Proteins/UNIPROT:Q9Y4Z0

LSM4

ProteinUNIPROT:Q9Y4Z0

Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA..

Function from UniProtKB (Q9Y4Z0), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

73 statements

73 statements · 3 reference databases · Subject: LSM4 · Sources: Hetionet, Reactome, WikiPathways

Order

AP1S1 covaries with LSM4ProteinHetionet hetionet:covaries:1174-25804Inferred only
SYNPO covaries with LSM4ProteinHetionet hetionet:covaries:11346-25804Inferred only
CALCOCO2 interacts with LSM4ProteinHetionet hetionet:interacts:10241-25804Inferred only
LSM4 interacts with LSM1ProteinHetionet hetionet:interacts:25804-27257Inferred only
LSM4 interacts with LSM7ProteinHetionet hetionet:interacts:25804-51690Inferred only
LSM4 interacts with MEPCEProteinHetionet hetionet:interacts:25804-56257Inferred only
LSM4 interacts with NAA38ProteinHetionet hetionet:interacts:25804-84316Inferred only
NMI interacts with LSM4ProteinHetionet hetionet:interacts:25804-9111Inferred only
LSM4 interacts with RHOXF2ProteinHetionet hetionet:interacts:25804-84528Inferred only
SLC22A2 interacts with LSM4ProteinHetionet hetionet:interacts:25804-6582Inferred only
LSM4 interacts with SMIM14ProteinHetionet hetionet:interacts:201895-25804Inferred only
SMN1; SMN2 interacts with LSM4ProteinHetionet hetionet:interacts:25804-6607Inferred only

Show the remaining 61

SMN1; SMN2 interacts with LSM4ProteinHetionet hetionet:interacts:25804-6606Inferred only
LSM4 interacts with SMU1ProteinHetionet hetionet:interacts:25804-55234Inferred only
SNRPE interacts with LSM4ProteinHetionet hetionet:interacts:25804-6635Inferred only
LSM4 interacts with TOE1ProteinHetionet hetionet:interacts:114034-25804Inferred only
TOP1 interacts with LSM4ProteinHetionet hetionet:interacts:25804-7150Inferred only
UBC interacts with LSM4ProteinHetionet hetionet:interacts:25804-7316Inferred only
LSM4 interacts with XRN1ProteinHetionet hetionet:interacts:25804-54464Inferred only
LSM4 participates in Ciliary landscapePathwayWikiPathways WP4352Inferred only
LSM4 participates in Deadenylation-dependent mRNA decayPathwayReactome R-HSA-429914Inferred only
LSM4 participates in Metabolism of RNAPathwayReactome R-HSA-8953854Inferred only
LSM4 participates in mRNA decay by 5' to 3' exoribonucleasePathwayReactome R-HSA-430039Inferred only
LSM4 participates in mRNA SplicingPathwayReactome R-HSA-72172Inferred only
LSM4 participates in mRNA Splicing - Major PathwayPathwayReactome R-HSA-72163Inferred only
LSM4 participates in Processing of Capped Intron-Containing Pre-mRNAPathwayReactome R-HSA-72203Inferred only
AKR1C3 decreases the expression of LSM4ProteinHetionet hetionet:regulates:8644-25804Inferred only
ARHGAP35 decreases the expression of LSM4ProteinHetionet hetionet:regulates:2909-25804Inferred only
BAD increases the expression of LSM4ProteinHetionet hetionet:regulates:572-25804Inferred only
BPHL decreases the expression of LSM4ProteinHetionet hetionet:regulates:670-25804Inferred only
CARD9 decreases the expression of LSM4ProteinHetionet hetionet:regulates:64170-25804Inferred only
COPZ1 decreases the expression of LSM4ProteinHetionet hetionet:regulates:22818-25804Inferred only
CTNNAL1 decreases the expression of LSM4ProteinHetionet hetionet:regulates:8727-25804Inferred only
DDR1 decreases the expression of LSM4ProteinHetionet hetionet:regulates:780-25804Inferred only
DDX49 decreases the expression of LSM4ProteinHetionet hetionet:regulates:54555-25804Inferred only
DTNA decreases the expression of LSM4ProteinHetionet hetionet:regulates:1837-25804Inferred only
EBF1 decreases the expression of LSM4ProteinHetionet hetionet:regulates:1879-25804Inferred only
ERG decreases the expression of LSM4ProteinHetionet hetionet:regulates:2078-25804Inferred only
EXOSC4 decreases the expression of LSM4ProteinHetionet hetionet:regulates:54512-25804Inferred only
HERPUD1 decreases the expression of LSM4ProteinHetionet hetionet:regulates:9709-25804Inferred only
HS2ST1 decreases the expression of LSM4ProteinHetionet hetionet:regulates:9653-25804Inferred only
IFNB1 decreases the expression of LSM4ProteinHetionet hetionet:regulates:3456-25804Inferred only
LTBR decreases the expression of LSM4ProteinHetionet hetionet:regulates:4055-25804Inferred only
MAP3K8 decreases the expression of LSM4ProteinHetionet hetionet:regulates:1326-25804Inferred only
NIT1 decreases the expression of LSM4ProteinHetionet hetionet:regulates:4817-25804Inferred only
NKX2-3 decreases the expression of LSM4ProteinHetionet hetionet:regulates:159296-25804Inferred only
NUMA1 decreases the expression of LSM4ProteinHetionet hetionet:regulates:4926-25804Inferred only
PDS5A decreases the expression of LSM4ProteinHetionet hetionet:regulates:23244-25804Inferred only
PIAS2 decreases the expression of LSM4ProteinHetionet hetionet:regulates:9063-25804Inferred only
PRAF2 decreases the expression of LSM4ProteinHetionet hetionet:regulates:11230-25804Inferred only
PSMA1 decreases the expression of LSM4ProteinHetionet hetionet:regulates:5682-25804Inferred only
PSMB2 decreases the expression of LSM4ProteinHetionet hetionet:regulates:5690-25804Inferred only
PSMD3 decreases the expression of LSM4ProteinHetionet hetionet:regulates:5709-25804Inferred only
PTK2 decreases the expression of LSM4ProteinHetionet hetionet:regulates:5747-25804Inferred only
PTP4A1 decreases the expression of LSM4ProteinHetionet hetionet:regulates:7803-25804Inferred only
QRSL1 decreases the expression of LSM4ProteinHetionet hetionet:regulates:55278-25804Inferred only
RBM34 decreases the expression of LSM4ProteinHetionet hetionet:regulates:23029-25804Inferred only
RPS3 decreases the expression of LSM4ProteinHetionet hetionet:regulates:6188-25804Inferred only
RPS6KA3 increases the expression of LSM4ProteinHetionet hetionet:regulates:6197-25804Inferred only
RXRG decreases the expression of LSM4ProteinHetionet hetionet:regulates:6258-25804Inferred only
SLC16A1 decreases the expression of LSM4ProteinHetionet hetionet:regulates:6566-25804Inferred only
SLC35A1 decreases the expression of LSM4ProteinHetionet hetionet:regulates:10559-25804Inferred only
SMAD2 decreases the expression of LSM4ProteinHetionet hetionet:regulates:4087-25804Inferred only
SMAD7 decreases the expression of LSM4ProteinHetionet hetionet:regulates:4092-25804Inferred only
SPR decreases the expression of LSM4ProteinHetionet hetionet:regulates:6697-25804Inferred only
SRC decreases the expression of LSM4ProteinHetionet hetionet:regulates:6714-25804Inferred only
STAT1 decreases the expression of LSM4ProteinHetionet hetionet:regulates:6772-25804Inferred only
TNFAIP1 decreases the expression of LSM4ProteinHetionet hetionet:regulates:7126-25804Inferred only
TP53BP1 increases the expression of LSM4ProteinHetionet hetionet:regulates:7158-25804Inferred only
TUBB2A decreases the expression of LSM4ProteinHetionet hetionet:regulates:7280-25804Inferred only
TUBB3 decreases the expression of LSM4ProteinHetionet hetionet:regulates:10381-25804Inferred only
UBC decreases the expression of LSM4ProteinHetionet hetionet:regulates:7316-25804Inferred only
UGDH decreases the expression of LSM4ProteinHetionet hetionet:regulates:7358-25804Inferred only

Other names

2 names

Resolves to: LSM4

Also called: Glycine-rich proteinGRP

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