Compound

prostaglandin H3

A prostaglandin carboxylic acid anion that is the conjugate base of prostaglandin H3, obtained by deprotonation of the carboxy group; major species at pH 7.3.

Definition from ChEBI (CHEBI:133134), read 2026-09-23. CC BY 4.0.

CHEBI:133134ChEBI

Open in the graph

Structure

2D depiction · 3D model shown

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A generated conformer of prostaglandin H3 — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, anion
Formula: C20H29O5
Mass: 349.447 g/mol
Charge: -1
InChIKey: PVTQTOGPOPGQGE-SAMSIYEGSA-M
SMILES: CC/C=CC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=CCCCC(=O)[O-])[C@@H]2C[C@H]1OO2
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

1 entity

1 entities reached.

0 reported hops1 assembled from the scaffold

PTGS2ProteinUNIPROT:P35354substrate ofInferred only56 paths56 endpoints

What the reference databases state

Statements

1 statement

1 statement · 1 reference database · Subject: prostaglandin H3 · Sources: Rhea

Order

prostaglandin H3 is a substrate of PTGS2ProteinRhea RHEA:50448Inferred only

Reactions

3 reactions

prostaglandin G3+AH2prostaglandin H3+A+water
Catalysed by PTGS2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:50448CC BY 4.0Reference data
prostaglandin H3prostaglandin E3
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:50452CC BY 4.0Reference data
prostaglandin H3CHEBI:132149
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:50456CC BY 4.0Reference data

Other names

2 names

Resolves to: prostaglandin H3

Also called: (5Z,9S,11R,13E,15S,17Z)-15-hydroxy-9,11-epidioxyprosta-5,13,17-trienoate
Systematic name: (5Z)-7-{(1R,4S,5R,6R)-6-[(1E,3S,,5Z)-3-hydroxyocta-1,5-dien-1-yl]-2,3-dioxabicyclo[2.2.1]heptan-5-yl}hept-5-enoate