4-aminobutanal

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

58 compounds within 3 steps: 1 in 1, 6 in 2, 51 in 3

One step

4-aminobutanoateReach from here →
1. 4-aminobutanal + NAD(+) + H2O = 4-aminobutanoate + NADH + 2 H(+)
Catalysed by ALDH1A1, ALDH9A1

Two steps

L-homocarnosineReach from here →
1. 4-aminobutanal + NAD(+) + H2O = 4-aminobutanoate + NADH + 2 H(+)
2. Formation of homocarnosine
Catalysed by ALDH1A1, ALDH9A1, CARNS1cytosolOne of 2 routes
succinic semialdehydeReach from here →
1. 4-aminobutanal + NAD(+) + H2O = 4-aminobutanoate + NADH + 2 H(+)
2. 4-aminobutanoate:2-oxoglutarate aminotransferase
Catalysed by ALDH1A1, ALDH9A1, ABATmitochondrial matrix
chlorine(.)Reach from here →
1. 4-aminobutanal + NAD(+) + H2O = 4-aminobutanoate + NADH + 2 H(+)
2. transport of 4-aminobutyrate and chloride (cytosol to extracellular)
Catalysed by ALDH1A1, ALDH9A1, SLC6A12extracellular space, cytosolOne of 4 routes
L-ornithineReach from here →
1. 4-aminobutanal + NAD(+) + H2O = 4-aminobutanoate + NADH + 2 H(+)
2. 4-aminobutanoate + L-arginine = 4-guanidinobutanoate + L-ornithine
Catalysed by ALDH1A1, ALDH9A1, GATM
4-guanidinobutanoateReach from here →
1. 4-aminobutanal + NAD(+) + H2O = 4-aminobutanoate + NADH + 2 H(+)
2. 4-aminobutanoate + L-arginine = 4-guanidinobutanoate + L-ornithine
Catalysed by ALDH1A1, ALDH9A1, GATM
succinate semialdehydeReach from here →
1. 4-aminobutanal + NAD(+) + H2O = 4-aminobutanoate + NADH + 2 H(+)
2. 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate
Catalysed by ALDH1A1, ALDH9A1, ABAT

Three steps

Catalysed by ALDH1A1, ALDH9A1, GATM, SLC25A2

inner side of the membrane, outer side of the membrane

One of 2 routes

L-homoarginineReach from here →

Catalysed by ALDH1A1, ALDH9A1, GATM, SLC25A2inner side of the membrane, outer side of the membraneOne of 2 routes

cholineReach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12, SLC5A7extracellular space, cytosol

L-leucineReach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12, SLC6A14extracellular space, cytosolOne of 6 routes

CHEBI:15699Reach from here →

Catalysed by ALDH1A1, ALDH9A1, GATM, SLC7A6extracellular space, cytosolOne of 2 routes

CHEBI:15971Reach from here →

Catalysed by ALDH1A1, ALDH9A1, CARNS1, CNDP1 and 1 morecytosolOne of 6 routes

sulfateReach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12, SLC26A6extracellular space, cytosol

ureaReach from here →

Catalysed by ALDH1A1, ALDH9A1, GATM, AGMAT

L-citrullineReach from here →

Catalysed by ALDH1A1, ALDH9A1, GATM, SLC7A9extracellular space, cytosolOne of 9 routes

iodideReach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12, SLC26A4extracellular space, cytosol

L-valineReach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12, SLC6A14extracellular space, cytosolOne of 4 routes

L-arginineReach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12, SLC6A14extracellular space, cytosolOne of 9 routes

N(2)-acetyl-L-ornithineReach from here →

Catalysed by ALDH1A1, ALDH9A1, GATM, ACY1cytosol

4-hydroxybutanoateReach from here →

Catalysed by ALDH1A1, ALDH9A1, ABATmitochondrial matrixOne of 3 routes

CHEBI:16857Reach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12, SLC6A14extracellular space, cytosolOne of 3 routes

oxalic acidReach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12, SLC26A6extracellular space, cytosol

L-isoleucineReach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12, SLC6A14extracellular space, cytosolOne of 4 routes

CHEBI:17203Reach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12, CLTRN and 1 moreextracellular space, cytosolOne of 4 routes

L-glutamic 5-semialdehydeReach from here →

Catalysed by ALDH1A1, ALDH9A1, GATM, OATmitochondrial matrix

L-cysteineReach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12, SLC6A14extracellular space, cytosolOne of 4 routes

glycine betaineReach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12extracellular space, cytosolOne of 3 routes

CHEBI:17895Reach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12, SLC6A14extracellular space, cytosolOne of 4 routes

CHEBI:18019Reach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12, SLC6A14extracellular space, cytosolOne of 5 routes

L-glutamineReach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12, SLC6A14extracellular space, cytosolOne of 3 routes

CHEBI:18095Reach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12, CLTRN and 1 moreextracellular space, cytosol

N-carbamoyl-beta-alanineReach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12extracellular space, cytosolOne of 2 routes

CHEBI:240943Reach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12, SLC6A5extracellular space, cytosolOne of 2 routes

hypochlorous acidReach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12, LPOextracellular space, cytosolOne of 4 routes

potassium atomReach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12, SLC12A2 and 1 moreextracellular space, cytosolOne of 2 routes

Ca(2+)Reach from here →

Catalysed by ALDH1A1, ALDH9A1, CARNS1cytosol, extracellular spaceOne of 2 routes

formic acidReach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12, SLC26A4extracellular space, cytosolOne of 2 routes

malonic acidReach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12extracellular space, cytosolOne of 2 routes

L-lysineReach from here →

Catalysed by ALDH1A1, ALDH9A1, GATM, SLC25A2 and 1 moreinner side of the membrane, outer side of the membraneOne of 2 routes

D-lysineReach from here →

Catalysed by ALDH1A1, ALDH9A1, GATM, SLC25A2inner side of the membrane, outer side of the membraneOne of 2 routes

putrescineReach from here →

Catalysed by ALDH1A1, ALDH9A1, GATM, ODC1cytosolOne of 3 routes

D-arginineReach from here →

Catalysed by ALDH1A1, ALDH9A1, GATM, SLC25A2inner side of the membrane, outer side of the membraneOne of 2 routes

taurineReach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12, SLC6A6extracellular space, cytosolOne of 2 routes

glycineReach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12, SLC6A9 and 1 moreextracellular space, cytosolOne of 7 routes

L-histidineReach from here →

Catalysed by ALDH1A1, ALDH9A1, CARNS1, CNDP1cytosolOne of 3 routes

D-ornithineReach from here →

Catalysed by ALDH1A1, ALDH9A1, GATM, SLC25A2inner side of the membrane, outer side of the membraneOne of 2 routes

guanidinoacetateReach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12extracellular space, cytosol

L-methionineReach from here →

Catalysed by ALDH1A1, ALDH9A1, SLC6A12, SLC6A14extracellular space, cytosolOne of 4 routes