15-oxoprostaglandin E1

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

66 compounds within 3 steps: 1 in 1, 5 in 2, 60 in 3

One step

prostaglandin E1Reach from here →
1. (13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NADP+ 15-oxidoreductase
Catalysed by CBR3, CBR1, DHRS4cytosol

Two steps

2,4-dinitrophenyl-S-glutathioneReach from here →
1. (13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NADP+ 15-oxidoreductase
2. transport of prostaglandin E1 (cytosol to extracellular)
Catalysed by CBR3, CBR1, DHRS4, SLCO1B1cytosol, extracellular spaceOne of 2 routes
(S)-lactateReach from here →
1. (13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NADP+ 15-oxidoreductase
2. prostaglandin E1(out) + 2 (S)-lactate(in) = prostaglandin E1(in) + 2 (S)-lactate(out)
Catalysed by CBR3, CBR1, DHRS4, SLCO2A1cytosol, inner side of the membrane, outer side of the membrane

Three steps

One of 2 routes

CHEBI:16856Reach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO2A1cytosol, extracellular spaceOne of 2 routes

prostaglandin F1Reach from here →

Catalysed by CBR3, CBR1, DHRS4, DHRS1cytosol

prostaglandin H1Reach from here →

Catalysed by CBR3, CBR1, DHRS4, PTGES and 2 morecytosolOne of 2 routes

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1 and 2 morecytosol, extracellular spaceOne of 4 routes

(11S,15S)-dihydroxy-14(R)-S-glutathionyl-(5Z,8Z,12E)-eicosatrienoateReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO2A1 and 21 morecytosol, extracellular spaceOne of 4 routes

prostaglandin E3Reach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1cytosol, extracellular spaceOne of 6 routes

prostaglandin A2Reach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1cytosol, extracellular spaceOne of 4 routes

prostaglandin B1Reach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1cytosol, extracellular spaceOne of 4 routes

leukotriene F4Reach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1cytosol, extracellular spaceOne of 4 routes

acetylcholineReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1 and 1 morecytosol, extracellular spaceOne of 4 routes

pyruvateReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO2A1 and 5 morecytosol, inner side of the membrane, outer side of the membrane

CHEBI:15650Reach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1cytosol, extracellular spaceOne of 4 routes

bromideReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO2A1 and 17 morecytosol, extracellular spaceOne of 2 routes

lithocholic acidReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1 and 2 morecytosol, extracellular spaceOne of 4 routes

N-[(S)-lactoyl]-L-phenylalanineReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO2A1 and 1 morecytosol, inner side of the membrane, outer side of the membrane

bilirubin IXalphaReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1 and 2 morecytosol, extracellular spaceOne of 4 routes

taurolithocholateReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1 and 2 morecytosol, extracellular spaceOne of 4 routes

CHEBI:17208Reach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO2A1cytosol, extracellular space

homocysteineReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO2A1cytosol, extracellular space

L-cysteineReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO2A1cytosol, extracellular space

urateReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO2A1 and 2 morecytosol, inner side of the membrane, outer side of the membrane

(S)-lactoyl-AMPReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO2A1 and 2 morecytosol, inner side of the membrane, outer side of the membrane

(S)-lactoyl-CoAReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO2A1 and 1 morecytosol, inner side of the membrane, outer side of the membrane

5(S)-HETEReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO2A1 and 9 morecytosol, extracellular spaceOne of 2 routes

CHEBI:28666Reach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1cytosol, extracellular spaceOne of 4 routes

glycocholateReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1 and 2 morecytosol, extracellular spaceOne of 4 routes

cholateReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1 and 2 morecytosol, extracellular spaceOne of 4 routes

(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1cytosol, extracellular spaceOne of 4 routes

serotoninReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1 and 2 morecytosol, extracellular spaceOne of 4 routes

chenodeoxycholateReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1 and 2 morecytosol, extracellular spaceOne of 2 routes

taurocholateReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1 and 2 morecytosol, extracellular spaceOne of 4 routes

glycolithocholic acidReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1 and 2 morecytosol, extracellular spaceOne of 4 routes

gamma-Glu-AlaReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO2A1 and 6 morecytosol, extracellular space

3,3',5-triiodo-L-thyronineReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1 and 2 morecytosol, extracellular spaceOne of 4 routes

prostaglandin I2Reach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1cytosol, extracellular spaceOne of 4 routes

prostaglandin F2alphaReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1cytosol, extracellular spaceOne of 6 routes

prostaglandin H2Reach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1cytosol, extracellular spaceOne of 6 routes

prostaglandin D2Reach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1cytosol, extracellular spaceOne of 6 routes

(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoateReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO2A1 and 9 morecytosol, extracellular space

leukotriene A4Reach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1cytosol, extracellular spaceOne of 4 routes

(R)-S-lactoylglutathioneReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO2A1 and 2 morecytosol, extracellular spaceOne of 2 routes

S-formylglutathioneReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO2A1 and 6 morecytosol, extracellular space

dehydroepiandrosterone 3-sulfateReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1cytosol, extracellular spaceOne of 2 routes

leukotriene C4Reach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1cytosol, extracellular spaceOne of 6 routes

glutathione disulfideReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO2A1 and 9 morecytosol, extracellular spaceOne of 13 routes

taurolithocholate 3-sulfateReach from here →

Catalysed by CBR3, CBR1, DHRS4, SLCO1B1 and 2 morecytosol, extracellular spaceOne of 4 routes