Loading the page.
Proteins/UNIPROT:O75496
Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle. Inhibits histone acetyltransferase activity of KAT7/HBO1 in a CDT1-dependent manner, inhibiting histone H4 acetylation and DNA replication licensing. Inhibits the transcriptional activity of a subset of Hox proteins, enrolling them in cell proliferative control..
Function from UniProtKB (O75496), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
255 statements
255 statements · 4 reference databases · Subject: GMNN · Sources: gene ontology, Hetionet, Reactome, WikiPathways
1 name
Resolves to: GMNN