13-cis-retinal

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

99 compounds within 3 steps: 3 in 1, 19 in 2, 77 in 3

One step

all-trans-retinoic acidReach from here →
1. retinal dehydrogenase (13-cis-retinal)
Catalysed by ALDH1A2, ALDH1A1endoplasmic reticulum
all-trans-retinalReach from here →
1. 13-cis-retinal to retinal conversion
No catalyst recordedcytosolOne of 2 routes
13-cis-retinolReach from here →
1. retinol dehydrogenase (13-cis-retinal)
Catalysed by RDH5cytosolOne of 3 routes

Two steps

2-hydroxybutyric acidReach from here →
1. retinal dehydrogenase (13-cis-retinal)
2. transport of 2-hydroxybutyrate and retinoate (cytosol to extracellular)
Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5 and 2 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes
all-trans-4-hydroxyretinoateReach from here →
1. retinal dehydrogenase (13-cis-retinal)
2. cytochrome P450 (retinoate)
Catalysed by ALDH1A2, ALDH1A1, CYP26A1

Three steps

(S)-3-hydroxybutanoateReach from here →
Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5 and 1 moreendoplasmic reticulum, extracellular space, cytosol
AReach from here →

endoplasmic reticulum, cytosol

One of 3 routes

acetoacetateReach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5endoplasmic reticulum, extracellular space, cytosolOne of 2 routes

13-cis-retinyl tetradecanoateReach from here →

Catalysed by RDH5, AWAT2cytosol

13-cis-retinyl hexadecanoateReach from here →

Catalysed by RDH5, DGAT1cytosol

all-trans-retinoyl-1-O-(beta-D-glucuronate)Reach from here →

Catalysed by ALDH1A2, ALDH1A1, UGT1A1, UGT1A10 and 1 moreendoplasmic reticulum

all-trans-18-hydroxyretinoateReach from here →

Catalysed by ALDH1A2, ALDH1A1, CYP1A1, CYP1A2 and 23 moreendoplasmic reticulum, cytosolOne of 2 routes

pyruvateReach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5 and 4 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes

11-cis-retinalReach from here →

Catalysed by RBP1, RBP2cytosol

(R)-3-hydroxybutyric acidReach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5 and 2 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes

all-trans-retinolReach from here →

Catalysed by AKR1B15, AKR1B10, DHRS3, AKR1B1 and 7 morecytosol

13-cis-retinyl esterReach from here →

Catalysed by RDH5, AWAT2cytosol

acetateReach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5 and 1 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes

formic acidReach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5endoplasmic reticulum, extracellular space, cytosolOne of 2 routes

propionic acidReach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5 and 1 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes

butyric acidReach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5endoplasmic reticulum, extracellular space, cytosolOne of 2 routes

all-trans-retinoateReach from here →

Catalysed by ALDH1A2, ALDH1A1, ALDH1B1, ALDH1A3 and 1 morecytosolOne of 2 routes

(S)-lactic acidReach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5 and 4 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes

9-cis-retinalReach from here →

Catalysed by RBP1, RBP2cytosol, endoplasmic reticulumOne of 2 routes

Catalysed by AKR1B15, AKR1B10, DHRS3, AKR1B1 and 8 more

cytosol

all-trans-3,4-didehydroretinolReach from here →

Catalysed by AKR1B15, AKR1B10, DHRS3, AKR1B1 and 8 morecytosol

all-trans-4-hydroxyretinolReach from here →

Catalysed by AKR1B15, AKR1B10, DHRS3, AKR1B1 and 8 morecytosol

prostaglandin E3Reach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5 and 4 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes

prostaglandin A2Reach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5 and 4 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes

prostaglandin J2Reach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5 and 4 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes

15-oxoprostaglandin F2alphaReach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5 and 4 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes

all-trans-4-oxoretinoateReach from here →

Catalysed by ALDH1A2, ALDH1A1, CYP26A1, CYP26B1endoplasmic reticulum, cytosolOne of 3 routes

N-acetylcadaverineReach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5 and 2 moreendoplasmic reticulum, extracellular space, cytosol

all-trans-retinyl tetradecanoateReach from here →

Catalysed by AKR1B15, AKR1B10, DHRS3, AKR1B1 and 8 morecytosol

all-trans-4-hydroxy-4-O-(beta-D-glucuronide)-retinoateReach from here →

Catalysed by ALDH1A2, ALDH1A1, CYP26A1, UGT2B7endoplasmic reticulum, cytosol

a phenyl acetateReach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5 and 4 moreendoplasmic reticulum, extracellular space, cytosol

CHEBI:15345Reach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5 and 1 moreendoplasmic reticulum, extracellular space, cytosolOne of 3 routes

acetoneReach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5endoplasmic reticulum, extracellular space, cytosol, mitochondrial matrix

acetylpyruvateReach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5 and 5 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes

propionyl-CoAReach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5 and 4 moreendoplasmic reticulum, extracellular space, cytosolOne of 3 routes

(S)-malateReach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5 and 5 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes

10-formyltetrahydrofolic acidReach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5 and 1 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes

all-trans-3-hydroxyretinolReach from here →

Catalysed by AKR1B15, AKR1B10, DHRS3, AKR1B1 and 8 morecytosol

2-methyl-3-oxopropanoic acidReach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5 and 5 moreendoplasmic reticulum, extracellular space, cytosol, mitochondrial matrix

11-cis-retinolReach from here →

Catalysed by RBP1, RBP2, HSD17B6, RDH16 and 5 morecytosolOne of 6 routes

oxaloacetateReach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5 and 5 moreendoplasmic reticulum, extracellular space, cytosol, mitochondrial matrixOne of 3 routes

N(2)-acetyl-L-ornithineReach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5 and 2 moreendoplasmic reticulum, extracellular space, cytosol

(S)-lactateReach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5 and 9 moreendoplasmic reticulum, extracellular space, cytosol

2-oxobutanoateReach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5 and 6 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes

2-oxoglutaramateReach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5 and 5 moreendoplasmic reticulum, extracellular space, cytosolOne of 2 routes

3-fumarylpyruvateReach from here →

Catalysed by ALDH1A2, ALDH1A1, SLC16A4, SLC16A5 and 5 moreendoplasmic reticulum, extracellular space, cytosol