L-asparagine
362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API
946 compounds within 3 steps: 24 in 1, 287 in 2, 635 in 3
Two steps
No catalyst recordedextracellular space, cytosolOne of 2 routes
- N-acetylglutamate synthase (N-acetyl-L-asparagine)
- long-chain-fatty-acid-CoA ligase (physeteric acid)
Catalysed by NAGS, SLC27A2, ACSL4, ACSL3 and 5 moremitochondrial matrix, cytosolOne of 8 routes
- N-acetylglutamate synthase (N-acetyl-L-asparagine)
- Fatty Acid Beta Oxidation (C12:1->C10:1), Mitochondrial
Catalysed by NAGS, ACADM, ECHS1, ACAA2 and 1 moremitochondrial matrix
- transport of asparagine and glycine (cytosol to extracellular)
- tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
Catalysed by GLYATL2extracellular space, cytosol
- transport of asparagine and glycine (cytosol to extracellular)
- eicosanoyl-CoA + glycine = N-eicosanoylglycinate + CoA + H(+)
Catalysed by BAATextracellular space, cytosol
- transport of asparagine and glycine (cytosol to extracellular)
- docosanoyl-CoA + glycine = N-docosanoylglycine + CoA + H(+)
Catalysed by BAATextracellular space, cytosol
- transport of asparagine and glycine (cytosol to extracellular)
- hexacosanoyl-CoA + glycine = N-hexacosanoylglycine + CoA + H(+)
Catalysed by BAATextracellular space, cytosol
- transport of asparagine and glutamine (cytosol to extracellular)
- an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
Catalysed by SLC7A5, GLYATL1B, GLYATL1extracellular space, cytosol
- N-acetylglutamate synthase (N-acetyl-L-asparagine)
- long-chain-fatty-acid-CoA ligase (7-palmitoleic acid)
Catalysed by NAGS, SLC27A2, ACSL4, ACSL3 and 5 moremitochondrial matrix, cytosolOne of 8 routes
- N-acetylglutamate synthase (N-acetyl-L-asparagine)
- long-chain-fatty-acid-CoA ligase (tricosanoic acid)
Catalysed by NAGS, SLC27A2, ACSL4, ACSL3 and 5 moremitochondrial matrix, cytosolOne of 4 routes
Three steps
- transport of asparagine and tyrosine (cytosol to extracellular)
- L-tyrosine:2-oxoglutarate aminotransferase
- (2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoate + NAD(+) = 3-(4-hydroxyphenyl)pyruvate + NADH + H(+)
Catalysed by SLC7A5, GOT2, GOT1, TAT and 1 moreextracellular space, cytosol