Compound
D-mannose 6-phosphate
A D-hexopyranose 6-phosphate(2−) that is the dianion of D-mannopyranose 6-phosphate arising from deprotonation of the phosphate function.
Definition from ChEBI (CHEBI:58735), read 2026-09-23. CC BY 4.0.
Structure
Loading the model…
- Class
- Organic compound, anion
- Formula
- C6H11O9P
- Mass
- 258.119 g/mol
- Charge
- -2
- InChIKey
- NBSCHQHZLSJFNQ-QTVWNMPRSA-L
- SMILES
- O=P([O-])([O-])OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
4 entities
4 entities reached.
0 reported hops4 assembled from the scaffold
What the reference databases state
Statements
13 statements
13 statements · 1 reference database · Subject: D-mannose 6-phosphate · Sources: Rhea
- alpha-D-mannose 1-phosphate is converted to D-mannose 6-phosphateCompoundRhea RHEA:11140Inferred only
- D-mannose 6-phosphate is converted to alpha-D-mannose 1-phosphateCompoundRhea RHEA:11140Inferred only
- D-fructose 6-phosphate is converted to D-mannose 6-phosphateCompoundRhea RHEA:12356Inferred only
- D-mannose 6-phosphate is converted to D-fructose 6-phosphateCompoundRhea RHEA:12356Inferred only
- D-glucose 6-phosphate is converted to D-mannose 6-phosphateCompoundRhea RHEA:85575Inferred only
- D-mannose 6-phosphate is converted to D-glucose 6-phosphateCompoundRhea RHEA:85575Inferred only
- D-mannose is converted to D-mannose 6-phosphateCompoundRhea RHEA:11028Inferred only
- D-mannose is converted to D-mannose 6-phosphateCompoundRhea RHEA:28554Inferred only
- D-mannose 6-phosphate is converted to D-mannoseCompoundRhea RHEA:28554Inferred only
- D-mannose 6-phosphate is a substrate of GPIProteinRhea RHEA:85575Inferred only
- D-mannose 6-phosphate is a substrate of MPIProteinRhea RHEA:12356Inferred only
- D-mannose 6-phosphate is a substrate of PMM1ProteinRhea RHEA:11140Inferred only
Show the remaining 1
- D-mannose 6-phosphate is a substrate of PMM2ProteinRhea RHEA:11140Inferred only
Reactions
8 reactions
D-mannose+ATP(4-)D-mannose 6-phosphate+ADP(3-)+hydron
Reaction pageLeft to rightBalanced
Rhea RHEA:11028CC BY 4.0Reference data
alpha-D-mannose 1-phosphateD-mannose 6-phosphate
Reaction pageDirection not assertedBalanced
Rhea RHEA:11140CC BY 4.0Reference data
D-mannose 6-phosphateD-fructose 6-phosphate
Catalysed by MPI
Reaction pageDirection not assertedBalanced
Rhea RHEA:12356CC BY 4.0Reference data
CHEBI:61381+NADP(3-)D-mannose 6-phosphate+NADPH(4-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:14925CC BY 4.0Reference data
D-mannose 6-phosphate+waterD-mannose+hydrogenphosphate
Reaction pageDirection not assertedBalanced
Rhea RHEA:28554CC BY 4.0Reference data
D-mannose+N(pros)-phospho-L-histidyl-[protein]D-mannose 6-phosphate+L-histidyl-[protein]
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:49232CC BY 4.0Reference data
D-mannose 6-phosphateCHEBI:232323+hydrogenphosphate
Reaction pageDirection not assertedBalanced
Rhea RHEA:82407CC BY 4.0Reference data
D-glucose 6-phosphateD-mannose 6-phosphate
Catalysed by GPI
Reaction pageReversibleBalanced
Rhea RHEA:85575CC BY 4.0Reference data
Other names
2 names
Resolves to: D-mannose 6-phosphate
- Systematic name
- 6-O-phosphonato-D-mannopyranoseD-mannopyranose 6-phosphate