selenomethionine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

85 compounds within 3 steps: 1 in 1, 12 in 2, 72 in 3

One step

2-oxobutanoateReach from here →
1. Selenomethionine methanethiol-lyase (deaminating)
Catalysed by CTHcytosol

Two steps

2-hydroxybutyric acidReach from here →
1. Selenomethionine methanethiol-lyase (deaminating)
2. 2-hydroxybutyrate:NAD+ oxidoreductase
Catalysed by CTH, LDHB, LDHC, LDHAL6A and 1 morecytosol
pyruvateReach from here →
1. Selenomethionine methanethiol-lyase (deaminating)
2. 2-oxobutanoate + L-alanine = (2S)-2-aminobutanoate + pyruvate
Catalysed by CTH, AGXT2cytosol
propionyl-CoAReach from here →
1. Selenomethionine methanethiol-lyase (deaminating)
2. 2-oxobutyrate oxidation
Catalysed by CTHcytosol
2-(alpha-Hydroxypropyl)thiamine diphosphateReach from here →
1. Selenomethionine methanethiol-lyase (deaminating)
2. branched chain keto acid dehydrogenase E1 (2-oxobutyrate)
Catalysed by CTH, BCKDHA, BCKDHBcytosol, mitochondrial matrix
5-(3,3-dimethylguanidino)-2-oxopentanoateReach from here →
1. Selenomethionine methanethiol-lyase (deaminating)
2. N(omega),N(omega)-dimethyl-L-arginine + 2-oxobutanoate = 5-(3,3-dimethylguanidino)-2-oxopentanoate + (2S)-2-aminobutanoate
Catalysed by CTH, AGXT2cytosol
CHEBI:27760Reach from here →
1. Selenomethionine methanethiol-lyase (deaminating)
2. Selenocystathionine Lysteine-lyase (deaminating)
Catalysed by CTHcytosol
L-alpha-aminobutyric acidReach from here →
1. Selenomethionine methanethiol-lyase (deaminating)
2. glutamic-pyruvic transaminase ((S)-2-aminobutanoate)
Catalysed by CTH, GPTcytosol
glyoxylateReach from here →
1. Selenomethionine methanethiol-lyase (deaminating)
2. (2S)-2-aminobutanoate + glyoxylate = 2-oxobutanoate + glycine
Catalysed by CTH, AGXT2cytosol
L-threonineReach from here →
1. Selenomethionine methanethiol-lyase (deaminating)
2. L-threonine = 2-oxobutanoate + NH4(+)
Catalysed by CTH, SDS, SDSLcytosol
kynurenateReach from here →
1. Selenomethionine methanethiol-lyase (deaminating)
2. 2-oxobutanoate + L-kynurenine = (2S)-2-aminobutanoate + kynurenate + H2O
Catalysed by CTH, AADATcytosol
(2S)-2-aminobutanoateReach from here →
1. Selenomethionine methanethiol-lyase (deaminating)
2. 2-oxobutanoate + L-kynurenine = (2S)-2-aminobutanoate + kynurenate + H2O
Catalysed by CTH, AADATcytosolOne of 5 routes
2-iminobutanoateReach from here →
1. Selenomethionine methanethiol-lyase (deaminating)
2. 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+)
Catalysed by CTH, RIDAcytosol

Three steps

(S)-carnitineReach from here →
Catalysed by CTHcytosol, mitochondrial matrixOne of 2 routes
CHEBI:1146900Reach from here →
Catalysed by CTH, ACOT7cytosolOne of 13 routes

acetoacetate

Reach from here →

Catalysed by CTH, LDHB, LDHC, LDHAL6A and 5 morecytosol, extracellular spaceOne of 6 routes

N-octanoyl-(2S)-hydroxyglycineReach from here →

Catalysed by CTH, AGXT2, PAMcytosol

N-decanoyl-(2S)-hydroxyglycineReach from here →

Catalysed by CTH, AGXT2, PAMcytosol

N-dodecanoyl-(2S)-hydroxyglycineReach from here →

Catalysed by CTH, AGXT2, PAMcytosol

N-tetradecanoyl-(2S)-hydroxyglycineReach from here →

Catalysed by CTH, AGXT2, PAMcytosol

N-(9Z-octadecenoyl)-(2S)-hydroxyglycineReach from here →

Catalysed by CTH, AGXT2, PAMcytosol

N-(9Z,12Z,15Z)-octadecatrienoyl-(2S)-hydroxyglycineReach from here →

Catalysed by CTH, AGXT2, PAMcytosol

acetaldehydeReach from here →

Catalysed by CTH, SDS, SDSL, SHMT1cytosol

acetylpyruvateReach from here →

Catalysed by CTH, AGXT2, FAHD1cytosol

all-trans-retinoic acidReach from here →

Catalysed by CTH, LDHB, LDHC, LDHAL6A and 5 morecytosol, extracellular spaceOne of 4 routes

(S)-malateReach from here →

Catalysed by CTH, AGXT2, CLYBLcytosolOne of 3 routes

2-methyl-3-oxopropanoic acidReach from here →

Catalysed by CTH, AGXT2cytosol, mitochondrial matrix

oxaloacetateReach from here →

Catalysed by CTH, AGXT2cytosolOne of 4 routes

CHEBI:16633Reach from here →

Catalysed by CTHcytosol

(S)-lactateReach from here →

Catalysed by CTH, AGXT2, LDHA, LDHB and 3 morecytosol

4-methylsulfanyl-2-oxobutanoateReach from here →

Catalysed by CTH, AGXT2, AADATcytosol

2-oxoglutaramateReach from here →

Catalysed by CTH, AGXT2, KYAT1cytosolOne of 2 routes

3-fumarylpyruvateReach from here →

Catalysed by CTH, AGXT2, FAHD1cytosol

(R)-3-hydroxybutyric acidReach from here →

Catalysed by CTH, LDHB, LDHC, LDHAL6A and 7 morecytosol, extracellular spaceOne of 4 routes

3-hydroxypyruvateReach from here →

Catalysed by CTH, AGXT2, AGXTcytosol

aceneuramateReach from here →

Catalysed by CTH, AGXT2, NPLcytosol

5'-deoxyadenosineReach from here →

Catalysed by CTH, AGXT2, TYW1B, TYW1cytosol

indole-3-pyruvateReach from here →

Catalysed by CTH, AGXT2, AADATcytosol

4-methyl-2-oxopentanoateReach from here →

Catalysed by CTH, AGXT2, AADATcytosol

3-phenylpyruvateReach from here →

Catalysed by CTH, AGXT2, AADATcytosol

L-glutamineReach from here →

Catalysed by CTH, SDS, SDSL, SLC1A5cytosol, inner side of the membrane, outer side of the membraneOne of 4 routes

dTDPReach from here →

Catalysed by CTH, AGXT2, PKM, PKLRcytosol

gamma-L-glutamyl-(2S)-2-aminobutanoateReach from here →

Catalysed by CTH, AADAT, GCLCcytosol

5-(3,3'-dimethylguanidino)-2-oxopentanoateReach from here →

Catalysed by CTH, AGXT2cytosolOne of 2 routes

5-(3-methylguanidino)-2-oxopentanoateReach from here →

Catalysed by CTH, AGXT2cytosolOne of 2 routes

2-oxopentanoateReach from here →

Catalysed by CTH, AGXT2cytosol

a dicarboxylateReach from here →

Catalysed by CTH, AADAT, SLC22A8cytosol, inner side of the membrane, outer side of the membraneOne of 2 routes

glycolateReach from here →

Catalysed by CTH, AGXT2, GRHPRcytosol

acetateReach from here →

Catalysed by CTH, LDHB, LDHC, LDHAL6A and 5 morecytosol, extracellular spaceOne of 4 routes

oxalateReach from here →

Catalysed by CTH, AGXT2, HAO1cytosol