHA content of human milk received
decreases
The human milk received by the infants in the DHA-group contained less eicosapentaenoic acid and DHA than the human milk received by the infants in the control-group
PMID:33671220 · one of two readings recorded this
Gestational age as predictor of NEC (multivariate CHAID)
unclear, p = 0.043
Among infants in the control-group, the best predictor for developing NEC was the gestational age (adjusted p = 0.043, Figure 2)
PMID:33671220 · one of two readings recorded this
Median number of bleeding events
no effect, p = 0.814
The median of the bleeding events was similar (1 (1, 2) vs. 1 (1, 2), p = 0.814)
PMID:33671220 · one of two readings recorded this
mortality during the hospital stay, per protocol
no effect, 1/100 vs 5/100, RR 0.960 (95% CI 0.914 to 1.008), p = 0.106
Not recorded as a finding: all-cause-mortality node requires the follow-up horizon recorded with each finding and the sentence names none; the result was also not significant
The per protocol analysis showed no difference in death between the DHA and control groups (1/100 compared to 5/100, one-sided hypothesis p = 0.106), with an RR of 0.960 for the DHA-group (95% CI 0.914 to 1.008).
PMID:33671220 · one of two readings recorded this
Mortality
no effect, p = 0.119
mortality was not different between the DHA-group and control-group (3/105 vs. 8/109, p = 0.119) with an RR = 0.954 for infants in the DHA-group (95% CI 0.896 to 1.015)
PMID:33671220 · one of two readings recorded this
Number needed to treat to prevent one confirmed NEC
there was a risk difference of −7% (95% CI −12.00 to −1.99), and a number needed to treat of 15 (95% CI 8.3 to 50)
PMID:33671220 · one of two readings recorded this
Periventricular/intraventricular hemorrhage grade II or higher
no effect, p = 0.669
Periventricular/intraventricular hemorrhage grade ≥ II was the most common type of bleeding (57% in the DHA-group vs. 54% in the control-group, p = 0.669)
PMID:33671220 · one of two readings recorded this
Platelet count
no effect, p = 0.647
The median (minimum, maximum) of platelet counts was not different between the DHA and control groups at the baseline and after the intervention (196,000 mm3 (107,000, 464,000) vs. 182,000 (103,000, 473,000), p = 0.647 and 345,000 mm3 (120,000, 598,000) vs. 347,000 (131,000, 776,000), p = 0.884, respectively)
PMID:33671220 · one of two readings recorded this
Post-enteral feeding time to diagnosis of confirmed NEC
The post-enteral feeding time to diagnosis of confirmed NEC was 4 (0, 23) days
PMID:33671220 · one of two readings recorded this
Postnatal age at diagnosis of confirmed NEC
The median (minimum, maximum) postnatal age at diagnosis of confirmed NEC was 26 (6, 29) days
PMID:33671220 · one of two readings recorded this
Treatment failure (confirmed NEC or related failure)
decreases, p = 0.031
a lower level of treatment failure in the DHA-group compared with the control-group (6/105 (6%) vs. 16/109 (15%); p = 0.031) with an RR of 0.905 (95% CI 0.826 to 0.991)
PMID:33671220 · one of two readings recorded this
Monocyte ATP-linked oxygen consumption
decreases, p = 0.05
28 days of flaxseed-oil supplementation reduced ATP-linked oxygen consumption (0.75-fold; P < 0.05) and increased spare respiratory capacity (1.4-fold; P < 0.05) in monocytes
PMID:34293124 · one of two readings recorded this
Monocyte spare respiratory capacity
increases, p = 0.05
28 days of flaxseed-oil supplementation reduced ATP-linked oxygen consumption (0.75-fold; P < 0.05) and increased spare respiratory capacity (1.4-fold; P < 0.05) in monocytes
PMID:34293124 · one of two readings recorded this
plasma adiponectin after 28 days of DHA-rich fish oil, versus baseline; the trial's comparison arm was ALA-rich flaxseed oil
increases, 1.1-fold
Not recorded as a finding: the comparison was against another active treatment
Neither supplement altered plasma cytokines; however, adiponectin was increased (1.1-fold; P < 0.05) at the end of the fish-oil phase.
PMID:34293124 · one of two readings recorded this
plasma adiponectin concentration (and plasma oxylipins, cytokines, monocyte bioenergetics) after 4 g/day DHA-rich fish oil versus 4 g/day ALA-rich flaxseed oil, crossover, abstract only
increases, 1.1-fold versus baseline visit
Not recorded as a finding: the comparison was against another active treatment
Neither supplement altered plasma cytokines; however, adiponectin was increased (1.1-fold; P < 0.05) at the end of the fish-oil phase.
PMID:34293124 · one of two readings recorded this
Plasma adiponectin
increases, p = 0.05
adiponectin was increased (1.1-fold; P < 0.05) at the end of the fish-oil phase
PMID:34293124 · one of two readings recorded this
Plasma cytokines
no effect
Neither supplement altered plasma cytokines
PMID:34293124 · one of two readings recorded this
Plasma DHA-derived oxylipins
increases, p = 0.001
there were higher plasma levels of nearly all oxylipins derived from DHA (3.8-fold overall; P < 0.001) and EPA (2.7-fold overall; P < 0.05) after 28 days of fish-oil supplementation
PMID:34293124 · one of two readings recorded this
Plasma EPA-derived oxylipins
increases, p = 0.05
there were higher plasma levels of nearly all oxylipins derived from DHA (3.8-fold overall; P < 0.001) and EPA (2.7-fold overall; P < 0.05) after 28 days of fish-oil supplementation
PMID:34293124 · one of two readings recorded this
Plasma oxylipins
no effect
while there were no changes to oxylipins after flaxseed-oil supplementation
PMID:34293124 · one of two readings recorded this
DHA (and fucoxanthin) productivity of cold-adapted Tisochrysis lutea microalgal culture
decreases, DHA productivity fell 85% (biomass -92%, fucoxanthin -98%) in the original strain when culture temperature was reduced from 30 degC to 15 degC
Not recorded as a finding: the compound is what was measured, not what was given
For the original strain the productivity of biomass, fucoxanthin, and DHA decreased by 92 %, 98 % and 85 % respectively when decreasing the temperature from 30 °C to 15 °C.
PMID:34500104 · one of two readings recorded this
DHA productivity (percentage of biomass) in cultures of the microalga Tisochrysis lutea grown at different temperatures
no effect
Not recorded as a finding: the compound is what was measured, not what was given
In the sorted cold-adapted 'winter strain', biomass, fucoxanthin, and DHA productivities were similar to those at 30 °C.
PMID:34500104 · one of two readings recorded this
Global and subscale cognitive development (Verbal, Perceptual-Performance, Quantitative, Memory, Motor, General Cognitive) on the McCarthy Scales of Children's Abilities (MSCA) at 5 years
no effect, n = 622
Not recorded as a finding: this platform holds no node for the endpoint
There were no significant differences in offspring MSCA scores at 5 years by intervention group (Table 1), and maternal FADS2 SNPs rs174602 or rs174575 were not associated with children’s MSCA scores at 5 years (Table 2).
PMID:34543890 · one of two readings recorded this
MSCA Memory score × FADS2 rs174602 interaction
p = 0.01
We found evidence of an interaction between the intervention and maternal SNP rs174602 in the Quantitative (p=0.02) and Memory scales (p=0.01) of the MSCA test (Table 3).
PMID:34543890 · one of two readings recorded this
MSCA Memory score
increases
Similarly, for Memory scores, among offspring of T homozygotes, those who received the intervention had scored on average 4.3 points higher, which also represents a difference of 0.6 SD.
PMID:34543890 · one of two readings recorded this
MSCA Memory score
increases
Similarly, for Memory scores, among offspring of T homozygotes, those who received the intervention had scored on average 4.3 points higher, which also represents a difference of 0.6 SD.
PMID:34543890 · one of two readings recorded this
MSCA Quantitative score × FADS2 rs174602 interaction
p = 0.02
We found evidence of an interaction between the intervention and maternal SNP rs174602 in the Quantitative (p=0.02) and Memory scales (p=0.01) of the MSCA test (Table 3).
PMID:34543890 · one of two readings recorded this
MSCA Quantitative score
increases
For Quantitative scores, among children whose mothers were homozygotes for the minor allele T, those in the intervention group had on average 3.5 higher scores than those in the control, which is equivalent to a difference of 0.6 SD.
PMID:34543890 · one of two readings recorded this
MSCA Quantitative score
increases
For Quantitative scores, among children whose mothers were homozygotes for the minor allele T, those in the intervention group had on average 3.5 higher scores than those in the control, which is equivalent to a difference of 0.6 SD.
PMID:34543890 · one of two readings recorded this
offspring global cognitive development at 5 years, McCarthy Scales of Children's Abilities (MSCA) scores, by randomised prenatal DHA group
no effect
Not recorded as a finding: this platform holds no node for the endpoint
There were no significant differences in offspring MSCA scores at 5 years by intervention group (Table 1), and maternal FADS2 SNPs rs174602 or rs174575 were not associated with children's MSCA scores at 5 years (Table 2).
PMID:34543890 · one of two readings recorded this
Sources cited
9 papers
- Subject
- all-cis-docosa-4,7,10,13,16,19-hexaenoic acid
- Findings
- 10
- Papers
- 9
Accumulation of newly synthesized docosahexaenoic acid plays an essential role in heart regeneration.record2026PMID:408513701 finding
Impact of Omega-3 Fatty Acid Docosahexaenoic Acid Supplementation in Individuals During Pregnancy on Neurodevelopment and Growth of Offspring: Systematic Review and Meta-Analysis.record2026PMID:424943001 finding
NRF1 is upregulated by docosahexaenoic acid to ameliorate MASH through the inhibition of ER stress.record2026PMID:415453422 findings
Docosahexaenoic Acid and Its Metabolites Protect against Ozone-induced Pulmonary Inflammation.record2025PMID:402086401 finding
Safety and efficacy of docosahexaenoic acid supplementation during neoadjuvant breast cancer therapy: Findings from the phase II, double-blind, randomized controlled DHA-WIN trial.record2025PMID:404908461 finding
The effects of docosahexaenoic acid (DHA) on plasma cytokines, oxylipins, and tumor-infiltrating lymphocytes from women with breast cancer undergoing neoadjuvant chemotherapy in the DHA-WIN trial.record2025PMID:406517091 finding
Effects of dietary eicosapentaenoic acid and docosahexaenoic acid supplementation on metabolic syndrome: A systematic review and meta-analysis of data from 33 randomized controlled trials.record2021PMID:342292581 finding
Efficacy of Docosahexaenoic Acid for the Prevention of Necrotizing Enterocolitis in Preterm Infants: A Randomized Clinical Trial.record2021PMID:336712201 finding
Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid.record2014PMID:248280441 finding
Other names
15 names
Resolves to: all-cis-docosa-4,7,10,13,16,19-hexaenoic acid
- Also called
- (4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoic acid22:6-4, 7,10,13,16,1922:6(n-3)4,7,10,13,16,19-docosahexaenoic acid4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acidall-cis-4,7,10,13,16,19-docosahexaenoic acidall-cis-DHAC22:6n-3,6,9,12,15,18cervonic acidDHADoconexentDOCOSA-4,7,10,13,16,19-HEXAENOIC ACIDDocosahexaenoic acidFA 22:6
- Systematic name
- (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid