L-2-amino-3-oxobutanoic acid

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

435 compounds within 3 steps: 1 in 1, 73 in 2, 361 in 3

One step

glycineReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
Catalysed by GCATmitochondrial matrix

Two steps

CHEBI:1146900Reach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. bile acid-CoA: amino acid N-acyltransferase
Catalysed by GCAT, BAATmitochondrial matrix, peroxisomeOne of 28 routes
N(omega)-methyl-L-arginineReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. N(omega)-methyl-L-arginine + glyoxylate = 5-(3-methylguanidino)-2-oxopentanoate + glycine
Catalysed by GCAT, AGXT2mitochondrial matrix
glycoursodeoxycholateReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. glycine to glycoursodeoxycholate conversion
Catalysed by GCATmitochondrial matrix, cytosolOne of 2 routes
N-(9Z-octadecenoyl)glycineReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. (9Z)-octadecenoyl-CoA + glycine = N-(9Z-octadecenoyl)glycine + CoA + H(+)
Catalysed by GCAT, GLYATL3, GLYATL2mitochondrial matrix
N-octadecanoylglycineReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. octadecanoyl-CoA + glycine = N-octadecanoylglycine + CoA + H(+)
Catalysed by GCAT, GLYATL2mitochondrial matrix
N-(9Z-hexadecenoyl)-glycineReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. (9Z)-hexadecenoyl-CoA + glycine = N-(9Z-hexadecenoyl)-glycine + CoA + H(+)
Catalysed by GCAT, GLYATL2mitochondrial matrix
N-hexadecanoylglycineReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. hexadecanoyl-CoA + glycine = N-hexadecanoylglycine + CoA + H(+)
Catalysed by GCAT, GLYATL3mitochondrial matrix
N-dodecanoylglycineReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. dodecanoyl-CoA + glycine = N-dodecanoylglycine + CoA + H(+)
Catalysed by GCAT, GLYATL2mitochondrial matrix
N-decanoylglycineReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. decanoyl-CoA + glycine = N-decanoylglycine + CoA + H(+)
Catalysed by GCAT, GLYATL2mitochondrial matrix
N-octanoylglycineReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. octanoyl-CoA + glycine = N-octanoylglycine + CoA + H(+)
Catalysed by GCAT, GLYATL2mitochondrial matrix
N(1)-(5-phospho-beta-D-ribosyl)glycinamideReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. 5-phospho-beta-D-ribosylamine + glycine + ATP = N(1)-(5-phospho-beta-D-ribosyl)glycinamide + ADP + phosphate + H(+)
Catalysed by GCAT, GARTmitochondrial matrix
L-cystine-bis-glycineReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. L-cystine-bis-glycine + 2 H2O = L-cystine + 2 glycine
Catalysed by GCAT, DPEP1, DPEP2mitochondrial matrix
glycyldehydrophenylalanineReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. glycyldehydrophenylalanine + H2O = 2,3-didehydrophenylalanine + glycine
Catalysed by GCAT, DPEP1mitochondrial matrix
an N-(fatty acyl)-glycineReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. a fatty acyl-CoA + glycine = an N-(fatty acyl)-glycine + CoA + H(+)
Catalysed by GCAT, GLYATL2mitochondrial matrix
N-(9Z,12Z-octadecadienoyl)-glycineReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. (9Z,12Z)-octadecadienoyl-CoA + glycine = N-(9Z,12Z-octadecadienoyl)-glycine + CoA + H(+)
Catalysed by GCAT, GLYATL2mitochondrial matrix
CHEBI:15570Reach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. transport of D-alanine and glycine (cytosol to extracellular)
Catalysed by GCAT, SLC3A2, SLC7A10mitochondrial matrix, extracellular space, cytosolOne of 2 routes
L-leucineReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. transport of glycine and leucine (cytosol to extracellular)
Catalysed by GCAT, SLC7A5mitochondrial matrix, extracellular space, cytosolOne of 5 routes
CHEBI:15611Reach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. S-Adenosyl-L-methionine:glycine N-methyltransferase
Catalysed by GCAT, GNMTmitochondrial matrix, cytosol
CHEBI:15699Reach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. transport of glycine and homoserine (cytosol to extracellular)
Catalysed by GCAT, SLC7A5mitochondrial matrix, extracellular space, cytosolOne of 4 routes
CHEBI:15971Reach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. transport of glycine and histidine (cytosol to extracellular)
Catalysed by GCAT, SLC7A6mitochondrial matrix, extracellular space, cytosolOne of 2 routes
L-citrullineReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. transport of citrulline and glycine (cytosol to extracellular)
Catalysed by GCAT, SLC7A9, SLC3A1, SLC7A6mitochondrial matrix, extracellular space, cytosol
L-valineReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. transport of glycine and valine (cytosol to extracellular)
Catalysed by GCAT, SLC7A5mitochondrial matrix, extracellular space, cytosolOne of 4 routes
L-arginineReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. transport of arginine and glycine (cytosol to extracellular)
Catalysed by GCAT, SLC7A6mitochondrial matrix, extracellular space, cytosolOne of 2 routes
CHEBI:16523Reach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. transport of D-serine and glycine (cytosol to extracellular)
Catalysed by GCAT, SLC3A2, SLC7A10mitochondrial matrix, extracellular space, cytosolOne of 2 routes
protein polypeptide chainReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. PROTEIN_BS
Catalysed by GCATmitochondrial matrix, cytosol
CHEBI:16856Reach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming)
Catalysed by GCAT, GSSmitochondrial matrix, cytosol
CHEBI:16857Reach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. transport of glycine and threonine (cytosol to extracellular)
Catalysed by GCAT, SLC3A2, SLC7A5, SLC7A10mitochondrial matrix, extracellular space, cytosolOne of 4 routes
glyoxylic acidReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. glycine:oxygen oxidoreductase (deaminating)
Catalysed by GCAT, DAOmitochondrial matrix, peroxisome
L-isoleucineReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. transport of glycine and isoleucine (cytosol to extracellular)
Catalysed by GCAT, SLC7A5mitochondrial matrix, extracellular space, cytosolOne of 4 routes
CHEBI:17203Reach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. transport of glycine and proline (cytosol to extracellular)
Catalysed by GCAT, SLC7A5, SLC7A6mitochondrial matrix, extracellular space, cytosolOne of 2 routes
5-aminolevulinic acidReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. succinyl-CoA:glycine C-succinyltransferase (decarboxylating)
Catalysed by GCAT, ALAS1, ALAS2, CPNE7mitochondrial matrix
L-cysteineReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. transport of cysteine and glycine (cytosol to extracellular)
Catalysed by GCAT, SLC3A2, SLC7A5, SLC7A8mitochondrial matrix, extracellular space, cytosolOne of 4 routes
CHEBI:17895Reach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. transport of glycine and tyrosine (cytosol to extracellular)
Catalysed by GCAT, SLC7A5mitochondrial matrix, extracellular space, cytosolOne of 4 routes
CHEBI:18019Reach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. transport of glycine and lysine (cytosol to extracellular)
Catalysed by GCAT, SLC7A6mitochondrial matrix, extracellular space, cytosolOne of 2 routes
L-glutamineReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. transport of glutamine and glycine (cytosol to extracellular)
Catalysed by GCAT, SLC7A5mitochondrial matrix, extracellular space, cytosolOne of 4 routes
N(1)-(5-phospho-D-ribosyl)glycinamideReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. 5-Phospho-D-ribosylamine:glycine ligase (ADP-forming)
Catalysed by GCAT, GARTmitochondrial matrix, cytosol
ophthalmateReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. gamma-L-glutamyl-(2S)-2-aminobutanoate + glycine + ATP = ophthalmate + ADP + phosphate + H(+)
Catalysed by GCAT, GSSmitochondrial matrix
N(omega),N('omega)-dimethyl-L-arginineReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. N(omega),N('omega)-dimethyl-L-arginine + glyoxylate = 5-(3,3'-dimethylguanidino)-2-oxopentanoate + glycine
Catalysed by GCAT, AGXT2mitochondrial matrix
5,6,7,8-tetrahydrofolic acidReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. 5,10-Methylenetetrahydrofolate:glycine hydroxymethyltransferase
Catalysed by GCAT, SHMT1mitochondrial matrix, cytosolOne of 2 routes
CHEBI:240943Reach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. glycine N-acyltransferase (2-methylbutyryl-CoA)
Catalysed by GCAT, GLYAT, GLYATL2, GLYATL1mitochondrial matrix
phenylacetylglycineReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. phenylacetyl-CoA:glycine N-phenylacetyltransferase
Catalysed by GCAT, GLYATmitochondrial matrix, cytosolOne of 3 routes
CHEBI:28666Reach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. LTD4 hydrolysis
Catalysed by GCATmitochondrial matrix, cytosol
Gly-tRNA(Gly)Reach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. glycine:tRNA(Gly) ligase (AMP-forming)
Catalysed by GCAT, GARS1mitochondrial matrix, cytosol
chlorine(.)Reach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. transport of chloride and glycine (cytosol to extracellular)
Catalysed by GCAT, SLC6A9, SLC6A14mitochondrial matrix, extracellular space, cytosolOne of 3 routes
glycocholateReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. bile acid-CoA: amino acid N-acyltransferase
Catalysed by GCAT, BAATmitochondrial matrix, peroxisomeOne of 3 routes
5-aminolevulinateReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. succinyl-CoA + glycine + H(+) = 5-aminolevulinate + CO2 + CoA
Catalysed by GCAT, ALAS1, ALAS2mitochondrial matrix
glycochenodeoxycholateReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. chenodeoxycholoyl-CoA + glycine = glycochenodeoxycholate + CoA + H(+)
Catalysed by GCAT, BAATmitochondrial matrix
glycochenodeoxycholic acidReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. bile acid-CoA: amino acid N-acyltransferase
Catalysed by GCAT, BAATmitochondrial matrix, peroxisomeOne of 3 routes
glyoxylateReach from here →
1. Acetyl-CoA:glycine C-acetyltransferase
2. glycine + 2-oxoglutarate = glyoxylate + L-glutamate
Catalysed by GCAT, AADATmitochondrial matrixOne of 11 routes