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Proteins/UNIPROT:Q14241
SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex)..
As part of a multisubunit complex composed of elongin BC complex (ELOB and ELOC), elongin A/ELOA, RBX1 and CUL5; polyubiquitinates monoubiquitinated POLR2A..
Function from UniProtKB (Q14241), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
59 statements
59 statements · 4 reference databases · Subject: ELOA · Sources: gene ontology, Hetionet, Reactome, WikiPathways
5 names
Resolves to: ELOA