Compound
NAD(+)
A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (nadh). (Dorland, 27th ed)
Structure
The oxidised form of nicotinamide adenine dinucleotide found in all living cells. In metabolism, NAD+ is involved in redox reactions, carrying electrons from one reaction to another.
Loading the model…
- Class
- Organic compound, cation
- Formula
- C21H28N7O14P2
- Mass
- 664.438 g/mol
- Charge
- +1
- InChIKey
- BAWFJGJZGIEFAR-NNYOXOHSSA-O
- SMILES
- NC(=O)c1ccc[n+]([C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@H](O)[C@@H]3O)[C@@H](O)[C@H]2O)c1
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
Reactions
625 reactions
A common cofactor or currency species. Appears in 625 reactions — see the full list.
On the label
Labelled products
19 products
Source: NIH DSLD · Ingredient: NAD(+) · 19 products · Declared amount per serving: 5–250 mg (15 products)
19 labels state an amount0 do not
- Alive By NatureLSG NAD+250 mgper 2 mLDSLD:230822
- Alive By ScienceNAD+ Micromist25 mgper 2 Spray(s)DSLD:266191
- Axis Pharmaceutics Inc.Vitazyme Tablets5 mgper 1 Tablet(s)DSLD:263329
- CenturionBump DHA25 mcgper 1 Softgel Capsule(s)DSLD:263410
- CenturionBumP DHA25 mcgper 1 Softgel(s)DSLD:335953
- Centurion HealthBump MSVitamin B350 mcgper 2 Capsule(s)DSLD:335956
- Core Med ScienceLiposomal NAD+100 mgper 4 Milliliter(s)DSLD:291896
- Country LifeCoenzyme B-Complex AdvancedNicotinamide Adenine Dinucleotide (Alt. Name: NADH) Note: reduced500 mcgper 1 Capsule(s)DSLD:277183
- DaVinci Laboratories Of VermontFibro-DMG5 mgper 1 Tablet(s)DSLD:22531
- Ecological FormulasNADH 5 mg5 mgper 1 Tablet(s)DSLD:299781
- NOWLiquid CoQ105 mgper 1 tspDSLD:14626
- NOWLiquid CoQ105 mgper 1 tspDSLD:55751
Show the remaining 7
- NOWLiquid CoQ10 Natural Orange Flavor5 mgper 5 mLDSLD:314422
- Premier Research LabsPremier NADH10 mgper 1 Capsule(s)DSLD:297551
- Protocol for Life BalanceLiquid CoQ105 mgper 0.5 tspDSLD:11424
- Seeking HealthNADH + CoQ10Nicotinamide Adenine Dinucleotide Complex · PANMOL NADHmicro (Form: reduced Nicotinamide Adenine Dinucleotide Complex)25 mgper 1 Lozenge(s)DSLD:174540
- SuperSmartNADH 5 mg5 mgper 1 Capsule(s)DSLD:250494
- SuperSmartNADH 5 mg5 mgper 1 Capsule(s)DSLD:285320
- Vera's FormulationsActivated B35 mgper 1 Capsule(s)DSLD:256591
Label record: NIH Office of Dietary Supplements · CC0
Papers screened
234 papers
- Compound
- NAD(+)
- Screened
- 234
- Admitted
- 0
- Discarded
- 39
- Not read
- 195
- Showing
- 200 of 234
Discarded: another reason, stated per paper23 papers
- NCT00098774design×1 — allocation NA -- not randomised2026-09-21
- NCT00511238design×1 — allocation NON_RANDOMIZED -- not randomised2026-09-21
- NCT00511329design×1 — allocation NA -- not randomised2026-09-21
- NCT00530816design×1 — allocation NA -- not randomised2026-09-21
- NCT00742157design×1 — allocation NA -- not randomised2026-09-21
and 18 more.
Discarded: the wrong intervention16 papers
- NCT00481871intervention×1 — no declared intervention names NAD(+)2026-09-21
and 15 more.
Not read yet195 papers
- PMID:103972412026-09-29
- PMID:110235382026-09-29
- PMID:112223892026-09-29
- PMID:113191692026-09-29
- PMID:115514082026-09-29
- PMID:116791762026-09-29
- PMID:120181062026-09-29
- PMID:124262142026-09-29
- PMID:127710352026-09-29
- PMID:145067372026-09-29
- PMID:146757322026-09-29
- PMID:14765772026-09-29
and 183 more.
Other names
9 names
Resolves to: NAD(+)
- Also called
- beta-NADDiphosphopyridine nucleotideDPNNADNAD+NadideNicotinamide adenine dinucleotideβ-NAD
- Systematic name
- adenosine 5'-{3-[1-(3-carbamoylpyridinio)-1,4-anhydro-D-ribitol-5-yl] dihydrogen diphosphate}