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Proteins/UNIPROT:Q9P2T1
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Plays a role in modulating cellular differentiation..
Function from UniProtKB (Q9P2T1), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
149 statements
149 statements · 4 reference databases · Subject: GMPR2 · Sources: Bgee, Hetionet, Reactome, Rhea
2 reactions
GMP+proton+NADPH(4-)CHEBI:17202+NADP(3-)+ammonium
Reaction pageLeft to rightBalancedEC 1.7.1.7cytosol
Human-GEM MAR04419CC BY 4.0Reference data
3 names
Resolves to: GMPR2
Reaction pageDirection not assertedBalanced
Rhea RHEA:17185CC BY 4.0Reference data