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Proteins/UNIPROT:Q96LJ7
NADPH-dependent oxidoreductase which catalyzes the reduction of steroids (estrone, androstene-3,17-dione and cortisone) as well as prostaglandin E1, isatin and xenobiotics in vitro. May have a role in steroid and/or xenobiotic metabolism..
Function from UniProtKB (Q96LJ7), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
29 statements
29 statements · 3 reference databases · Subject: DHRS1 · Sources: Bgee, Hetionet, Rhea
4 reactions
testosterone+NADP(3-)androst-4-ene-3,17-dione+NADPH(4-)+hydron
Catalysed by AKR1B15 or HSD17B1 or AKR1C4 or HSD17B3 or AKR1C3 or AKR1C2 or AKR1C1 or DHRS1
Reaction pageRight to leftBalanced
Rhea RHEA:14981CC BY 4.0Reference data
3 names
Resolves to: DHRS1
Catalysed by DHRS1
Reaction pageRight to leftBalanced
Rhea RHEA:16705CC BY 4.0Reference data
CHEBI:27539+NADPH(4-)+hydronCHEBI:28536+NADP(3-)
Reaction pageLeft to rightBalanced
Rhea RHEA:68608CC BY 4.0Reference data
prostaglandin E1+NADPH(4-)+hydronprostaglandin F1+NADP(3-)
Catalysed by DHRS1
Reaction pageLeft to rightBalanced
Rhea RHEA:68612CC BY 4.0Reference data