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Proteins/UNIPROT:P14091
May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain..
Function from UniProtKB (P14091), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
32 statements
32 statements · 3 reference databases · Subject: CTSE · Sources: Hetionet, Reactome, WikiPathways
15 reactions
MAM01308l+608ATP+1216water608ADP+63L-alanine+27L-arginine+17L-asparagine+36L-aspartate+35L-cysteine+62L-glutamate(1-)+20L-glutamine+13glycine+619proton+16CHEBI:15971
1 name
Resolves to: CTSE
Catalysed by CTSA or CTSG or LGMN or CTSZ or CTSH or CTSC or CTSD or CTSL or CTSV or CTSK or CTSS or CTSB and 5 more alternatives
Reaction pageLeft to rightBalancedlysosome
Human-GEM MAR05259CC BY 4.0Reference data
MAM01343l+422ATP+844water422ADP+34L-alanine+16L-arginine+19L-asparagine+25L-aspartate+3L-cysteine+29L-glutamate(1-)+17L-glutamine+16glycine+434proton+9CHEBI:15971+20L-isoleucine+59L-leucine+26CHEBI:18019+14L-methionine+25L-phenylalanine+422phosphate(3-)+16CHEBI:17203+30L-seryl residue+29CHEBI:16857+3L-tryptophan+9CHEBI:17895+24L-valine
Catalysed by CTSA or CTSG or LGMN or CTSZ or CTSH or CTSC or CTSD or CTSL or CTSV or CTSK or CTSS or CTSB and 5 more alternatives
Reaction pageLeft to rightBalancedlysosome
Human-GEM MAR05261CC BY 4.0Reference data
MAM01345l+417ATP+834water417ADP+26L-alanine+7L-arginine+19L-asparagine+24L-aspartate+3L-cysteine+32L-glutamate(1-)+18L-glutamine+24glycine+432proton+13CHEBI:15971+20L-isoleucine+51L-leucine+34CHEBI:18019+10L-methionine+27L-phenylalanine+417phosphate(3-)+19CHEBI:17203+25L-seryl residue+30CHEBI:16857+3L-tryptophan+6CHEBI:17895+27L-valine
Catalysed by CTSA or CTSG or LGMN or CTSZ or CTSH or CTSC or CTSD or CTSL or CTSV or CTSK or CTSS or CTSB and 5 more alternatives
Reaction pageLeft to rightBalancedlysosome
Human-GEM MAR05263CC BY 4.0Reference data
MAM01351l+4560ATP+9120water4560ADP+275L-alanine+150L-arginine+247L-asparagine+233L-aspartate+25L-cysteine+298L-glutamate(1-)+230L-glutamine+207glycine+4584proton+115CHEBI:15971+285L-isoleucine+533L-leucine+357CHEBI:18019+79L-methionine+224L-phenylalanine+4560phosphate(3-)+171CHEBI:17203+392L-seryl residue+300CHEBI:16857+37L-tryptophan+151CHEBI:17895+252L-valine
Catalysed by CTSA or CTSG or LGMN or CTSZ or CTSH or CTSC or CTSD or CTSL or CTSV or CTSK or CTSS or CTSB and 5 more alternatives
Reaction pageLeft to rightBalancedlysosome
Human-GEM MAR05265CC BY 4.0Reference data
2673ATP+MAM01827l+5346water2673ADP+134L-alanine+134L-arginine+138L-asparagine+176L-aspartate+48L-cysteine+186L-glutamate(1-)+110L-glutamine+262glycine+2747proton+62CHEBI:15971+104L-isoleucine+166L-leucine+154CHEBI:18019+48L-methionine+98L-phenylalanine+2673phosphate(3-)+114CHEBI:17203+278L-seryl residue+182CHEBI:16857+60L-tryptophan+98CHEBI:17895+122L-valine
Catalysed by CTSA or CTSG or LGMN or CTSZ or CTSH or CTSC or CTSD or CTSL or CTSV or CTSK or CTSS or CTSB and 5 more alternatives
Reaction pageLeft to rightBalancedlysosome
Human-GEM MAR05272CC BY 4.0Reference data
405ATP+810water+MAM02044l405ADP+30L-alanine+9L-arginine+21L-asparagine+25L-aspartate+12L-cysteine+25L-glutamate(1-)+17L-glutamine+31glycine+411proton+13CHEBI:15971+18L-isoleucine+31L-leucine+35CHEBI:18019+5L-methionine+8L-phenylalanine+405phosphate(3-)+21CHEBI:17203+18L-seryl residue+22CHEBI:16857+8L-tryptophan+21CHEBI:17895+36L-valine
Catalysed by CTSA or CTSG or LGMN or CTSZ or CTSH or CTSC or CTSD or CTSL or CTSV or CTSK or CTSS or CTSB and 5 more alternatives
Reaction pageLeft to rightBalancedlysosome
Human-GEM MAR05274CC BY 4.0Reference data
809ATP+1618water+MAM02753l809ADP+37L-alanine+42L-arginine+40L-asparagine+36L-aspartate+48L-cysteine+56L-glutamate(1-)+31L-glutamine+62glycine+810proton+24CHEBI:15971+22L-isoleucine+48L-leucine+49CHEBI:18019+11L-methionine+21L-phenylalanine+809phosphate(3-)+69CHEBI:17203+56L-seryl residue+61CHEBI:16857+19L-tryptophan+30CHEBI:17895+48L-valine
Catalysed by CTSA or CTSG or LGMN or CTSZ or CTSH or CTSC or CTSD or CTSL or CTSV or CTSK or CTSS or CTSB and 5 more alternatives
Reaction pageLeft to rightBalancedlysosome
Human-GEM MAR05276CC BY 4.0Reference data
621ATP+1242water+MAM02802l621ADP+42L-alanine+44L-arginine+25L-asparagine+35L-aspartate+26L-cysteine+51L-glutamate(1-)+26L-glutamine+49glycine+634proton+13CHEBI:15971+22L-isoleucine+51L-leucine+29CHEBI:18019+9L-methionine+21L-phenylalanine+621phosphate(3-)+33CHEBI:17203+38L-seryl residue+36CHEBI:16857+14L-tryptophan+21CHEBI:17895+37L-valine
Catalysed by CTSA or CTSG or LGMN or CTSZ or CTSH or CTSC or CTSD or CTSL or CTSV or CTSK or CTSS or CTSB and 5 more alternatives
Reaction pageLeft to rightBalancedlysosome
Human-GEM MAR05278CC BY 4.0Reference data
MAM00186l+697ATP+1394water697ADP+61L-alanine+27L-arginine+34L-asparagine+45L-aspartate+40L-cysteine+42L-glutamate(1-)+17L-glutamine+52glycine+699proton+19CHEBI:15971+15L-isoleucine+65L-leucine+58CHEBI:18019+10L-methionine+28L-phenylalanine+697phosphate(3-)+32CHEBI:17203+41L-seryl residue+30CHEBI:16857+8L-tryptophan+26CHEBI:17895+48L-valine
Catalysed by CTSA or CTSG or LGMN or CTSZ or CTSH or CTSC or CTSD or CTSL or CTSV or CTSK or CTSS or CTSB and 5 more alternatives
Reaction pageLeft to rightBalancedlysosome
Human-GEM MAR05280CC BY 4.0Reference data
MAM01359l+316ATP+632water316ADP+39L-alanine+34L-arginine+L-asparagine+11L-aspartate+2L-cysteine+40L-glutamate(1-)+32L-glutamine+18glycine+320proton+2CHEBI:15971+2L-isoleucine+41L-leucine+13CHEBI:18019+8L-methionine+4L-phenylalanine+316phosphate(3-)+8CHEBI:17203+14L-seryl residue+12CHEBI:16857+8L-tryptophan+4CHEBI:17895+24L-valine
Catalysed by CTSA or CTSG or LGMN or CTSZ or CTSH or CTSC or CTSD or CTSL or CTSV or CTSK or CTSS or CTSB and 5 more alternatives
Reaction pageLeft to rightBalancedlysosome
Human-GEM MAR05282CC BY 4.0Reference data
MAM01350l+266ATP+532water266ADP+23L-alanine+17L-arginine+5L-asparagine+16L-aspartate+30L-glutamate(1-)+19L-glutamine+11glycine+273proton+6CHEBI:15971+41L-leucine+22CHEBI:18019+4L-methionine+8L-phenylalanine+266phosphate(3-)+10CHEBI:17203+16L-seryl residue+12CHEBI:16857+5L-tryptophan+7CHEBI:17895+15L-valine
Catalysed by CTSA or CTSG or LGMN or CTSZ or CTSH or CTSC or CTSD or CTSL or CTSV or CTSK or CTSS or CTSB and 5 more alternatives
Reaction pageLeft to rightBalancedlysosome
Human-GEM MAR05284CC BY 4.0Reference data
284ATP+568water+MAM02935l284ADP+21L-alanine+20L-arginine+11L-asparagine+10L-aspartate+5L-cysteine+22L-glutamate(1-)+17L-glutamine+21glycine+277proton+6CHEBI:15971+10L-isoleucine+31L-leucine+19CHEBI:18019+12L-methionine+6L-phenylalanine+284phosphate(3-)+12CHEBI:17203+20L-seryl residue+12CHEBI:16857+5L-tryptophan+4CHEBI:17895+21L-valine
Catalysed by CTSA or CTSG or LGMN or CTSZ or CTSH or CTSC or CTSD or CTSL or CTSV or CTSK or CTSS or CTSB and 5 more alternatives
Reaction pageLeft to rightBalancedlysosome
Human-GEM MAR05285CC BY 4.0Reference data