Proteins/UNIPROT:P29275

ADORA2B

ProteinUNIPROT:P29275Adenosine receptor A2b. Part of the receptor set caffeine antagonises non-selectively.

Open in the graph

Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

Function from UniProtKB (P29275), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

61 statements

61 statements · 3 reference databases · Subject: ADORA2B · Sources: Hetionet, Reactome, WikiPathways

Order

ADORA2B covaries with WNT4ProteinHetionet hetionet:covaries:136-54361Inferred only
ADA interacts with ADORA2BProteinHetionet hetionet:interacts:100-136Inferred only
ADORA2B interacts with DCCProteinHetionet hetionet:interacts:136-1630Inferred only
ADORA2B interacts with EZRProteinHetionet hetionet:interacts:136-7430Inferred only
ADORA2B interacts with NHERF2ProteinHetionet hetionet:interacts:136-9351Inferred only
ADORA2B interacts with NTN1ProteinHetionet hetionet:interacts:136-9423Inferred only
ADORA2B interacts with TPD52L2ProteinHetionet hetionet:interacts:136-7165Inferred only
ADORA2B interacts with ZNF267ProteinHetionet hetionet:interacts:10308-136Inferred only
ADORA2B participates in Adenosine P1 receptorsPathwayReactome R-HSA-417973Inferred only
ADORA2B participates in ADORA2B mediated anti-inflammatory cytokines productionPathwayReactome R-HSA-9660821Inferred only
ADORA2B participates in Anti-inflammatory response favouring Leishmania parasite infectionPathwayReactome R-HSA-9662851Inferred only
ADORA2B participates in Caffeine in blood vesselsPathwayWikiPathways WP5601Inferred only

Show the remaining 49

ADORA2B participates in Class A/1 (Rhodopsin-like receptors)PathwayReactome R-HSA-373076Inferred only
ADORA2B participates in DiseasePathwayReactome R-HSA-1643685Inferred only
ADORA2B participates in G alpha (s) signalling eventsPathwayReactome R-HSA-418555Inferred only
ADORA2B participates in GPCR downstream signallingPathwayReactome R-HSA-388396Inferred only
ADORA2B participates in GPCR ligand bindingPathwayReactome R-HSA-500792Inferred only
ADORA2B participates in GPCRs class A rhodopsin likePathwayWikiPathways WP455Inferred only
ADORA2B participates in Infectious diseasePathwayReactome R-HSA-5663205Inferred only
ADORA2B participates in Leishmania infectionPathwayReactome R-HSA-9658195Inferred only
ADORA2B participates in Leishmania parasite growth and survivalPathwayReactome R-HSA-9664433Inferred only
ADORA2B participates in Metabolism of proteinsPathwayReactome R-HSA-392499Inferred only
ADORA2B participates in Nucleotide GPCRsPathwayWikiPathways WP80Inferred only
ADORA2B participates in Nucleotide-like (purinergic) receptorsPathwayReactome R-HSA-418038Inferred only
ADORA2B participates in p53 transcriptional gene networkPathwayWikiPathways WP4963Inferred only
ADORA2B participates in Parasitic Infection PathwaysPathwayReactome R-HSA-9824443Inferred only
ADORA2B participates in Purinergic signalingPathwayWikiPathways WP4900Inferred only
ADORA2B participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
ADORA2B participates in Signaling by GPCRPathwayReactome R-HSA-372790Inferred only
ADORA2B participates in Surfactant metabolismPathwayReactome R-HSA-5683826Inferred only
ADORA2B decreases the expression of ANO10ProteinHetionet hetionet:regulates:136-55129Inferred only
ADORA2B decreases the expression of BIDProteinHetionet hetionet:regulates:136-637Inferred only
ADORA2B decreases the expression of CATProteinHetionet hetionet:regulates:136-847Inferred only
CD58 decreases the expression of ADORA2BProteinHetionet hetionet:regulates:965-136Inferred only
ADORA2B decreases the expression of CHMP4AProteinHetionet hetionet:regulates:136-29082Inferred only
ADORA2B increases the expression of CRYZProteinHetionet hetionet:regulates:136-1429Inferred only
ADORA2B increases the expression of CXCL2ProteinHetionet hetionet:regulates:136-2920Inferred only
ADORA2B decreases the expression of FIS1ProteinHetionet hetionet:regulates:136-51024Inferred only
HMGCR decreases the expression of ADORA2BProteinHetionet hetionet:regulates:3156-136Inferred only
HSF1 decreases the expression of ADORA2BProteinHetionet hetionet:regulates:3297-136Inferred only
ADORA2B decreases the expression of LPGAT1ProteinHetionet hetionet:regulates:136-9926Inferred only
ADORA2B decreases the expression of LRP10ProteinHetionet hetionet:regulates:136-26020Inferred only
ADORA2B increases the expression of MMP1ProteinHetionet hetionet:regulates:136-4312Inferred only
ADORA2B decreases the expression of MTHFD2ProteinHetionet hetionet:regulates:136-10797Inferred only
ADORA2B increases the expression of PLAC8ProteinHetionet hetionet:regulates:136-51316Inferred only
ADORA2B decreases the expression of PLS1ProteinHetionet hetionet:regulates:136-5357Inferred only
ADORA2B decreases the expression of PPP2R5AProteinHetionet hetionet:regulates:136-5525Inferred only
PRKDC decreases the expression of ADORA2BProteinHetionet hetionet:regulates:5591-136Inferred only
ADORA2B decreases the expression of PSMB8ProteinHetionet hetionet:regulates:136-5696Inferred only
ADORA2B increases the expression of RGS2ProteinHetionet hetionet:regulates:136-5997Inferred only
ADORA2B decreases the expression of RPS4Y1ProteinHetionet hetionet:regulates:136-6192Inferred only
ADORA2B decreases the expression of SACM1LProteinHetionet hetionet:regulates:136-22908Inferred only
ADORA2B decreases the expression of SPON2ProteinHetionet hetionet:regulates:136-10417Inferred only
ADORA2B decreases the expression of SPRED2ProteinHetionet hetionet:regulates:136-200734Inferred only
ADORA2B decreases the expression of SUZ12ProteinHetionet hetionet:regulates:136-23512Inferred only
ADORA2B decreases the expression of TUBA1AProteinHetionet hetionet:regulates:136-7846Inferred only
ADORA2B decreases the expression of TUBB6ProteinHetionet hetionet:regulates:136-84617Inferred only
ADORA2B decreases the expression of TXNRD1ProteinHetionet hetionet:regulates:136-7296Inferred only
ADORA2B decreases the expression of UBE3CProteinHetionet hetionet:regulates:136-9690Inferred only
ADORA2B decreases the expression of UGDHProteinHetionet hetionet:regulates:136-7358Inferred only
ADORA2B decreases the expression of WASHC4ProteinHetionet hetionet:regulates:136-23325Inferred only

Other names

1 name

Resolves to: ADORA2B

Also called: Adenosine receptor A2b

← Every protein Find it in the graph →