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N-formylanthranilic acid

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

110 compounds within 3 steps: 2 in 1, 11 in 2, 97 in 3

Does it reach a compound?

One step

formic acidReach from here →
1. N-Formylanthranilate amidohydrolase
Catalysed by AFMIDcytosol
anthranilic acidReach from here →
1. N-Formylanthranilate amidohydrolase
Catalysed by AFMIDcytosol

Two steps

2-hydroxybutyric acidReach from here →
1. N-Formylanthranilate amidohydrolase
2. transport of 2-hydroxybutyrate and formate (cytosol to extracellular)
Catalysed by AFMID, SLC16A4, SLC16A5, SLC16A7 and 1 morecytosol, extracellular spaceOne of 2 routes
acetoacetateReach from here →
1. N-Formylanthranilate amidohydrolase
2. transport of acetoacetate and formate (cytosol to extracellular)
Catalysed by AFMID, SLC16A4, SLC16A5cytosol, extracellular space

Three steps

(S)-3-hydroxybutanoateReach from here →
Catalysed by AFMID, SLC16A4, SLC16A5, ADHFE1cytosol, extracellular space
(S)-carnitineReach from here →

Page 1 of 3

One of 2 routes

pyruvateReach from here →

N-Formylanthranilate amidohydrolase
transport of formate and pyruvate (cytosol to extracellular)

Catalysed by AFMID, SLC16A4, SLC16A5, SLC16A7 and 2 morecytosol, extracellular spaceOne of 2 routes

all-trans-retinoic acidReach from here →

N-Formylanthranilate amidohydrolase
transport of formate and retinoate (cytosol to extracellular)

Catalysed by AFMID, SLC16A4, SLC16A5cytosol, extracellular spaceOne of 2 routes

10-formyltetrahydrofolic acidReach from here →

N-Formylanthranilate amidohydrolase
Formate:tetrahydrofolate ligase (ADP-forming)

Catalysed by AFMID, MTHFD1cytosolOne of 2 routes

(R)-3-hydroxybutyric acidReach from here →

N-Formylanthranilate amidohydrolase
transport of (R)-3-hydroxybutanoate and formate (cytosol to extracellular)

Catalysed by AFMID, SLC16A4, SLC16A5, SLC16A7 and 1 morecytosol, extracellular spaceOne of 2 routes

chlorine(.)Reach from here →

N-Formylanthranilate amidohydrolase
transport of chloride and formate (cytosol to extracellular)

Catalysed by AFMID, SLC26A4cytosol, extracellular spaceOne of 2 routes

acetateReach from here →

N-Formylanthranilate amidohydrolase
transport of acetate and formate (cytosol to extracellular)

Catalysed by AFMID, SLC16A4, SLC16A5, SLC16A1cytosol, extracellular spaceOne of 2 routes

propionic acidReach from here →

N-Formylanthranilate amidohydrolase
transport of formate and propanoate (cytosol to extracellular)

Catalysed by AFMID, SLC16A4, SLC16A5, SLC16A1cytosol, extracellular spaceOne of 2 routes

butyric acidReach from here →

N-Formylanthranilate amidohydrolase
transport of butyrate and formate (cytosol to extracellular)

Catalysed by AFMID, SLC16A4, SLC16A5cytosol, extracellular spaceOne of 2 routes

(S)-lactic acidReach from here →

N-Formylanthranilate amidohydrolase
transport of formate and L-lactate (cytosol to extracellular)

Catalysed by AFMID, SLC16A4, SLC16A5, SLC16A3 and 3 morecytosol, extracellular spaceOne of 2 routes

Catalysed by AFMID, SLC26A4, SLC6A14

cytosol, extracellular space

prostaglandin E3Reach from here →

N-Formylanthranilate amidohydrolase
transport of formate and L-lactate (cytosol to extracellular)
Transport of Prostaglandin E3, Lactate Antiport

Catalysed by AFMID, SLC16A4, SLC16A5, SLC16A3 and 3 morecytosol, extracellular spaceOne of 2 routes

prostaglandin A2Reach from here →

N-Formylanthranilate amidohydrolase
transport of formate and L-lactate (cytosol to extracellular)
Transport of Prostaglandin A2, Lactate Antiport

Catalysed by AFMID, SLC16A4, SLC16A5, SLC16A3 and 3 morecytosol, extracellular spaceOne of 2 routes

prostaglandin J2Reach from here →

N-Formylanthranilate amidohydrolase
transport of formate and L-lactate (cytosol to extracellular)
Transport of Prostaglandin J2, Lactate Antiport

Catalysed by AFMID, SLC16A4, SLC16A5, SLC16A3 and 3 morecytosol, extracellular spaceOne of 2 routes

15-oxoprostaglandin F2alphaReach from here →

N-Formylanthranilate amidohydrolase
transport of formate and L-lactate (cytosol to extracellular)
Transport of 15-Keto-Prostaglandin F2A, Lactate Antiport

Catalysed by AFMID, SLC16A4, SLC16A5, SLC16A3 and 3 morecytosol, extracellular spaceOne of 2 routes

all-trans-4-hydroxyretinoateReach from here →

N-Formylanthranilate amidohydrolase
transport of formate and retinoate (cytosol to extracellular)
cytochrome P450 (retinoate)

Catalysed by AFMID, SLC16A4, SLC16A5, CYP26A1cytosol, extracellular spaceOne of 3 routes

N-acetylcadaverineReach from here →

N-Formylanthranilate amidohydrolase
transport of acetate and formate (cytosol to extracellular)
N-acetylcadaverine + H2O = cadaverine + acetate

Catalysed by AFMID, SLC16A4, SLC16A5, SLC16A1 and 1 morecytosol, extracellular space

all-trans-retinoyl-1-O-(beta-D-glucuronate)Reach from here →

N-Formylanthranilate amidohydrolase
transport of formate and retinoate (cytosol to extracellular)
glucuronosyltransferase (retinoate)

Catalysed by AFMID, SLC16A4, SLC16A5, UGT1A1 and 2 morecytosol, extracellular space, endoplasmic reticulum

all-trans-18-hydroxyretinoateReach from here →

N-Formylanthranilate amidohydrolase
transport of formate and retinoate (cytosol to extracellular)
unspecific monooxygenase (retinoate)

Catalysed by AFMID, SLC16A4, SLC16A5, CYP1A1 and 24 morecytosol, extracellular spaceOne of 2 routes

a phenyl acetateReach from here →

N-Formylanthranilate amidohydrolase
transport of acetate and formate (cytosol to extracellular)
a phenyl acetate + H2O = a phenol + acetate + H(+)

Catalysed by AFMID, SLC16A4, SLC16A5, SLC16A1 and 3 morecytosol, extracellular space

CHEBI:15345Reach from here →

N-Formylanthranilate amidohydrolase
transport of acetoacetate and formate (cytosol to extracellular)
Acetoacetate:CoA ligase (AMP-forming)

Catalysed by AFMID, SLC16A4, SLC16A5, AACScytosol, extracellular spaceOne of 3 routes

acetoneReach from here →

N-Formylanthranilate amidohydrolase
transport of acetoacetate and formate (cytosol to extracellular)
Acetoacetate carboxy-lyase (acetone-forming)

Catalysed by AFMID, SLC16A4, SLC16A5cytosol, extracellular space, mitochondrial matrix

cholineReach from here →

N-Formylanthranilate amidohydrolase
transport of chloride and formate (cytosol to extracellular)
transport of chloride and choline (cytosol to extracellular)

Catalysed by AFMID, SLC26A4, SLC5A7cytosol, extracellular space

acetylpyruvateReach from here →

N-Formylanthranilate amidohydrolase
transport of formate and pyruvate (cytosol to extracellular)
acetylpyruvate + H2O = acetate + pyruvate + H(+)

Catalysed by AFMID, SLC16A4, SLC16A5, SLC16A7 and 3 morecytosol, extracellular spaceOne of 2 routes

propionyl-CoAReach from here →

N-Formylanthranilate amidohydrolase
transport of formate and propanoate (cytosol to extracellular)
Propanoate:CoA ligase (AMP-forming)

Catalysed by AFMID, SLC16A4, SLC16A5, SLC16A1 and 3 morecytosol, extracellular spaceOne of 3 routes

(S)-malateReach from here →

N-Formylanthranilate amidohydrolase
transport of formate and pyruvate (cytosol to extracellular)
(S)-malate + NAD(+) = pyruvate + CO2 + NADH

Catalysed by AFMID, SLC16A4, SLC16A5, SLC16A7 and 3 morecytosol, extracellular spaceOne of 2 routes

L-leucineReach from here →

N-Formylanthranilate amidohydrolase
transport of chloride and formate (cytosol to extracellular)
transport of chloride and leucine (cytosol to extracellular)

Catalysed by AFMID, SLC26A4, SLC6A14cytosol, extracellular spaceOne of 2 routes

CHEBI:15971Reach from here →

N-Formylanthranilate amidohydrolase
transport of chloride and formate (cytosol to extracellular)
transport of chloride and histidine (cytosol to extracellular)

Catalysed by AFMID, SLC26A4, SLC6A14cytosol, extracellular space

sulfateReach from here →

N-Formylanthranilate amidohydrolase
transport of chloride and formate (cytosol to extracellular)
transport of chloride and sulfate (cytosol to extracellular)

Catalysed by AFMID, SLC26A4, SLC26A6cytosol, extracellular space

2-methyl-3-oxopropanoic acidReach from here →

N-Formylanthranilate amidohydrolase
transport of formate and pyruvate (cytosol to extracellular)
(R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase

Catalysed by AFMID, SLC16A4, SLC16A5, SLC16A7 and 3 morecytosol, extracellular space, mitochondrial matrix

iodideReach from here →

N-Formylanthranilate amidohydrolase
transport of chloride and formate (cytosol to extracellular)
transport of chloride and iodide (cytosol to extracellular)

Catalysed by AFMID, SLC26A4cytosol, extracellular space

L-valineReach from here →

N-Formylanthranilate amidohydrolase
transport of chloride and formate (cytosol to extracellular)
transport of chloride and valine (cytosol to extracellular)

Catalysed by AFMID, SLC26A4, SLC6A14cytosol, extracellular spaceOne of 2 routes

oxaloacetateReach from here →

N-Formylanthranilate amidohydrolase
transport of formate and pyruvate (cytosol to extracellular)
Pyruvate:carbon-dioxide ligase (ADP-forming)

Catalysed by AFMID, SLC16A4, SLC16A5, SLC16A7 and 3 morecytosol, extracellular space, mitochondrial matrixOne of 3 routes

L-arginineReach from here →

N-Formylanthranilate amidohydrolase
transport of chloride and formate (cytosol to extracellular)
transport of arginine and chloride (cytosol to extracellular)

Catalysed by AFMID, SLC26A4, SLC6A14cytosol, extracellular spaceOne of 2 routes

N(2)-acetyl-L-ornithineReach from here →

N-Formylanthranilate amidohydrolase
transport of acetate and formate (cytosol to extracellular)
N2-Acetyl-L-ornithine amidohydrolase

Catalysed by AFMID, SLC16A4, SLC16A5, SLC16A1 and 1 morecytosol, extracellular space

(S)-lactateReach from here →

N-Formylanthranilate amidohydrolase
transport of formate and pyruvate (cytosol to extracellular)
(S)-lactate + NAD(+) = pyruvate + NADH + H(+)

Catalysed by AFMID, SLC16A4, SLC16A5, SLC16A7 and 7 morecytosol, extracellular space

2-oxobutanoateReach from here →

N-Formylanthranilate amidohydrolase
transport of 2-hydroxybutyrate and formate (cytosol to extracellular)
2-hydroxybutyrate:NAD+ oxidoreductase

Catalysed by AFMID, SLC16A4, SLC16A5, SLC16A7 and 5 morecytosol, extracellular spaceOne of 2 routes

2-oxoglutaramateReach from here →

N-Formylanthranilate amidohydrolase
transport of formate and pyruvate (cytosol to extracellular)
L-Glutamine:pyruvate aminotransferase

Catalysed by AFMID, SLC16A4, SLC16A5, SLC16A7 and 3 morecytosol, extracellular spaceOne of 2 routes

3-fumarylpyruvateReach from here →

N-Formylanthranilate amidohydrolase
transport of formate and pyruvate (cytosol to extracellular)
3-fumarylpyruvate + H2O = fumarate + pyruvate + H(+)

Catalysed by AFMID, SLC16A4, SLC16A5, SLC16A7 and 3 morecytosol, extracellular space

CHEBI:16857Reach from here →

N-Formylanthranilate amidohydrolase
transport of chloride and formate (cytosol to extracellular)
Transport of L-Threonine by Atb0 Transporter

Catalysed by AFMID, SLC26A4, SLC6A14cytosol, extracellular space

ferrocytochrome cReach from here →

N-Formylanthranilate amidohydrolase
transport of formate and L-lactate (cytosol to extracellular)
(S)-Lactate:ferricytochrome-c 2-oxidoreductase

Catalysed by AFMID, SLC16A4, SLC16A5, SLC16A3 and 4 morecytosol, extracellular space, mitochondrial matrix

oxalic acidReach from here →

N-Formylanthranilate amidohydrolase
transport of chloride and formate (cytosol to extracellular)
transport of chloride and oxalate (cytosol to extracellular)

Catalysed by AFMID, SLC26A4, SLC26A6cytosol, extracellular space

3-hydroxypyruvateReach from here →

N-Formylanthranilate amidohydrolase
transport of formate and pyruvate (cytosol to extracellular)
L-serine + pyruvate = 3-hydroxypyruvate + L-alanine

Catalysed by AFMID, SLC16A4, SLC16A5, SLC16A7 and 3 morecytosol, extracellular space

L-isoleucineReach from here →

N-Formylanthranilate amidohydrolase
transport of chloride and formate (cytosol to extracellular)
transport of chloride and isoleucine (cytosol to extracellular)

Catalysed by AFMID, SLC26A4, SLC6A14cytosol, extracellular spaceOne of 2 routes

CHEBI:17203Reach from here →

N-Formylanthranilate amidohydrolase
transport of chloride and formate (cytosol to extracellular)
Transport of L-Proline by the Apical Imino Amino Acid Transporters

Catalysed by AFMID, SLC26A4, CLTRN, SLC6A20cytosol, extracellular spaceOne of 2 routes

17alpha-hydroxyprogesteroneReach from here →

N-Formylanthranilate amidohydrolase
transport of acetate and formate (cytosol to extracellular)
cytochrome P450 (17alpha-hydroxyprogesterone)

Catalysed by AFMID, SLC16A4, SLC16A5, SLC16A1 and 1 morecytosol, extracellular space, endoplasmic reticulum