Compound

all-trans-4-hydroxyretinol

A retinoid that consists of all-trans-retinol having a hydroxy substituent at position 4 on the cyclohexenyl ring.

Definition from ChEBI (CHEBI:132259), read 2026-09-23. CC BY 4.0.

CHEBI:132259ChEBI

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Structure

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A generated conformer of all-trans-4-hydroxyretinol — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound
Formula: C20H30O2
Mass: 302.458 g/mol
Charge: 0
InChIKey: IOELQUUUYMBPSA-RMWYGNQTSA-N
SMILES: CC1=C(/C=C/C(C)=C/C=C/C(C)=C/CO)C(C)(C)CCC1O
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

2 entities

2 entities reached.

0 reported hops2 assembled from the scaffold

What the reference databases state

Chemical structure

all-trans-4-hydroxyretinol has the functional parent all-trans-retinolCompoundChEBI CHEBI:132259Inferred only

Statements

5 statements

5 statements · 2 reference databases · Subject: all-trans-4-hydroxyretinol · Sources: Human-GEM, Rhea

Order

all-trans-4-hydroxyretinol is converted to all-trans-4-hydroxyretinalCompoundHuman-GEM MAR20067Inferred only
all-trans-4-hydroxyretinol is converted to all-trans-4-hydroxyretinalCompoundRhea RHEA:55936Inferred only
all-trans-4-hydroxyretinol is metabolised by ADH1BProteinHuman-GEM MAR20067Inferred only
all-trans-4-hydroxyretinol is metabolised by ADH1BProteinRhea RHEA:55936Inferred only
all-trans-4-hydroxyretinol is metabolised by ADH7ProteinRhea RHEA:55936Inferred only

Reactions

3 reactions

NAD(+)+all-trans-4-hydroxyretinolproton+NADH(2-)+all-trans-4-hydroxyretinal
Catalysed by ADH1B
Reaction pageLeft to rightBalancedEC 1.1.1.1cytosol
Human-GEM MAR20067CC BY 4.0Reference data
all-trans-retinol+2reduced [adrenodoxin]+dioxygen+2hydronall-trans-4-hydroxyretinol+2oxidized [adrenodoxin]+water
Catalysed by CYP27C1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:50300CC BY 4.0Reference data
all-trans-4-hydroxyretinol+NAD(1-)all-trans-4-hydroxyretinal+NADH(2-)+hydron
Catalysed by ADH1B or ADH7
Reaction pageLeft to rightBalanced
Rhea RHEA:55936CC BY 4.0Reference data

Other names

3 names

Resolves to: all-trans-4-hydroxyretinol

Also called: 3-[(1E,3E,5E,7E)-9-hydroxy-3,7-dimethylnona-1,3,5,7-tetraenyl]-2,4,4-trimethylcyclohex-2-en-1-ol4-hydroxy-retinol
Systematic name: 4-hydroxyretinol