thiosulfate
362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API
308 compounds within 3 steps: 8 in 1, 55 in 2, 245 in 3
Two steps
- transport of malate and thiosulfate (cytosol to mitochondria)
- (S)-malate + ATP + CoA = (S)-malyl-CoA + ADP + phosphate
Catalysed by SLC25A10, SUCLG1, SUCLA2mitochondrial matrix, cytosol
- transport of fumarate and thiosulfate (cytosol to mitochondria)
- 2-(Nomega-L-arginino)succinate arginine-lyase (fumarate-forming)
Catalysed by SLC25A10, ASLmitochondrial matrix, cytosolOne of 2 routes
- transport of fumarate and thiosulfate (cytosol to mitochondria)
- N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming)
Catalysed by SLC25A10, ADSL, TNRC6Bmitochondrial matrix, cytosolOne of 2 routes
- 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (H2S2O3)
- 2-oxo-3-sulfanylpropanoate + [thioredoxin]-dithiol = [thioredoxin]-disulfide + hydrogen sulfide + pyruvate + H(+)
Catalysed by MPSTcytosol
- 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (H2S2O3)
- N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate
Catalysed by SGSHcytosol
- 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (H2S2O3)
- dehydroepiandrosterone 3-sulfate + H2O = 3beta-hydroxyandrost-5-en-17-one + sulfate + H(+)
Catalysed by STScytosol
- 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (H2S2O3)
- thiosulfate + 2 glutathione = glutathione disulfide + hydrogen sulfide + sulfite + 2 H(+)
Catalysed by TSTD1cytosolOne of 9 routes
- transport of fumarate and thiosulfate (cytosol to mitochondria)
- 1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole AMP-lyase
Catalysed by SLC25A10, ADSLmitochondrial matrix, cytosolOne of 2 routes
- 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (H2S2O3)
- estrone 3-sulfate + H2O = estrone + sulfate + H(+)
Catalysed by STScytosol
Catalysed by SLC4A1cytosol, extracellular spaceOne of 2 routes
- 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (H2S2O3)
- ubiquinone-10 + hydrogen sulfide + sulfite + 2 H(+) = ubiquinol-10 + thiosulfate
Catalysed by SQORcytosolOne of 3 routes
Three steps
- 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (H2S2O3)
- L-serine hydro-lyase (adding hydrogen sulfide, L-cysteine-forming)
- N-acetylglutamate synthase (N-acetyl-L-cysteine)
Catalysed by CBS,