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Proteins/UNIPROT:P62805
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Function from UniProtKB (P62805), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
4 rows
2,412 statements
2,412 statements · 4 reference databases · Subject: H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 · Sources: gene ontology, Hetionet, Reactome, WikiPathways · Rows fetched: 300
44 names
Resolves to: H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16