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1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

367 compounds within 3 steps: 7 in 1, 60 in 2, 300 in 3

Does it reach a compound?

Two steps

1-octadecanoyl-2-acetyl-sn-glycero-3-phosphocholineReach from here →
1. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine
2. 1-octadecanoyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-octadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + CoA
Catalysed by PLA2G15, LPCAT2
1-acyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
2. a 1-acyl-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA = 1-acyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by LPGAT1, LPCAT4
1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerolReach from here →
1. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoate + H(+)
2. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + octadecanoate + H(+)
Catalysed by PNPLA8, ABHD11
1-octadecanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
1. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
2. 2-(9Z-octadecenoyl)-glycerol + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by LPGAT1, MOGAT2, MOGAT1
hexadecyl octadecanoateReach from here →
1. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
2. hexadecan-1-ol + octadecanoyl-CoA = hexadecyl octadecanoate + CoA
Catalysed by LPGAT1, AWAT1, AWAT2
(R)-3-hydroxy-(11Z)-octadecenoyl-CoAReach from here →
1. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
2. Fatty Acid Beta Oxidation (C18:1->C18:1Oh), Mitochondrial
Catalysed by LPGAT1, HADHA, ACADVLmitochondrial matrix
1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerolReach from here →
1. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoate + H(+)
2. 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + H2O = 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-glycerol + octadecanoate + H(+)
Catalysed by PNPLA8, ABHD11
1-O-(1Z)-alkenyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
2. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA = 1-O-(1Z)-alkenyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by LPGAT1, LPCAT4
N-(9Z-octadecenoyl)-sphing-4-enineReach from here →
1. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoate + H(+)
2. N-(9Z-octadecenoyl)-sphing-4-enine + H2O = sphing-4-enine + (9Z)-octadecenoate
Catalysed by PNPLA8, ASAH1, ACER2, ACER1 and 2 more
18-hydroxy-(9Z)-octadecenoateReach from here →
1. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoate + H(+)
2. (9Z)-octadecenoate + reduced [NADPH--hemoprotein reductase] + O2 = 18-hydroxy-(9Z)-octadecenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by PNPLA8, CYP4A11, CYP4F11
1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol)Reach from here →
1. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoate + H(+)
2. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = sn-glycero-3-phospho-1D-myo-inositol + (9Z)-octadecenoate + H(+)
Catalysed by PNPLA8, ABHD12
cholesteryl octadecanoateReach from here →
1. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
2. Acyl-CoA:cholesterol O-acyltransferase
Catalysed by LPGAT1, SOAT2, SOAT1endoplasmic reticulumOne of 2 routes
N-octadecanoylhexadecasphinganineReach from here →
1. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
2. hexadecasphinganine + octadecanoyl-CoA = N-octadecanoylhexadecasphinganine + CoA + H(+)
Catalysed by LPGAT1, CERS1, CERS4
a 1-acyl-2-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol)Reach from here →
1. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
2. a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + octadecanoyl-CoA = a 1-acyl-2-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA
Catalysed by LPGAT1, LCLAT1
O-octadecanoyl-(R)-carnitineReach from here →
1. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
2. (R)-carnitine + octadecanoyl-CoA = O-octadecanoyl-(R)-carnitine + CoA
Catalysed by LPGAT1, CPT2
1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholineReach from here →
1. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
2. 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by LPGAT1
1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholineReach from here →
1. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
2. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by LPGAT1

Three steps

CHEBI:1307929Reach from here →
Catalysed by LPGAT1, SOAT2, SOAT1, CEL and 1 moreendoplasmic reticulum, lysosomeOne of 2 routes
(5E)-tetradecenoyl-(R)-carnitineReach from here →

Page 2 of 8

Catalysed by PNPLA8, CPT1A, CPT1C, CPT1Bendoplasmic reticulum, cytosolOne of 7 routes

an acyl-4'-phosphopantetheineReach from here →

2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
acyl-CoA pool formation and breakdown
an acyl-CoA + H2O = an acyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Catalysed by LPGAT1, NUDT19, FITM2, NUDT8cytosol

1-(9Z-octadecenoyl)-3-(9Z,12Z-octadecadienoyl)-glycerolReach from here →

1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoate + H(+)
(9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
1-(9Z,12Z-octadecadienoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-(9Z-octadecenoyl)-3-(9Z,12Z-octadecadienoyl)-glycerol + CoA

Catalysed by PNPLA8, SLC27A2, ACSL3, ACSL1 and 7 more

N-(9Z-octadecenoyl)glycineReach from here →

1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoate + H(+)
(9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
(9Z)-octadecenoyl-CoA + glycine = N-(9Z-octadecenoyl)glycine + CoA + H(+)

Catalysed by PNPLA8, SLC27A2, ACSL3, ACSL1 and 7 more

9-(9Z-octadecenoyloxy)-octadecanoateReach from here →

1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoate + H(+)
1,2-di-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+) = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O
1,2,3-tri-(9Z-octadecenoyl)-glycerol + 9-hydroxy-octadecanoate = 9-(9Z-octadecenoyloxy)-octadecanoate + 2,3-di-(9Z)-octadecenoyl-sn-glycerol

Catalysed by PNPLA8, DGAT1, LIPA, PNPLA4 and 2 more

1-O-(9Z-octadecenyl)-2,3-di-(9Z-octadecenoyl)glycerolReach from here →

1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoate + H(+)
(9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-O-(9Z-octadecenyl)-2,3-di-(9Z-octadecenoyl)glycerol + CoA

Catalysed by PNPLA8, SLC27A2, ACSL3, ACSL1 and 8 more

beta-D-glucosyl-N-(9Z-octadecenoyl)-sphing-4E-enineReach from here →

1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoate + H(+)
N-(9Z-octadecenoyl)-sphing-4-enine + H2O = sphing-4-enine + (9Z)-octadecenoate
beta-D-glucosyl-N-(9Z-octadecenoyl)-sphing-4E-enine + cholesterol = N-(9Z-octadecenoyl)-sphing-4-enine + cholesteryl 3-beta-D-glucoside

Catalysed by PNPLA8, ASAH1, ACER2, ACER1 and 4 more

1-octadecanoyl-2-(15-hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoyl)-sn-glycero-3-phosphocholineReach from here →

1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine
1-octadecanoyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA
1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + O2 = 1-octadecanoyl-2-(15-hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoyl)-sn-glycero-3-phosphocholine

Catalysed by PLA2G15, LPCAT3, ALOX15B

cholesteryl (7Z)-octadecenoateReach from here →

2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
stearoyl-CoA 9-desaturase (stearoyl-CoA)
(7Z)-octadecenoyl-CoA + cholesterol = cholesteryl (7Z)-octadecenoate + CoA

Catalysed by LPGAT1, SCD, SCD5, SOAT1cytosol

CHEBI:15345Reach from here →

2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
Stearoyl-CoA hydrolase
Acetoacetate:CoA ligase (AMP-forming)

Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 3 morecytosolOne of 2 routes

acetylcholineReach from here →

1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine
1-octadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphate + choline + H(+)
Acetyl-CoA:choline O-acetyltransferase

Catalysed by PLA2G15, ENPP2, CHATcytosolOne of 3 routes

CHEBI:15380Reach from here →

2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
Stearoyl-CoA hydrolase
5-aminolevulinate synthase (2-amino-3-oxoadipate)

Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 4 morecytosol, mitochondrial matrixOne of 8 routes

CHEBI:15477Reach from here →

2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
Stearoyl-CoA hydrolase
glycine N-acyltransferase (2-methylbutyryl-CoA)

Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 5 morecytosol, mitochondrial matrixOne of 2 routes

2-methylcrotonoyl-CoAReach from here →

2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
Stearoyl-CoA hydrolase
Production of Tiglylcarnitine

Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 4 morecytosolOne of 2 routes

isobutyryl-CoAReach from here →

2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
Stearoyl-CoA hydrolase
acetyl-CoA C-acyltransferase (3-oxo-4-methyl-pentanoyl-CoA)

Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 5 morecytosol, mitochondrial matrixOne of 3 routes

3-methylbut-2-enoyl-CoAReach from here →

2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
Stearoyl-CoA hydrolase
glycine-N-acyltransferase (3-methylcrotonoylglycine)

Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 3 morecytosol, mitochondrial matrix

isovaleryl-CoAReach from here →

2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
Stearoyl-CoA hydrolase
glycine N-acyltransferase (isovalerylglycine)

Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 5 morecytosol, mitochondrial matrixOne of 3 routes

arachidonoyl-CoAReach from here →

2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
Stearoyl-CoA hydrolase
Arachidonate:CoA ligase (AMP-forming)

Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 10 morecytosolOne of 12 routes

CHEBI:15519Reach from here →

2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
Stearoyl-CoA hydrolase
propanoyl-CoA C-acyltransferase

Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 5 morecytosol, peroxisomeOne of 2 routes

phenylacetyl-CoAReach from here →

2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
Stearoyl-CoA hydrolase
Phenylacetate:CoA ligase

Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 2 morecytosolOne of 3 routes

propionyl-CoAReach from here →

1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoate + H(+)
Utilized Transport
Active Transport

Catalysed by PNPLA8endoplasmic reticulum, cytosol, mitochondrial matrixOne of 45 routes

L-leucineReach from here →

1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoate + H(+)
N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate
N-(9Z-octadecenoyl)-L-leucine + H2O = L-leucine + (9Z)-octadecenoate

Catalysed by PNPLA8, PM20D1

1-(10Z-heptadecenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamineReach from here →

1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoate + H(+)
(9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
1-(10Z-heptadecenoyl)-sn-glycero-3-phosphoethanolamine + (9Z)-octadecenoyl-CoA = 1-(10Z-heptadecenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA

Catalysed by PNPLA8, SLC27A2, ACSL3, ACSL1 and 6 more

CHEBI:15650Reach from here →

2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
Stearoyl-CoA hydrolase
N-acetyl-LTE4 to leukotriene E4 conversion

Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 34 morecytosolOne of 2 routes

S-(9Z-octadecenoyl)-4'-phosphopantetheineReach from here →

1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoate + H(+)
(9Z)-octadecenoate + ATP + CoA = (9Z)-octadecenoyl-CoA + AMP + diphosphate
(9Z)-octadecenoyl-CoA + H2O = S-(9Z-octadecenoyl)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)

Catalysed by PNPLA8, SLC27A2, ACSL3, ACSL1 and 6 more

betaine aldehydeReach from here →

1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine
1-octadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphate + choline + H(+)
choline dehydrogenase (choline)

Catalysed by PLA2G15, ENPP2, CHDHcytosolOne of 3 routes

CHEBI:15727Reach from here →

2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
Stearoyl-CoA hydrolase
N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)

Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 3 morecytosol

CHEBI:15746Reach from here →

2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
Stearoyl-CoA hydrolase
diamine N-acetyltransferase (N1-acetylspermine)

Catalysed by LPGAT1, ACOT7, BAAT, THEM4 and 4 morecytosolOne of 2 routes

hexadecanoic acidReach from here →

1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoate + H(+)
(10Z)-heptadecenoic acid formation
(10Z)-heptadecenoic acid formation

Catalysed by PNPLA8cytosol, extracellular spaceOne of 16 routes

1-acylglycerone 3-phosphateReach from here →

2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
acyl-CoA pool formation and breakdown
Acyl-CoA:glycerone-phosphate O-acyltransferase

Catalysed by LPGAT1, GNPATcytosol

CHEBI:15978Reach from here →

1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine
1-octadecanoyl-sn-glycero-3-phosphocholine + H2O = octadecanoate + sn-glycerol 3-phosphocholine + H(+)
sn-Glycero-3-phosphocholine glycerophosphohydrolase

Catalysed by PLA2G15, LYPLA2, ASPG, GPCPD1cytosol

phosphatidylethanolamineReach from here →

2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
acyl-CoA pool formation and breakdown
Acyl-CoA:1-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase

Catalysed by LPGAT1, LPCAT4, LPCAT3, LPCAT2 and 1 morecytosol