9-cis-retinal

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

42 compounds within 3 steps: 2 in 1, 9 in 2, 31 in 3

One step

all-trans-retinalReach from here →
1. 9-cis-retinal to retinal conversion
No catalyst recordedcytosol
9-cis-retinolReach from here →
1. 9-cis-retinol:NAD+ oxidoreductase
Catalysed by HSD17B6, RDH16, ADH4, RBP3 and 5 morecytosolOne of 2 routes

Two steps

9-cis-retinyl tetradecanoateReach from here →
1. 9-cis-retinol:NAD+ oxidoreductase
2. 9-cis-retinol + tetradecanoyl-CoA = 9-cis-retinyl tetradecanoate + CoA
Catalysed by HSD17B6, RDH16, ADH4, RBP3 and 6 morecytosol
9-cis-retinyl hexadecanoateReach from here →
1. 9-cis-retinol:NAD+ oxidoreductase
2. 9-cis-retinol + hexadecanoyl-CoA = 9-cis-retinyl hexadecanoate + CoA
Catalysed by HSD17B6, RDH16, ADH4, RBP3 and 6 more

Three steps

CHEBI:1146900Reach from here →
Catalysed by HSD17B6, RDH16, ADH4, RBP3 and 9 morecytosol
2-hydroxybutyric acidReach from here →
Catalysed by and 3 more

cytosol

all-trans-retinoic acidReach from here →

Catalysed by ALDH1A2, ALDH1A1, ALDH1A3cytosolOne of 3 routes

11-cis-retinalReach from here →

Catalysed by RBP1, RBP2cytosol

all-trans-retinolReach from here →

Catalysed by AKR1B15, AKR1B10, DHRS3, AKR1B1 and 7 morecytosol

1-O-acyl-sn-glycero-3-phosphocholine(1+)Reach from here →

Catalysed by HSD17B6, RDH16, ADH4, RBP3 and 5 morecytosol

9-cis-retinyl esterReach from here →

Catalysed by HSD17B6, RDH16, ADH4, RBP3 and 6 morecytosol

all-trans-retinoateReach from here →

Catalysed by ALDH1A2, ALDH1A1, ALDH1B1, ALDH1A3 and 1 morecytosolOne of 2 routes

13-cis-retinalReach from here →

No catalyst recordedcytosolOne of 2 routes

ALDH1A2

, ALDH1A1

, ALDH1A3

, SLC16A4

cytosol, extracellular space

One of 2 routes

AReach from here →

Catalysed by AKR1B15, AKR1B10, DHRS3, AKR1B1 and 8 morecytosol

all-trans-3,4-didehydroretinolReach from here →

Catalysed by AKR1B15, AKR1B10, DHRS3, AKR1B1 and 8 morecytosol

all-trans-4-hydroxyretinolReach from here →

Catalysed by AKR1B15, AKR1B10, DHRS3, AKR1B1 and 8 morecytosol

all-trans-4-hydroxyretinoateReach from here →

Catalysed by ALDH1A2, ALDH1A1, ALDH1A3, CYP26A1cytosolOne of 4 routes

acetoacetateReach from here →

Catalysed by ALDH1A2, ALDH1A1, ALDH1A3, SLC16A4 and 1 morecytosol, extracellular spaceOne of 2 routes

all-trans-retinyl tetradecanoateReach from here →

Catalysed by AKR1B15, AKR1B10, DHRS3, AKR1B1 and 8 morecytosol

all-trans-retinoyl-1-O-(beta-D-glucuronate)Reach from here →

Catalysed by ALDH1A2, ALDH1A1, ALDH1A3, UGT1A1 and 2 morecytosol, endoplasmic reticulumOne of 2 routes

all-trans-18-hydroxyretinoateReach from here →

Catalysed by ALDH1A2, ALDH1A1, ALDH1A3, CYP1A1 and 24 morecytosolOne of 3 routes

pyruvateReach from here →

Catalysed by ALDH1A2, ALDH1A1, ALDH1A3, SLC16A4 and 5 morecytosol, extracellular spaceOne of 2 routes

all-trans-3-hydroxyretinolReach from here →

Catalysed by AKR1B15, AKR1B10, DHRS3, AKR1B1 and 8 morecytosol

1,2-diacyl-sn-glycero-3-phosphocholine(1+)Reach from here →

Catalysed by HSD17B6, RDH16, ADH4, RBP3 and 9 morecytosol

11-cis-retinolReach from here →

Catalysed by RBP1, RBP2, HSD17B6, RDH16 and 5 morecytosolOne of 6 routes

sn-glycerol 3-phosphocholineReach from here →

Catalysed by HSD17B6, RDH16, ADH4, RBP3 and 15 morecytosol

(R)-3-hydroxybutyric acidReach from here →

Catalysed by ALDH1A2, ALDH1A1, ALDH1A3, SLC16A4 and 3 morecytosol, extracellular spaceOne of 2 routes

all-trans-retinyl hexadecanoateReach from here →

Catalysed by AKR1B15, AKR1B10, DHRS3, AKR1B1 and 12 morecytosolOne of 2 routes

a diacylglycerolReach from here →

Catalysed by AKR1B15, AKR1B10, DHRS3, AKR1B1 and 9 morecytosol

acetateReach from here →

Catalysed by ALDH1A2, ALDH1A1, ALDH1A3, SLC16A4 and 2 morecytosol, extracellular spaceOne of 2 routes

formic acidReach from here →

Catalysed by ALDH1A2, ALDH1A1, ALDH1A3, SLC16A4 and 1 morecytosol, extracellular spaceOne of 2 routes

propionic acidReach from here →

Catalysed by ALDH1A2, ALDH1A1, ALDH1A3, SLC16A4 and 2 morecytosol, extracellular spaceOne of 2 routes

butyric acidReach from here →

Catalysed by ALDH1A2, ALDH1A1, ALDH1A3, SLC16A4 and 1 morecytosol, extracellular spaceOne of 2 routes

fatty acidReach from here →

Catalysed by HSD17B6, RDH16, ADH4, RBP3 and 15 morecytosol

(S)-lactic acidReach from here →

Catalysed by ALDH1A2, ALDH1A1, ALDH1A3, SLC16A4 and 5 morecytosol, extracellular spaceOne of 2 routes

all-trans-4-oxoretinolReach from here →

Catalysed by AKR1B15, AKR1B10, DHRS3, AKR1B1 and 8 morecytosol

13-cis-retinolReach from here →

Catalysed by RDH5cytosolOne of 5 routes

all-trans-13,14-dihydroretinolReach from here →

Catalysed by AKR1B15, AKR1B10, DHRS3, AKR1B1 and 8 morecytosol

an all-trans-retinyl esterReach from here →

Catalysed by AKR1B15, AKR1B10, DHRS3, AKR1B1 and 8 morecytosolOne of 4 routes

all-trans-retinyl 9Z-octadecenoateReach from here →

Catalysed by AKR1B15, AKR1B10, DHRS3, AKR1B1 and 9 morecytosol

di-(9Z)-octadecenoylglycerolReach from here →

Catalysed by AKR1B15, AKR1B10, DHRS3, AKR1B1 and 9 morecytosol

2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →

Catalysed by AKR1B15, AKR1B10, DHRS3, AKR1B1 and 8 morecytosol