N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

588 compounds within 3 steps: 4 in 1, 130 in 2, 454 in 3

Two steps

L-citrullineReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. transport of citrulline and glycine (cytosol to extracellular)
Catalysed by FAAH, PM20D1, SLC7A9, SLC3A1 and 1 moreextracellular space, cytosol
L-valineReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. transport of glycine and valine (cytosol to extracellular)
Catalysed by FAAH, PM20D1, SLC7A5extracellular space, cytosolOne of 4 routes
L-arginineReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. transport of arginine and glycine (cytosol to extracellular)
Catalysed by FAAH, PM20D1, SLC7A6extracellular space, cytosolOne of 2 routes
CHEBI:16523Reach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. transport of D-serine and glycine (cytosol to extracellular)
Catalysed by FAAH, PM20D1, SLC3A2, SLC7A10extracellular space, cytosolOne of 2 routes
protein polypeptide chainReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. PROTEIN_BS
Catalysed by FAAH, PM20D1cytosol
CHEBI:16856Reach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. transport of arachidonate and GSH (cytosol to extracellular)
Catalysed by FAAH, PM20D1extracellular space, cytosolOne of 3 routes
CHEBI:16857Reach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. transport of glycine and threonine (cytosol to extracellular)
Catalysed by FAAH, PM20D1, SLC3A2, SLC7A5 and 1 moreextracellular space, cytosolOne of 4 routes
glyoxylic acidReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. glycine:oxygen oxidoreductase (deaminating)
Catalysed by FAAH, PM20D1, DAOperoxisome
L-isoleucineReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. transport of glycine and isoleucine (cytosol to extracellular)
Catalysed by FAAH, PM20D1, SLC7A5extracellular space, cytosolOne of 4 routes
CHEBI:17203Reach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. transport of glycine and proline (cytosol to extracellular)
Catalysed by FAAH, PM20D1, SLC7A5, SLC7A6extracellular space, cytosolOne of 2 routes
5-aminolevulinic acidReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. succinyl-CoA:glycine C-succinyltransferase (decarboxylating)
Catalysed by FAAH, PM20D1, ALAS1, ALAS2 and 1 moremitochondrial matrix
L-cysteineReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. transport of cysteine and glycine (cytosol to extracellular)
Catalysed by FAAH, PM20D1, SLC3A2, SLC7A5 and 1 moreextracellular space, cytosolOne of 4 routes
CHEBI:17895Reach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. transport of glycine and tyrosine (cytosol to extracellular)
Catalysed by FAAH, PM20D1, SLC7A5extracellular space, cytosolOne of 4 routes
CHEBI:18019Reach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. transport of glycine and lysine (cytosol to extracellular)
Catalysed by FAAH, PM20D1, SLC7A6extracellular space, cytosolOne of 2 routes
L-glutamineReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. transport of glutamine and glycine (cytosol to extracellular)
Catalysed by FAAH, PM20D1, SLC7A5extracellular space, cytosolOne of 4 routes
N(1)-(5-phospho-D-ribosyl)glycinamideReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. 5-Phospho-D-ribosylamine:glycine ligase (ADP-forming)
Catalysed by FAAH, PM20D1, GARTcytosol
ophthalmateReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. gamma-L-glutamyl-(2S)-2-aminobutanoate + glycine + ATP = ophthalmate + ADP + phosphate + H(+)
Catalysed by FAAH, PM20D1, GSS
N(omega),N('omega)-dimethyl-L-arginineReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. N(omega),N('omega)-dimethyl-L-arginine + glyoxylate = 5-(3,3'-dimethylguanidino)-2-oxopentanoate + glycine
Catalysed by FAAH, PM20D1, AGXT2
5,6,7,8-tetrahydrofolic acidReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. 5,10-Methylenetetrahydrofolate:glycine hydroxymethyltransferase
Catalysed by FAAH, PM20D1, SHMT1cytosolOne of 2 routes
O-[(5Z),(8Z),(11Z),(14Z)-eicosatetraenoyl]-beta-D-glucuronateReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + UDP-alpha-D-glucuronate = O-[(5Z),(8Z),(11Z),(14Z)-eicosatetraenoyl]-beta-D-glucuronate + UDP
Catalysed by FAAH, PM20D1, UGT1A9, UGT2B7 and 4 more
CHEBI:240943Reach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. glycine N-acyltransferase (2-methylbutyryl-CoA)
Catalysed by FAAH, PM20D1, GLYAT, GLYATL2 and 1 moremitochondrial matrix
N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamineReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. fatty acylamide amidohydrolase
Catalysed by FAAH, PM20D1cytosol
phenylacetylglycineReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. phenylacetyl-CoA:glycine N-phenylacetyltransferase
Catalysed by FAAH, PM20D1, GLYATcytosolOne of 3 routes
CHEBI:28666Reach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. LTD4 hydrolysis
Catalysed by FAAH, PM20D1cytosol
Gly-tRNA(Gly)Reach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. glycine:tRNA(Gly) ligase (AMP-forming)
Catalysed by FAAH, PM20D1, GARS1cytosol
chlorine(.)Reach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. transport of chloride and glycine (cytosol to extracellular)
Catalysed by FAAH, PM20D1, SLC6A9, SLC6A14extracellular space, cytosolOne of 3 routes
glycocholateReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. bile acid-CoA: amino acid N-acyltransferase
Catalysed by FAAH, PM20D1, BAATperoxisomeOne of 3 routes
fatty acidReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. (10Z)-heptadecenoic acid formation
Catalysed by FAAH, PM20D1cytosolOne of 4 routes
5-aminolevulinateReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. succinyl-CoA + glycine + H(+) = 5-aminolevulinate + CO2 + CoA
Catalysed by FAAH, PM20D1, ALAS1, ALAS2
glycochenodeoxycholateReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. chenodeoxycholoyl-CoA + glycine = glycochenodeoxycholate + CoA + H(+)
Catalysed by FAAH, PM20D1, BAAT
glycochenodeoxycholic acidReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. bile acid-CoA: amino acid N-acyltransferase
Catalysed by FAAH, PM20D1, BAATperoxisomeOne of 3 routes
glyoxylateReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. glycine + 2-oxoglutarate = glyoxylate + L-glutamate
Catalysed by FAAH, PM20D1, AADATOne of 11 routes
glycolithocholic acidReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. bile acid-CoA:amino acid N-acyltransferase (glycine)
Catalysed by FAAH, PM20D1, BAATcytosolOne of 2 routes
L-2-amino-3-oxobutanoic acidReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. Acetyl-CoA:glycine C-acetyltransferase
Catalysed by FAAH, PM20D1, GCATmitochondrial matrix
L-ornithineReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. L-Arginine:glycine amidinotransferase
Catalysed by FAAH, PM20D1, GATMcytosolOne of 5 routes
S(8)-aminomethyldihydrolipoamideReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. dihydrolipoyl dehydrogenase ([protein]-N6-(lipoyl)lysine)
Catalysed by FAAH, PM20D1, GLDC, GCSHmitochondrial matrix
2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerolReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
Catalysed by FAAH, PM20D1cytosol
(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoAReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + ATP + CoA = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate
Catalysed by FAAH, PM20D1, SLC27A2, ACSL4 and 9 more
prostaglandin H2Reach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. prostaglandin-endoperoxide synthase (arachidonate)
Catalysed by FAAH, PM20D1, PTGS1, PTGS2cytosolOne of 3 routes
sarcosineReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. sarcosine + O2 + H2O = formaldehyde + glycine + H2O2
Catalysed by FAAH, PM20D1, PIPOXOne of 2 routes
(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoateReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate
Catalysed by FAAH, PM20D1, ALOX5, ALOX15 and 1 more
(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoateReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate
Catalysed by FAAH, PM20D1, ALOX15B, ALOX15 and 1 more
(5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoateReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate
Catalysed by FAAH, PM20D1, ALOX5
(6S)-5,6,7,8-tetrahydrofolateReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine
Catalysed by FAAH, PM20D1, SHMT1, SHMT2
leukotriene A4Reach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = leukotriene A4 + H2O
Catalysed by FAAH, PM20D1, ALOX5
an N-acylglycineReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. an acyl-CoA + glycine = an N-acylglycine + CoA + H(+)
Catalysed by FAAH, PM20D1, GLYATL3, GLYAT and 1 more
guanidinoacetateReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. L-Arginine:glycine amidinotransferase
Catalysed by FAAH, PM20D1, GATMcytosolOne of 2 routes
L-methionineReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. transport of glycine and methionine (cytosol to extracellular)
Catalysed by FAAH, PM20D1, SLC7A5extracellular space, cytosolOne of 5 routes
L-tryptophanReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. transport of glycine and tryptophan (cytosol to extracellular)
Catalysed by FAAH, PM20D1, SLC7A5extracellular space, cytosolOne of 5 routes
glutathioneReach from here →
1. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
2. gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+)
Catalysed by FAAH, PM20D1, GSS