Compound
biotin
A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
Studied for
3 endpoints · 3 findings · 2 papers · 2 null
- Expanded Disability Status Scale (EDSS)lowersEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.
- Adverse event occurrence (oral or enteral supplement)no detected effectEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.
- Serious adverse event incidenceno detected effectEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.
Structure
Loading the model…
- Class
- Organic compound, anion
- Formula
- C10H15N2O3S
- Mass
- 243.308 g/mol
- Charge
- -1
- InChIKey
- YBJHBAHKTGYVGT-ZKWXMUAHSA-M
- SMILES
- [H][C@]12CS[C@@H](CCCCC(=O)[O-])[C@@]1([H])NC(=O)N2
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What the evidence says
How to read these marks3 findings · 3 endpoints · 2 papers · 2 null · by evidence strength
What moved
1 finding
Decreases expanded Disability Status Scale (EDSS)
ModerateEvidence strength: moderate. Human evidence with one recorded weakness, or capped at moderate by its design or by unread numbers.Finding“At month 12, the mean (±standard deviation (SD)) EDSS decreased from baseline in the MD1003 arm (−0.03 ± 0.50) but increased at the expected rate in the placebo arm (+0.13 ± 0.33, p = 0.01; Figure 3).”
Quoted verbatim from MD1003 (high-dose biotin) for the treatment of progressive multiple sclerosis: A randomised, double-blind, placebo-controlled study.. - Study
- RCT
- Participants
- 154
- Duration
- 12 months
- Dose
- 100 mg biotin orally three times daily (300 mg/day)
- Population
- Adults aged 18-75 with primary or secondary progressive multiple sclerosis, baseline EDSS 4.5-7 and disease worsening in the previous 2 years; month 12 of the double-blind phase; all patients on stable concomitant therapy allowed
MD1003 (high-dose biotin) for the treatment of progressive multiple sclerosis: A randomised, double-blind, placebo-controlled study.2016PMID:27589059Industry fundedPermalink
What did not
2 findings
No detected effect on adverse event occurrence (oral or enteral supplement)
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“Synthesized data on incidence of any AEs (RR 0.98; 95% CI 0.92-1.04; 3 trials; I2 = 0%) [high COE] and any serious AEs (RR 0.98; 95% CI 0.77-1.24; 3 trials; 889 participants; I2 = 0%) [moderate COE] were not significantly different between HDB and placebo groups.”
Quoted verbatim from High-dose biotin for multiple sclerosis: A systematic review and meta-analyses of randomized controlled trials.. - Study
- meta-analysis
- Dose
- high-dose biotin at least 300 mg/day for at least three months
- Population
- Adults with multiple sclerosis (mostly progressive); three pooled randomized trials of oral high-dose biotin (at least 300 mg/day) as adjunctive treatment versus placebo
Effect 0.98 risk ratio, 95% CI 0.92 to 1.04
High-dose biotin for multiple sclerosis: A systematic review and meta-analyses of randomized controlled trials.2021PMID:34332461Permalink
No detected effect on serious adverse event incidence
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.FindingNull result“Synthesized data on incidence of any AEs (RR 0.98; 95% CI 0.92-1.04; 3 trials; I2 = 0%) [high COE] and any serious AEs (RR 0.98; 95% CI 0.77-1.24; 3 trials; 889 participants; I2 = 0%) [moderate COE] were not significantly different between HDB and placebo groups.”
Quoted verbatim from High-dose biotin for multiple sclerosis: A systematic review and meta-analyses of randomized controlled trials.. - Study
- meta-analysis
- Participants
- 889
- Dose
- high-dose biotin at least 300 mg/day for at least three months
- Population
- Adults with multiple sclerosis (mostly progressive); three pooled randomized trials of oral high-dose biotin (at least 300 mg/day) as adjunctive treatment versus placebo
Effect 0.98 risk ratio, 95% CI 0.77 to 1.24
High-dose biotin for multiple sclerosis: A systematic review and meta-analyses of randomized controlled trials.2021PMID:34332461Permalink
What it touches on the way
Mechanistic reach
4 entities
4 entities reached.
0 reported hops4 assembled from the scaffold
What the reference databases state
Regulatory determinations
LiverTox likelihood score ELiverTox
LiverTox Likelihood Score E — despite extensive use, no evidence that the agent has caused liver injury. Chapter: "Vitamin B". Source: LiverTox Master List (NBK571102).
The document·Public Domain (NLM/NIH)·Transcribed, not assessed
Statements
18 statements
18 statements · 3 reference databases · Subject: biotin · Sources: Human-GEM, Rhea, UniProt
- ACACA requires the cofactor biotinProteinUniProt Q13085Inferred only
- ACACB requires the cofactor biotinProteinUniProt O00763Inferred only
- MCCC1 requires the cofactor biotinProteinUniProt Q96RQ3Inferred only
- PC requires the cofactor biotinProteinUniProt P11498Inferred only
- PCCA requires the cofactor biotinProteinUniProt P05165Inferred only
- biotin is a substrate of BTDProteinRhea RHEA:77171Inferred only
- biotin is a substrate of HLCSProteinHuman-GEM MAR07668Inferred only
- biotin is a substrate of HLCSProteinRhea RHEA:11204Inferred only
- biotin is a substrate of HLCSProteinRhea RHEA:11756Inferred only
- biotin is a substrate of HLCSProteinRhea RHEA:23668Inferred only
- biotin is a substrate of HLCSProteinRhea RHEA:24376Inferred only
- biotin is a substrate of HLCSProteinHuman-GEM MAR00086Inferred only
Show the remaining 6
- biotin is transported by SLC16A1ProteinHuman-GEM MAR00093Inferred only
- biotin is transported by SLC16A1ProteinHuman-GEM MAR07666Inferred only
- biotin is transported by SLC5A6ProteinHuman-GEM MAR09609Inferred only
- biotin is transported by SLC5A6ProteinRhea RHEA:73375Inferred only
- biotin is transported by SLC5A6ProteinHuman-GEM MAR00094Inferred only
- biotin is transported by SLC5A6ProteinHuman-GEM MAR07667Inferred only
Reactions
31 reactions
MAM00209m+biotin+CHEBI:1146900+MAM01600m+ferroheme c di-L-cysteine(2-) residue+FADH2+(S)-carnitine+NADH(2-)+NADPH(4-)+riboflavin+5,6,7,8-tetrahydrobiopterin+5,6,7,8-tetrahydrofolic acid+ubiquinol+0.1MAM03139c+0.1MAM03140c+0.1MAM03143cMAM01602c
Reaction pageLeft to rightBalance undeterminablemitochondrial matrix, cytosol
Human-GEM MAR00022CC BY 4.0Reference data
ATP+biotin+protonMAM01402m+diphosphate(3-)
Catalysed by HLCS
Reaction pageLeft to rightBalancedEC 6.3.4.15mitochondrial matrix
Human-GEM MAR00086CC BY 4.0Reference data
biocytin+waterbiotin+CHEBI:18019
Catalysed by BTD
Reaction pageLeft to rightBalancedEC 3.5.1.12mitochondrial matrix
Human-GEM MAR00091CC BY 4.0Reference data
Transported by SLC16A1
Reaction pageReversibleBalancedEC 3.5.1.12cytosol, mitochondrial matrix
Human-GEM MAR00093CC BY 4.0Reference data
ATP+biotin+water+sodium(1+)ADP+biotin+proton+sodium(1+)+phosphate(3-)
Transported by SLC5A6
Reaction pageLeft to rightBalancedcytosol, extracellular space
Human-GEM MAR00094CC BY 4.0Reference data
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR00095CC BY 4.0Reference data
Reaction pageLeft to rightBalancedcytosol, extracellular space
Human-GEM MAR06870CC BY 4.0Reference data
biocytin+waterbiotin+CHEBI:18019
Catalysed by BTD
Reaction pageLeft to rightBalancedEC 3.5.1.12cytosol
Human-GEM MAR07661CC BY 4.0Reference data
biocytin+waterbiotin+CHEBI:18019
Catalysed by BTD
Reaction pageLeft to rightBalancedEC 3.5.1.12nucleus
Human-GEM MAR07662CC BY 4.0Reference data
biocytin+waterbiotin+CHEBI:18019
Catalysed by BTD
Reaction pageLeft to rightBalancedEC 3.5.1.12extracellular space
Human-GEM MAR07663CC BY 4.0Reference data
Reaction pageReversibleBalancedcytosol, nucleus
Human-GEM MAR07665CC BY 4.0Reference data
Transported by SLC16A1
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR07666CC BY 4.0Reference data
On the label
Labelled products
9,547 products
Source: NIH DSLD · Ingredient: biotin · 9,547 products · Declared amount per serving: 1–10,000 mcg (957 products) · Showing 1,000 of 9,547
967 labels state an amount33 do not
- 1st PhormM-Factor Hero300 mcgper 3 Capsule(s)DSLD:12881
- 21st CenturyDiabetic Support Formula30 mcgper 3 Tablet(s)DSLD:11189
- 21st CenturyMaximum Strength Biotin 800 mcg800 mcgper 1 Tablet(s)DSLD:11051
- 21st CenturyOne Daily Active40 mcgper 1 Tablet(s)DSLD:11548
- 21st CenturyOne Daily Adults 50+30 mcgper 1 Tablet(s)DSLD:11549
- 21st CenturyOne Daily Cholesterol Health With Policosanol50 mcgper 1 Tablet(s)DSLD:11550
- 21st CenturyOne Daily Energy300 mcgper 1 Tablet(s)DSLD:11552
- 21st CenturyOne Daily Maximum30 mcgper 1 Tablet(s)DSLD:11558
- 21st CenturyOne Daily Men's Health30 mcgper 1 Tablet(s)DSLD:11559
- 21st CenturyOne Daily Women's30 mcgper 1 Tablet(s)DSLD:11561
- 21st CenturyOne Daily Women's 50+30 mcgper 1 Tablet(s)DSLD:11497
- 21st CenturyStress B45 mcgper 1 Tablet(s)DSLD:11599
Show the remaining 9,535
- 21st Century Zoo FriendsComplete20 mcgper 1 Tablet(s)DSLD:11637
- 365 Everyday ValueAdult Multi for MenD-Biotin · Biotin (Form: as D-Biotin)150 mcgper 1 Tablet(s)DSLD:12017
- 365 Everyday ValueAdult Multi with IronD-Biotin · Biotin (Form: as D-Biotin)30 mcgper 1 Tablet(s)DSLD:184071
- 365 Everyday ValueKid's Gummy Multi-Vitamin66 mcgper 1 Gummy(ies)DSLD:184073
- AB American BiologicsSuper B Caps1,000 mcgper 2 Capsule(s)DSLD:20287
- AB American BiologicsSuper B Caps1,000 mcgper 2 Capsule(s)DSLD:203547
- AB American BiologicsUltra AB Multi Complex75 mcgper 1 Capsule(s)DSLD:203588
- AdvoCareCore Nutrition System300 mcgper 1 4-Packet Strip(s)DSLD:177397
- AdvoCareHerbal Cleanse P.M.200 mcgper 2 Caplet(s)DSLD:177797
- AdvoCareMNS 3300 mcgper 2 Packet(s)DSLD:177961
- AdvoCareMNS E300 mcgper 1 Packet(s)DSLD:177964
- AdvoCareSlim Apple Pear600 mcgper 4.8 Gram(s)DSLD:178397
- AdvoCareSlim Lemonade600 mcgper 5 Gram(s)DSLD:178406
- Aidan ProductsIvc-Max200 mcgper 1 Capsule(s)DSLD:179939
- AkesoMigreLief+MD-Biotin15 mgper 2 Caplet(s)DSLD:183028
- Alani NuHair Skin & Nails5,000 mcgper 2 Veggie Capsule(s)DSLD:202313
- AlconI-Caps MV30 mcgper 2 Tablet(s)DSLD:17676
- AlconI-Caps MV15 mcgper 2 Tablet(s)DSLD:18979
- Allergy Research GroupEPD Basic Multivitamin100 mcgper 2 Capsule(s)DSLD:183168
- Allergy Research GroupMetabolic Co-Factor500 mcgper 6 Capsule(s)DSLD:184081
- AltrumNutritional Drink Mix Chocolate100 mcgper 28 Gram(s)DSLD:204117
- AltrumNutritional Drink Mix Vanilla Flavor100 mcgper 26 Gram(s)DSLD:204134
- AltrumUltra Multi with Iron300 mcgper 6 Tablet(s)DSLD:204059
- Amazon ElementsAdult One DailyD-Biotin · Biotin (Form: as D-Biotin (Form: from cultured Yeast))150 mcgper 1 Tablet(s)DSLD:203783
- Amazon ElementsBiotin 5000 mcg5,000 mcgper 1 Capsule(s)DSLD:203789
- Amazon ElementsMen's 40+ One DailyD-Biotin · Biotin (Form: as D-Biotin (Form: from cultured Yeast))200 mcgper 1 Tablet(s)DSLD:203827
- American HealthNutri-MegaD-Biotin · Biotin (Form: as D-Biotin)50 mcgper 2 Softgel(s)DSLD:16693
- American HealthNutri-MegaD-Biotin · Biotin (Form: as D-Biotin)50 mcgper 2 Softgel(s)DSLD:16695
- AnimalAnimal Pak300 mcgper 1 Packet(s)DSLD:174541
- AnutraAnutra Grain3 mcgper 2.5 TbspDSLD:12805
- AnutraOmega-3s Antioxidants1 mcgper 2 Capsule(s)DSLD:12796
- Bariatric AdvantageMulti Formula With Antioxidants600 mcgper 6 Capsule(s)DSLD:11997
- Bausch & LombOcuvite Eye+Multi30 mcgper 2 Tablet(s)DSLD:17096
- BayerFlintstones Complete20 mcgper 0.5 Tablet(s)DSLD:19003
- BayerFlintstones Complete20 mcgper 0.5 Tablet(s)DSLD:19141
- BayerFlintstones Gummies Complete75 mcgper 1 Gummy(ies)DSLD:12227
- BayerFlintstones Gummies Complete37.5 mcgper 1 Gummy(ies)DSLD:19354
- BayerFlintstones Sour Gummies Complete37.5 mcgper 1 Gummy(ies)DSLD:12000
- Bayer One A DayEnergy300 mcgper 1 Tablet(s)DSLD:178021
- Bayer One A DayMen's 50+ Healthy Advantage30 mcgper 1 Tablet(s)DSLD:178055
- Bayer One A DayMen's 50+ Healthy Advantage30 mcgper 1 Tablet(s)DSLD:19342
- Bayer One A DayMen's Health Formula30 mcgper 1 Tablet(s)DSLD:17190
- Bayer One A DayMen's Health Formula30 mcgper 1 Tablet(s)DSLD:17213
- Bayer One A DayMen's Health Formula75 mcgper 1 Tablet(s)DSLD:178058
- Bayer One A DayMen's VitaCraves Gummies600 mcgper 2 Gummy(ies)DSLD:17230
- Bayer One A DayTeen Advantage for Her Complete Multivitamin300 mcgper 1 Caplet(s)DSLD:17231
- Bayer One A DayTeen Advantage for Him Complete Multivitamin300 mcgper 1 Caplet(s)DSLD:17214
- Bayer One A DayVitaCraves Gummies150 mcgper 2 Gummy(ies)DSLD:17176
- Bayer One A DayVitaCraves Gummies150 mcgper 2 Gummy(ies)DSLD:17177
- Bayer One A DayVitaCraves Gummies +Immunity Support150 mcgper 2 Gummy(ies)DSLD:17178
- Bayer One A DayVitaCraves Gummies +Omega-3 DHA Fruit Punch Flavored150 mcgper 2 Gummy(ies)DSLD:17180
- Bayer One A DayVitaCraves Men's Multi Gummies600 mcgper 2 Gummie(s)DSLD:178126
- Bayer One A DayWomen's 2O Mixed Berry Flavor30 mcgper 1 Packet(s)DSLD:12230
- Bayer One A DayWomen's 50+ Healthy Advantage30 mcgper 1 Tablet(s)DSLD:178201
- Bayer One A DayWomen's Formula30 mcgper 1 Tablet(s)DSLD:17183
- Bayer One A DayWomen's Formula30 mcgper 1 Tablet(s)DSLD:17222
- Bayer One A DayWomen's Formula300 mcgper 1 Tablet(s)DSLD:178212
- Bayer One A DayWomen's Prenatal 1300 mcgper 1 Softgel(s)DSLD:178392
- Bayer One A DayWomen's Prenatal with DHA300 mcgper 1 Tablet(s)DSLD:178394
- Bayer One A Day AdultVitaCraves Energy Support Multi Gummies Cola Lime Flavor300 mcgper 4 Gummie(s)DSLD:178113
- Bayer One A Day AdultVitaCraves Healthy Metabolism Support Multi Gummies300 mcgper 2 Gummie(s)DSLD:178116
- Bayer One A Day AdultVitaCraves Multi + Omega-3 DHA Gummies Fruit Punch Flavor150 mcgper 2 Gummie(s)DSLD:178148
- Bayer One A Day KidsBatman Complete Multivitamin Gummies75 mcgper 1 Gummy(ies)DSLD:178024
- Bayer One A Day KidsHello Kitty Complete Multivitamin Gummies75 mcgper 1 Gummy(ies)DSLD:178052
- Beyond HumanBlood Sugar Support300 mcgper 1 Capsule(s)DSLD:181927
- Bio NutritionBiotin 10,000 mcg10,000 mcgper 1 Tablet(s)DSLD:200629
- Bio NutritionHealthy Hair with Biotin 10,000 Plus10 mgper 1 Vegetarian Capsule(s)DSLD:200570
- Bio NutritionWomen's Wellness300 mcgper 1 Tablet(s)DSLD:200802
- BiochemB Beet Energizer Watermelon FlavorD-Biotin · Biotin (Form: as D-Biotin)54 mcgper 3.3 Gram(s)DSLD:183858
- BiochemBC B-Complex Enhancerorganic Sesbania extract · Biotin (Form: from organic Sesbania extract PlantPart: leaf)6 mcgper 2.3 Gram(s)DSLD:183835
- BiochemH Hydro Recovery Coconut FlavorD-Biotin · Biotin (Form: as D-Biotin)54 mcgper 4.9 Gram(s)DSLD:183896
- BioChem SportsTri Protein Plus Powder ChocolateD-Biotin · Biotin (Form: as D-Biotin)140 mcgper 45 Gram(s)DSLD:13297
- BioChem SportsTri Protein Plus Powder VanillaD-Biotin · Biotin (Form: as D-Biotin)140 mcgper 45 Gram(s)DSLD:13287
- BioSource LabsWhole Food MultivitaminD-Biotin · Biotin (Form: as D-Biotin) Note: 1 mg1,000 mcgper 3 Tablet(s)DSLD:174998
- BluebonnetMaxi One75 mcgper 1 Caplet(s)DSLD:177475
- BluebonnetMaxi Two100 mcgper 2 Caplet(s)DSLD:177519
- BluebonnetMaxi Two100 mcgper 2 Caplet(s)DSLD:177530
- BluebonnetMaxi Two Iron-Free100 mcgper 2 Caplet(s)DSLD:177608
- BluebonnetMaxi Two Iron-Free100 mcgper 2 Caplet(s)DSLD:177609
- BluebonnetMulti Vita Softgels200 mcgper 2 Softgel(s)DSLD:177618
- BluebonnetMulti Vita Softgels200 mcgper 2 Softgel(s)DSLD:177617
- BluebonnetSuper Vita-CoQ10 Formula300 mcgper 3 Caplet(s)DSLD:177532
- BluebonnetSuper Vita-CoQ10 Formula300 mcgper 3 Caplet(s)DSLD:177533
- BluebonnetSuper Vita-CoQ10 Formula300 mcgper 3 Caplet(s)DSLD:177535
- BluebonnetSuper Vita-CoQ10 Formula300 mcgper 3 Caplet(s)DSLD:177536
- BluebonnetUltimate Hair & Nail Formula1,000 mcgper 3 Capsule(s)DSLD:179115
- BluebonnetUltimate Hair & Nail Formula1,000 mcgper 3 Capsule(s)DSLD:179124
- BluebonnetVeggie Choice300 mcgper 3 Caplet(s)DSLD:177732
- Bluebonnet Early Promise PrenatalGentle Multiple300 mcgper 2 Caplet(s)DSLD:177853
- Bluebonnet Rainforest AnimalzMultiple Grape Flavor50 mcgper 2 Animal Shaped Chewable(s)DSLD:204597
- Bluebonnet Rainforest Animalz Multiple Cherry Flavor50 mcgper 2 Animal Shaped Chewable(s)DSLD:204695
- Bluebonnet Super EarthBrewer's Yeast PowderBiotin Note: Vitamin and mineral content is based on an average; amounts may vary.9 mcgper 30 Gram(s)DSLD:179302
- Bluebonnet Super EarthLiquid Multinutrient Formula Natural Tropical Fruit FlavorD-Biotin · Biotin (Form: as D-Biotin)10 mcgper 2 TbspDSLD:177417
- Bluebonnet Super EarthMultiNutrient100 mcgper 3 Caplet(s)DSLD:177507
- Bluebonnet Super EarthMultiNutrient100 mcgper 6 Mini-Caplet(s)DSLD:177442
- Bluebonnet Super EarthMultiNutrient100 mcgper 6 Mini-Caplet(s)DSLD:177460
- Bluebonnet Super EarthMultiNutrient100 mcgper 6 Mini-Caplet(s)DSLD:177464
- Bluebonnet Super EarthMultiNutrient100 mcgper 6 Mini-Caplet(s)DSLD:177462
- Bluebonnet Super EarthMultiNutrient100 mcgper 3 Caplet(s)DSLD:177508
- Bluebonnet Super EarthMultiNutrient100 mcgper 3 Caplet(s)DSLD:177511
- Bluebonnet Super EarthMultiNutrient100 mcgper 3 Caplet(s)DSLD:177516
- Bluebonnet Super EarthMultiNutrient100 mcgper 3 Caplet(s)DSLD:177517
- Bluebonnet Super EarthMultiNutrient Iron Free100 mcgper 3 Caplet(s)DSLD:177494
- Bluebonnet Super EarthSingle 1 Daily100 mcgper 1 Caplet(s)DSLD:177572
- Bluebonnet Super EarthSingle 1 Daily100 mcgper 1 Caplet(s)DSLD:177574
- Bluebonnet Super EarthSingle 1 Daily100 mcgper 1 Caplet(s)DSLD:177576
- Bluebonnet Super EarthSingle 1 Daily Iron Free100 mcgper 1 Caplet(s)DSLD:177559
- Bluebonnet Super EarthSingle 1 Daily Iron Free100 mcgper 1 Caplet(s)DSLD:177568
- Bluebonnet Super EarthSingle 1 Daily Iron Free100 mcgper 1 Caplet(s)DSLD:177571
- Bluebonnet Super Earth Rainforest AnimalzWhole Food Based Multiple160 mcgper 2 Animal Shaped Chewable(s)DSLD:12923
- Bodybuilding.com Foundation SeriesWomen's Multivitamin300 mcgper 2 Tablet(s)DSLD:193269
- BodyBuilding.com Foundation SeriesMultiVitamin300 mcgper 2 Capsule(s)DSLD:175062
- Bodybuilding.com Platinum SeriesMulticore300 mcgper 1 Packet(s)DSLD:175353
- BodyTechUltimate Man EliteD-Biotin300 mcgper 2 Tablet(s)DSLD:204545
- Botanic ChoiceBiotin 5,000 mcg10,000 mcgper 1 Vege Capsule(s)DSLD:199860
- Botanic ChoiceSTART! Multi-Vitamin + Digestion30 mcgper 2 Vege Capsule(s)DSLD:200063
- Botanic ChoiceStart! Multi-Vitamin + Energy30 mcgper 2 Vege Capsule(s)DSLD:200061
- Botanic ChoiceSTART! Multi-Vitamin + Heart30 mcgper 1 Vege Capsule(s)DSLD:200048
- Botanic ChoiceSTART! Multi-Vitamin + Joints30 mcgper 1 Vege Capsule(s)DSLD:199933
- Botanic ChoiceSTART! Multi-Vitamin + Vision30 mcgper 1 Vege Capsule(s)DSLD:200041
- Botanic ChoiceSTART! Multi-Vitamin + Weight30 mcgper 2 Vege Capsule(s)DSLD:199929
- Botanic ChoiceSTART! Multi-Vitamin for Men30 mcgper 1 Vege Capsule(s)DSLD:200056
- Botanic ChoiceSTART! Multi-Vitamin for Women30 mcgper 1 Vege Capsule(s)DSLD:200058
- California Academy of HealthPower Multi-V Vegi Capsules50 mcgper 2 Capsule(s)DSLD:193343
- CarlsonSuper 1 Daily300 mcgper 1 Tablet(s)DSLD:19660
- CelsiusCelsius Heat Apple Jack'd300 mcgper 16 fl. Oz.DSLD:202716
- CelsiusCelsius Heat Tangerine Grapefruit300 mcgper 16 fl. Oz.DSLD:202804
- CelsiusCelsius Heat Watermelon Berry300 mcgper 12 fl. Oz.DSLD:202801
- CelsiusCelsius Pineapple Coconut300 mcgper 12 fl. Oz.DSLD:202799
- CelsiusCelsius Sparkling Cola300 mcgper 12 fl. Oz.DSLD:17935
- CelsiusCelsius Strawberries & Cream300 mcgper 12 fl. Oz.DSLD:202800
- CentrumCentrum Adults30 mcgper 1 Tablet(s)DSLD:200827
- CentrumCentrum Adults30 mcgper 1 Tablet(s)DSLD:204642
- CentrumCentrum Adults Under 5030 mcgper 1 Tablet(s)DSLD:17139
- CentrumCentrum Adults Under 5030 mcgper 1 Tablet(s)DSLD:19008
- CentrumCentrum Adults Under 5030 mcgper 1 Tablet(s)DSLD:19090
- CentrumCentrum Flavor Burst Kids Grape & Blue Raspberry75 mcgper 2 Chew(s)DSLD:174643
- CentrumCentrum Flavor Burst Mixed Fruit150 mcgper 4 Chew(s)DSLD:19163
- CentrumCentrum Flavor Burst Mixed Fruit150 mcgper 4 Chew(s)DSLD:19174
- CentrumCentrum Flavor Burst Mixed Fruit150 mcgper 4 Chew(s)DSLD:200984
- CentrumCentrum Flavor Burst Wild Grape150 mcgper 4 Chew(s)DSLD:19177
- CentrumCentrum Flavor Burst Wild Grape150 mcgper 4 Chew(s)DSLD:20211
- CentrumCentrum Flavor Burst Wild Grape Adult Chews150 mcgper 4 Chew(s)DSLD:19175
- CentrumCentrum Liquid300 mcgper 1 TbspDSLD:19178
- CentrumCentrum Liquid Adults Orange Tangerine300 mcgper 1 TbspDSLD:200816
- CentrumCentrum Men40 mcgper 1 Tablet(s)DSLD:204788
- CentrumCentrum Men Under 5040 mcgper 1 Tablet(s)DSLD:17144
- CentrumCentrum Men Under 5040 mcgper 1 Tablet(s)DSLD:18988
- CentrumCentrum Multi + Probiotics Adults 50+45 mcgper 1 Tablet(s)DSLD:200928
- CentrumCentrum MultiGummies Adults 50+ Assorted Natural Fruit Flavors75 mcgper 2 Gummie(s)DSLD:204875
- CentrumCentrum MultiGummies Adults Assorted Natural Fruit Flavors30 mcgper 2 Gummie(s)DSLD:204660
- CentrumCentrum MultiGummies Men 50+ Assorted Natural Fruit Flavors30 mcgper 2 Gummie(s)DSLD:204874
- CentrumCentrum MultiGummies Men Assorted Natural Fruit Flavors30 mcgper 2 Gummie(s)DSLD:204872
- CentrumCentrum MultiGummies Multi + Antioxidants30 mcgper 2 Gummie(s)DSLD:204687
- CentrumCentrum MultiGummies Multi + Omega-375 mcgper 2 Gummie(s)DSLD:200971
- CentrumCentrum Silver Adults 50+30 mcgper 1 Tablet(s)DSLD:18940
- CentrumCentrum Silver Adults 50+30 mcgper 1 Tablet(s)DSLD:18997
- CentrumCentrum Silver Adults 50+30 mcgper 1 Tablet(s)DSLD:19001
- CentrumCentrum Silver Adults 50+30 mcgper 1 Tablet(s)DSLD:204705
- CentrumCentrum Silver Chewables Adults 50+ Citrus Berry45 mcgper 1 Tablet(s)DSLD:200873
- CentrumCentrum Silver Chewables Citrus Berry45 mcgper 1 Tablet(s)DSLD:18924
- CentrumCentrum Silver Men 50+30 mcgper 1 Tablet(s)DSLD:19013
- CentrumCentrum Silver Men 50+30 mcgper 1 Tablet(s)DSLD:200883
- CentrumCentrum Silver Women 50+30 mcgper 1 Tablet(s)DSLD:18918
- CentrumCentrum Silver Women 50+30 mcgper 1 Tablet(s)DSLD:18935
- CentrumCentrum Silver Women 50+30 mcgper 1 Tablet(s)DSLD:204780
- CentrumCentrum Silver Women 50+30 mcgper 1 Tablet(s)DSLD:204787
- CentrumCentrum Specialist Heart15 mcgper 1 Tablet(s)DSLD:19143
- CentrumCentrum Specialist Prenatal30 mcgper 1 Tablet(s)DSLD:19028
- CentrumCentrum Specialist Vision30 mcgper 2 Tablet(s)DSLD:19157
- CentrumCentrum VitaMints60 mcgper 2 Minty Chewable(s)DSLD:200851
- CentrumCentrum Women Under 5040 mcgper 1 Tablet(s)DSLD:17148
- CentrumCentrum Women Under 5040 mcgper 1 Tablet(s)DSLD:18913
- CentrumCentrum Women Under 5040 mcgper 1 Tablet(s)DSLD:18934
- ChampBevMuscle Milk Banana Creme Shake65 mcgper 11 fl. Oz.DSLD:14419
- ChampBevMuscle Milk Banana Creme Shake99 mcgper 17 fl. Oz.DSLD:14447
- ChampBevMuscle Milk Chocolate Milk Shake65 mcgper 11 fl. Oz.DSLD:14479
- ChampBevMuscle Milk Chocolate Milk Shake99 mcgper 17 fl. Oz.DSLD:14485
- ChampBevMuscle Milk Cookies 'N' Creme Shake65 mcgper 11 fl. Oz.DSLD:14491
- ChampBevMuscle Milk Vanilla Creme Shake65 mcgper 11 fl. Oz.DSLD:14529
- Chiro-ZymeVSCLR10 mcgper 2 Capsule(s)DSLD:176681
- Chiro-ZymeVSCLR10 mcgper 2 Capsule(s)DSLD:176684
- CHK NutritionChewable Kids' MultiD-Biotin · Biotin (Form: as D-Biotin)50 mcgper 2 Tablet(s)DSLD:174166
- CHK NutritionUltimate B ComplexD-Biotin · Biotin (Form: as D-Biotin)150 mcgper 2 Tablet(s)DSLD:174259
- Colossal LabsMonster Muscle Up-Gainer Cookies & Cream75 mcgper 391 Gram(s)DSLD:177400
- ComplexinComplexin Super Supplement75 mcgper 3 Capsule(s)DSLD:180964
- Convida. Powered by Vibrant HealthBuen Dia Natural French Vanilla Flavor27 mcgper 22.6 Gram(s)DSLD:182888
- Core NutritionalsMRP Blueberry Crumb Cake75 mcgper 68 Gram(s)DSLD:183358
- Country FarmsLiving Foods Multi-Vitamin50 mcgper 1 Vegetarian Tablet(s)DSLD:181010
- Country FarmsSuper Greens Protein Shake Tahitian Vanilla Flavor105 mcgper 1 Gram(s)DSLD:181025
- Country LifeBeet & B Energizer Powder Watermelon FlavorD-Biotin · Biotin (Form: as D-Biotin)54 mcgper 3.3 Gram(s)DSLD:179776
- Country LifeBeyond Food Iron FreeD-Biotin · Biotin (Form: as D-Biotin)200 mcgper 4 Capsule(s)DSLD:183938
- Country LifeCoenzyme B-Complex Powder CoconutD-Biotin · Biotin (Form: as D-Biotin)200 mcgper 1.8 Gram(s)DSLD:179887
- Country LifeDaily Multi-SorbD-Biotin · Biotin (Form: as D-Biotin)100 mcgper 2 Softgel(s)DSLD:13808
- Country LifeDaily Total One With Maxi-Sorb Delivery System With Iron!D-Biotin · Biotin (Form: as D-Biotin)100 mcgper 1 Capsule(s)DSLD:13916
- Country LifeDolphin Pals Multivitamin & MineralD-Biotin · Biotin (Form: as D-Biotin)44 mcgper 3 Gummy(ies)DSLD:13402
- Country LifeHi-Potency Maxi B-Caps With Taurine And Coenzymated B VitaminsD-Biotin · Biotin (Form: as D-Biotin)300 mcgper 1 Capsule(s)DSLD:14179
- Country LifeKids Liquid Dolphin Pals Multivitamin & Mineral Complex Berry SplashD-Biotin · Biotin (Form: as d-Biotin)45 mcgper 1 tspDSLD:13430
- Country LifeMaxi Baby CareD-Biotin · Biotin (Form: as D-Biotin)30 mcgper 1 tspDSLD:13421
- Country LifeMaxi Baby Care Liquid Natural Raspberry FlavorD-Biotin · Biotin (Form: as D-Biotin)30 mcgper 1 tspDSLD:1603
- Country LifeMulti-100D-Biotin · Biotin (Form: as D-Biotin)100 mcgper 1 Tablet(s)DSLD:13945
- Country LifeSeniority MultivitaminD-Biotin · Biotin (Form: as D-Biotin)300 mcgper 2 Capsule(s)DSLD:13934
- Country LifeStress "M"D-Biotin · Biotin (Form: as D-Biotin)300 mcgper 2 Tablet(s)DSLD:14178
- Country LifeTall Tree Natural Orange & Pineapple FlavorD-Biotin · Biotin (Form: as D-Biotin)50 mcgper 1 Wafer(s)DSLD:13407
- Country Life Realfood OrganicsFor MenBiotin (Form: from Organic Food Blend)30 mcgper 2 Tablet(s)DSLD:183920
- Country Life Realfood OrganicsYour Daily NutritionD-Biotin · Biotin (Form: as D-Biotin)300 mcgper 1 Tablet(s)DSLD:13971
- CRC The Carter-Reed CompanyRelacore Extra50 mcgper 2 Capsule(s)DSLD:17961
- CVS PharmacyBalanced B-100D-Biotin · Biotin (Form: as D-Biotin)100 mcgper 1 Caplet(s)DSLD:19173
- CVS PharmacyBalanced B-150D-Biotin · Biotin (Form: as D-Biotin)150 mcgper 1 Caplet(s)DSLD:19176
- CVS PharmacyDaily Menopause300 mcgper 1 Tablet(s)DSLD:18193
- CVS PharmacyDaily Multiple For Men 50+30 mcgper 1 Tablet(s)DSLD:12089
- CVS PharmacyDaily Multiple For Women 50+30 mcgper 1 Tablet(s)DSLD:18147
- CVS PharmacyDaily Multiple For Women 50+30 mcgper 1 Tablet(s)DSLD:18156
- CVS PharmacyDaily Multiple USP For MenD-Biotin · Biotin (Form: as D-Biotin)30 mcgper 1 Tablet(s)DSLD:18161
- CVS PharmacyDaily Multiple USP For MenD-Biotin · Biotin (Form: as D-Biotin)30 mcgper 1 Tablet(s)DSLD:18170
- CVS PharmacyDaily Multiple USP For WomenD-Biotin · Biotin (Form: as D-Biotin)30 mcgper 1 Tablet(s)DSLD:18138
- CVS PharmacyDaily Multiple USP For WomenD-Biotin · Biotin (Form: as D-Biotin)30 mcgper 1 Tablet(s)DSLD:18196
- CVS PharmacySpectravite Advanced FormulaD-Biotin · Biotin (Form: as D-Biotin)30 mcgper 1 Tablet(s)DSLD:12012
- CVS PharmacySpectravite Ultra Women's Health SeniorD-Biotin · Biotin (Form: as D-Biotin)30 mcgper 1 Tablet(s)DSLD:18269
- CVS PharmacySuper B Complex With Vitamin C5 mcgper 1 Caplet(s)DSLD:19182
- CVS PharmacySuper B Complex With Vitamin C5 mcgper 1 Caplet(s)DSLD:19181
- CytoSportMuscle Milk Brownie Batter105 mcgper 70 Gram(s)DSLD:14467
- CytoSportMuscle Milk Collegiate Chocolate Milk Shake60 mcgper 11 fl. Oz.DSLD:14534
- CytoSportMuscle Milk Collegiate Vanilla Creme Shake60 mcgper 11 fl. Oz.DSLD:14584
- CytoSportMuscle Milk Light Banana Creme105 mcgper 50 Gram(s)DSLD:14588
- CytoSportMuscle Milk Light Cake Batter105 mcgper 50 Gram(s)DSLD:14597
- CytoSportMuscle Milk Light Chocolate Milk105 mcgper 50 Gram(s)DSLD:14600
- CytoSportMuscle Milk Light Chocolate Milk105 mcgper 50 Gram(s)DSLD:14607
- CytoSportMuscle Milk Light Peanut Butter Chocolate105 mcgper 50 Gram(s)DSLD:14613
- CytoSportMuscle Milk Light Vanilla Creme105 mcgper 50 Gram(s)DSLD:14616
- CytoSportMuscle Milk Orange Cremeamount not statedper 75 Gram(s)DSLD:14498
- CytoSportMuscle Milk Strawberry Bananaamount not statedper 75 Gram(s)DSLD:14522
- DinosaursMultiSaurus Vitamins & Minerals Mixed Berry50 mcgper 1 Tablet(s)DSLD:13509
- DNA MiraclesChewable Multivitamin Mixed Berry150 mcgper 0.5 Tablet(s)DSLD:204161
- DNA Miracles IsotonixMultivitamin33 mcgper 3.3 Gram(s)DSLD:204183
- Doctor GilmoreCocoSkin PlusD-Biotin · Biotin (Form: as D-Biotin Note: USP)5,000 mcgper 1 Vegetarian Liquid Capsule(s)DSLD:182017
- Doctor GilmoreEssentials Complete Multivitamin300 mcgper 1 Tablet(s)DSLD:182051
- Doctor's BestBiotin 5000 mcg5,000 mcgper 1 Veggie Capsule(s)DSLD:203148
- Doctor's BestMulti-Vitamin with Vitashine D3 and Quatrefolic600 mcgper 3 Veggie Capsule(s)DSLD:203287
- Doctor's BestStabilized R-Lipoic Acid 100 mg150 mcgper 1 Veggie Capsule(s)DSLD:203028
- Doctor's BestStabilized R-Lipoic Acid 100 mg150 mcgper 1 Veggie Capsule(s)DSLD:202942
- doTERRAMicroplex VMzGlycoprotein Matrix · Biotin (Form: as Glycoprotein Matrix)300 mcgper 4 Capsule(s)DSLD:202953
- doTERRAVegan Microplex VMzGlycoprotein Matrix · Biotin (Form: as Glycoprotein Matrix)300 mcgper 4 Capsule(s)DSLD:203098
- dotFITActiveMV150 mcgper 1 Tablet(s)DSLD:12980
- Douglas LaboratoriesADDtend60 mcgper 6 Capsule(s)DSLD:10334
- Douglas LaboratoriesBasic Antiox150 mcgper 1 Packet(s)DSLD:10794
- Douglas LaboratoriesBasic Preventive 1 (Plus Iron And Copper)300 mcgper 6 Tablet(s)DSLD:10777
- Douglas LaboratoriesBasic Preventive 2 (Iron And Copper Free)300 mcgper 6 Tablet(s)DSLD:10782
- Douglas LaboratoriesBasic Preventive 3300 mcgper 6 Tablet(s)DSLD:10784
- Douglas LaboratoriesBasic Preventive 5 Plus Extra Vitamin D300 mcgper 6 Tablet(s)DSLD:10673
- Douglas LaboratoriesBasic Preventive 5 Plus Extra Vitamin D300 mcgper 6 Tablet(s)DSLD:10791
- Douglas LaboratoriesBasics Plus With Copper150 mcgper 1 Packet(s)DSLD:10769
- Douglas LaboratoriesEssential-4 Nutrition Pack150 mcgper 1 Packet(s)DSLD:10038
- Douglas LaboratoriesGlucoPack1,400 mcgper 1 Packet(s)DSLD:10869
- Douglas LaboratoriesLDA Formula300 mcgper 9 Vegetarian Capsule(s)DSLD:10489
- Douglas LaboratoriesLongevity Support Pack150 mcgper 1 Pack(s)DSLD:10041
- Douglas LaboratoriesNutri-Immuno Pack With Herbs134 mcgper 10 Capsule(s)DSLD:10048
- Douglas LaboratoriesUltra Cardio Support Pack150 mcgper 1 Packet(s)DSLD:10045
- Douglas LaboratoriesUltra Preventive300 mcgper 8 Tablet(s)DSLD:176643
- Douglas LaboratoriesUltra Preventive Forte-Chel300 mcgper 9 Tablet(s)DSLD:10212
- Douglas LaboratoriesUltra Preventive Forte-Chel (Capsules)300 mcgper 15 Capsule(s)DSLD:10186
- Douglas LaboratoriesUltra Preventive IX300 mcgper 7 Tablet(s)DSLD:10250
- Douglas LaboratoriesUltra Preventive IX300 mcgper 7 Tablet(s)DSLD:10256
- Douglas LaboratoriesUltra Preventive IX With Vitamin K300 mcgper 7 Tablet(s)DSLD:10257
- Douglas LaboratoriesUltra Preventive IX With Vitamin K300 mcgper 7 Tablet(s)DSLD:10259
- Douglas LaboratoriesUltra Preventive N.A.25 mcgper 1 Capsule(s)DSLD:10073
- Douglas LaboratoriesUltra Preventive N.A.25 mcgper 1 Capsule(s)DSLD:10074
- Douglas LaboratoriesUltra Preventive World Formula37.5 mcgper 2 Vegetarian Capsule(s)DSLD:10716
- Douglas LaboratoriesUltra Preventive-Beta With Copper & Iron With Natural Mixed Carotenoids300 mcgper 6 Tablet(s)DSLD:10089
- Douglas LaboratoriesUltra Preventive-Beta With Copper With Natural Mixed Carotenoids300 mcgper 6 Tablet(s)DSLD:10087
- Douglas LaboratoriesUltra Preventive-Beta With Copper With Natural Mixed Carotenoids300 mcgper 6 Tablet(s)DSLD:10088
- Douglas LaboratoriesVita-Big Kids150 mcgper 6 Capsule(s)DSLD:10215
- Douglas LaboratoriesVita-Kids300 mcgper 2 Tablet(s)DSLD:10502
- Dr. Mann PharmaVivioptal Capsulas Vitamina y Minerales50 mcgper 1 Capsule(s)DSLD:13091
- Dr. Mercola'sWhole Food MultiVitamin900 mcgper 2 Vegetarian Capsule(s)DSLD:19771
- Dr. SinatraHeart Healthy Multivitamin Men200 mcgper 3 Tablet(s)DSLD:178533
- Dr. SinatraHeart Healthy Multivitamin Men200 mcgper 3 Tablet(s)DSLD:178564
- Dr. SinatraHeart Healthy Multivitamin Women500 mcgper 3 Tablet(s)DSLD:178748
- DrFormulasHairOmega5,000 mcgper 1 Gummy(ies)DSLD:203681
- DrFormulasHairOmega150 mcgper 2 Gummy(ies)DSLD:203701
- DrFormulasPrenatal Vitamins300 mcgper 3 Capsule(s)DSLD:203894
- Dymatize NutritionElite Fusion 7 Mochaccino Rush105 mcgper 44 Gram(s)DSLD:18731
- Emergen-CEnergy Plus Gummies Orange Zest36 mcgper 2 Gummy(ies)DSLD:202356
- Emergen-CMulti Vitamin+ Apricot-Mangoamount not statedper 9.4 Gram(s)DSLD:15919
- Emergen-CMulti Vitamin+ Cherry-Pomegranateamount not statedper 9.4 Gram(s)DSLD:15923
- Endurance Products CompanyEndur-B Complex300 mcgper 1 Tablet(s)DSLD:177916
- Energique NutritionEnervimin Stress Focus300 mcgper 4 Tablet(s)DSLD:13107
- Engage GlobalMMF100 mcgper 2 Capsule(s)DSLD:206020
- EqualineBalanced B-100 Complex100 mcgper 1 Tablet(s)DSLD:12170
- EqualineCentury Complete Multivitamin/Multimineral Supplement30 mcgper 1 Tablet(s)DSLD:12192
- EqualineChildren's Multivitamin20 mcgper 0.5 Tablet(s)DSLD:12018
- EquateChildren's Multivitamin Gummies38 mcgper 1 Gummy(ies)DSLD:178520
- EquateChildren's Multivitamin Gummies38 mcgper 1 Gummy(ies)DSLD:178679
- EquateComplete MultivitaminD-Biotin · Biotin (Form: as D-Biotin)30 mcgper 1 Tablet(s)DSLD:18989
- EquateComplete Multivitamin Adilts Under 5030 mcgper 1 Tablet(s)DSLD:18994
- EquateComplete Multivitamin Adults 50+30 mcgper 1 Tablet(s)DSLD:178537
- EquateComplete Multivitamin Adults 50+30 mcgper 1 Tablet(s)DSLD:178555
- EquateDaily Men's Adult Gummy600 mcgper 2 Gummie(s)DSLD:178691
- EquateMen's Adult Gummy Natural Berry Flavors30 mcgper 2 Gummy Vitamin(s)DSLD:178685
- EquateMen's Daily Adult Gummy600 mcgper 2 Gummie(s)DSLD:178687
- EquateOne Daily Men's Adult Gummy600 mcgper 2 Gummie(s)DSLD:178919
- EquateOne Daily Prenatal300 mcgper 1 Softgel(s)DSLD:178711
- EquateOne Daily Teen's Gummy for Her30 mcgper 2 Gummie(s)DSLD:178858
- EquateOne Daily Teen's Gummy for Him30 mcgper 2 Gummie(s)DSLD:178714
- EquateOne Daily Women's Adult Gummy150 mcgper 2 Gummie(s)DSLD:178730
- EquateWomen's Adult Gummy Natural Berry Flavors400 mcgper 2 Gummy Vitamin(s)DSLD:178910
- EquateWomen's Daily Adult Gummy150 mcgper 2 Gummie(s)DSLD:178727
- Esmond NaturalABC Plus SeniorD-Biotin · Biotin (Form: as D-Biotin)30 mcgper 1 Caplet(s)DSLD:179136
- Esmond NaturalOptimal Solutions Hair, Skin & NailsD-Biotin · Biotin (Form: as D-Biotin)3,000 mcgper 3 Caplet(s)DSLD:179112
- Essential SourceB12 Strips 2000 mcg Winter Berry2,500 mcgper 1 Strip(s)DSLD:1622
- Essential SourceB12 Strips 5 Day Energy Winter Berry2,500 mcgper 1 Strip(s)DSLD:176076
- Essential SourceyStress Great Tasting Orange Flavor!25 mcgper 1 Stick Packet(s)DSLD:176311
- Exchange SelectB-100 Complex Timed Release100 mcgper 1 Tablet(s)DSLD:200374
- Exchange SelectBiotin 10,000 mcg10,000 mcgper 1 Tablet(s)DSLD:200337
- Exchange SelectOne Daily Men's Health Formula75 mcgper 1 Tablet(s)DSLD:204401
- FemMedMulti + Antioxidants300 mcgper 2 Capsule(s)DSLD:19214
- FemMedPregnancy45 mcgper 2 Capsule(s)DSLD:19212
- FemMedPregnancy + Ginger45 mcgper 3 Capsule(s)DSLD:19213
- FINAFLEXActive Multi25 mcgper 4 Capsule(s)DSLD:177865
- FINAFLEXActive Multi25 mcgper 4 Capsule(s)DSLD:177761
- Finest NaturalMen's 50+ AdvancedD-Biotin · Biotin (Form: as D-Biotin)30 mcgper 1 Capsule(s)DSLD:13254
- Finest NaturalTimed Release B-100 B-Complex Vitamins100 mcgper 1 Caplet(s)DSLD:13167
- Focus FactorBrain & Vision300 mcgper 4 Tablet(s)DSLD:175969
- Focus FactorFocus Factor Extra Strength300 mcgper 4 Tablet(s)DSLD:176012
- Focus FactorFOCUSfactor300 mcgper 4 Tablet(s)DSLD:181003
- FOCUSfactorFocusFactor300 mcgper 4 Tablet(s)DSLD:2037
- Garden of LifeRAW One For Women150 mcgper 1 Capsule(s)DSLD:174605
- Garden Of LifeRAW One For Men150 mcgper 1 Capsule(s)DSLD:174600
- Garden of Life MyKind OrganicsMen's Multi 40+ Organic BerryBiotin Note: Certified Organic Real Food Vitamin Blend114 mcgper 4 Gummy(ies)DSLD:173803
- Garden of Life MyKind OrganicsWomen's Multi 40+ Organic BerryBiotin Note: Certified Organic Real Food Vitamin Blend114 mcgper 4 Gummy(ies)DSLD:173916
- Garden Of Life MyKind OrganicsMen's Multi Organic BerryBiotin Note: Certified Organic Real Food Vitamin Blend105 mcgper 4 Gummy(ies)DSLD:173888
- Garden Of Life MyKind OrganicsWomen's Multi Organic BerryBiotin Note: Certified Organic Real Food Vitamin Blend105 mcgper 4 Gummy(ies)DSLD:173918
- Genceutic NaturalsPlant Head Men's FormulaD-Biotin · Biotin (Form: as D-Biotin)30 mcgper 31 Gram(s)DSLD:184738
- Genceutic NaturalsPlant Head Original GreensD-Biotin · Biotin (Form: as D-Biotin)30 mcgper 8.5 Gram(s)DSLD:184227
- Genestra BrandsLiquid B Complex Natural Cherry Flavor200 mcgper 1 tspDSLD:176563
- Genestra BrandsOrti B300 mcgper 1 Capsule(s)DSLD:202733
- Geri-CareAdult High Potency Multi-Vitamin Multi-Mineral Liquid300 mcgper 1 TbspDSLD:176990
- Geri-CareThera-Tabs30 mcgper 1 Caplet(s)DSLD:176725
- Geri-CareVitamin B - Complex30 mcgper 1 Tablet(s)DSLD:176913
- Glow by Nature MadeSkin Moisture + Hair & Nails2,500 mcgper 2 Softgel(s)DSLD:179916
- GNC AMP Advanced Muscle PerformanceMega Men Sport Multivitamin300 mcgper 2 Mocha Brown Caplet(s)DSLD:183541
- GNC Beyond RawRe-Power Fruit Punch900 mcgper 18.57 Gram(s)DSLD:13233
- GNC Beyond RawRe-Power Orange900 mcgper 18.06 Gram(s)DSLD:13240
- GNC Mega MenMega Men300 mcgper 2 Caplet(s)DSLD:19423
- GNC Mega MenMega Men 50 Plus300 mcgper 2 Caplet(s)DSLD:15713
- GNC Mega MenMega Men Citrus100 mcgper 2 TbspDSLD:14015
- GNC Mega MenSport Milk Chocolate300 mcgper 36 Gram(s)DSLD:1060
- GNC Mega MenSport Vanilla Bean300 mcgper 36 Gram(s)DSLD:1061
- GNC Men'sMega Men Sport300 mcgper 2 Brown Caplet(s)DSLD:191080
- GNC Pro PerformanceLean Muscle Meal Chocolateamount not statedper 69 Gram(s)DSLD:16801
- GNC Pro PerformanceLean Muscle Meal Vanillaamount not statedper 68 Gram(s)DSLD:16846
- GNC Pro Performance AMPAmplified Endurance Booster Blue Raspberry25 mcgper 60 Gram(s)DSLD:18529
- GNC Pro Performance AMPBiotin 50005,000 mcgper 1 White Capsule(s)DSLD:176179
- GNC Pro Performance AMPWomen's Ultra Mega Active Without Iron300 mcgper 2 Light Green Caplet(s)DSLD:176166
- GNC SuperFoodsBeauty, Antioxidant, Stress & ImmuneBiotin · Biotin (Form: as cultured Biotin Note: cultured on rice protein, yeast, molasses, papain, bromelain, gum arabic, and maltodextrin)1,000 mcgper 1 Capsule(s)DSLD:176273
- GNC SuperFoodsBrewer's Yeast Vitality Complex300 mcgper 2 Capsule(s)DSLD:176189
- GNC SuperFoodsUltra Mega Green Women's Multivitamin300 mcgper 2 Light Green Caplet(s)DSLD:176181
- GNC SuperFoodsUltra Mega Green Women's Multivitamin300 mcgper 2 Light Green Caplet(s)DSLD:176249
- GNC Total Lean AdvancedLean Shake Burn Cookies & Cream75 mcgper 23.25 Gram(s)DSLD:182149
- GNC Women'sOne Daily Multivitamin300 mcgper 1 Caplet(s)DSLD:200362
- GNC Women's Ultra MegaActive Milk Chocolate300 mcgper 35 Gram(s)DSLD:1062
- GNC Women's Ultra MegaActive Vanilla Creme300 mcgper 35 Gram(s)DSLD:1063
- GNC Women's Ultra MegaEnergy & Metabolism One Daily300 mcgper 1 Caplet(s)DSLD:200358
- GNC Women's Ultra MegaEnergy And Metabolism300 mcgper 2 Caplet(s)DSLD:12031
- GNC Women's Ultra MegaUltra Mega Citrus100 mcgper 30 mLDSLD:14391
- GNC Women's Ultra MegaWomen's Ultra Mega With Probiotics300 mcgper 4 Capsule(s)DSLD:1658
- GNC Women's Ultra MegaWomen's Ultra Mega Without Iron & Iodine300 mcgper 2 Caplet(s)DSLD:15697
- GNC Women's Ultra MegaWomen's Ultra Mega Without Iron And Iodine300 mcgper 2 Tablet(s)DSLD:19458
- Goliath LabsGoliath Multi Vitamin300 mcgper 4 Tablet(s)DSLD:12360
- Goliath LabsVitamonster250 mcgper 2 Tablet(s)DSLD:177347
- GoodSenseCentury Women40 mcgper 1 Tablet(s)DSLD:206515
- Greens TodayJoint Formula French Vanilla Flavor300 mcgper 15 Gram(s)DSLD:11568
- Greens TodayVegan Formula300 mcgper 17 Gram(s)DSLD:11471
- Greens++PlusShake Raw Chocolate1.2 mcgper 42 Gram(s)DSLD:180959
- Greens++PlusShake Raw Vanilla1 mcgper 41 Gram(s)DSLD:180971
- Greens+ OrganicsSuperfood Amazon Chocolate2 mcgper 8 Gram(s)DSLD:180934
- Greens+ OrganicsSuperfood Wild Berry3 mcgper 8 Gram(s)DSLD:180955
- HCF Happy, Calm, FocusedHCF Happy, Calm, Focused150 mcgper 3 Capsule(s)DSLD:20030
- HealFastPost-Op & Injury Recovery Support Formula25 mcgper 4 Tablet(s)DSLD:176433
- Health Thru Nutrition NaturallyPhysician's MultiVitamin Formula100 mcgper 1 Caplet(s)DSLD:177596
- Health Thru Nutrition NaturallyUltraBetic Multi-Vitamin300 mcgper 1 Caplet(s)DSLD:177716
- Healthy Choice NaturalsHair, Skin, & Nail essentials2,600 mcgper 1 Capsule(s)DSLD:16991
- Herbal CleanUltra Eliminex Tropical Fruit Flavor148 mcgper 32 fl. Oz.DSLD:183340
- Hero Nutritionals Slice of Life OrganicsMen's CompleteD-Biotin · Biotin (Form: as D-Biotin Note: USP)150 mcgper 3 Slice(s)DSLD:181082
- Hero Nutritionals Slice of Life OrganicsPrenatal PlusBiotin Note: USP75 mcgper 3 Slice(s)DSLD:181091
- Hero Nutritionals Slice of Life OrganicsWomen's CompleteD-Biotin · Biotin (Form: as D-Biotin Note: USP)300 mcgper 3 Slice(s)DSLD:181134
- Hero Nutritionals Yummi BearsMulti-Vitamin & MineralBiotin · Biotin (Form: as Biotin)70 mcgper 1 Gummy(ies)DSLD:13419
- Hero Nutritionals Yummi BearsMulti-Vitamin & MineralBiotin · Biotin (Form: as Biotin)70 mcgper 1 Gummy(ies)DSLD:18500
- Hero Nutritionals Yummi Bears Organics SuperMulti + OmegaBiotin Note: USP30 mcgper 3 Bear(s)DSLD:181163
- Hero Nutritionals Yummi Bears Sugar FreeMulti-Vitamin & MineralBiotin · Biotin (Form: as Biotin)70 mcgper 1 Gummy(ies)DSLD:14399
- Hero Nutritionals Yummi Bears SuperMulti + OmegaBiotin Note: USP30 mcgper 3 Bear(s)DSLD:204089
- Hi-Tech PharmaceuticalsDicobalene-V Cherry Flavored25 mcgper 1 Tablet(s)DSLD:10262
- Hi-Tech PharmaceuticalsFastin Multi-Vite For Her120 mcgper 2 Tablet(s)DSLD:19302
- Hi-Tech PharmaceuticalsHi-Tech Multi-Vitamin With Minerals100 mcgper 1 Tablet(s)DSLD:10291
- Hi-Tech PharmaceuticalsNitroPro Double Dutch Chocolate - Flavor150 mcgper 92 Gram(s)DSLD:10248
- Hi-Tech PharmaceuticalsNitroPro Fresh Strawberry Milkshake - Flavor150 mcgper 92 Gram(s)DSLD:10253
- Hi-Tech PharmaceuticalsNitroPro Orange Creamsicle - Flavor150 mcgper 92 Gram(s)DSLD:10251
- Hi-Tech PharmaceuticalsNitroPro Vanilla Milkshake - Flavor150 mcgper 92 Gram(s)DSLD:10254
- Higher NatureKeep Sharp30 mcgper 1 Jelly(s)DSLD:178205
- HoltraCeuticalsBig Hair187.5 mcgper 3 Capsule(s)DSLD:19258
- HoltraCeuticalsDaily Energy Elements Chocolate Flavored500 mcgper 25.1 Gram(s)DSLD:19405
- HoltraCeuticalsDaily Energy Elements High Octane Additive100 mcgper 4 Capsule(s)DSLD:19456
- HoltraCeuticalsGluco SX4,000 mcgper 3 Capsule(s)DSLD:19444
- HoltraCeuticalsGlucorol SX4,000 mcgper 3 Capsule(s)DSLD:19388
- HoltraCeuticalsGut Feeling125 mcgper 2 Capsule(s)DSLD:19445
- HoltraCeuticalsMax-B75 mcgper 1 Capsule(s)DSLD:19636
- HoltraCeuticalsMultiplex400 mcgper 4 Capsule(s)DSLD:19698
- HoltraCeuticalsMultiplex With Iron400 mcgper 4 Capsule(s)DSLD:19850
- Home HealthPre-Natal Multi-Vitamin Multi-Mineral Supplement240 mcgper 2 Tablet(s)DSLD:19369
- Hyalogic Beauty from WithinHair, Skin & Nails5,000 mcgper 1 Lozenge(s)DSLD:201483
- HydroxycutHydroxycut Gummies Mixed Fruit105 mcgper 3 Gummie(s)DSLD:182418
- HydroxycutHydroxycut Platinum118 mcgper 1 Capsule(s)DSLD:182543
- i-HealthPrenatal Multivitamin Tablet330 mcgper 1 Prenatal Multivitamin Tablet(s)DSLD:182723
- Infiniti CreationsDiatriX Extreme! Diabetic Supplementamount not statedper 1 Capsule(s)DSLD:19107
- Infiniti CreationsPAGG Night Time FormulaD-Biotin100 mcgper 1 Capsule(s)DSLD:19234
- Innate Response FormulasClear Response Vanilla150 mcgper 27 Gram(s)DSLD:177902
- Innate Response FormulasComplete Multi PowderBroccoli · Biotin (Form: FoodState Nutrient (Form: sources: Brown Rice, Carrot, Broccoli, Cabbage))300 mcgper 6.5 Gram(s)DSLD:177941
- Innate Response FormulasFood Multi III BioMax150 mcgper 3 Tablet(s)DSLD:178023
- Innate Response FormulasFood Multi III BioMax150 mcgper 3 Tablet(s)DSLD:178029
- Innate Response FormulasOne Daily CapBroccoli · Biotin (Form: FoodState Nutrient (Form: sources: Broccoli, Brown Rice, Carrot))300 mcgper 1 Capsule(s)DSLD:177868
- Innate Response FormulasWomen Over 40200 mcgper 2 Tablet(s)DSLD:178001
- Innate Response FormulasWomen's Multi225 mcgper 2 Tablet(s)DSLD:178005
- Innate Response FormulasWomen's One Daily150 mcgper 1 Tablet(s)DSLD:178016
- Integrative TherapeuticsBiotin Forte5 mgper 1 Tablet(s)DSLD:185031
- Integrative TherapeuticsClinical Nutrients 45 - Plus Women600 mcgper 3 Tablet(s)DSLD:184957
- Integrative TherapeuticsClinical Nutrients 50-Plus Men Iron-Free600 mcgper 4 Tablet(s)DSLD:185018
- Integrative TherapeuticsClinical Nutrients For Men600 mcgper 3 Tablet(s)DSLD:184898
- Integrative TherapeuticsClinical Nutrients For Women600 mcgper 3 Tablet(s)DSLD:184848
- Integrative TherapeuticsK-Pax Mitonutrient Activator25 mcgper 1 Tablet(s)DSLD:201112
- Integrative TherapeuticsPrenatal Forte100 mcgper 2 Tablet(s)DSLD:201187
- International Vitamin CorporationSpongeBob Squarepants Gummies38 mcgper 1 Gummy(ies)DSLD:19883
- International Vitamin CorporationZ-BEC300 mcgper 1 Caplet(s)DSLD:201674
- Iron-TekLiquid Amino Complex Natural Orange FlavorD-Biotin · Biotin (Form: as D-Biotin)10 mcgper 3 TbspDSLD:14276
- Irwin KidsBerryLicious Super Multi Sweet Berry300 mcgper 0.5 Soft Chew(s)DSLD:13433
- IsotonixMultivitamin300 mcgper 3.3 Gram(s)DSLD:202681
- IsotonixMultivitamin with Iron300 mcgper 3.3 Gram(s)DSLD:202669
- IVL Institute For Vibrant LivingAdult Food-Based Multi300 mcgper 1 Tablet(s)DSLD:15316
- IVL Institute For Vibrant LivingAll Day Energy Greens350 mcgper 10 Gram(s)DSLD:175000
- IVL Institute For Vibrant LivingChewable Kids' Multi50 mcgper 2 Tablet(s)DSLD:15380
- IVL Institute For Vibrant LivingFood Based Women's Multi Comprehensive Formula300 mcgper 2 Tablet(s)DSLD:15433
- IVL Institute For Vibrant LivingUltimate B Complex150 mcgper 2 Vegetarian Tablet(s)DSLD:15363
- IVL Institute For Vibrant LivingVShake62 mcgper 37.45 Gram(s)DSLD:15648
- JuvenonHealthy Aging Support300 mcgper 2 Tablet(s)DSLD:19896
- Kirkland SignatureDaily Multi Vitamins & Minerals30 mcgper 1 Tablet(s)DSLD:19196
- KrogerComplete30 mcgper 1 Tablet(s)DSLD:12166
- KyaniSunriseBiotin Note: USP150 mcgper 1 tspDSLD:200584
- L'il CrittersFruit n' Honey Complete Multivitamin Natural Berry Flavor30 mcgper 1 Gummy(ies)DSLD:176873
- L'il CrittersGummy Vites Complete60 mcgper 1 Gummy(ies)DSLD:19249
- Labrada NutritionLean Body Vanilla Ice Cream Flavoramount not statedper 70 Gram(s)DSLD:183391
- Lee Haney's Nutritional Support SystemsLife's Vitality Multi Vitamin/Mineral Complex100 mcgper 1 Tablet(s)DSLD:13008
- Life ExtensionLife Extension Mix Tablets3,000 mcgper 8 Tablet(s)DSLD:182627
- Life ExtensionLife Extension Mix Tablets with Extra Niacin3,000 mcgper 8 Tablet(s)DSLD:182633
- Life ExtensionLife Extension Mix Tablets without Copper3,000 mcgper 8 Tablet(s)DSLD:182644
- Life ExtensionOne-Per-Day Tablets300 mcgper 1 Tablet(s)DSLD:182576
- Life ExtensionTwo-Per-Day Capsules300 mcgper 2 Capsule(s)DSLD:182714
- LifeLinkBiotin 55 mgper 1 Tablet(s)DSLD:11836
- LifeLinkPlatform150 mcgper 6 Caplet(s)DSLD:11852
- LifeMiracle USALiquiVive Comprehensive Wellness Formula120 mcgper 2 TbspDSLD:19925
- Lifestyle Fitness & NutritionDaily Complete Multi-Vitamin/Mineral Complex100 mcgper 1 Tablet(s)DSLD:16970
- Lyfe FuelAll-In-One Daily Essentials Shake Chocolate150 mcgper 32 Gram(s)DSLD:177010
- Lyfe FuelAll-In-One Daily Essentials Shake Vanilla Chai150 mcgper 32 Gram(s)DSLD:177043
- MajorAnimal Shapes with Iron40 mcgper 0.5 Tablet(s)DSLD:201864
- MajorAnimal Shapes with Iron40 mcgper 0.5 Tablet(s)DSLD:202385
- MajorBiotin 300 mcg300 mcgper 1 Tablet(s)DSLD:202028
- MajorCertaVite Senior30 mcgper 1 Tablet(s)DSLD:202002
- MajorStress Formula45 mcgper 1 Tablet(s)DSLD:202067
- MajorStress Formula with Iron45 mcgper 1 Tablet(s)DSLD:202155
- MajorStress Formula with Zinc45 mcgper 1 Tablet(s)DSLD:201852
- MajorThera30 mcgper 1 Tablet(s)DSLD:201949
- MajorThera30 mcgper 1 Tablet(s)DSLD:201951
- Major PharmaceuticalsThera M Plus Tablets30 mcgper 1 Tablet(s)DSLD:202052
- Major PharmaceuticalsThera Tablets30 mcgper 1 Tablet(s)DSLD:202055
- Martin Avenue PharmacyBone Total Health300 mcgper 4 Tablet(s)DSLD:18801
- Martin Avenue PharmacyBrain Total Health300 mcgper 4 Tablet(s)DSLD:19531
- Martin Avenue PharmacyCardio Total Health300 mcgper 4 Tablet(s)DSLD:19532
- Martin Avenue PharmacyChildren's Essentials Multivitamin & Mineral150 mcgper 1 Tablet(s)DSLD:19533
- Martin Avenue PharmacyEssentials Multivitamin And Mineral75 mcgper 1 Tablet(s)DSLD:19543
- Martin Avenue PharmacyEssentials Multivitamin And Mineral Without Iron75 mcgper 1 Tablet(s)DSLD:19553
- Martin Avenue PharmacyEssentials Perfomance Formula MultiVitamin And Mineral17 mcgper 1 Tablet(s)DSLD:19557
- Martin Avenue PharmacyEssentials Performance UltraMax MultiVitamin And Mineral300 mcgper 6 Tablet(s)DSLD:19572
- Martin Avenue PharmacyGluco Total Health300 mcgper 4 Tablet(s)DSLD:19575
- Martin Avenue PharmacyGlucose Control Support With Gymnema Sylvestre2,500 mcgper 2 Capsule(s)DSLD:19344
- Martin Avenue PharmacyO.C. Pill Rx Depletion100 mcgper 1 Capsule(s)DSLD:19470
- Martin Avenue PharmacySuper Stress Support With B-Complex, Vitamin C, And Valerian100 mcgper 1 Tablet(s)DSLD:19603
- Martin Avenue PharmacyVitamin B-Complex 100 mg100 mcgper 1 Tablet(s)DSLD:19525
- Martin Avenue PharmacyWomen's Total Health MultiVitamin And Mineral200 mcgper 6 Tablet(s)DSLD:19607
- Marz SpraysKids Spray150 mcgper 1 mLDSLD:16323
- Marz SpraysSlim Spray Extra Lean Weight Loss Support300 mcgper 1 mLDSLD:16331
- Mason NaturalBiotin 10,000 mcg Plus Keratin 100 mgD-Biotin · Biotin (Form: D-Biotin) Note: 10,000 mcg10 mgper 1 Tablet(s)DSLD:202070
- Meaningful Beauty WellnessComplete Beauty Complex200 mcgper 2 Tablet(s)DSLD:178254
- MegaFoodKids Daily B-Centered300 mcgper 1.07 Gram(s)DSLD:177500
- MegaFoodWomen's One Daily California BlendBrown Rice · Biotin (Form: with organic Brown Rice)30 mcgper 1 Tablet(s)DSLD:177369
- MegaFoodWomen's One Daily California BlendBrown Rice · Biotin (Form: with organic Brown Rice)30 mcgper 1 Tablet(s)DSLD:178051
- MegaFoodWomen's One Daily California BlendBrown Rice · Biotin (Form: with organic Brown Rice)30 mcgper 1 Tablet(s)DSLD:178096
- MelaleucaVitality 6 Essentials + HeartD-Biotin · Biotin (Form: as D-Biotin)150 mcgper 1 Packet(s)DSLD:13664
- MelaleucaVitality TotalD-Biotin · Biotin (Form: as D-Biotin)30 mcgper 1 Packet(s)DSLD:13621
- MET-RxActive Multi PacksD-Biotin · Biotin (Form: as D-Biotin)500 mcgper 1 Packet(s)DSLD:15488
- MET-RxMET Rx Meal Replacement Chocolate Peanut Butteramount not statedper 72 Gram(s)DSLD:20101
- MET-RxMET-Rx Meal Replacement Cake Batteramount not statedper 72 Gram(s)DSLD:18120
- MET-RxMET-Rx Meal Replacement Extreme Chocolateamount not statedper 72 Gram(s)DSLD:18124
- MET-RxMET-Rx Meal Replacement Original Vanillaamount not statedper 72 Gram(s)DSLD:18128
- MET-RxRTD 51 Cookies & Cremeamount not statedper 1 Can(s)DSLD:181848
- MET-RxRTD 51 Creamy Vanillaamount not statedper 1 Can(s)DSLD:181825
- MET-RxRTD 51 Frosty Chocolateamount not statedper 1 Can(s)DSLD:181840
- MET-RxRTD 51 Peanut Butter Cupamount not statedper 1 Can(s)DSLD:181841
- MET-Rx 180(0)Essential MultiD-Biotin · Biotin (Form: as D-Biotin)30 mcgper 1 Tablet(s)DSLD:15767
- MET-Rx 180(0)Recovery Shake Chocolate45 mcgper 42 Gram(s)DSLD:15765
- MET-Rx 180(0)Recovery Shake Vanilla45 mcgper 42 Gram(s)DSLD:15757
- Metabolic NutritionProtiZyme Banana Cremeamount not statedper 35 Gram(s)DSLD:180076
- Metabolic NutritionProtiZyme Butter Pecan Cookieamount not statedper 35 Gram(s)DSLD:180086
- Metabolic NutritionProtiZyme Chocolate Cakeamount not statedper 35 Gram(s)DSLD:180089
- Metabolic NutritionProtiZyme Peanut Butter Cookieamount not statedper 35 Gram(s)DSLD:180100
- Metabolic NutritionProtiZyme Strawberry Cremeamount not statedper 35 Gram(s)DSLD:180105
- Metabolic NutritionProtiZyme Vanilla Cakeamount not statedper 35 Gram(s)DSLD:180108
- MHP Maximum Human PerformanceUp Your Mass CinnaBunamount not statedper 132 Gram(s)DSLD:19190
- MHP Maximum Human PerformanceUp Your Mass Fudge Brownieamount not statedper 132 Gram(s)DSLD:19180
- MHP Maximum Human PerformanceUp Your Mass Vanillaamount not statedper 132 Gram(s)DSLD:19193
- Michael's Naturopathic ProgramsFor Men Daily Multi Vitamin500 mcgper 2 Tablet(s)DSLD:174297
- Miller Pharmacal GroupTheramill Forte50 mcgper 2 Capsule(s)DSLD:177113
- Moss NutritionSacroSelect50 mcgper 41.8 Gram(s)DSLD:191046
- Moss NutritionSelect Meal DF Chocolate300 mcgper 46.5 Gram(s)DSLD:191101
- Moss NutritionSelect Meal DF Vanilla300 mcgper 45.9 Gram(s)DSLD:191111
- Moss NutritionSelect Meal Vanilla300 mcgper 50.7 Gram(s)DSLD:193368
- MRI EnduranceEO2 Edge Cola150 mcgper 15 Gram(s)DSLD:15791
- MRI EnduranceEO2 Edge Tropical Punch150 mcgper 15 Gram(s)DSLD:15800
- MusclePharmShred Matrix150 mcgper 3 Capsule(s)DSLD:18006
- MuscleTech Essential SeriesPlatinum Multi Vitamin165 mcgper 3 Caplet(s)DSLD:182566
- MuscleTech Performance SeriesMASS TECH Extreme 2000 Triple Chocolate Brownie158 mcgper 285 Gram(s)DSLD:182773
- MuscleTech Performance SeriesMASS TECH Extreme 2000 Vanilla Milkshake158 mcgper 285 Gram(s)DSLD:182876
- myDNAhealthSugar Blockpure Biotin1 mgper 2 Capsule(s)DSLD:199720
- MyTritionBiotin Advanced5,000 mcgper 1 Tablet(s)DSLD:180794
- MyTritionCoenzymated B-ComplexD-Biotin · Biotin (Form: as D-Biotin)300 mcgper 2 Vegetarian Capsule(s)DSLD:175481
- MyTritionMultivitamin+EnergyD-Biotin · Biotin (Form: as D-Biotin)60 mcgper 1 Veggie Capsule(s)DSLD:175329
- Native RemediesNR Essentials Multivitamin For Women500 mcgper 3 Capsule(s)DSLD:13805
- NatrolB-100 Complex100 mcgper 1 Tablet(s)DSLD:203119
- NatrolBiotin 10,000 mcg Maximum Strength Strawberry10,000 mcgper 1 Tablet(s)DSLD:174465
- NatrolBiotin 5,000 mcg Extra Strength5,000 mcgper 1 Tablet(s)DSLD:174331
- NatrolHair, Skin & Nails Raspberry5,000 mcgper 2 Gummy(ies)DSLD:203628
- Natural ClinicianClinical Glycemia1,000 mcgper 1 Capsule(s)DSLD:18625
- Natural ClinicianClinical Metabolic Syndrome X Nutritional Factors300 mcgper 1 Capsule(s)DSLD:18642
- Natural ClinicianClinical Prostate Suppport6 mcgper 2 Capsule(s)DSLD:18677
- Natural FactorsSlimStyles Weight Loss Drink Mix Very Strawberry75 mcgper 31.5 Gram(s)DSLD:181578
- Natural Factors SlimStylesWeight Loss Drink Mix French Vanilla75 mcgper 31 Gram(s)DSLD:179497
- Nature MadeBiotin 1000 mcg1,000 mcgper 1 Softgel(s)DSLD:180371
- Nature MadeBiotin Adult Gummies 3000 mcg3,000 mcgper 2 Gummie(s)DSLD:180096
- Nature MadeDiabetes Health Pack30 mcgper 1 Packet(s)DSLD:179514
- Nature MadeDigestive Probiotics + Multivitamins Women's Dual Action30 mcgper 1 Tablet(s)DSLD:180293
- Nature MadeHair-Skin-Nails Adult Gummies2,500 mcgper 2 Gummie(s)DSLD:180263
- Nature MadeHair-Skin-Nails Adult Gummies2,500 mcgper 2 Gummie(s)DSLD:180364
- Nature MadeHair, Skin, & Nails2,500 mcgper 1 Softgel(s)DSLD:179960
- Nature MadeHair, Skin, & Nails2,500 mcgper 1 Softgel(s)DSLD:180360
- Nature MadeHair, Skin, & Nails2,500 mcgper 1 Softgel(s)DSLD:180367
- Nature MadeHigh Potency Biotin 2500 mcg2,500 mcgper 1 Softgel(s)DSLD:180146
- Nature MadeHigh Potency Biotin 2500 mcg2,500 mcgper 1 Softgel(s)DSLD:179651
- Nature MadeHigh Potency Biotin 2500 mcg2,500 mcgper 1 Softgel(s)DSLD:179658
- Nature MadeHigh Potency Biotin 2500 mcg2,500 mcgper 1 Softgel(s)DSLD:179952
- Nature MadeMaximin Pack130 mcgper 1 Packet(s)DSLD:179317
- Nature MadeMaximum Strength Biotin 5,000 mcgVitamin B75,000 mcgper 1 Softgel(s)DSLD:179750
- Nature MadeMaximum Strength Biotin 5,000 mcgVitamin B75,000 mcgper 1 Softgel(s)DSLD:179953
- Nature MadeMaximum Strength Biotin 5,000 mcgVitamin B75,000 mcgper 1 Softgel(s)DSLD:180191
- Nature MadeMen's Pack30 mcgper 1 Packet(s)DSLD:179309
- Nature MadeMulti Adult Gummies150 mcgper 2 Gummie(s)DSLD:180149
- Nature MadeMulti Adult Gummies150 mcgper 2 Gummie(s)DSLD:180275
- Nature MadeMulti Complete30 mcgper 1 Softgel(s)DSLD:180237
- Nature MadeMulti Complete With Iron30 mcgper 1 Tablet(s)DSLD:179537
- Nature MadeMulti For Her 50+ No Iron30 mcgper 1 Tablet(s)DSLD:179563
- Nature MadeMulti for Her plus Omega-3s Adult Gummies100 mcgper 2 Gummie(s)DSLD:180302
- Nature MadeMulti for Her plus Omega-3s Adult Gummies100 mcgper 2 Gummie(s)DSLD:180313
- Nature MadeMulti For Her With Iron & Calcium30 mcgper 1 Tablet(s)DSLD:179864
- Nature MadeMulti For Him30 mcgper 1 Tablet(s)DSLD:179550
- Nature MadeMulti For Him30 mcgper 1 Tablet(s)DSLD:179944
- Nature MadeMulti For Him30 mcgper 1 Softgel(s)DSLD:180184
- Nature MadeMutli for Him plus Omega-3s Adult Gummies30 mcgper 2 Gummie(s)DSLD:180141
- Nature MadePostnatal Multi + DHA35 mcgper 1 Softgel(s)DSLD:179871
- Nature MadePostnatal Multi + DHA35 mcgper 1 Softgel(s)DSLD:180109
- Nature MadePrenatal Multi + DHA30 mcgper 1 Softgel(s)DSLD:180316
- Nature MadeStress B-Complex45 mcgper 1 Tablet(s)DSLD:179758
- Nature MadeStress B-Complex45 mcgper 1 Tablet(s)DSLD:180112
- Nature MadeSuper B Energy Complex300 mcgper 1 Softgel(s)DSLD:179918
- Nature MadeSuper B-Complex30 mcgper 1 Tablet(s)DSLD:179762
- Nature MadeSuper B-Complex30 mcgper 1 Tablet(s)DSLD:179768
- Nature MadeSuper B-Complex30 mcgper 1 Tablet(s)DSLD:179966
- Nature MadeSuper B-Complex30 mcgper 1 Tablet(s)DSLD:179996
- Nature MadeSuper B-Complex30 mcgper 1 Tablet(s)DSLD:180114
- Nature MadeSuper B-Complex30 mcgper 1 Tablet(s)DSLD:180195
- Nature MadeSuper B-Complex30 mcgper 1 Tablet(s)DSLD:180430
- Nature MadeTriple Probiotic133 mcgper 1 Caplet(s)DSLD:19071
- Nature Made Kids FirstMultivitamin Gummies75 mcgper 1 Gummy(ies)DSLD:179610
- Nature Made VitaMeltsHair-Skin-Nails Strawberry Lemonade2,500 mcgper 2 Tablet(s)DSLD:180253
- Nature Made VitaMeltsHair-Skin-Nails Strawberry Lemonade2,500 mcgper 2 Tablet(s)DSLD:180269
- Nature Made VitaMeltsMultivitamin Tropical Fruit300 mcgper 3 Tablet(s)DSLD:180257
- Nature Made VitaMeltsMultivitamin Tropical Fruit300 mcgper 3 Tablet(s)DSLD:180270
- Nature's AnswerMulti-Daily Vitamins & Minerals300 mcgper 1 Tablet(s)DSLD:16800
- Nature's BountyHair, Skin & NailsD-Biotin · Biotin (Form: as D-Biotin) Note: 3 g3,000 mcgper 3 Caplet(s)DSLD:17384
- Nature's BountyYour Life Multi Green SouceD-Biotin · Biotin (Form: as D-Biotin)300 mcgper 3 Caplet(s)DSLD:17328
- Nature's Bounty Optimal SolutionsComplete PMSD-Biotin · Biotin (Form: as d-Biotin)300 mcgper 2 Softgel(s)DSLD:15871
- Nature's Bounty Optimal SolutionsComplete Vitamin Shake Mix ChocolateD-Biotin · Biotin (Form: as D-Biotin)300 mcgper 33 Gram(s)DSLD:15920
- Nature's LabOne Daily Multivitamin500 mcgper 1 Capsule(s)DSLD:205404
- Nature's WayAlive! Children's Chewable Multi-Vitamin100 mcgper 2 Chewable Tablet(s)DSLD:201803
- Nature's WayAlive! Prenatal Multi-Vitamin with Plant DHA Strawberry FlavoredVitamin B7300 mcgper 1 Softgel(s)DSLD:201812
- Nature's WayB-Stress Formula with Eleuthero150 mcgper 1 Capsule(s)DSLD:200878
- Nature's WayFortify Dual Action Energy Support 20 Billion30 mcgper 1 Capsule(s)DSLD:201939
- Nature's WayLiv-A-Tox200 mcgper 3 Tablet(s)DSLD:201480
- Natures Plus Keto LivingDaily Multi1,500 mcgper 3 Capsule(s)DSLD:200801
- NatureSmartAnatherm Heat Metabolics StimulatorD-Biotin · Biotin (Form: as D-Biotin)180 mcgper 1 Capsule(s)DSLD:1300
- NatureSmartDisney My First Gummies Multi Vitamin45 mcgper 2 Gummy(ies)DSLD:12265
- New Chapter55+ Every Man's One Daily MultiBiotin Note: from ferment media150 mcgper 1 Tablet(s)DSLD:201903
- New Chapter55+ Every Man's One Daily MultiBiotin Note: from ferment media150 mcgper 1 Tablet(s)DSLD:201910
- New Chapter55+ Every Woman's One Daily MultiBiotin Note: from ferment media150 mcgper 1 Tablet(s)DSLD:201860
- New Chapter55+ Every Woman's One Daily MultiBiotin Note: from ferment media150 mcgper 1 Tablet(s)DSLD:201869
- New ChapterCoenzyme B Food ComplexBiotin Note: from culture media300 mcgper 1 Tablet(s)DSLD:178370
- New ChapterCoenzyme B Food ComplexBiotin Note: from culture media300 mcgper 1 Tablet(s)DSLD:181241
- New ChapterPerfect Energy MultivitaminBiotin Note: from culture media300 mcgper 3 Tablet(s)DSLD:181233
- New ChapterPerfect Energy MultivitaminBiotin Note: from culture media300 mcgper 3 Tablet(s)DSLD:181239
- New ChapterPerfect Hair, Skin & NailsBiotin Note: from culture media300 mcgper 1 Capsule(s)DSLD:181101
- New ChapterPerfect Postnatal MultivitaminBiotin Note: from ferment media35 mcgper 3 Tablet(s)DSLD:201811
- New Chapter OrganicsEvery Man's One Daily150 mcgper 1 Tablet(s)DSLD:17992
- New SunAdvanced Mineral Complex Plus300 mcgper 1 fl. Oz.DSLD:203574
- New SunHigh Potency Multiple Vitamins100 mcgper 2 Tablet(s)DSLD:203793
- New SunHigh Potency Multiple Vitamins100 mcgper 2 Tablet(s)DSLD:203902
- New SunLiquid Multiple Vitamin And Mineral Tropical Orange Flavor100 mcgper 0.33 TbspDSLD:12453
- New SunUltra Calm50 mcgper 1 Tablet(s)DSLD:11781
- New SunVita ChewsVitamin B7150 mcgper 1 Tablet(s)DSLD:11710
- New SunYeast Free B Complex100 mcgper 2 Tablet(s)DSLD:12445
- Newflower Farmers MarketsB-Complex 5050 mcgper 1 Capsule(s)DSLD:17171
- Newflower Farmers MarketsB-Complex 5050 mcgper 1 Capsule(s)DSLD:17173
- Newflower Farmers MarketsB-Complex 5050 mcgper 1 Tablet(s)DSLD:17179
- Newflower Farmers MarketsCoenzyme-B B-50 Complex200 mcgper 1 Vegetarian Capsule(s)DSLD:17201
- Nikken Wellness KenzenMega Daily 4 for Men300 mcgper 4 Tablet(s)DSLD:200768
- Noor VitaminsAdult Multi-Gummies with Organic Fruit Blend120 mcgper 3 Gummie(s)DSLD:183227
- Noor VitaminsChildren's Gummies60 mcgper 1 Gummy(ies)DSLD:183290
- Noor VitaminsComplete Prenatal300 mcgper 1 Tablet(s)DSLD:183341
- Noor VitaminsEnergy +300 mcgper 1 Tablet(s)DSLD:183305
- Noor VitaminsHair & Skin Strawberry Flavor5,000 mcgper 2 Gummie(s)DSLD:183242
- Noor VitaminsMulti-Vitamin and Mineral30 mcgper 1 Tablet(s)DSLD:183315
- Noor VitaminsPre & Post Natal DHA + Iron Fruit Flavored300 mcgper 3 Gummie(s)DSLD:183318
- NOWB-50 Powder100 mcgper 0.25 tspDSLD:14289
- NOWMulti-Food Complex For Men300 mcgper 2 Tablet(s)DSLD:15661
- NOWMulti-Food Complex For Women300 mcgper 2 Tablet(s)DSLD:15654
- NOWMulti-Food Complex Vcaps For Men300 mcgper 4 Vegetarian Capsule(s)DSLD:15658
- NOWMulti-Food Complex Vcaps For Women300 mcgper 4 Vegetarian Capsule(s)DSLD:15619
- NOWPrenatal Caps300 mcgper 4 Capsule(s)DSLD:15526
- NOWSpecial One100 mcgper 1 Tablet(s)DSLD:15678
- NOWStress Plus With Valerian Root300 mcgper 1 Tablet(s)DSLD:14175
- NOWStress Plus With Valerian Root300 mcgper 1 Tablet(s)DSLD:14177
- NOWSuperfruit Liquid Multi Acai Flavor100 mcgper 0.33 TbspDSLD:15366
- NOWVit-Min 100100 mcgper 1 Tablet(s)DSLD:15677
- NOWVit-Min 75+100 mcgper 1 Tablet(s)DSLD:15600
- NOWVit-Min 75+100 mcgper 1 Tablet(s)DSLD:15606
- NOWVit-Min 75+100 mcgper 1 Tablet(s)DSLD:15610
- NugenixNugenix Testosterone Multivitamin30 mcgper 2 Tablet(s)DSLD:178154
- NuMedicaPower Greens Premium Natural Berry90 mcgper 11.7 Gram(s)DSLD:182976
- Nutra SportMulti Vitamin200 mcgper 2 Capsule(s)DSLD:19282
- NutraBioMuscle Matrix MRP Women's Formula Chocolate Milkshake150 mcgper 22.29 Gram(s)DSLD:174729
- NutraBioReload Recovery Matrix Raw Unflavored200 mcgper 22.86 Gram(s)DSLD:174972
- Nutri-RichRadiance BoostD-Biotin · Biotin (Form: as D-Biotin)5,000 mcgper 3 Softgel(s)DSLD:176527
- Nutri-RichThe Essential Multi300 mcgper 1 Softgel(s)DSLD:176559
- NutriCologyEPD Basic MultiVitamin100 mcgper 2 Capsule(s)DSLD:184233
- NutriCologyMetabolic Co-Factor500 mcgper 6 Capsule(s)DSLD:193290
- NutriCologySuper Immuno Complex160 mcgper 1 Packet(s)DSLD:183928
- Nutrition NowB Complex Natural Strawberry Flavor75 mcgper 1 Gummy Vitamin(s)DSLD:176814
- OL Olympian LabsDaily Essentials Complete Formula300 mcgper 1 Tablet(s)DSLD:175957
- OL Olympian LabsDaily Essentials Women's Multi-Vitamin300 mcgper 1 Tablet(s)DSLD:175953
- OLLYThe Perfect Women's Multi Blissful BerryD-Biotin · Biotin (Form: as D-Biotin)375 mcgper 2 Gummie(s)DSLD:201750
- ON Optimum NutritionNatural Pro Complex Chocolate150 mcgper 80 Gram(s)DSLD:17580
- ON Optimum NutritionNatural Pro Complex Vanilla150 mcgper 77 Gram(s)DSLD:17577
- ON Optimum NutritionOpti-Men300 mcgper 3 Tablet(s)DSLD:17592
- ON Optimum NutritionOpti-Women250 mcgper 2 Capsule(s)DSLD:17617
- OneBodeEscalateD-Biotin · Biotin (Form: as D-Biotin)300 mcgper 1 Capsule(s)DSLD:12745
- Optimum NutritionAfter Max Chocolate Sunday58 mcgper 97 Gram(s)DSLD:17573
- Optimum NutritionAfter Max Vanilla Ice Cream58 mcgper 95 Gram(s)DSLD:17574
- Oregon HealthMulti-Guard300 mcgper 2 Capsule(s)DSLD:180726
- Oregon HealthMulti-Guard300 mcgper 2 Capsule(s)DSLD:180741
- OriginEasy To Swallow High Potency B Complex25 mcgper 1 Tablet(s)DSLD:12311
- Ortho Molecular ProductsAlpha Base Capsules with Iron200 mcgper 4 Capsule(s)DSLD:174158
- Ortho Molecular ProductsAlpha Base Capsules Without Iron200 mcgper 4 Capsule(s)DSLD:174163
- Ortho Molecular ProductsAlpha Base Capsules Without Iron200 mcgper 4 Capsule(s)DSLD:174168
- Ortho Molecular ProductsAlpha Base Capsules Without Iron200 mcgper 4 Capsule(s)DSLD:174209
- Ortho Molecular ProductsAlpha Base Capsules Without Iron200 mcgper 4 Capsule(s)DSLD:177705
- Ortho Molecular ProductsAlpha Base Capsules Without Iron200 mcgper 4 Capsule(s)DSLD:177779
- Ortho Molecular ProductsAlpha Base Premier Packs200 mcgper 1 Packet(s)DSLD:176591
- Ortho Molecular ProductsAlpha Base Premier Packs200 mcgper 1 Packet(s)DSLD:176632
- Ortho Molecular ProductsCandicid Forte300 mcgper 2 Capsule(s)DSLD:173999
- Ortho Molecular ProductsCandicid Forte300 mcgper 2 Capsule(s)DSLD:174001
- Ortho Molecular ProductsCosmedix500 mcgper 3 Capsule(s)DSLD:175146
- Ortho Molecular ProductsDiaxinolBiotin Note: USP3,000 mcgper 2 Capsule(s)DSLD:174478
- Ortho Molecular ProductsDiaxinolBiotin Note: USP3,000 mcgper 2 Capsule(s)DSLD:174483
- Ortho Molecular ProductsLipoic Acid 300 mg300 mcgper 1 Capsule(s)DSLD:173850
- Ortho Molecular ProductsMethyl B Complex75 mcgper 1 Capsule(s)DSLD:175118
- Ortho Molecular ProductsMitocore50 mcgper 2 Capsule(s)DSLD:174394
- Ortho Molecular ProductsMitocore50 mcgper 2 Capsule(s)DSLD:174406
- Ortho Molecular ProductsMucosagen250 mcgper 2 Capsule(s)DSLD:174488
- Ortho Molecular ProductsMucosagen250 mcgper 2 Capsule(s)DSLD:174498
- Ortho Molecular ProductsOrtho B Complex75 mcgper 1 Capsule(s)DSLD:173854
- Ortho Molecular ProductsOrtho B Complex75 mcgper 1 Capsule(s)DSLD:173792
- Ortho Molecular ProductsPrenatal Complete with DHA300 mcgper 3 Capsule(s)DSLD:175696
- P2LifeComplete Multivitamin300 mcgper 1 Tablet(s)DSLD:19149
- P2LifeSport Multi-Vitamin for Men450 mcgper 3 Capsule(s)DSLD:182804
- P2LifeSport Multi-Vitamin for Women450 mcgper 3 Capsule(s)DSLD:182960
- Pathway To HealingBasic Nutrient Support Tablet150 mcgper 5 Tablet(s)DSLD:14984
- Pathway To HealingBlood Sugar Support75 mcgper 2 Capsule(s)DSLD:14981
- PerqueBone Guard Forte 20 Tabsules250 mcgper 2 Capsule(s)DSLD:18701
- PerqueBone Guard Forte 20 Tabsules250 mcgper 2 Capsule(s)DSLD:18708
- PerqueLife Guard Mini TabsulesBiotin · Biotin (Form: as pure crystalline Biotin)250 mcgper 2 Tabsule(s)DSLD:18782
- PerqueLife Guard Mini TabsulesBiotin · Biotin (Form: as pure crystalline Biotin)250 mcgper 2 Tabsule(s)DSLD:18785
- PerqueLife Guard Tabsules Without PABA Or FolicinBiotin Note: pure crystalline500 mcgper 3 Tabsule(s)DSLD:18772
- Pfizer ProNutrientsSuper B-Complex + Antioxidants50 mcgper 1 Tablet(s)DSLD:19134
- PharmaFreakVita Freak Vf Packs100 mcgper 1 Packet(s)DSLD:19125
- plntWhole Food Kid's Chewable Multivitamin Natural Cherry Berry Mixed Flavor200 mcgper 2 Chewable Tablet(s)DSLD:181334
- plntWhole Food Men's Multivitamin300 mcgper 4 Vegetarian Capsule(s)DSLD:181329
- plntWhole Food Prenatal Multivitamin300 mcgper 3 Vegetarian Capsule(s)DSLD:181348
- plntWhole Food Women's 50+ Multivitamin300 mcgper 4 Vegetarian Capsule(s)DSLD:180654
- plntWhole Food Women's Multivitamin300 mcgper 4 Vegetarian Capsule(s)DSLD:180754
- Professional BotanicalsImmu Guardamount not statedper 1 Capsule(s)DSLD:199581
- Professional BotanicalsImmu Guardamount not statedper 1 Capsule(s)DSLD:199920
- Professional BotanicalsMeal Plex230 mcgper 27 Gram(s)DSLD:201681
- Professional BotanicalsUltimate Vita-Min120 mcgper 1 Capsule(s)DSLD:199572
- ProJoba InternationalProJoba Super Daily100 mcgper 3 Tablet(s)DSLD:12909
- Protocol For Life BalanceOrtho Multi For Men300 mcgper 2 Tablet(s)DSLD:11777
- Protocol For Life BalanceOrtho Multi For Women300 mcgper 3 Vegetarian Capsule(s)DSLD:11791
- Protocol For Life BalanceOrtho Multi For Women300 mcgper 3 Tablet(s)DSLD:11810
- Protocol For Life BalanceOrtho Multi For Women300 mcgper 3 Vegetarian Capsule(s)DSLD:15510
- Protocol For Life BalanceOrtho Multi Super Fruits Acai Flavor100 mcgper 0.33 TbspDSLD:15408
- Protocol For Life BalanceProtoClear BerryD-Biotin · Biotin (Form: as D-Biotin)75 mcgper 25 Gram(s)DSLD:201335
- Protocol For Life BalanceProtoClear ChocolateD-Biotin · Biotin (Form: as D-Biotin)75 mcgper 27 Gram(s)DSLD:200420
- Protocol For Life BalanceProtoClear Detoxification FormulaD-Biotin · Biotin (Form: as D-Biotin)150 mcgper 27.5 Gram(s)DSLD:11708
- Protocol For Life BalanceProtoClear Natural Orange FlavorD-Biotin · Biotin (Form: as D-Biotin)150 mcgper 55 Gram(s)DSLD:11725
- Protocol For Life BalanceProtoClear VanillaD-Biotin · Biotin (Form: as D-Biotin)75 mcgper 25 Gram(s)DSLD:201340
- Protocol For Life BalanceProtoMeal Natural Berry FlavorD-Biotin · Biotin (Form: as D-Biotin)300 mcgper 50 Gram(s)DSLD:15429
- PS ProSuppsKarbolic Super-Premium Muscle Fuel Orange Burst300 mcgper 31.25 Gram(s)DSLD:17714
- PS ProSuppsKarbolic Super-Premium Muscle Fuel Power Punch300 mcgper 31.25 Gram(s)DSLD:17708
- PS ProSuppsKarbolic Super-Premium Muscle Fuel Strawberry Popsicle300 mcgper 31.25 Gram(s)DSLD:17707
- PS ProSuppsKarbolic Super-Premium Muscle Fuel Strawberry Popsicle300 mcgper 31.25 Gram(s)DSLD:17716
- Pure AdvantageMRP Chocolate88 mcgper 69 Gram(s)DSLD:180795
- Pure AdvantageMRP Vanilla88 mcgper 69 Gram(s)DSLD:180822
- Pure EncapsulationsAthletic Nutrients266 mcgper 2 Capsule(s)DSLD:184296
- Pure EncapsulationsAthletic Pure Pack400 mcgper 9 Capsule(s)DSLD:182730
- Pure EncapsulationsB-Complex Plus400 mcgper 1 Capsule(s)DSLD:204418
- Pure EncapsulationsEnergize Plus Pure Pack400 mcgper 7 Capsule(s)DSLD:184817
- Pure EncapsulationsLiquiNutrients Natural Lemon Creme Flavor400 mcgper 2 tspDSLD:184821
- Pure EncapsulationsMen's Pure Pack400 mcgper 8 Capsule(s)DSLD:183007
- Pure EncapsulationsPureFood NutrientsSaccharomyces cerevisiae · Biotin (Form: from Saccharomyces cerevisae Genus: Saccharomyces Species: cerevisae)300 mcgper 4 Capsule(s)DSLD:184827
- Pure EncapsulationsPureLean (with Stevia) Natural Vanilla Bean Flavor150 mcgper 27 Gram(s)DSLD:188777
- Pure EncapsulationsPureLean Natural Chocolate Flavor150 mcgper 37 Gram(s)DSLD:185315
- Pure EncapsulationsPureLean Natural Vanilla Bean Flavor150 mcgper 34 Gram(s)DSLD:188758
- Pure EncapsulationsPureLean Pure Pack1.5 mgper 7 Capsule(s)DSLD:188790
- Pure EncapsulationsPureLean Ultra Natural Vanilla Bean Flavor3,000 mcgper 45.8 Gram(s)DSLD:187494
- Pure EncapsulationsWomen's Pure Pack1 mcgper 9 Capsule(s)DSLD:183301
- Pure KidzLiquid Multi Vitamin Great Tasting Cherry Flavor300 mcgper 1 TbspDSLD:180851
- Pure VeganAdvanced Vegan300 mcgper 2 Capsule(s)DSLD:180382
- Pure VeganVegan Complete Vanilla150 mcgper 43 Gram(s)DSLD:180409
- RadianceSoy Protein Isolate Powder Delicious Vanilla60 mcgper 30 Gram(s)DSLD:193360
- RealDoseRealMeal GF Natural Chocolate Flavor100 mcgper 31.4 Gram(s)DSLD:182109
- RealDoseRealMeal GF Natural Vanilla Flavor100 mcgper 34.8 Gram(s)DSLD:182865
- RelivClassic300 mcgper 17.9 Gram(s)DSLD:201244
- RelivFit3 Active Vanilla Kick Natural Flavor75 mcgper 18.35 Gram(s)DSLD:178495
- RelivNow For Kids Chocolate150 mcgper 29 Gram(s)DSLD:178949
- RelivNow For Kids Vanilla150 mcgper 29 Gram(s)DSLD:178955
- RelivNow with Luna Rich300 mcgper 18.76 Gram(s)DSLD:201254
- RelivNow with Whey300 mcgper 18.65 Gram(s)DSLD:201257
- Renew LifeSkinny Gut Ultimate Shake Natural Chocolate Flavor90 mcgper 41 Gram(s)DSLD:178306
- RidgeCrest HerbalsHair ReVive6,000 mcgper 4 Capsule(s)DSLD:177327
- RisingNail-Ex Biotin 2.5 mg2,500 mcgper 1 Tablet(s)DSLD:15741
- Rite Aid PharmacyOne Daily Women's with Vitamin D-330 mcgper 1 Tablet(s)DSLD:181440
- Rite Aid PharmacyOne Daily Women's with Vitamin D-3300 mcgper 1 Tablet(s)DSLD:181542
- RivalusRivalmen300 mcgper 3 Tablet(s)DSLD:182210
- RugbyBee Zee300 mcgper 1 Tablet(s)DSLD:200943
- RugbyBiotin 300 mcg300 mcgper 1 Tablet(s)DSLD:200850
- RugbyCerovite Jr.45 mcgper 0.5 Tablet(s)DSLD:200823
- RugbyCerovite Liquid300 mcgper 1 TbspDSLD:14446
- RugbyChildren's Chewable Vite with Iron40 mcgper 0.5 Tablet(s)DSLD:201197
- RugbyNephro-Vite Vitamin B and C Complex300 mcgper 1 Tablet(s)DSLD:200842
- RugbyTherems30 mcgper 1 Tablet(s)DSLD:200518
- RugbyTherems30 mcgper 1 Tablet(s)DSLD:200521
- RugbyTherems-M30 mcgper 1 Tablet(s)DSLD:200831
- RugbyVi-Stress45 mcgper 1 Tablet(s)DSLD:14530
- Safeway CareCentury Senior 50+ Formula30 mcgper 1 Tablet(s)DSLD:12216
- Safeway CareOne Daily Women's Formula30 mcgper 1 Tablet(s)DSLD:12207
- SANDr. Feel Good!300 mcgper 4 Tablet(s)DSLD:175350
- SANDr. Feel Good!300 mcgper 4 Tablet(s)DSLD:175365
- SANDr. Feel Good!300 mcgper 4 Tablet(s)DSLD:175369
- Scientific Nutrition For Advanced Conditioning SNACMulti-Vitamins Only300 mcgper 1 Capsule(s)DSLD:14634
- Scientific Nutrition For Advanced Conditioning SNACPED Performance Energy Drink Raspberry Lemonade200 mcgper 9.2 Gram(s)DSLD:14627
- Seeking HealthOptimal Multivitamin W/ IronBiotin Note: USP600 mcgper 4 Capsule(s)DSLD:174726
- Seeking HealthOptimal Prenatal Chocolate500 mcgper 43.2 Gram(s)DSLD:174745
- Seeking HealthOptimal Prenatal Vanilla500 mcgper 36.4 Gram(s)DSLD:174748
- Sequel VegaComplete Whole Food Health Optimizer Berry Flavor30 mcgper 69 Gram(s)DSLD:18355
- Sequel VegaComplete Whole Food Health Optimizer Berry Flavor300 mcgper 69 Gram(s)DSLD:18356
- Sequel VegaComplete Whole Food Health Optimizer Natural Flavor30 mcgper 61 Gram(s)DSLD:18351
- Sequel VegaComplete Whole Food Health Optimizer Vanilla Chai Flavor30 mcgper 65 Gram(s)DSLD:18357
- ShakleeVita-Lea Gold without Vitamin K FormulaD-Biotin · Biotin (Form: as D-Biotin)300 mcgper 2 Tablet(s)DSLD:17529
- ShakleeVita-Lea Iron FormulaD-Biotin · Biotin (Form: as D-Biotin)300 mcgper 2 Tablet(s)DSLD:17515
- ShakleeVita-Lea without Iron FormulaD-Biotin · Biotin (Form: as D-Biotin)300 mcgper 2 Tablet(s)DSLD:17500
- ShakleeVitalizerD-Biotin · Biotin (Form: as D-Biotin)300 mcgper 1 Strip(s)DSLD:17332
- Smart SenseCentury Adult30 mcgper 1 Tablet(s)DSLD:175041
- Smart SenseCentury Mature30 mcgper 1 Tablet(s)DSLD:175031
- SolgarB-Complex "100"D-Biotin · Biotin (Form: as D-Biotin)100 mcgper 1 Vegetable Capsule(s)DSLD:201215
- SolgarB-Complex "100"D-Biotin · Biotin (Form: as D-Biotin)100 mcgper 1 Tablet(s)DSLD:201217
- SolgarB-Complex with Vitamin C Stress FormulaD-Biotin · Biotin (Form: as D-Biotin)25 mcgper 2 Tablet(s)DSLD:200564
- SolgarB-Complex with Vitamin C Stress FormulaD-Biotin · Biotin (Form: as D-Biotin)25 mcgper 2 Tablet(s)DSLD:200572
- SolgarMale MultipleD-Biotin · Biotin (Form: as D-Biotin)300 mcgper 3 Tablet(s)DSLD:201405
- SolgarMale MultipleD-Biotin · Biotin (Form: as D-Biotin)300 mcgper 3 Tablet(s)DSLD:201420
- SolgarOmnium Iron-FreeD-Biotin · Biotin (Form: as D-Biotin)100 mcgper 2 Tablet(s)DSLD:201577
- SolgarSuper Potency Biotin 5000 mcg5,000 mcgper 1 Vegetable Capsule(s)DSLD:200885
- SolgarSuper Potency Biotin 5000 mcg5,000 mcgper 1 Vegetable Capsule(s)DSLD:200888
- SolgarUltimate B+C ComplexD-Biotin · Biotin (Form: as D-Biotin)50 mcgper 1 Tablet(s)DSLD:201646
- SolgarVitamins Only50 mcgper 1 Vegetable Capsule(s)DSLD:181511
- Sonoran BloomWellavoh Daily Multi-Nutrient Complex For Women AM Formula300 mcgper 3 Softgel(s)DSLD:11623
- Sonoran BloomWellavoh Daily Multi-Nutrient Complex For Women PM Formula300 mcgper 3 Softgel(s)DSLD:11630
- Source NaturalsAdvanced One Multiple300 mcgper 1 Tablet(s)DSLD:181591
- Source NaturalsAdvanced One Multiple300 mcgper 1 Tablet(s)DSLD:181628
- Source NaturalsAdvanced One Multiple300 mcgper 1 Tablet(s)DSLD:181630
- Source NaturalsAdvanced One Multiple300 mcgper 1 Tablet(s)DSLD:181633
- Source NaturalsAdvanced One Multiple300 mcgper 1 Tablet(s)DSLD:181634
- Source NaturalsAdvanced One Multiple300 mcgper 1 Tablet(s)DSLD:181635
- Source NaturalsBiotin 10,000 mcg10,000 mcgper 1 Tablet(s)DSLD:186336
- Source NaturalsBiotin 600 mcg600 mcgper 1 Tablet(s)DSLD:185256
- Spring ValleyBiotin 10,000 mcgD-Biotin · Biotin (Form: as D-Biotin)10,000 mcgper 1 Softgel(s)DSLD:178538
- Spring ValleyBiotin 1000 mcgD-Biotin · Biotin (Form: as D-Biotin)1,000 mcgper 1 Softgel(s)DSLD:184057
- Spring ValleyBiotin 5,000 mcgD-Biotin · Biotin (Form: as D-Biotin)5,000 mcgper 1 Softgel(s)DSLD:178534
- Spring ValleyBiotin 5,000 mcgD-Biotin · Biotin (Form: as D-Biotin)5,000 mcgper 1 Softgel(s)DSLD:178536
- Spring ValleyChildren's Multivitamin Gummiesamount not statedper 1 Gummy(ies)DSLD:178559
- Spring ValleyDiabetes Daily Pack30 mcgper 1 Packet(s)DSLD:178643
- Spring ValleyMen's MultivitaminD-Biotin · Biotin (Form: as D-Biotin)300 mcgper 2 Tablet(s)DSLD:178316
- Spring ValleyMen's MultivitaminD-Biotin · Biotin (Form: as D-Biotin)300 mcgper 2 Tablet(s)DSLD:178383
- Spring ValleyNatural Super B-Complex45 mcgper 1 Tablet(s)DSLD:19059
- Spring ValleyNatural Super B-Complex45 mcgper 1 Tablet(s)DSLD:19061
- Spring ValleyNatural Super B-Complex45 mcgper 1 Tablet(s)DSLD:19064
- Spring ValleyOrganic Multivitamin Real Fruit Gummies300 mcgper 2 Gummie(s)DSLD:178710
- Spring ValleyWomen's MultivitaminD-Biotin · Biotin (Form: as D-Biotin)300 mcgper 2 Tablet(s)DSLD:178361
- Spring ValleyWomen's MultivitaminD-Biotin · Biotin (Form: as D-Biotin)300 mcgper 2 Tablet(s)DSLD:178398
- Spring ValleyWomen's MultivitaminD-Biotin · Biotin (Form: as D-Biotin)300 mcgper 2 Tablet(s)DSLD:178791
- SundownMarvel The Amazing Spider-Man Complete20 mcgper 0.5 Tablet(s)DSLD:197373
- Sundown NaturalsB100 ComplexD-Biotin · Biotin (Form: as D-Biotin)100 mcgper 1 Caplet(s)DSLD:1100
- Sundown NaturalsBiotin 7500 mcgD-Biotin · Biotin (Form: as D-Biotin)7,500 mcgper 1 Tablet(s)DSLD:175102
- Sundown NaturalsIron Free Daily Multiple 50+D-Biotin · Biotin (Form: as D-Biotin)30 mcgper 1 Caplet(s)DSLD:1094
- Sundown NaturalsMultivitamin GummiesD-Biotin · Biotin (Form: as D-Biotin)300 mcgper 2 Gummy(ies)DSLD:174988
- SunmarkAnimal Shapes Complete With Choline20 mcgper 0.5 Tablet(s)DSLD:10008
- SunmarkComplete Advanced Formula USP30 mcgper 1 Tablet(s)DSLD:12168
- SunriderMetabalance 4433.1 mcgper 2 Capsule(s)DSLD:12150
- SunwarriorIllumin8 Aztec Chocolate15 mcgper 40 Gram(s)DSLD:200387
- SunwarriorIllumin8 Mocha15 mcgper 40 Gram(s)DSLD:200543
- SunwarriorIllumin8 Vanilla Bean15 mcgper 40 Gram(s)DSLD:200546
- Superior SourceBalance B Complex600 mcgper 2 Tablet(s)DSLD:12138
- SwansonActivated B-Complex High Potency and Bioavailability50 mcgper 1 Veggie Capsule(s)DSLD:189920
- SwansonB-125 Complex High Potency Formula125 mcgper 1 Tablet(s)DSLD:203209
- SwansonBalance B-100 Complex High PotencyBiotin Note: USP100 mcgper 1 Capsule(s)DSLD:202291
- SwansonBalance B-100 Complex High-PotencyBiotin Note: USP100 mcgper 1 Capsule(s)DSLD:202292
- SwansonBalance B-200 Complex Higher-PotencyD-Biotin · Biotin (Form: as D-Biotin)600 mcgper 1 Veggie Capsule(s)DSLD:203173
- SwansonBalance B-50 Complex50 mcgper 1 Capsule(s)DSLD:202295
- SwansonBiotin 10,000 mcg High Potency10,000 mcgper 1 Softgel(s)DSLD:203207
- SwansonCholesterol EssentialsBiotin Note: USP6 mcgper 2 Tablet(s)DSLD:203265
- SwansonMulti with Iron Century Formula25 mcgper 1 Tablet(s)DSLD:187463
- SwansonMulti without Minerals300 mcgper 1 Veggie Capsule(s)DSLD:203165
- SwansonMulti Women's Prime5 mcgper 1 Tablet(s)DSLD:202791
- SwansonReal Food Biotin 5,000 mcgCertified organic Orgen-Bio Sesbania extract · Biotin (Form: from Certified organic Orgen-Bio Sesbania extract PlantPart: leaf Genus: Sesbania Species: grandiflora)5,000 mcgper 2 Veggie Capsule(s)DSLD:191098
- SwansonReal Food Multi Men's DailyPANMOL B-COMPLEX · Biotin (Form: from PANMOL B-COMPLEX (Form: from Quinoa PlantPart: sprouts))150 mcgper 3 Veggie Capsule(s)DSLD:181861
- SwansonReal Food Multi Women's DailyPANMOL B-COMPLEX · Biotin (Form: from PANMOL B-COMPLEX (Form: from Quinoa PlantPart: sprouts))150 mcgper 3 Veggie Capsule(s)DSLD:182009
- Terry NaturallyClinical EssentialsD-Biotin · Biotin (Form: as D-Biotin)250 mcgper 2 Tablet(s)DSLD:202399
- Terry NaturallyHealthy Feet & Nerves1,000 mcgper 2 Capsule(s)DSLD:202675
- Terry NaturallyHealthy Feet & Nerves1,000 mcgper 2 Capsule(s)DSLD:202703
- The Isopure CompanyIsopoure Low Carb Dutch Chocolate75 mcgper 33 Gram(s)DSLD:173793
- The Isopure CompanyIsopure Low Carb Dutch Chocolate75 mcgper 33 Gram(s)DSLD:173825
- The Isopure CompanyIsopure Low Carb Dutch Chocolate75 mcgper 33 Gram(s)DSLD:173873
- The Isopure CompanyIsopure Low Carb Dutch Chocolate75 mcgper 33 Gram(s)DSLD:173881
- The Isopure CompanyIsopure Zero Carb Creamy Vanilla75 mcgper 31 Gram(s)DSLD:173841
- The Isopure CompanyIsopure Zero Carb Creamy Vanilla75 mcgper 31 Gram(s)DSLD:173797
- The Isopure CompanyIsopure Zero Carb Creamy Vanilla75 mcgper 31 Gram(s)DSLD:173878
- The Isopure CompanyIsopure Zero Carb Creamy Vanilla75 mcgper 31 Gram(s)DSLD:173886
- The Isopure CompanyIsopure Zero Carb Protein Powder Cookies & Cream75 mcgper 31 Gram(s)DSLD:176458
- The Isopure CompanyIsopure Zero Carb Protein Powder Cookies & Cream75 mcgper 31 Gram(s)DSLD:176466
- The Isopure CompanyIsopure Zero Carb Toasted Coconut75 mcgper 32 Gram(s)DSLD:173831
- The Vitamin ShoppeAlpha Lipoic Acid with Chromax & Biotin 300 mgD-Biotin · Biotin (Form: as D-Biotin)100 mcgper 1 Capsule(s)DSLD:183848
- The Vitamin ShoppeBiotin 5 mg5 mgper 1 Capsule(s)DSLD:13132
- The Vitamin ShoppeBiotin 500 mcg500 mcgper 1 Capsule(s)DSLD:183700
- The Vitamin ShoppeBiotin 500 mcg500 mcgper 1 Veggie Capsule(s)DSLD:184048
- The Vitamin ShoppeLiquid Multi Orange Vanilla Flavor300 mcgper 1 oz.DSLD:13175
- The Vitamin ShoppeMen's Gummy Multivitamins30 mcgper 2 Gummy(ies)DSLD:204463
- The Vitamin ShoppeOne Daily Women'sD-Biotin · Biotin (Form: as D-Biotin)600 mcgper 1 Tablet(s)DSLD:204131
- The Vitamin ShoppeOne Daily Women'sD-Biotin · Biotin (Form: as D-Biotin)600 mcgper 1 Tablet(s)DSLD:204678
- The Vitamin ShoppeOne Daily Women's No IronD-Biotin · Biotin (Form: as D-Biotin)600 mcgper 1 Tablet(s)DSLD:204144
- The Vitamin ShoppeStress Formula300 mcgper 3 Tablet(s)DSLD:180500
- The Vitamin ShoppeUltimate ManD-Biotin · Biotin (Form: as D-Biotin)300 mcgper 2 Tablet(s)DSLD:203634
- The Vitamin ShoppeUltimate ManD-Biotin · Biotin (Form: as D-Biotin)300 mcgper 2 Tablet(s)DSLD:203641
- The Vitamin ShoppeUltimate Man GoldD-Biotin · Biotin (Form: as D-Biotin)600 mcgper 3 Tablet(s)DSLD:204494
- The Vitamin ShoppeUltimate Man GoldD-Biotin · Biotin (Form: as D-Biotin)600 mcgper 3 Tablet(s)DSLD:204508
- The Vitamin ShoppeUltimate Woman 50+D-Biotin · Biotin (Form: as D-Biotin)600 mcgper 3 Tablet(s)DSLD:203515
- The Vitamin ShoppeUltimate Woman GoldD-Biotin · Biotin (Form: as D-Biotin)600 mcgper 3 Tablet(s)DSLD:204324
- The Vitamin ShoppeUltimate Woman GoldD-Biotin · Biotin (Form: as D-Biotin)600 mcgper 3 Tablet(s)DSLD:204329
- The Vitamin ShoppeUltimate Woman No IronD-Biotin · Biotin (Form: as D-Biotin)300 mcgper 2 Tablet(s)DSLD:204124
- The Vitamin ShoppeWomen's Gummy Multivitamins400 mcgper 2 Gummy(ies)DSLD:204470
- The Vitamin ShoppeYeast Fend900 mcgper 3 Capsule(s)DSLD:184055
- Thera-ZymeVSCLR10 mcgper 2 Capsule(s)DSLD:177109
- Thera-ZymeVSCLR10 mcgper 2 Capsule(s)DSLD:177111
- Tokkyo NutritionProtein 100% Whey Chocolateamount not statedper 30 Gram(s)DSLD:180565
- Tokkyo NutritionTokkyo Protein Cookies & Creamamount not statedper 30 Gram(s)DSLD:19862
- Tokkyo NutritionTokkyo Protein Strawberryamount not statedper 30 Gram(s)DSLD:19861
- Tokkyo NutritionTokkyo Protein Vanillaamount not statedper 30 Gram(s)DSLD:19859
- Top CareCentury Ultimate Men's40 mcgper 1 Tablet(s)DSLD:12115
- Top CareOne Daily Men's Formula30 mcgper 1 Tablet(s)DSLD:12113
- Top SecretN.O.370 Pre-Workout Formula Fruit Punch600 mcgper 10 Gram(s)DSLD:17548
- Trader Joe'sGummi Vites66 mcgper 1 Gummy(ies)DSLD:174232
- Trader Joe'sHigh Potency Multiple Vitamin & MineralD-Biotin · Biotin (Form: as D-Biotin)25 mcgper 2 Tablet(s)DSLD:174087
- Trader Joe'sWomen's High Potency Multiple Vitamin & MineralD-Biotin · Biotin (Form: as D-Biotin)60 mcgper 2 Tablet(s)DSLD:174178
- TriVitaGlucoManage FormulaD-Biotin · Biotin (Form: as D-Biotin)2 mgper 1 Capsule(s)DSLD:16268
- TriVitaHCY Guard25 mcgper 1 Tablet(s)DSLD:16273
- TriVitaLeanology1,000 mcgper 3 Capsule(s)DSLD:11516
- TriVitaNerve FormulaD-Biotin · Biotin (Form: as D-Biotin)1,000 mcgper 1 Capsule(s)DSLD:11495
- TriVitaPeaceful Sleep1,000 mcgper 2 Capsule(s)DSLD:16267
- True HealthDr. Cutler's Ultimate Blood Sugar Formula9,000 mcgper 1 Capsule(s)DSLD:16731
- True HealthDr. Cutler's Ultimate Multi-Complete300 mcgper 2 Capsule(s)DSLD:16779
- TwinlabBariatric Support Basic Essentials Chocolate52.5 mcgper 28 Gram(s)DSLD:17036
- TwinlabBariatric Support Basic Essentials Vanilla52.5 mcgper 28 Gram(s)DSLD:17032
- TwinlabBariatric Support Super B Complex Cherry Flavor50 mcgper 1 tspDSLD:12557
- Ultra PlanUltimate-Plus300 mcgper 3 Tablet(s)DSLD:12951
- up&upAdult's Gummy Multivitamin15 mcgper 2 Gummy(ies)DSLD:19911
- up&upAdult's Gummy Multivitamin/Multimineral150 mcgper 2 Gummy(ies)DSLD:19914
- up&upAdult's Gummy Multivitamins15 mcgper 2 Gummy(ies)DSLD:19920
- up&upAdults' 50+ Multivitamin/Multimineral30 mcgper 1 Tablet(s)DSLD:19916
- up&upBiotin 1,000 mcgD-Biotin · Biotin (Form: as D-Biotin)1,000 mcgper 1 Tablet(s)DSLD:19991
- up&upBiotin 5,000 mcgD-Biotin · Biotin (Form: as D-Biotin)5,000 mcgper 1 Capsule(s)DSLD:19975
- up&upChildren's Gummy Multivitamin60 mcgper 1 Gummy(ies)DSLD:19926
- up&upChildren's Gummy Multivitamin with Choline75 mcgper 1 Gummy(ies)DSLD:19923
- up&upChildren's Multivitamin20 mcgper 0.5 Tablet(s)DSLD:19828
- up&upMen's Daily Multivitamin30 mcgper 1 Tablet(s)DSLD:19900
- up&upMen's Daily Multivitamin30 mcgper 1 Tablet(s)DSLD:19907
- up&upMultivitamin Men's 50+ Advanced30 mcgper 1 Tablet(s)DSLD:20181
- up&upMultivitamin Women's 50+ Advanced30 mcgper 1 Tablet(s)DSLD:12051
- up&upMultivitamin Women's 50+ Advanced30 mcgper 1 Tablet(s)DSLD:19897
- up&upMultivitamin/Multimineral Adults Under 5030 mcgper 1 Tablet(s)DSLD:19868
- up&upMultivitamin/Multimineral Adults Under 5030 mcgper 1 Tablet(s)DSLD:19910
- up&upTeen for Her Advanced300 mcgper 1 Tablet(s)DSLD:12081
- up&upVitamin B Complex50 mcgper 1 Tablet(s)DSLD:20200
- up&upWomen's Daily Active Metabolism30 mcgper 1 Tablet(s)DSLD:19854
- up&upWomen's Daily Multivitamin30 mcgper 1 Tablet(s)DSLD:19852
- up&upWomen's Daily Multivitamin30 mcgper 1 Tablet(s)DSLD:19853
- up&upWomen's Multivitamin/Multimineral30 mcgper 1 Tablet(s)DSLD:12052
- VegaOne All-In-One Nutritional Shake Berry15 mcgper 42.5 Gram(s)DSLD:14856
- VegaOne All-In-One Nutritional Shake Berry15 mcgper 42.5 Gram(s)DSLD:14861
- VegaOne All-In-One Nutritional Shake Chocolate15 mcgper 10.95 Gram(s)DSLD:18359
- VegaOne All-In-One Nutritional Shake Natural15 mcgper 8.975 Gram(s)DSLD:18362
- VegaOne All-In-One Nutritional Shake Vanilla Chai15 mcgper 9.925 Gram(s)DSLD:18364
- ViandaAvlimil Multi1,000 mcgper 2 Capsule(s)DSLD:176260
- ViandaPavaxin60 mcgper 2 Tablet(s)DSLD:176361
- Vibrant HealthSuper Kids Vibrance Awesome AppleBiotin Note: from plants20 mcgper 6.6 Gram(s)DSLD:183893
- Vibrant HealthTrilogy WomenBiotin Note: from plants30 mcgper 1 Packet(s)DSLD:184335
- Virtus PharmaceuticalsPNV Tabs 29-130 mcgper 1 Tablet(s)DSLD:180567
- Virtus PharmaceuticalsVirt-Caps150 mcgper 1 Softgel(s)DSLD:180515
- Virtus PharmaceuticalsVirt-PN300 mcgper 1 Tablet(s)DSLD:180521
- Virtus PharmaceuticalsVirt-PN Plus250 mcgper 1 Softgel(s)DSLD:180537
- vitafusionB Complex Energy Wild Strawberry75 mcgper 1 Gummy(ies)DSLD:12930
- vitafusionB Complex Natural Strawberry Flavor75 mcgper 1 Gummy Vitamin(s)DSLD:174855
- vitafusionB Complex Natural Strawberry Flavor75 mcgper 1 Gummy Vitamin(s)DSLD:176822
- vitafusionComplete Multivitamin Natural Blackberry Flavor15 mcgper 2 Gummy Vitamin(s)DSLD:177200
- vitafusionPlatinum 50+ Natural Peach Flavor30 mcgper 2 Gummy Vitamin(s)DSLD:177046
- vitafusionWomen's Complete MultiVitamin Formula300 mcgper 2 Gummy(ies)DSLD:12933
- Vitamin WorldBiotin 300 mcg300 mcgper 1 Tablet(s)DSLD:1200
- Vitamin WorldFantastic Kids Gummies MultiVitamin45 mcgper 2 Gummy(ies)DSLD:1829
- Vitamin WorldFocus Complex With Neuro-PSD-Biotin · Biotin (Form: as D-Biotin)300 mcgper 4 Caplet(s)DSLD:20278
- Vitamin WorldMega B-100 Timed ReleaseD-Biotin · Biotin (Form: as d-Biotin)100 mcgper 1 Caplet(s)DSLD:1201
- Vitamin WorldMega B-50D-Biotin · Biotin (Form: as D-Biotin)50 mcgper 1 Capsule(s)DSLD:1820
- Vitamin WorldSoy Protein Isolate Powder Unflavoredamount not statedper 28 Gram(s)DSLD:20440
- Vitamin WorldTheanine Calm Caps500 mcgper 2 Capsule(s)DSLD:1295
- Vitamin WorldUltra Biotin 7500 mcgD-Biotin · Biotin (Form: as D-Biotin)7,500 mcgper 1 Tablet(s)DSLD:1486
- Vitamin WorldUltra Biotin 7500 mcgD-Biotin · Biotin (Form: as D-Biotin)7,500 mcgper 1 Tablet(s)DSLD:1487
- Vitamin WorldUltra Man Hair Formula2,000 mcgper 3 Caplet(s)DSLD:1854
- Vitamin WorldVitamins For The Hair2,000 mcgper 3 Caplet(s)DSLD:1197
- VitolRussian Bear300 mcgper 8 Tablet(s)DSLD:18005
- Viva VitaminsBe Calm Extra Strength160 mcgper 1 Tablet(s)DSLD:1795
- Viva VitaminsBe Calm Regular Strength80 mcgper 1 Tablet(s)DSLD:1787
- Viva VitaminsBe Calm Regular Strength80 mcgper 1 Tablet(s)DSLD:1788
- Viva VitaminsComplete Multi Regular Strength - Timed Release500 mcgper 4 Tablet(s)DSLD:19935
- Viva VitaminsComplete Multi Ultra Strength100 mcgper 1 Tablet(s)DSLD:19997
- Viva VitaminsV.M.T. Extra Strength70 mcgper 3 Tablet(s)DSLD:1753
- Viva VitaminsV.M.T. Regular Strength35 mcgper 3 Tablet(s)DSLD:1752
- Viva VitaminsVegiSource Multivitamin40 mcgper 3 Tablet(s)DSLD:20021
- Viva Vitamins Be Calm Extra Strength160 mcgper 1 Tablet(s)DSLD:1780
- WalgreensA Thru Z Active Performance50 mcgper 1 Tablet(s)DSLD:12931
- WalgreensAdvanced Formula A Thru Z30 mcgper 1 Tablet(s)DSLD:12922
- WalgreensChildren's Gummies75 mcgper 1 Gummy(ies)DSLD:12938
- Whole FoodsB Daily Essentials300 mcgper 1 Capsule(s)DSLD:12021
- Wicked Fast Sports NutritionIntense DefenseD-Biotin · Biotin (Form: as D-Biotin)300 mcgper 6 Tablet(s)DSLD:191129
- WindmillBiotin 300 mcg300 mcgper 1 Tablet(s)DSLD:180874
- Women to WomenEssential Nutrients and Omega-3100 mcgper 1 Packet(s)DSLD:12915
- XtendlifeDiabet-Eze2,992 mcgper 6 Tablet(s)DSLD:17016
- XtendlifeNeuro-Natural Memory1,994 mcgper 2 Tablet(s)DSLD:17031
- YuhanDabotamin Q Tab.100 ugper 1 Tablet(s)DSLD:12908
- Yum-V'sMulti Vitamin + Mineral Formula Yummy Grape Flavor12 mcgper 2 Gummy(ies)DSLD:17775
Label record: NIH Office of Dietary Supplements · CC0
Where it reaches
8 systems, 14 regions, 24 tissues, 24 transporter routes — routes, not measurements: transporters known to carry biotin are expressed there, and no source reports it arriving.
Loading the model…
Papers screened
119 papers
- Compound
- biotin
- Screened
- 119
- Admitted
- 3
- Discarded
- 107
- Not read
- 9
Produced a finding3 papers
- PMID:166777982026-10-23
- PMID:343324612026-10-23
- PMID:275890592026-10-12
Discarded: the wrong intervention61 papers
- PMID:11975567cited by PMID:21761519; not about the subject it would be filed under2026-10-25
- PMID:15330631cited by PMID:21761519; not about the subject it would be filed under2026-10-25
- PMID:15548086cited by PMID:21761519; not about the subject it would be filed under2026-10-25
- PMID:16407987cited by PMID:21761519; not about the subject it would be filed under2026-10-25
- PMID:17175580cited by PMID:21761519; not about the subject it would be filed under2026-10-25
- PMID:17406607cited by PMID:21761519; not about the subject it would be filed under2026-10-25
- PMID:17942682cited by PMID:21761519; not about the subject it would be filed under2026-10-25
- PMID:18272492cited by PMID:21761519; not about the subject it would be filed under2026-10-25
- PMID:18451302cited by PMID:21761519; not about the subject it would be filed under2026-10-25
- PMID:19104067cited by PMID:21761519; not about the subject it would be filed under2026-10-25
- PMID:19714693cited by PMID:21761519; not about the subject it would be filed under2026-10-25
- PMID:20080615cited by PMID:21761519; not about the subject it would be filed under2026-10-25
and 49 more.
Discarded: another reason, stated per paper21 papers
- PMID:21761519no claim extracted — cause not determined2026-10-25
- PMID:9015339no claim extracted — subject_absent — DOSED: Abstract never mentions biotin; it is about vestibular compensation, Fos expression and flocculectomy in rats | Paper is about vestibular compensation in rats (labyrinthectomy, flocculectomy, retrograde tracing); abstract never mentions biotin2026-10-25
- PMID:7726384no claim extracted — cause not determined (one pass only) — measured: maintenance of normal neurologic function (unscored, narrative) in biotinidase, holocarboxylase synthetase deficiency and Leigh encephalopathy2026-10-23
- PMID:26715368no claim extracted — cause not determined2026-10-23
- PMID:28222020no claim extracted — cause not determined (one pass only) — measured: analytical interference of high-dose biotin on streptavidin-biotin hormone immunoassays, results before versus after N5 biotin removal2026-10-23
- PMID:17186472no claim extracted — subject_absent — DOSED: Paper is about coenzyme Q10 deficiency and PDSS2 mutations in an infant with Leigh syndrome; biotin is never mentioned | Nothing dosed; paper is a case description of PDSS2 mutations and coenzyme Q10 deficiency in an infant with Leigh syndrome. Biotin is not mentioned.2026-10-23
- PMID:32445355no claim extracted — cause not determined2026-10-23
- NCT00731588design×1 — allocation NON_RANDOMIZED -- not randomised2026-10-13
- NCT01204216design×1 — allocation NON_RANDOMIZED -- not randomised2026-10-13
- NCT01474486design×1 — allocation NA -- not randomised2026-10-13
- NCT02757898design×1 — allocation NA -- not randomised2026-10-13
- NCT02967679design×1 — allocation NA -- not randomised2026-10-13
and 9 more.
Discarded: an endpoint this vocabulary does not hold16 papers
- PMID:8232780no claim extracted — no_outcome_node — measured: cerebral atrophy on serial CT-scan and MRI brain imaging, two-patient case report | brain atrophy on serial CT/MRI imaging (case report)2026-10-25
- PMID:8352834no claim extracted — no_outcome_node — measured: flash-evoked visual potentials, neuro-ophthalmological and motor deficit recovery in a single-patient case report | flash-evoked visual potentials, neurophysiological recording (single case)2026-10-25
- PMID:8477615no claim extracted — no_outcome_node — measured: subjective clinical improvement in brittle nails (proportion improved), retrospective patient evaluation | brittle nails, subjective clinical improvement proportion (retrospective, no instrument)2026-10-25
- PMID:16773504no claim extracted — no_outcome_node — measured: seizure frequency and urinary organic acid excretion in a single patient with 3-methylcrotonyl-CoA carboxylase deficiency, urine analysis | seizure frequency in a single case report; urinary organic aciduria (3-methylcrotonylglycine, 3-hydroxyisovaleric acid)2026-10-23
- PMID:23269594no claim extracted — no_outcome_node — measured: clinical and neuroradiologic improvement in biotin-responsive basal ganglia disease, descriptive case series, no scale named | clinical and neuroradiologic improvement (unscored, narrative) in biotin-responsive basal ganglia disease2026-10-23
- PMID:9128289no claim extracted — no_outcome_node — measured: lymphocyte mitochondrial carboxylase activity and urinary organic acid excretion in multiple carboxylase deficiency, enzyme assay and organic acid profile | mitochondrial carboxylase activity in lymphocytes and fibroblasts; urinary organic acid excretion; clinical symptom resolution at 10-100 mg biotin/d2026-10-23
- PMID:33928390no claim extracted — no_outcome_node — measured: proportion of inpatient encounters with biotin-susceptible immunoassay testing, retrospective chart review | count of biotin-interference-susceptible immunoassays performed in inpatients receiving high-dose biotin, retrospective chart review2026-10-23
- PMID:40914826no claim extracted — no_outcome_node — measured: incident all-cause dementia and Alzheimer's disease, algorithmically defined outcomes2026-10-23
- PMID:7840079no claim extracted — no_outcome_node — measured: lymphocyte propionyl CoA carboxylase and pyruvate carboxylase activity; plasma biotin concentration | lymphocyte propionyl CoA carboxylase and pyruvate carboxylase activity; plasma biotin concentration (method not stated)2026-10-23
- PMID:10075337no claim extracted — no_outcome_node — measured: 24-hour urinary recovery of biotin and biotin metabolites by HPLC avidin-binding assay (bioavailability) | urinary recovery of biotin and biotin metabolites over 24 h, HPLC avidin-binding assay (bioavailability)2026-10-23
- PMID:22791079no claim extracted — no_outcome_node — measured: muscle cramp onset and severity in hemodialysis patients, no instrument stated | muscle cramp onset and severity in hemodialysis patients, patient-reported2026-10-23
- PMID:31344296no claim extracted — no_outcome_node — measured: Onychodystrophy Global Severity Score (OGSS), nail dystrophy, splitting, dyschromia and pitting composite | Onychodystrophy Global Severity Score (OGSS), clinician-assessed nail dystrophy, splitting, dyschromia and pitting2026-10-23
and 4 more.
Discarded: no comparator4 papers
- PMID:31845825no claim extracted — within_arm_only2026-10-23
- PMID:39913222no claim extracted — comparator_not_absence2026-10-23
- PMID:35791704no claim extracted — comparator_not_absence2026-10-23
- PMID:42693884no claim extracted — comparator_not_absence2026-10-23
Discarded: not retrievable4 papers
- PMID:12203546no PMID parsed, abstract under 200 characters, or no record returned by efetch2026-10-25
- PMID:17506567no PMID parsed, abstract under 200 characters, or no record returned by efetch2026-10-25
- PMID:23089740no PMID parsed, abstract under 200 characters, or no record returned by efetch2026-10-20
- PMID:25200713no PMID parsed, abstract under 200 characters, or no record returned by efetch2026-10-20
Discarded: no extractable result1 paper
- PMID:19491117no claim extracted — no_quantitative_result2026-10-23
Not read yet9 papers
- PMID:107203252026-10-25
- PMID:175459782026-10-25
- PMID:72675422026-10-25
- PMID:248909512026-10-20
- PMID:257871922026-10-20
- PMID:263276792026-10-20
- PMID:205218482026-10-19
- PMID:177075032026-10-13
- PMID:273622882026-10-12
Measured, not recorded
- Compound
- biotin
- Endpoints measured
- 336 endpoints
- Recorded as a finding
- No
Show what was measured
24-h urinary recovery of biotin plus metabolites after oral and intravenous biotin, HPLC avidin-binding assay
approximately 50% recovery after the 2 largest oral doses and the intravenous dose
Not recorded as a finding: this platform holds no node for the endpoint
Urinary recoveries of biotin plus metabolites were similar (approximately 50%) after the 2 largest oral doses and the 1 intravenous dose, suggesting 100% bioavailability of the 2 largest oral doses.
PMID:10075337 · one of two readings recorded this
24-h urinary recovery of biotin plus metabolites
no effect, n = 6
Urinary recoveries of biotin plus metabolites were similar (approximately 50%) after the 2 largest oral doses and the 1 intravenous dose
PMID:10075337 · one of two readings recorded this
urinary biotin as share of biotin plus metabolites
n = 6
For all 4 doses, biotin accounted for >50% of the total of biotin and biotin metabolites in urine
PMID:10075337 · one of two readings recorded this
urinary excretion of biotin as percentage of dose
increases, n = 6
The percentage excretion of biotin was greater when biotin was administered intravenously and for the largest oral dose than for the 2 smallest oral doses
PMID:10075337 · one of two readings recorded this
urinary recovery of biotin plus metabolites over 24 h, HPLC avidin-binding assay, as bioavailability
approximately 50% recovery after the 2 largest oral doses and the intravenous dose
Not recorded as a finding: this platform holds no node for the endpoint
Urinary recoveries of biotin plus metabolites were similar (approximately 50%) after the 2 largest oral doses and the 1 intravenous dose, suggesting 100% bioavailability of the 2 largest oral doses.
PMID:10075337 · one of two readings recorded this
biotin concentration in cerebrospinal fluid and serum by radioligand assay in patients with neurological disorders versus controls
decreases, significantly lower biotin in multiple sclerosis (CSF and serum) than controls
Not recorded as a finding: the compound is what was measured, not what was given
Significantly lower values for biotin were found in patients with multiple sclerosis (both CSF and serum) in comparison to the controls.
PMID:10577274 · one of two readings recorded this
CSF and serum biotin concentration
no effect
No significant differences were observed in other groups of patients
PMID:10577274 · one of two readings recorded this
CSF biotin concentration
decreases
Significantly reduced values for cerebrospinal fluid biotin were found in epileptics compared to controls
PMID:10577274 · one of two readings recorded this
CSF biotin concentration
decreases
Significantly lower values for biotin were found in patients with multiple sclerosis (both CSF and serum) in comparison to the controls
PMID:10577274 · one of two readings recorded this
serum biotin concentration
unclear
whereas, in serum the difference was approaching significance
PMID:10577274 · one of two readings recorded this
serum biotin concentration
decreases
Significantly lower values for biotin were found in patients with multiple sclerosis (both CSF and serum) in comparison to the controls
PMID:10577274 · one of two readings recorded this
Aspergillus antigen positivity in serum
unclear, n = 16
Aspergillus antigens were positive in sera of 9 of 16 (56%) patients who were studied prospectively and in 13 of 73 (19%) patients studied retrospectively
PMID:11503293 · one of two readings recorded this
Aspergillus antigen positivity in serum
unclear, n = 73
Aspergillus antigens were positive in sera of 9 of 16 (56%) patients who were studied prospectively and in 13 of 73 (19%) patients studied retrospectively
PMID:11503293 · one of two readings recorded this
Change in urinary 3-hydroxyisovaleric acid (3-HIA) excretion
decreases, p = 0.006, n = 5
In the early-pregnancy group, 3-HIA excretion decreased (P < 0.006) by 11.7 +/- 3.6 mmol/mol creatinine (mean +/- SEM) in the 5 women who received biotin supplements
PMID:11815321 · one of two readings recorded this
Change in urinary 3-hydroxyisovaleric acid (3-HIA) excretion
decreases, p = 0.002, n = 8
In the late-pregnancy group, 3-HIA excretion decreased (P < 0.002) by 7.1 +/- 1.2 mmol/mol creatinine in the 8 women who received biotin supplements
PMID:11815321 · one of two readings recorded this
Change in urinary 3-hydroxyisovaleric acid (3-HIA) excretion
increases, n = 5
whereas 3-HIA excretion increased by 1.6 +/- 0.6 mmol/mol creatinine in the 5 women who received placebo
PMID:11815321 · one of two readings recorded this
Change in urinary 3-hydroxyisovaleric acid (3-HIA) excretion
increases, n = 8
whereas 3-HIA excretion increased by 0.9 +/- 1.8 mmol/mol creatinine in the 8 women who received placebo
PMID:11815321 · one of two readings recorded this
Median disease-free interval
In the treated glioblastoma patients, median disease-free interval was 28 months (range=9-59); median survival was 33.5 months
PMID:11870507 · one of two readings recorded this
Median disease-free interval
In the treated grade III glioma patients median disease-free interval was 56 months (range=15-60)
PMID:11870507 · one of two readings recorded this
Median overall survival
In the treated glioblastoma patients, median disease-free interval was 28 months (range=9-59); median survival was 33.5 months
PMID:11870507 · one of two readings recorded this
Median survival from diagnosis
n = 12
All 12 control glioblastoma patients died after a median survival from diagnosis of 8 months
PMID:11870507 · one of two readings recorded this
disease progression
unclear
In the group of combined treatment, 9% of patients achieved objective responses, 32% showed stable disease, and 41% had a progression
PMID:15196866 · one of two readings recorded this
disease progression
unclear
in the ip group we observed 6% of objective tumor reduction, stabilization in 31% of pts, and progression in 50%
PMID:15196866 · one of two readings recorded this
objective tumor response
unclear
In the group of combined treatment, 9% of patients achieved objective responses, 32% showed stable disease, and 41% had a progression
PMID:15196866 · one of two readings recorded this
objective tumor response
unclear
in the ip group we observed 6% of objective tumor reduction, stabilization in 31% of pts, and progression in 50%
PMID:15196866 · one of two readings recorded this
stable disease
unclear
In the group of combined treatment, 9% of patients achieved objective responses, 32% showed stable disease, and 41% had a progression
PMID:15196866 · one of two readings recorded this
stable disease
unclear
in the ip group we observed 6% of objective tumor reduction, stabilization in 31% of pts, and progression in 50%
PMID:15196866 · one of two readings recorded this
24-h urinary excretion of biotin, bisnorbiotin, biotin sulfoxide and 3-hydroxyisovaleric acid in smoking women versus nonsmoking controls
decreases, urinary biotin excretion decreased by 30% in smokers, p = 0.04
Not recorded as a finding: the compound is what was measured, not what was given
In the cohort-controlled study, the urinary excretion of biotin decreased by 30% (P = 0.04), and the ratios of urinary bisnorbiotin and biotin sulfoxide to biotin increased significantly, which indicated accelerated catabolism in smokers.
PMID:15447901 · both readings recorded this
ratio of urinary biotin sulfoxide to biotin
increases, p = 0.04
the ratio of urinary biotin sulfoxide to biotin increased (P = 0.04) in these women
PMID:15447901 · one of two readings recorded this
ratios of urinary bisnorbiotin and biotin sulfoxide to biotin
increases
the ratios of urinary bisnorbiotin and biotin sulfoxide to biotin increased significantly, which indicated accelerated catabolism in smokers
PMID:15447901 · one of two readings recorded this
urinary biotin excretion
decreases, p = 0.04
In the cohort-controlled study, the urinary excretion of biotin decreased by 30% (P = 0.04)
PMID:15447901 · one of two readings recorded this
urinary biotin excretion
decreases, p = 0.02
the smoking women in the preliminary study excreted significantly less urinary biotin (P = 0.02)
PMID:15447901 · one of two readings recorded this
urinary excretion of 3-hydroxyisovaleric acid
increases, p = 0.04
the urinary excretion of 3-hydroxyisovaleric acid was greater in the smokers than in the control subjects (P = 0.04)
PMID:15447901 · one of two readings recorded this
plasma cholesterol
no effect
Biotin treatment had no significant effects on cholesterol, glucose and insulin in either the diabetic or nondiabetic subjects
PMID:16677798 · one of two readings recorded this
plasma glucose and insulin, fasting state not stated
no effect, no significant effects
Not recorded as a finding: Fasting not stated for glucose; no insulin node.
Biotin treatment had no significant effects on cholesterol, glucose and insulin in either the diabetic or nondiabetic subjects.
PMID:16677798 · one of two readings recorded this
plasma glucose
no effect
Biotin treatment had no significant effects on cholesterol, glucose and insulin in either the diabetic or nondiabetic subjects
PMID:16677798 · one of two readings recorded this
plasma insulin
no effect
Biotin treatment had no significant effects on cholesterol, glucose and insulin in either the diabetic or nondiabetic subjects
PMID:16677798 · one of two readings recorded this
plasma triacylglycerol
decreases, p = 0.005
We found that the vitamin significantly reduced (P=0.005) plasma triacylglycerol and VLDL concentrations
PMID:16677798 · one of two readings recorded this
plasma triacylglycerol
decreases
Biotin produced the following changes (mean of absolute differences between 0 and 28 day treatment+/-S.E.M.): a) triacylglycerol -0.55+/-0.2 in the diabetic group and -0.92+/-0.36 in the nondiabetic group
PMID:16677798 · one of two readings recorded this
plasma triacylglycerol
decreases
Biotin produced the following changes (mean of absolute differences between 0 and 28 day treatment+/-S.E.M.): a) triacylglycerol -0.55+/-0.2 in the diabetic group and -0.92+/-0.36 in the nondiabetic group
PMID:16677798 · one of two readings recorded this
plasma VLDL concentration, instrument not stated
decreases, p = 0.005
Not recorded as a finding: No outcome node for VLDL.
We found that the vitamin significantly reduced (P=0.005) plasma triacylglycerol and VLDL concentrations.
PMID:16677798 · one of two readings recorded this
plasma VLDL
decreases, p = 0.005
We found that the vitamin significantly reduced (P=0.005) plasma triacylglycerol and VLDL concentrations
PMID:16677798 · one of two readings recorded this
plasma VLDL
decreases
Biotin produced the following changes (mean of absolute differences between 0 and 28 day treatment+/-S.E.M.): a) triacylglycerol -0.55+/-0.2 in the diabetic group and -0.92+/-0.36 in the nondiabetic group; b) VLDL: -0.11+/-0.04 in the diabetic group and -0.18+/-0.07 in the nondiabetic group
PMID:16677798 · one of two readings recorded this
total cholesterol (plasma), glucose and insulin after 28 days of biotin
no effect, no significant effects in either diabetic or nondiabetic subjects
Not recorded as a finding: Total cholesterol is not named as such and glucose is not stated as fasting, so no node requirement is met; one sentence covers three endpoints.
Biotin treatment had no significant effects on cholesterol, glucose and insulin in either the diabetic or nondiabetic subjects.
PMID:16677798 · one of two readings recorded this
hypsarrhythmia
decreases
Biotin therapy led to a dramatic decrease in the frequency of seizures, disappearance of hypsarrhythmia, and near normalisation of organic aciduria
PMID:16773504 · one of two readings recorded this
MCC enzyme activity
decreases
Biochemical findings showed partial MCC deficiency in cultured fibroblasts
PMID:16773504 · one of two readings recorded this
organic aciduria (3-methylcrotonylglycine, 3-hydroxyisovaleric acid)
decreases
Biotin therapy led to a dramatic decrease in the frequency of seizures, disappearance of hypsarrhythmia, and near normalisation of organic aciduria
PMID:16773504 · one of two readings recorded this
seizure frequency, hypsarrhythmia and urinary organic aciduria after biotin therapy in one boy with MCC deficiency
decreases, dramatic decrease in the frequency of seizures, near normalisation of organic aciduria, n = 1
Not recorded as a finding: this platform holds no node for the endpoint
Biotin therapy led to a dramatic decrease in the frequency of seizures, disappearance of hypsarrhythmia, and near normalisation of organic aciduria.
PMID:16773504 · one of two readings recorded this
seizure frequency
decreases
Biotin therapy led to a dramatic decrease in the frequency of seizures, disappearance of hypsarrhythmia, and near normalisation of organic aciduria
PMID:16773504 · one of two readings recorded this
seizures after biotin plus protein-restricted diet
unclear
However, severe psychomotor delay persisted, and the seizures partially reoccurred
PMID:16773504 · one of two readings recorded this
serum carnitine level
decreases
Carnitine serum levels were decreased
PMID:16773504 · one of two readings recorded this
Activation coefficient of PCC (activated/control PBL PCC activity)
increases, p = 0.003, n = 7
By day 28, the activation coefficient of PCC had increased significantly (P = 0.003) and was above the upper limit of normal in 6 of 7 subjects
PMID:16895887 · one of two readings recorded this
Peripheral blood lymphocyte propionyl-CoA carboxylase (PCC) activity
decreases, p = 0.0001, n = 7
By day 14, PCC activity had decreased (P < 0.0001) to below the lower limit of normal in all subjects
PMID:16895887 · one of two readings recorded this
decaprenyl diphosphate synthase activity in patient fibroblasts
decreases
Biochemical assays with radiolabeled substrates indicated a severe defect in decaprenyl diphosphate synthase in the patient's fibroblasts
PMID:17186472 · one of two readings recorded this
clinical response to biotin therapy
increases
We report a case of biotin-responsive basal ganglia disease suspected clinically, corroborated by neuroimaging and a dramatic response to biotin therapy
PMID:19491117 · one of two readings recorded this
share of trimethoprim R plasmids encoding type IIIa and type VII DHFR
increases
This was particularly true of the type IIIa and type VII enzymes which together accounted for 27% of the trimethoprim R plasmids examined in 1987-8
PMID:1993453 · one of two readings recorded this
onset and severity of muscle cramps during and after HD
decreases, n = 12
Oral administration of 1 mg/day biotin promptly reduced the onset and the severity of cramps in 12 patients both during and after HD
PMID:22791079 · one of two readings recorded this
onset and severity of muscle cramps during and after hemodialysis; plasma biotin by ELISA
decreases
Not recorded as a finding: this platform holds no node for the endpoint
Oral administration of 1 mg/day biotin promptly reduced the onset and the severity of cramps in 12 patients both during and after HD.
PMID:22791079 · both readings recorded this
plasma biotin (ELISA)
increases, p = 0.0001
Plasma biotin levels were elevated in 27 HD patients at baseline compared with healthy volunteers [451 (377 - 649) vs. 224 (148 - 308) ng/l, median (lower-upper quartiles); p < 0.0001]
PMID:22791079 · one of two readings recorded this
plasma biotin (ELISA)
increases, p = 0.001
the biotin levels were significantly higher in biotin-ineffective 7 patients than biotin-effective 7 patients [1,064 (710 - 1,187) vs. 445 (359 - 476) ng/l; p < 0.001]
PMID:22791079 · one of two readings recorded this
atrophy and gliosis in affected regions
unclear
Atrophy and gliosis in the affected regions were observed in patients with chronic disease
PMID:23269594 · one of two readings recorded this
brain MRI lesions in caudate nucleus, putamen, cortex and brainstem
unclear
Vasogenic edema characterized the acute crises as demonstrated by diffusion-weighted imaging/apparent diffusion coefficient MRI
PMID:23269594 · one of two readings recorded this
clinical and neuroradiologic improvement
increases
Early treatment with a combination of biotin and thiamine resulted in clinical and neuroradiologic improvement
PMID:23269594 · one of two readings recorded this
death and neurologic sequelae (dystonia, mental retardation, epilepsy)
unclear
Death and neurologic sequelae including dystonia, mental retardation, and epilepsy were observed in those who were not treated or were treated late
PMID:23269594 · one of two readings recorded this
abnormal signals in mesencephalon, cerebral cortical-subcortical regions and thalami
In 80%, discrete abnormal signals were observed in the mesencephalon, cerebral cortical-subcortical regions, and thalami
PMID:24812013 · one of two readings recorded this
bilateral caudate nuclei lesions with putamen involvement, globus pallidus spared (MR imaging)
Brain MR imaging showed bilateral lesions in the caudate nuclei with complete or partial involvement of the putamen and sparing of the globus pallidus in all cases
PMID:24812013 · one of two readings recorded this
brain MR imaging signal abnormality of mesencephalon, cortex, white matter and caudate/putamen necrosis before and 2-8 weeks after treatment in biotin-responsive basal ganglia disease
decreases, signal abnormality resolved; caudate and putamen necrosis persisted in all patients
Not recorded as a finding: the intervention held more than the compound
The signal abnormality of the mesencephalon, cortex, and white matter disappeared after treatment whereas the caudate and putamen necrosis persisted in all patients, including those who became asymptomatic.
PMID:24812013 · one of two readings recorded this
caudate and putamen necrosis after treatment
no effect
The signal abnormality of the mesencephalon, cortex, and white matter disappeared after treatment whereas the caudate and putamen necrosis persisted in all patients
PMID:24812013 · one of two readings recorded this
cerebellar involvement
The cerebellum was involved in 13.3%
PMID:24812013 · one of two readings recorded this
mesencephalon, cortex and white matter signal abnormality after treatment
decreases
The signal abnormality of the mesencephalon, cortex, and white matter disappeared after treatment whereas the caudate and putamen necrosis persisted in all patients
PMID:24812013 · one of two readings recorded this
patchy deep white matter affection in advanced disease
In 53%, when the disease was advanced, patchy deep white matter affection was found
PMID:24812013 · one of two readings recorded this
biotin status biomarkers (plasma biotin, urinary biotin, urinary bisnorbiotin, urinary 3-hydroxyisovaleric acid) in pregnant, lactating and control women fed 57 ug biotin/d
no effect, no differences in plasma biotin, urinary biotin or urinary bisnorbiotin between pregnant and control women
Not recorded as a finding: the compound is what was measured, not what was given
No differences (P > 0.05) were detected in plasma biotin, urinary biotin, or urinary bisnorbiotin between pregnant and control women.
PMID:25122647 · one of two readings recorded this
Plasma biotin
no effect, p = 0.05
No differences (P > 0.05) were detected in plasma biotin, urinary biotin, or urinary bisnorbiotin between pregnant and control women
PMID:25122647 · one of two readings recorded this
Urinary 3-hydroxyisovaleric acid (3-HIA) excretion
decreases, p = 0.04
lactating women excreted 23% less (P = 0.04) urinary 3-HIA and 26% less (P = 0.05) urinary 3-HIA-carnitine
PMID:25122647 · one of two readings recorded this
Urinary 3-hydroxyisovaleric acid (3-HIA) excretion
increases, p = 0.001
pregnant women excreted 69% more (vs. control; P < 0.001) 3-hydroxyisovaleric acid (3-HIA)
PMID:25122647 · one of two readings recorded this
Urinary 3-hydroxyisovaleryl-carnitine (3-HIA-carnitine) excretion
decreases, p = 0.05
lactating women excreted 23% less (P = 0.04) urinary 3-HIA and 26% less (P = 0.05) urinary 3-HIA-carnitine
PMID:25122647 · one of two readings recorded this
Urinary 3-hydroxyisovaleryl-carnitine (3-HIA-carnitine) excretion
decreases, p = 0.05
urinary excretion of 3-hydroxyisovaleryl-carnitine (3-HIA-carnitine), a downstream metabolite of 3-HIA, was 27% lower (P = 0.05) among pregnant (vs. control) women
PMID:25122647 · one of two readings recorded this
urinary and plasma biotin biomarkers (3-hydroxyisovaleric acid, 3-HIA-carnitine, biotin, bisnorbiotin) in pregnant, lactating and control women on a fixed 57 ug/d dietary biotin intake
increases, 76% more urinary bisnorbiotin in lactating vs control women, p = 0.001
Not recorded as a finding: the compound is what was measured, not what was given
Lactating women excreted 76% more (vs. control; P = 0.001) of the biotin catabolite bisnorbiotin, indicating that lactation accelerates biotin turnover and loss.
PMID:25122647 · one of two readings recorded this
Urinary biotin
no effect, p = 0.05
No differences (P > 0.05) were detected in plasma biotin, urinary biotin, or urinary bisnorbiotin between pregnant and control women
PMID:25122647 · one of two readings recorded this
Urinary bisnorbiotin excretion
increases, p = 0.001
Lactating women excreted 76% more (vs. control; P = 0.001) of the biotin catabolite bisnorbiotin
PMID:25122647 · one of two readings recorded this
Urinary bisnorbiotin
no effect, p = 0.05
No differences (P > 0.05) were detected in plasma biotin, urinary biotin, or urinary bisnorbiotin between pregnant and control women
PMID:25122647 · one of two readings recorded this
agreement between TRFIA and ELISA values
The values determined by the biotin-streptavidin-TRFIA and ELISA correlated well (R(2) = 0.8927)
PMID:25269884 · one of two readings recorded this
anti-CCP detection limit
featured a detection limit up to 0.5 U/ml for anti-CCP
PMID:25269884 · one of two readings recorded this
assay linear range, lower limit
The presented method produced a wide linear range from 0.58 to 9,463 U/ml
PMID:25269884 · one of two readings recorded this
assay linear range, upper limit
The presented method produced a wide linear range from 0.58 to 9,463 U/ml
PMID:25269884 · one of two readings recorded this
spiked recovery, highest
The method was applied to determine anti-CCP in serum samples with satisfied recoveries of 96.45-104.63%
PMID:25269884 · one of two readings recorded this
spiked recovery, lowest
The method was applied to determine anti-CCP in serum samples with satisfied recoveries of 96.45-104.63%
PMID:25269884 · one of two readings recorded this
accuracy of UHPLC-MS/MS biotin assay
The accuracy varied from -0.7 to 8.2%
PMID:26715368 · one of two readings recorded this
intra- and inter-day precision of UHPLC-MS/MS biotin assay
The intra- and inter-day precisions were all <7.1%
PMID:26715368 · one of two readings recorded this
RSV culture positivity
n = 156
Of 156 nasopharyngeal swab specimens from infants with respiratory symptoms, 81 (52%) yielded RSV in culture
PMID:2696927 · one of two readings recorded this
sensitivity and specificity of a biotin-enhanced RSV antigen enzyme immunoassay against culture and immunofluorescence
sensitivity 95%, specificity 92% versus culture, n = 156
Not recorded as a finding: the compound was a reagent, not an exposure
Compared with culture the sensitivity of the EIA was 95% and specificity was 92%; the specificity increased to 97% with a blocking assay.
PMID:2696927 · one of two readings recorded this
Sensitivity of bedside EIA by housestaff versus laboratory immunofluorescence
decreases, n = 49
the sensitivity of the EIA was lower (78%) while specificity remained high (95%)
PMID:2696927 · one of two readings recorded this
Sensitivity of biotin-enhanced EIA versus culture
n = 156
Compared with culture the sensitivity of the EIA was 95% and specificity was 92%
PMID:2696927 · one of two readings recorded this
Sensitivity of biotin-enhanced EIA versus immunofluorescence
Compared with immunofluorescence the sensitivity of EIA was 92% and specificity was 93%
PMID:2696927 · one of two readings recorded this
Specificity of bedside EIA by housestaff versus laboratory immunofluorescence
n = 49
the sensitivity of the EIA was lower (78%) while specificity remained high (95%)
PMID:2696927 · one of two readings recorded this
Specificity of biotin-enhanced EIA versus culture with blocking assay
increases, n = 156
the specificity increased to 97% with a blocking assay
PMID:2696927 · one of two readings recorded this
Specificity of biotin-enhanced EIA versus culture
n = 156
Compared with culture the sensitivity of the EIA was 95% and specificity was 92%
PMID:2696927 · one of two readings recorded this
Specificity of biotin-enhanced EIA versus immunofluorescence
Compared with immunofluorescence the sensitivity of EIA was 92% and specificity was 93%
PMID:2696927 · one of two readings recorded this
Change in 9-HPT best hand
no effect, p = 0.98, n = 154
Best hand | 2.06 (5.21) | 1.40 (7.06) | 0.98 | 3.43 (8.44) | 2.76 (9.20) | 0.77
PMID:27589059 · one of two readings recorded this
Change in 9-HPT best hand
no effect, p = 0.77, n = 133
Best hand | 2.06 (5.21) | 1.40 (7.06) | 0.98 | 3.43 (8.44) | 2.76 (9.20) | 0.77
PMID:27589059 · one of two readings recorded this
Change in 9-HPT worst hand
no effect, p = 0.67, n = 154
Worst hand | 3.14 (25.03) | 1.49 (14.98) | 0.67 | 8.87 (33.86) | 7.70 (32.17) | 0.77
PMID:27589059 · one of two readings recorded this
Change in 9-HPT worst hand
no effect, p = 0.77, n = 133
Worst hand | 3.14 (25.03) | 1.49 (14.98) | 0.67 | 8.87 (33.86) | 7.70 (32.17) | 0.77
PMID:27589059 · one of two readings recorded this
Change in EDSS bowel and bladder subscore
no effect, p = 0.68, n = 154
Bowel and bladder | 0.14 (0.83) | 0.20 (0.98) | 0.68 | 0.12 (0.89) | 0.02 (0.92) | 0.81
PMID:27589059 · one of two readings recorded this
Change in EDSS bowel and bladder subscore
no effect, p = 0.81, n = 133
Bowel and bladder | 0.14 (0.83) | 0.20 (0.98) | 0.68 | 0.12 (0.89) | 0.02 (0.92) | 0.81
PMID:27589059 · one of two readings recorded this
Change in EDSS brain stem subscore
no effect, p = 0.19, n = 154
Brain stem | 0.10 (0.69) | −0.08 (0.82) | 0.19 | 0.09 (0.89) | 0.14 (0.84) | 0.58
PMID:27589059 · one of two readings recorded this
Change in EDSS brain stem subscore
no effect, p = 0.58, n = 133
Brain stem | 0.10 (0.69) | −0.08 (0.82) | 0.19 | 0.09 (0.89) | 0.14 (0.84) | 0.58
PMID:27589059 · one of two readings recorded this
Change in EDSS cerebellar subscore
no effect, p = 0.54, n = 154
Cerebellar | 0.19 (0.86) | 0.14 (1.12) | 0.54 | 0.09 (0.91) | 0.05 (1.53) | 0.82
PMID:27589059 · one of two readings recorded this
Change in EDSS cerebellar subscore
no effect, p = 0.82, n = 133
Cerebellar | 0.19 (0.86) | 0.14 (1.12) | 0.54 | 0.09 (0.91) | 0.05 (1.53) | 0.82
PMID:27589059 · one of two readings recorded this
Change in EDSS cerebral subscore
no effect, p = 0.26, n = 154
Cerebral | −0.08 (0.76) | 0.08 (0.91) | 0.26 | −0.01 (0.89) | 0.00 (0.96) | 0.75
PMID:27589059 · one of two readings recorded this
Change in EDSS cerebral subscore
no effect, p = 0.75, n = 133
Cerebral | −0.08 (0.76) | 0.08 (0.91) | 0.26 | −0.01 (0.89) | 0.00 (0.96) | 0.75
PMID:27589059 · one of two readings recorded this
Change in EDSS pyramidal subscore
no effect, p = 0.54, n = 154
Pyramidal | −0.03 (0.55) | 0.04 (0.53) | 0.54 | 0.12 (0.61) | 0.12 (0.59) | 0.88
PMID:27589059 · one of two readings recorded this
Change in EDSS pyramidal subscore
no effect, p = 0.88, n = 133
Pyramidal | −0.03 (0.55) | 0.04 (0.53) | 0.54 | 0.12 (0.61) | 0.12 (0.59) | 0.88
PMID:27589059 · one of two readings recorded this
Change in EDSS sensory subscore
no effect, p = 0.09, n = 154
Sensory | −0.25 (0.93) | 0.06 (0.88) | 0.09 | −0.08 (0.96) | −0.17 (0.99) | 0.64
PMID:27589059 · one of two readings recorded this
Change in EDSS sensory subscore
no effect, p = 0.64, n = 133
Sensory | −0.25 (0.93) | 0.06 (0.88) | 0.09 | −0.08 (0.96) | −0.17 (0.99) | 0.64
PMID:27589059 · one of two readings recorded this
Change in EDSS visual subscore
no effect, p = 0.18, n = 154
Visual | 0.05 (0.81) | −0.10 (0.50) | 0.18 | 0.04 (1.00) | 0.17 (1.19) | 0.73
PMID:27589059 · one of two readings recorded this
Change in EDSS visual subscore
no effect, p = 0.73, n = 133
Visual | 0.05 (0.81) | −0.10 (0.50) | 0.18 | 0.04 (1.00) | 0.17 (1.19) | 0.73
PMID:27589059 · one of two readings recorded this
Change in EDSS
decreases, p = 0.01, n = 154
Change in EDSS, a mean (SD) | −0.03 (0.50) | 0.13 (0.33) | 0.01 | 0.04 (0.62) | 0.15 (0.37) | 0.13
PMID:27589059 · one of two readings recorded this
Change in EDSS
no effect, p = 0.13, n = 133
Change in EDSS, a mean (SD) | −0.03 (0.50) | 0.13 (0.33) | 0.01 | 0.04 (0.62) | 0.15 (0.37) | 0.13
PMID:27589059 · one of two readings recorded this
Change in MFIS
no effect, p = 0.85, n = 154
Change in MFIS, a mean (SD) | 1.38 (16.04) | 1.30 (15.69) | 0.85 | −0.40 (13.49) | 0.79 (13.88) | 0.97
PMID:27589059 · one of two readings recorded this
Change in MFIS
no effect, p = 0.97, n = 133
Change in MFIS, a mean (SD) | 1.38 (16.04) | 1.30 (15.69) | 0.85 | −0.40 (13.49) | 0.79 (13.88) | 0.97
PMID:27589059 · one of two readings recorded this
Change in MSWS
no effect, p = 0.81, n = 154
Change in MSWS, a mean (SD) (seconds) | 0.79 (17.12) | 5.26 (22.51) | 0.81 | 2.06 (17.22) | 5.05 (27.07) | 0.64
PMID:27589059 · one of two readings recorded this
Change in MSWS
no effect, p = 0.64, n = 133
Change in MSWS, a mean (SD) (seconds) | 0.79 (17.12) | 5.26 (22.51) | 0.81 | 2.06 (17.22) | 5.05 (27.07) | 0.64
PMID:27589059 · one of two readings recorded this
Change in SF-36 Emotional well-being
unclear, p = 0.05, n = 154
Emotional well-being | −4.41 (17.15) | 1.33 (13.78) | 0.05 | −1.31 (17.70) | −0.38 (13.88) | 0.83
PMID:27589059 · one of two readings recorded this
Change in SF-36 Emotional well-being
no effect, p = 0.83, n = 133
Emotional well-being | −4.41 (17.15) | 1.33 (13.78) | 0.05 | −1.31 (17.70) | −0.38 (13.88) | 0.83
PMID:27589059 · one of two readings recorded this
Change in SF-36 Energy or fatigue
no effect, p = 0.25, n = 154
Energy or fatigue | −2.85 (19.01) | 0.82 (14.87) | 0.25 | 1.35 (16.91) | 6.71 (17.21) | 0.07
PMID:27589059 · one of two readings recorded this
Change in SF-36 Energy or fatigue
no effect, p = 0.07, n = 133
Energy or fatigue | −2.85 (19.01) | 0.82 (14.87) | 0.25 | 1.35 (16.91) | 6.71 (17.21) | 0.07
PMID:27589059 · one of two readings recorded this
Change in SF-36 General health
decreases, p = 0.03, n = 154
General health | −4.43 (16.75) | 2.25 (16.23) | 0.03 | −3.95 (15.68) | 1.37 (19.26) | 0.17
PMID:27589059 · one of two readings recorded this
Change in SF-36 General health
no effect, p = 0.17, n = 133
General health | −4.43 (16.75) | 2.25 (16.23) | 0.03 | −3.95 (15.68) | 1.37 (19.26) | 0.17
PMID:27589059 · one of two readings recorded this
Change in SF-36 Health change
no effect, p = 0.9, n = 154
Health change | 3.54 (24.49) | 3.65 (29.17) | 0.90 | 1.44 (24.81) | 14.10 (24.19) | 0.01
PMID:27589059 · one of two readings recorded this
Change in SF-36 Health change
decreases, p = 0.01, n = 133
Health change | 3.54 (24.49) | 3.65 (29.17) | 0.90 | 1.44 (24.81) | 14.10 (24.19) | 0.01
PMID:27589059 · one of two readings recorded this
Change in SF-36 Pain
no effect, p = 0.46, n = 154
Pain | 0.12 (18.93) | −2.55 (19.79) | 0.46 | −1.89 (20.73) | −1.61 (16.81) | 0.86
PMID:27589059 · one of two readings recorded this
Change in SF-36 Pain
no effect, p = 0.86, n = 133
Pain | 0.12 (18.93) | −2.55 (19.79) | 0.46 | −1.89 (20.73) | −1.61 (16.81) | 0.86
PMID:27589059 · one of two readings recorded this
Change in SF-36 Physical functioning
no effect, p = 0.73, n = 154
Physical functioning | −1.72 (26.70) | 0.50 (22.14) | 0.73 | −3.53 (26.45) | −1.36 (23.58) | 0.92
PMID:27589059 · one of two readings recorded this
Change in SF-36 Physical functioning
no effect, p = 0.92, n = 133
Physical functioning | −1.72 (26.70) | 0.50 (22.14) | 0.73 | −3.53 (26.45) | −1.36 (23.58) | 0.92
PMID:27589059 · one of two readings recorded this
Change in SF-36 Role limitations due to emotional problems
no effect, p = 0.88, n = 154
Role limitations due to emotional problems | 2.43 (43.00) | −0.67 (45.42) | 0.88 | 0.18 (46.11) | 7.14 (45.70) | 0.48
PMID:27589059 · one of two readings recorded this
Change in SF-36 Role limitations due to emotional problems
no effect, p = 0.48, n = 133
Role limitations due to emotional problems | 2.43 (43.00) | −0.67 (45.42) | 0.88 | 0.18 (46.11) | 7.14 (45.70) | 0.48
PMID:27589059 · one of two readings recorded this
Change in SF-36 Role limitations due to physical health
no effect, p = 0.26, n = 154
Role limitations due to physical health | 8.58 (46.29) | 1.17 (33.71) | 0.26 | 2.01 (44.35) | 6.35 (33.43) | 0.36
PMID:27589059 · one of two readings recorded this
Change in SF-36 Role limitations due to physical health
no effect, p = 0.36, n = 133
Role limitations due to physical health | 8.58 (46.29) | 1.17 (33.71) | 0.26 | 2.01 (44.35) | 6.35 (33.43) | 0.36
PMID:27589059 · one of two readings recorded this
Change in SF-36 Social functioning
no effect, p = 0.97, n = 154
Social functioning | −0.24 (28.38) | −0.25 (26.52) | 0.97 | 0.82 (25.60) | 2.08 (28.55) | 0.99
PMID:27589059 · one of two readings recorded this
Change in SF-36 Social functioning
no effect, p = 0.99, n = 133
Social functioning | −0.24 (28.38) | −0.25 (26.52) | 0.97 | 0.82 (25.60) | 2.08 (28.55) | 0.99
PMID:27589059 · one of two readings recorded this
Change in timed 25-foot walk (TW25)
no effect, p = 0.64, n = 154
Change in TW25, a mean (SD) (%) | 67.71 (203.27) | 98.18 (253.73) | 0.64 | 95.77 (221.66) | 121.51 (256.29) | 0.82
PMID:27589059 · one of two readings recorded this
Change in timed 25-foot walk (TW25)
no effect, p = 0.82, n = 133
Change in TW25, a mean (SD) (%) | 67.71 (203.27) | 98.18 (253.73) | 0.64 | 95.77 (221.66) | 121.51 (256.29) | 0.82
PMID:27589059 · one of two readings recorded this
Clinician-assessed Clinical Global Impression (CGI)
decreases, p = 0.001, n = 154
CGI, b mean (SD) | 4.05 (0.81) | 4.62 (0.75) | <0.001 | 4.17 (0.97) | 4.21 (0.75) | 0.93
PMID:27589059 · one of two readings recorded this
Clinician-assessed Clinical Global Impression (CGI)
no effect, p = 0.93, n = 133
CGI, b mean (SD) | 4.05 (0.81) | 4.62 (0.75) | <0.001 | 4.17 (0.97) | 4.21 (0.75) | 0.93
PMID:27589059 · one of two readings recorded this
Enlarging MRI lesions at month 12
no effect, p = 0.3, n = 70
Four (8.5%) MD1003-treated patients had enlarging lesions (vs none in the placebo arm; p = 0.30)
PMID:27589059 · one of two readings recorded this
New MS-specific lesions on MRI at month 12
no effect, p = 0.36, n = 70
new MS-specific lesions in 11 of the 47 (23.4%) MD1003-treated patients and 3 of the 23 (13.0%) placebo-treated patients (p = 0.36)
PMID:27589059 · one of two readings recorded this
Patients with >20% improvement in TW25 times at month 9, confirmed at month 12 (post hoc)
increases, p = 0.03, n = 154
nine (8.7%) patients had >20% improvement in TW25 times at month 9, confirmed at month 12, compared with the last pre-treatment visit versus none in the placebo group (p = 0.03)
PMID:27589059 · one of two readings recorded this
Patients with EDSS progression
no effect, p = 0.07, n = 154
Patients with EDSS progression, c, f n (%) | 4 (4.2) | 6 (13.6) | 0.07 | 8 (9.9) | 13 (31.7) | 0.005
PMID:27589059 · one of two readings recorded this
Patients with EDSS progression
decreases, p = 0.005, n = 133
Patients with EDSS progression, c, f n (%) | 4 (4.2) | 6 (13.6) | 0.07 | 8 (9.9) | 13 (31.7) | 0.005
PMID:27589059 · one of two readings recorded this
Patients with improvement of EDSS and TW25
no effect, p = 0.99, n = 154
Patients with improvement of EDSS and TW25, c, d n (%) | 2 (1.9) | 0 (0.0) | 0.99 | 2 (2.2) | 0 (0.0) | 0.99
PMID:27589059 · one of two readings recorded this
Patients with improvement of EDSS and TW25
no effect, p = 0.99, n = 133
Patients with improvement of EDSS and TW25, c, d n (%) | 2 (1.9) | 0 (0.0) | 0.99 | 2 (2.2) | 0 (0.0) | 0.99
PMID:27589059 · one of two readings recorded this
Patients with improvement of EDSS
increases, p = 0.03, n = 154
Patients with improvement of EDSS, c, e n (%) | 10 (9.7) | 0 (0.0) | 0.03 | 10 (11.0) | 2 (4.8) | 0.34
PMID:27589059 · one of two readings recorded this
Patients with improvement of EDSS
no effect, p = 0.34, n = 133
Patients with improvement of EDSS, c, e n (%) | 10 (9.7) | 0 (0.0) | 0.03 | 10 (11.0) | 2 (4.8) | 0.34
PMID:27589059 · one of two readings recorded this
Patients with stable EDSS score
no effect, p = 0.68, n = 154
Patients with stable EDSS score, c n (%) | 81 (78.6) | 38 (74.5) | 0.68 | 63 (69.2) | 26 (61.9) | 0.43
PMID:27589059 · one of two readings recorded this
Patients with stable EDSS score
no effect, p = 0.43, n = 133
Patients with stable EDSS score, c n (%) | 81 (78.6) | 38 (74.5) | 0.68 | 63 (69.2) | 26 (61.9) | 0.43
PMID:27589059 · one of two readings recorded this
Post-gadolinium enhancing T1 lesion at month 12
no effect, p = 0.99, n = 70
two (4.3%) had at least one post-gadolinium enhancing lesion on T1 sequence (vs none in the placebo arm; p = 0.99)
PMID:27589059 · one of two readings recorded this
Proportion of patients unable to perform TW25 (truncated at 180 seconds)
no effect, p = 0.07, n = 154
the proportion of patients unable to successfully perform the TW25 (values truncated at 180 seconds) progressed at a lower rate in the MD1003 group (from 1.0% at month 0 to 6.4% at month 12), than in the placebo group (from 2.0% at month 0 to 19.0% at month 12; p = 0.07)
PMID:27589059 · one of two readings recorded this
proportion of patients with disability reversal (EDSS decrease or 20% decrease in timed 25-foot walk) at month 9 confirmed at month 12, composite responder proportion
increases, 13 (12.6%) MD1003 vs none on placebo; difference in proportions 0.13, p = 0.005
Not recorded as a finding: primary composite responder endpoint; no outcome node for MS disability-reversal composite
A total of 13 (12.6%; 95% confidence interval (CI): 6.9%–20.6%) patients treated with MD1003 had a reduction in MS-related disability at month 9, confirmed at month 12, compared with none in the placebo arm (; p = 0.005; effect estimate for difference in proportions: 0.13; asymptotic 95% CI: 0.06–0.19).
PMID:27589059 · one of two readings recorded this
Proportion with reduced MS-related disability at 18 months (confirmed at 24 months)
n = 91
A total of 12 of the 91 (13.2%; 95% CI: 7.0%–21.9%) patients initially treated with MD1003 had reduced MS-related disability at 18 months (confirmed at 24 months; Figure 2)
PMID:27589059 · one of two readings recorded this
Proportion with reduced MS-related disability at 18 months (confirmed at 24 months)
n = 42
After switching to MD1003, 3 of the 42 (7.1%; 95% CI: 1.5%–19.5%) patients in the placebo > MD1003 arm had reduced disability at 18 months (confirmed at 24 months)
PMID:27589059 · one of two readings recorded this
Proportion with reduced MS-related disability at month 24
n = 133
At month 24, 14 of the 91 (15.4%) patients in the MD1003 > MD1003 arm and 5 of the 42 (11.9%) patients in the placebo > MD1003 arm had reduced MS-related disability
PMID:27589059 · one of two readings recorded this
Proportion with reversal of MS-related disability at month 9, confirmed at month 12
n = 58
the primary endpoint was reached more frequently in MD1003-treated patients not taking fampridine (12 of 58; 20.3%) than those taking fampridine (1 of 45; 2.3%)
PMID:27589059 · one of two readings recorded this
Proportion with reversal of MS-related disability at month 9, confirmed at month 12
n = 45
the primary endpoint was reached more frequently in MD1003-treated patients not taking fampridine (12 of 58; 20.3%) than those taking fampridine (1 of 45; 2.3%)
PMID:27589059 · one of two readings recorded this
Proportion with reversal of MS-related disability at month 9, confirmed at month 12
increases, p = 0.009, n = 129
Results were similar in the per-protocol population (n = 129): 13 of the 87 (14.9%) MD1003-treated patients achieved the primary endpoint compared with none in the placebo arm (n = 42; p = 0.009)
PMID:27589059 · one of two readings recorded this
Proportion with reversal of MS-related disability at month 9, confirmed at month 12
n = 28
baseline EDSS 4.5–5.5 (6 of 28; 21.4%) versus EDSS 6–7 (7 of 75; 9.3%; Table S1)
PMID:27589059 · one of two readings recorded this
Proportion with reversal of MS-related disability at month 9, confirmed at month 12
n = 75
baseline EDSS 4.5–5.5 (6 of 28; 21.4%) versus EDSS 6–7 (7 of 75; 9.3%; Table S1)
PMID:27589059 · one of two readings recorded this
Proportion with reversal of MS-related disability (EDSS or TW25 improvement) at month 9, confirmed at month 12
increases, p = 0.005, n = 154
A total of 13 (12.6%; 95% confidence interval (CI): 6.9%–20.6%) patients treated with MD1003 had a reduction in MS-related disability at month 9, confirmed at month 12, compared with none in the placebo arm (; p = 0.005; effect estimate for difference in proportions: 0.13; asymptotic 95% CI: 0.06–0.19)
PMID:27589059 · one of two readings recorded this
Subject-assessed Clinical Global Impression (SGI)
decreases, p = 0.009, n = 154
SGI, b mean (SD) | 4.27 (1.05) | 4.76 (0.89) | 0.009 | 4.47 (1.07) | 4.41 (0.87) | 0.72
PMID:27589059 · one of two readings recorded this
Subject-assessed Clinical Global Impression (SGI)
no effect, p = 0.72, n = 133
SGI, b mean (SD) | 4.27 (1.05) | 4.76 (0.89) | 0.009 | 4.47 (1.07) | 4.41 (0.87) | 0.72
PMID:27589059 · one of two readings recorded this
timed 25-foot walk time, mean change
no effect, mean TW25 times increased more in placebo than MD1003, not significant
Not recorded as a finding: no outcome node for timed 25-foot walk
Mean TW25 times increased more in the placebo arm than in the MD1003 arm, but this difference was not significant (Table 3).
PMID:27589059 · one of two readings recorded this
fT4, TSH and PTH with non-streptavidin assays in high-biotin plasmas
no effect
All results with the alternative methods were normal except two slight PTH elevations
PMID:28222020 · one of two readings recorded this
hormone results in high-biotin plasmas before and after N5
increases
Most hormones results were abnormal, but normalized after N5
PMID:28222020 · one of two readings recorded this
hormone results other than PTH after N5 in biotin-unsupplemented patients
no effect
In the 39 biotin-unsupplemented patients, the N5 protocol did not affect the results for any of the hormones, apart from an 8.4% decrease in PTH
PMID:28222020 · one of two readings recorded this
PTH change after N5 in biotin-unsupplemented patients
decreases
In the 39 biotin-unsupplemented patients, the N5 protocol did not affect the results for any of the hormones, apart from an 8.4% decrease in PTH
PMID:28222020 · one of two readings recorded this
residual biotin after N5 procedure
decreases
After the N5 protocol, the biotin concentration was below the detection limit in all but two samples (8.3 and 27.6 μg/L)
PMID:28222020 · one of two readings recorded this
Mean change from baseline in visual acuity (logMAR, 100% contrast, selected eye)
no effect, p = 0.66, n = 93
the mean change in the primary endpoint was nonsignificantly larger (p = 0.66) with MD1003 (- 0.061 logMAR, + 3.1 letters) than with placebo (- 0.036 logMAR, + 1.8 letters)
PMID:29808469 · one of two readings recorded this
mean change from baseline to month 6 in visual acuity, logMAR at 100% contrast of the selected eye
- 0.061 logMAR with MD1003 versus - 0.036 logMAR with placebo, p = 0.66
Not recorded as a finding: this platform holds no node for the endpoint
The study did not meet its primary endpoint, as the mean change in the primary endpoint was nonsignificantly larger (p = 0.66) with MD1003 (- 0.061 logMAR, + 3.1 letters) than with placebo (- 0.036 logMAR, + 1.8 letters).
PMID:29808469 · one of two readings recorded this
Mean change in 100% contrast visual acuity, letters
no effect, p = 0.66, n = 93
the mean change in the primary endpoint was nonsignificantly larger (p = 0.66) with MD1003 (- 0.061 logMAR, + 3.1 letters) than with placebo (- 0.036 logMAR, + 1.8 letters)
PMID:29808469 · one of two readings recorded this
Mean change in 100% contrast visual acuity (letters)
no effect, p = 0.45
Pre-planned subgroup analyses showed that 100% contrast VA improved by a mean of + 2.8 letters (- 0.058 logMAR) with MD1003 and worsened by - 1.5 letters (+ 0.029 logMAR) with placebo (p = 0.45) in the subgroup of patients with PON
PMID:29808469 · one of two readings recorded this
visual acuity, mean change from baseline to month 6 in logMAR at 100% contrast of the selected eye
- 0.061 logMAR with MD1003 versus - 0.036 logMAR with placebo, p = 0.66
Not recorded as a finding: the paper never states the instrument the node requires
The study did not meet its primary endpoint, as the mean change in the primary endpoint was nonsignificantly larger (p = 0.66) with MD1003 (- 0.061 logMAR, + 3.1 letters) than with placebo (- 0.036 logMAR, + 1.8 letters).
PMID:29808469 · one of two readings recorded this
OGSS reduction from baseline
decreases
At Month 4, OGSS was reduced by 57% (HPC-NL) and 62% (HPC-NL + B)
PMID:31344296 · one of two readings recorded this
Onychodystrophy Global Severity Score (OGSS) at baseline
At baseline, the OGSS, mean (SD), was 8.4 (2.1) in the HPC-NL group and 11.8 (2.3) in the HPC-NL + B group
PMID:31344296 · one of two readings recorded this
Onychodystrophy Global Severity Score (OGSS) in brittle nail syndrome; proportion with OGSS reduction of at least 50%
53% with HPC-NL alone versus 80% with HPC-NL plus biotin had OGSS reduction of 50% or more, p = 0.05
Not recorded as a finding: this platform holds no node for the endpoint
At the end of study period, the percentage of subjects with an OGSS reduction of ≥50% in comparison with baseline was 53% in the HPC-NL group and 80% in the HPC-NL + B group (p = .05).
PMID:31344296 · one of two readings recorded this
Onychodystrophy Global Severity Score (OGSS) reduction of 50% or more in brittle nail syndrome
53% HPC-NL versus 80% HPC-NL + biotin with OGSS reduction of 50% or more, p = 0.05
Not recorded as a finding: this platform holds no node for the endpoint
At the end of study period, the percentage of subjects with an OGSS reduction of ≥50% in comparison with baseline was 53% in the HPC-NL group and 80% in the HPC-NL + B group (p = .05).
PMID:31344296 · one of two readings recorded this
subjects with OGSS reduction of ≥50% from baseline
increases, p = 0.05
the percentage of subjects with an OGSS reduction of ≥50% in comparison with baseline was 53% in the HPC-NL group and 80% in the HPC-NL + B group (p = .05)
PMID:31344296 · one of two readings recorded this
baseline EDSS
n = 178
At baseline, patients were 52.0 ± 9.4 years old, mean Expanded Disability Status Scale (EDSS) score was 6.1 ± 1.3, mean disease duration was 16.9 ± 9.5 years
PMID:31845825 · one of two readings recorded this
Expanded Disability Status Scale at 12 months after starting high-dose biotin in progressive multiple sclerosis, single-arm
3.8% of patients had an improved EDSS score
Not recorded as a finding: the result compares a group with itself, not with a control
At 12 months, 3.8% of the patients had an improved EDSS score.
PMID:31845825 · one of two readings recorded this
Expanded Disability Status Scale (EDSS) improvement at 12 months on high-dose biotin, single-arm prospective cohort with no control group
3.8% of patients had an improved EDSS score
Not recorded as a finding: the result compares a group with itself, not with a control
At 12 months, 3.8% of the patients had an improved EDSS score.
PMID:31845825 · one of two readings recorded this
patients describing improvement
In total, 47.4% of the patients described stability, 27.6% felt an improvement, and 25% described a worsening
PMID:31845825 · one of two readings recorded this
patients describing stability
In total, 47.4% of the patients described stability, 27.6% felt an improvement, and 25% described a worsening
PMID:31845825 · one of two readings recorded this
patients describing worsening
In total, 47.4% of the patients described stability, 27.6% felt an improvement, and 25% described a worsening
PMID:31845825 · one of two readings recorded this
patients with a relapse
n = 178
Four patients (2.2%) had a relapse
PMID:31845825 · one of two readings recorded this
patients with gadolinium-enhancing lesions on MRI
n = 74
Of the 74 patients (41.6%) who underwent an MRI, 20 (27.0%) had new T2 lesions, 8 (10.8%) had gadolinium-enhancing lesions
PMID:31845825 · one of two readings recorded this
patients with improved EDSS score
n = 178
At 12 months, 3.8% of the patients had an improved EDSS score
PMID:31845825 · one of two readings recorded this
patients with new T2 lesions on MRI
n = 74
Of the 74 patients (41.6%) who underwent an MRI, 20 (27.0%) had new T2 lesions, 8 (10.8%) had gadolinium-enhancing lesions
PMID:31845825 · one of two readings recorded this
cord blood serum biotin versus gestational age
increases
The levels of serum biotin in cord blood showed a significant positive correlation with gestational age
PMID:32378602 · one of two readings recorded this
maternal serum biotin across trimesters
no effect
Serum biotin concentrations of pregnant women remained low from first to third trimester
PMID:32378602 · one of two readings recorded this
maternal serum biotin, second and third trimester
decreases
The maternal serum biotin levels during second and third trimester of SGA group were significantly lower than those of normal term delivery
PMID:32378602 · one of two readings recorded this
maternal serum biotin versus gestational age
increases
that of pregnant women showed a weak positive correlation with gestational age
PMID:32378602 · one of two readings recorded this
number of relapses after versus before biotin initiation
increases, p = 0.0001, n = 42
incident rate ratio [IRR] 7.4, 95% confidence interval [CI] 3.5-15.9, p < 0.0001
PMID:32557122 · one of two readings recorded this
Sources cited
2 papers
- Subject
- biotin
- Findings
- 3
- Papers
- 2
High-dose biotin for multiple sclerosis: A systematic review and meta-analyses of randomized controlled trials.record2021PMID:343324612 findings
MD1003 (high-dose biotin) for the treatment of progressive multiple sclerosis: A randomised, double-blind, placebo-controlled study.record2016PMID:275890591 finding
Other names
2 names
Resolves to: biotin
- Also called
- biotin anion
- Systematic name
- 5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoate