Compound
superoxide
Highly reactive compounds produced when oxygen is reduced by a single electron. In biological systems, they may be generated during the normal catalytic function of a number of enzymes and during the oxidation of hemoglobin to methemoglobin. In living organisms, superoxide dismutase protects the cell from the deleterious effects of superoxides.
Structure
No three-dimensional record for this entry.
- Class
- Element, as a monatomic anion
- Formula
- O2
- Mass
- 31.998 g/mol
- Charge
- -1
- InChIKey
- OUUQCZGPVNCOIJ-UHFFFAOYSA-M
- SMILES
- [O][O-]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
9 entities
9 entities reached.
0 reported hops9 assembled from the scaffold
- SOD1ProteinUNIPROT:P00441substrate ofInferred only160 paths40 endpoints
- SOD2ProteinUNIPROT:P04179substrate ofInferred only105 paths35 endpoints
- SOD3ProteinUNIPROT:P08294substrate ofInferred only51 paths17 endpoints
- CYBBProteinUNIPROT:P04839substrate ofInferred only48 paths48 endpoints
- NOX1ProteinUNIPROT:Q9Y5S8substrate ofInferred only27 paths27 endpoints
- NOX4ProteinUNIPROT:Q9NPH5substrate ofInferred only22 paths22 endpoints
- NOX5ProteinUNIPROT:Q96PH1substrate ofInferred only10 paths5 endpoints
- NOX3ProteinUNIPROT:Q9HBY0substrate ofInferred only10 paths10 endpoints
- CYGBProteinUNIPROT:Q8WWM9substrate ofInferred only5 paths5 endpoints
What the reference databases state
Statements
17 statements
17 statements · 2 reference databases · Subject: superoxide · Sources: Human-GEM, Rhea
- superoxide is a substrate of CYBBProteinRhea RHEA:63180Inferred only
- superoxide is a substrate of CYGBProteinRhea RHEA:20696Inferred only
- superoxide is a substrate of NOX1ProteinRhea RHEA:63180Inferred only
- superoxide is a substrate of NOX3ProteinRhea RHEA:63180Inferred only
- superoxide is a substrate of NOX4ProteinRhea RHEA:63180Inferred only
- superoxide is a substrate of NOX5ProteinRhea RHEA:63180Inferred only
- superoxide is a substrate of NOX5ProteinRhea RHEA:86239Inferred only
- superoxide is a substrate of SOD1ProteinRhea RHEA:20696Inferred only
- superoxide is a substrate of SOD1ProteinHuman-GEM MAR08415Inferred only
- superoxide is a substrate of SOD1ProteinHuman-GEM MAR08413Inferred only
- superoxide is a substrate of SOD1ProteinHuman-GEM MAR03960Inferred only
- superoxide is a substrate of SOD2ProteinRhea RHEA:20696Inferred only
Show the remaining 5
- superoxide is a substrate of SOD2ProteinHuman-GEM MAR03960Inferred only
- superoxide is a substrate of SOD2ProteinHuman-GEM MAR08410Inferred only
- superoxide is a substrate of SOD3ProteinRhea RHEA:20696Inferred only
- superoxide is a substrate of SOD3ProteinHuman-GEM MAR03960Inferred only
- superoxide is a substrate of SOD3ProteinHuman-GEM MAR08409Inferred only
Reactions
46 reactions
(5Z,8Z,11Z,14Z)-eicosatetraenoate+superoxideMAM01246c+proton
Reaction pageLeft to rightUnbalancedcytosol
Human-GEM MAR01358CC BY 4.0Reference data
(5Z,8Z,11Z,14Z)-eicosatetraenoate+superoxideMAM00302c+proton
Reaction pageLeft to rightUnbalancedcytosol
Human-GEM MAR01361CC BY 4.0Reference data
(5Z,8Z,11Z,14Z)-eicosatetraenoate+superoxideMAM00335c+proton
Reaction pageLeft to rightUnbalancedcytosol
Human-GEM MAR01364CC BY 4.0Reference data
MAM01198c+protonall-cis-docosa-4,7,10,13,16,19-hexaenoic acid+superoxide
Reaction pageReversibleUnbalancedcytosol
Human-GEM MAR01403CC BY 4.0Reference data
MAM01215c+protonall-cis-docosa-4,7,10,13,16,19-hexaenoic acid+superoxide
Reaction pageReversibleUnbalancedcytosol
Human-GEM MAR01404CC BY 4.0Reference data
all-cis-docosa-4,7,10,13,16,19-hexaenoic acid+superoxideMAM00275c+proton
Reaction pageLeft to rightUnbalancedcytosol
Human-GEM MAR01405CC BY 4.0Reference data
11-cis-retinyl hexadecanoate+protonall-cis-docosa-4,7,10,13,16,19-hexaenoic acid+superoxide
Reaction pageReversibleUnbalancedcytosol
Human-GEM MAR01406CC BY 4.0Reference data
MAM00372c+protonall-cis-docosa-4,7,10,13,16,19-hexaenoic acid+superoxide
Reaction pageReversibleUnbalancedcytosol
Human-GEM MAR01407CC BY 4.0Reference data
MAM00404c+protonall-cis-docosa-4,7,10,13,16,19-hexaenoic acid+superoxide
Reaction pageReversibleUnbalancedcytosol
Human-GEM MAR01408CC BY 4.0Reference data
MAM00418c+protonall-cis-docosa-4,7,10,13,16,19-hexaenoic acid+superoxide
Reaction pageReversibleUnbalancedcytosol
Human-GEM MAR01409CC BY 4.0Reference data
MAM01792c+dioxygenMAM01791c+proton+superoxide
Reaction pageLeft to rightBalancedcytosol
Human-GEM MAR02064CC BY 4.0Reference data
MAM01794c+dioxygenMAM01793c+proton+superoxide
Reaction pageLeft to rightBalancedcytosol
Human-GEM MAR02079CC BY 4.0Reference data
Other names
18 names
Resolves to: superoxide
- Also called
- (O2)(.-)(O2)•−dioxide(1-)dioxide(1−)hyperoxideO2-O2.-O2(-)O2(.-)O2•−O2−Superoxide anionsuperoxide anion radicalsuperoxide radicalsuperoxide radical anion
- Systematic name
- dioxidanidyldioxide(.1-)dioxide(•1−)