2-iminobutanoate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

85 compounds within 3 steps: 1 in 1, 12 in 2, 72 in 3

One step

2-oxobutanoateReach from here →
1. 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+)
Catalysed by RIDA

Two steps

2-hydroxybutyric acidReach from here →
1. 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+)
2. 2-hydroxybutyrate:NAD+ oxidoreductase
Catalysed by RIDA, LDHB, LDHC, LDHAL6A and 1 morecytosol
pyruvateReach from here →
1. 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+)
2. 2-oxobutanoate + L-alanine = (2S)-2-aminobutanoate + pyruvate
Catalysed by RIDA, AGXT2
propionyl-CoAReach from here →
1. 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+)
2. 2-oxobutyrate oxidation
Catalysed by RIDAcytosol
2-(alpha-Hydroxypropyl)thiamine diphosphateReach from here →
1. 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+)
2. branched chain keto acid dehydrogenase E1 (2-oxobutyrate)
Catalysed by RIDA, BCKDHA, BCKDHBmitochondrial matrix
5-(3,3-dimethylguanidino)-2-oxopentanoateReach from here →
1. 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+)
2. N(omega),N(omega)-dimethyl-L-arginine + 2-oxobutanoate = 5-(3,3-dimethylguanidino)-2-oxopentanoate + (2S)-2-aminobutanoate
Catalysed by RIDA, AGXT2
selenomethionineReach from here →
1. 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+)
2. Selenomethionine methanethiol-lyase (deaminating)
Catalysed by RIDA, CTHcytosol
CHEBI:27760Reach from here →
1. 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+)
2. Selenocystathionine Lysteine-lyase (deaminating)
Catalysed by RIDA, CTHcytosol
L-alpha-aminobutyric acidReach from here →
1. 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+)
2. glutamic-pyruvic transaminase ((S)-2-aminobutanoate)
Catalysed by RIDA, GPTcytosol
glyoxylateReach from here →
1. 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+)
2. (2S)-2-aminobutanoate + glyoxylate = 2-oxobutanoate + glycine
Catalysed by RIDA, AGXT2
L-threonineReach from here →
1. 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+)
2. L-threonine = 2-oxobutanoate + NH4(+)
Catalysed by RIDA, SDS, SDSL
kynurenateReach from here →
1. 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+)
2. 2-oxobutanoate + L-kynurenine = (2S)-2-aminobutanoate + kynurenate + H2O
Catalysed by RIDA, AADAT
(2S)-2-aminobutanoateReach from here →
1. 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+)
2. 2-oxobutanoate + L-kynurenine = (2S)-2-aminobutanoate + kynurenate + H2O
Catalysed by RIDA, AADATOne of 5 routes

Three steps

(S)-carnitineReach from here →
Catalysed by RIDAcytosol, mitochondrial matrixOne of 2 routes
CHEBI:1146900Reach from here →
Catalysed by RIDA, ACOT7cytosolOne of 13 routes

acetoacetate

Reach from here →

Catalysed by RIDA, LDHB, LDHC, LDHAL6A and 5 morecytosol, extracellular spaceOne of 6 routes

N-octanoyl-(2S)-hydroxyglycineReach from here →

Catalysed by RIDA, AGXT2, PAM

N-decanoyl-(2S)-hydroxyglycineReach from here →

Catalysed by RIDA, AGXT2, PAM

N-dodecanoyl-(2S)-hydroxyglycineReach from here →

Catalysed by RIDA, AGXT2, PAM

N-tetradecanoyl-(2S)-hydroxyglycineReach from here →

Catalysed by RIDA, AGXT2, PAM

N-(9Z-octadecenoyl)-(2S)-hydroxyglycineReach from here →

Catalysed by RIDA, AGXT2, PAM

N-(9Z,12Z,15Z)-octadecatrienoyl-(2S)-hydroxyglycineReach from here →

Catalysed by RIDA, AGXT2, PAM

acetaldehydeReach from here →

Catalysed by RIDA, SDS, SDSL, SHMT1

acetylpyruvateReach from here →

Catalysed by RIDA, AGXT2, FAHD1

all-trans-retinoic acidReach from here →

Catalysed by RIDA, LDHB, LDHC, LDHAL6A and 5 morecytosol, extracellular spaceOne of 4 routes

(S)-malateReach from here →

Catalysed by RIDA, AGXT2, CLYBLOne of 3 routes

2-methyl-3-oxopropanoic acidReach from here →

Catalysed by RIDA, AGXT2mitochondrial matrix

oxaloacetateReach from here →

Catalysed by RIDA, AGXT2One of 4 routes

CHEBI:16633Reach from here →

Catalysed by RIDA, CTHcytosol

(S)-lactateReach from here →

Catalysed by RIDA, AGXT2, LDHA, LDHB and 3 more

4-methylsulfanyl-2-oxobutanoateReach from here →

Catalysed by RIDA, AGXT2, AADAT

2-oxoglutaramateReach from here →

Catalysed by RIDA, AGXT2, KYAT1cytosolOne of 2 routes

3-fumarylpyruvateReach from here →

Catalysed by RIDA, AGXT2, FAHD1

(R)-3-hydroxybutyric acidReach from here →

Catalysed by RIDA, LDHB, LDHC, LDHAL6A and 7 morecytosol, extracellular spaceOne of 4 routes

3-hydroxypyruvateReach from here →

Catalysed by RIDA, AGXT2, AGXT

aceneuramateReach from here →

Catalysed by RIDA, AGXT2, NPL

5'-deoxyadenosineReach from here →

Catalysed by RIDA, AGXT2, TYW1B, TYW1

indole-3-pyruvateReach from here →

Catalysed by RIDA, AGXT2, AADAT

4-methyl-2-oxopentanoateReach from here →

Catalysed by RIDA, AGXT2, AADAT

3-phenylpyruvateReach from here →

Catalysed by RIDA, AGXT2, AADAT

L-glutamineReach from here →

Catalysed by RIDA, SDS, SDSL, SLC1A5inner side of the membrane, outer side of the membraneOne of 4 routes

dTDPReach from here →

Catalysed by RIDA, AGXT2, PKM, PKLRcytosol

gamma-L-glutamyl-(2S)-2-aminobutanoateReach from here →

Catalysed by RIDA, AADAT, GCLC

5-(3,3'-dimethylguanidino)-2-oxopentanoateReach from here →

Catalysed by RIDA, AGXT2One of 2 routes

5-(3-methylguanidino)-2-oxopentanoateReach from here →

Catalysed by RIDA, AGXT2One of 2 routes

2-oxopentanoateReach from here →

Catalysed by RIDA, AGXT2

a dicarboxylateReach from here →

Catalysed by RIDA, AADAT, SLC22A8inner side of the membrane, outer side of the membraneOne of 2 routes

glycolateReach from here →

Catalysed by RIDA, AGXT2, GRHPR

acetateReach from here →

Catalysed by RIDA, LDHB, LDHC, LDHAL6A and 5 morecytosol, extracellular spaceOne of 4 routes

oxalateReach from here →

Catalysed by RIDA, AGXT2, HAO1