2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol

1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + O2 = 2-[15(S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-glycerol

Catalysed by ALOX15B

1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + O2 = 2-[12-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl]-glycerol

Catalysed by ALOX15B

1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O = glycerol + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)

Catalysed by FAAH, CES2, ABHD16A, EPHX1 and 7 more

1. fatty acid amide hydrolase (2-arachidonoylglycerol)

Catalysed by FAAHcytosolOne of 2 routes

1. phosphatidate phosphatase (1-lyso-2-arachidonoyl-phosphatidate)

Catalysed by PLPP1, PLPP3, PLPP2, LPIN1 and 7 morecytosolOne of 4 routes

1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 2 O2 = 2-glyceryl-prostaglandin G2

Catalysed by PTGS2

1. fatty acid amide hydrolase (2-arachidonoylglycerol)
2. Utilized Transport

Catalysed by FAAHcytosol, endoplasmic reticulumOne of 2 routes

1. fatty acid amide hydrolase (2-arachidonoylglycerol)
2. (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + 2 O2 = prostaglandin H2 + A + H2O

Catalysed by FAAH, PTGS1, PTGS2cytosolOne of 4 routes