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Proteins/UNIPROT:Q9UDR5
Bifunctional enzyme that catalyzes the first two steps in lysine degradation..
Function from UniProtKB (Q9UDR5), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
40 statements
40 statements · 8 reference databases · Subject: AASS · Sources: Bgee, gene ontology, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, WikiPathways
5 reactions
2-oxoglutarate(2-)+proton+CHEBI:18019+NADPH(4-)water+NADP(3-)+L-saccharopine
Catalysed by AASS
Reaction pageLeft to rightBalancedEC 1.5.1.8mitochondrial matrix
Human-GEM MAR04288CC BY 4.0Reference data
water+NAD(+)+L-saccharopineMAM00631m+L-glutamate(1-)
5 names
Resolves to: AASS
Reaction pageLeft to rightBalancedEC 1.5.1.9mitochondrial matrix
Human-GEM MAR04667CC BY 4.0Reference data
water+NADP(3-)+L-saccharopineMAM00631m+L-glutamate(1-)+proton+NADPH(4-)
Catalysed by AASS
Reaction pageLeft to rightBalancedEC 1.5.1.10mitochondrial matrix
Human-GEM MAR04668CC BY 4.0Reference data
L-saccharopine+NADP(3-)+waterL-lysine+2-oxoglutarate(2-)+NADPH(4-)+hydron
Catalysed by AASS
Reaction pageRight to leftBalanced
Rhea RHEA:19373CC BY 4.0Reference data
L-saccharopine+NAD(1-)+water(S)-2-amino-6-oxohexanoate+L-glutamate(1-)+NADH(2-)+hydron
Catalysed by AASS
Reaction pageLeft to rightBalanced
Rhea RHEA:24520CC BY 4.0Reference data