Loading the page.
Proteins/UNIPROT:Q92794
Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2. Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML. May play a role in leukemogenic gene transcription..
Function from UniProtKB (Q92794), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
396 statements
396 statements · 7 reference databases · Subject: KAT6A · Sources: Bgee, gene ontology, Hetionet, Human Protein Atlas, Human-GEM, Reactome, WikiPathways · Rows fetched: 300
2 reactions
9 names
Resolves to: KAT6A
Human-GEM MAR09495CC BY 4.0Reference data
L-lysyl-[protein]+acetyl-CoAN(6)-acetyl-L-lysyl-[protein]+coenzyme A(4-)+hydron
Catalysed by HAT1 or CLOCK or TAF1 or BLOC1S1 or GTF2B or EP300 or NCOA1 or ESCO2 or ESCO1 or KAT6B or CREBBP or KAT6A and 12 more alternatives
Reaction pageReversibleBalance undeterminable
Rhea RHEA:45948CC BY 4.0Reference data