(9Z,12Z,15Z)-octadecatrienoyl-CoA

1. Linolenoyl-CoA hydrolase

Catalysed by ACOT7, BAAT, ACOT1cytosolOne of 9 routes

1. (9Z,12Z,15Z)-octadecatrienoyl-CoA + H2O = S-(9Z,12Z,15Z-octadecatrienoyl)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Catalysed by NUDT19

1. Fatty Acid Beta Oxidation (C18:3->C16:3), Mitochondrial

Catalysed by HADHA, ACADVL, HADHBmitochondrial matrix

1. Linolenoyl-CoA hydrolase

Catalysed by ACOT7, BAAT, ACOT1cytosol

1. acyl-CoA pool formation and breakdown

No catalyst recordedcytosol

1. fatty acyl-CoA desaturase (N-C18:2CoA -> N-C18:3CoA)

Catalysed by FADS2cytosolOne of 3 routes

1. (9Z,12Z,15Z)-octadecatrienoyl-CoA + malonyl-CoA + H(+) = (11Z,14Z,17Z)-3-oxoeicosatrienoyl-CoA + CO2 + CoA

Catalysed by ELOVL7, ELOVL6, ELOVL3, ELOVL5

1. (9Z,12Z,15Z)-octadecatrienoyl-CoA + cholesterol = (9Z,12Z,15Z-octadecatrienoyl)-cholesterol + CoA

Catalysed by SOAT2

1. Linolenoyl-CoA hydrolase
2. Carnitine O-Palmitoyltransferase

Catalysed by ACOT7, BAAT, ACOT1, CPT1A and 2 morecytosolOne of 245 routes

1. acyl-CoA pool formation and breakdown
2. an acyl-CoA + H2O = an acyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Catalysed by NUDT19, FITM2, NUDT8cytosol