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Proteins/UNIPROT:O60701
Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans. Required for the biosynthesis of chondroitin sulfate and heparan sulfate. Required for embryonic development via its role in the biosynthesis of glycosaminoglycans (By similarity). Required for proper brain and neuronal development..
Function from UniProtKB (O60701), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
539 statements
539 statements · 6 reference databases · Subject: UGDH · Sources: Bgee, Hetionet, Human Protein Atlas, Reactome, Rhea, WikiPathways · Rows fetched: 300
2 reactions
water+2NAD(+)+MAM03108c3proton+2NADH(2-)+UDP-alpha-D-glucuronate
Catalysed by UGDH
Reaction pageLeft to rightBalancedEC 1.1.1.22cytosol
Human-GEM MAR04122CC BY 4.0Reference data
3 names
Resolves to: UGDH
Catalysed by UGDH
Reaction pageDirection not assertedBalanced
Rhea RHEA:23596CC BY 4.0Reference data