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Proteins/UNIPROT:Q14353
Converts guanidinoacetate to creatine, using S-adenosylmethionine as the methyl donor. Important in nervous system development..
Function from UniProtKB (Q14353), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 1 · substrate of
1 compound
1 compound.
0 reported routes1 assembled route
1 row
138 statements
138 statements · 6 reference databases · Subject: GAMT · Sources: Bgee, Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
2 reactions
creatine+proton+CHEBI:16680guanidinoacetate+S-adenosyl-L-methionine
Catalysed by GAMT
Reaction pageReversibleBalancedEC 2.1.1.2cytosol
Human-GEM MAR04583CC BY 4.0Reference data
guanidinoacetate+S-adenosyl-L-methioninecreatine+S-adenosyl-L-homocysteine+hydron
Catalysed by GAMT
1 name
Resolves to: GAMT
Reaction pageDirection not assertedBalanced
Rhea RHEA:10656CC BY 4.0Reference data