Compound

all-trans-retinoate

A retinoate that is the conjugate base of all-trans-retinoic acid.

Definition from ChEBI (CHEBI:35291), read 2026-09-23. CC BY 4.0.

CHEBI:35291ChEBI

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Structure

2D depiction · 3D model shown

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A generated conformer of all-trans-retinoate — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, anion
Formula: C20H27O2
Mass: 299.434 g/mol
Charge: -1
InChIKey: SHGAZHPCJJPHSC-YCNIQYBTSA-M
SMILES: CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C(=O)[O-])C(C)(C)CCC1
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

1 entity

1 entities reached.

0 reported hops1 assembled from the scaffold

UGT2B7ProteinUNIPROT:P16662metabolized byInferred only16 paths16 endpoints

What the reference databases state

Statements

1 statement

1 statement · 1 reference database · Subject: all-trans-retinoate · Sources: Rhea

Order

all-trans-retinoate is metabolised by UGT2B7ProteinRhea RHEA:55768Inferred only

Reactions

8 reactions

all-trans-retinal+dioxygen+waterall-trans-retinoate+hydrogen peroxide+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:22520CC BY 4.0Reference data
all-trans-retinal+NAD(1-)+waterall-trans-retinoate+NADH(2-)+2hydron
Catalysed by ALDH1A2 or ALDH1A1 or ALDH1B1 or ALDH1A3 or HSD17B13
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:42080CC BY 4.0Reference data
all-trans-retinal+reduced [NADPH--hemoprotein reductase]+dioxygenall-trans-retinoate+oxidized [NADPH--hemoprotein reductase]+water+2hydron
Catalysed by CYP1A1 or CYP1A2 or CYP1B1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:42088CC BY 4.0Reference data
all-trans-retinoate+reduced [NADPH--hemoprotein reductase]+dioxygenCHEBI:134185+oxidized [NADPH--hemoprotein reductase]+water+hydron
Catalysed by CYP26A1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:51492CC BY 4.0Reference data
all-trans-retinoate+reduced [NADPH--hemoprotein reductase]+dioxygenall-trans-4-hydroxyretinoate+oxidized [NADPH--hemoprotein reductase]+water+hydron
Catalysed by CYP3A4 or CYP2C8 or CYP3A5 or CYP3A7 or CYP2C18 or CYP26C1 or CYP2W1 or CYP2S1 or CYP26B1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:51984CC BY 4.0Reference data
all-trans-retinoate+UDP-alpha-D-glucuronateall-trans-retinoyl-1-O-(beta-D-glucuronate)+UDP
Catalysed by UGT2B7
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:55768CC BY 4.0Reference data
all-trans-retinoate+reduced [NADPH--hemoprotein reductase]+dioxygenall-trans-18-hydroxyretinoate+oxidized [NADPH--hemoprotein reductase]+water+hydron
Catalysed by CYP26A1 or CYP3A7 or CYP26B1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:55856CC BY 4.0Reference data
all-trans-retinoate+reduced [NADPH--hemoprotein reductase]+dioxygenCHEBI:139183+oxidized [NADPH--hemoprotein reductase]+water+hydron
Catalysed by CYP2S1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:55860CC BY 4.0Reference data

Other names

2 names

Resolves to: all-trans-retinoate

Also called: Retinoate
Systematic name: (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoate