Compound
CHEBI:18183
A cyclized derivative of l-glutamic acid. Elevated blood levels may be associated with problems of glutamine or glutathione metabolism.
What it touches on the way
Mechanistic reach
2 entities
2 entities reached.
0 reported hops2 assembled from the scaffold
What the reference databases state
Statements
3 statements
3 statements · 1 reference database · Subject: CHEBI:18183 · Sources: Human-GEM
- CHEBI:18183 is a substrate of GGCTProteinHuman-GEM MAR06971Inferred only
- CHEBI:18183 is a substrate of GGCTProteinHuman-GEM MAR06972Inferred only
- CHEBI:18183 is a substrate of OPLAHProteinHuman-GEM MAR03889Inferred only
Reactions
10 reactions
CHEBI:18183+ATP+2waterADP+L-glutamate(1-)+proton+phosphate(3-)
Catalysed by OPLAH
Reaction pageLeft to rightBalancedEC 3.5.2.9cytosol
Human-GEM MAR03889CC BY 4.0Reference data
gamma-L-glutamyl-L-cysteineCHEBI:18183+L-cysteine
Reaction pageLeft to rightBalancedEC 4.3.2.9cytosol
Human-GEM MAR04708CC BY 4.0Reference data
L-alpha-aminobutyric acid+CHEBI:18183MAM01931c
Catalysed by GGCT
Reaction pageReversibleBalancedEC 4.3.2.9cytosol
Human-GEM MAR06971CC BY 4.0Reference data
CHEBI:18183+CHEBI:16856MAM01928c
Catalysed by GGCT
Reaction pageReversibleBalancedEC 4.3.2.9cytosol
Human-GEM MAR06972CC BY 4.0Reference data
gamma-Glu-AlaCHEBI:18183+L-alanine
Reaction pageLeft to rightBalancedEC 4.3.2.9extracellular space, cytosol
Human-GEM MAR08770CC BY 4.0Reference data
CHEBI:18183+2sodium(1+)CHEBI:18183+2sodium(1+)
Reaction pageReversibleBalancedextracellular space, cytosol
Human-GEM MAR09005CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR09025CC BY 4.0Reference data
water+MAM03040cCHEBI:18183+MAM02126c
Catalysed by TRHDE
Reaction pageLeft to rightBalancedEC 3.4.19.6cytosol
Human-GEM MAR09476CC BY 4.0Reference data
epsilon-(gamma-L-glutamyl)-L-lysineCHEBI:18183+CHEBI:18019
Catalysed by GGACT
Reaction pageLeft to rightBalancedEC 4.3.2.8cytosol
Human-GEM MAR20071CC BY 4.0Reference data
epsilon-(gamma-L-glutamyl)-L-lysineCHEBI:18183+CHEBI:18019
Catalysed by GGACT
Reaction pageLeft to rightBalancedEC 4.3.2.8nucleus
Human-GEM MAR20072CC BY 4.0Reference data
On the label
Labelled products
32 products
Source: NIH DSLD · Ingredient: CHEBI:18183 · 32 products · Declared amount per serving: 50–1,000 mg (30 products)
31 labels state an amount1 does not
- BluebonnetPower Thought125 mgper 2 Caplet(s)DSLD:179161
- BluebonnetPower Thought125 mgper 2 Caplet(s)DSLD:179176
- BluebonnetPower Thought125 mgper 2 Caplet(s)DSLD:179183
- BulkSupplements.comL-Pyroglutamic Acid1,000 mgper 1000 mgDSLD:252821
- BulkSupplements.comL-Pyroglutamic Acid1,000 mgper 1000 mgDSLD:254743
- BulkSupplements.comL-Pyroglutamic Acid1,000 mgper 1000 mgDSLD:254744
- BulkSupplements.comL-Pyroglutamic Acid1,000 mgper 1000 mgDSLD:254745
- BulkSupplements.comL-Pyroglutamic Acid1,000 mgper 1000 mgDSLD:312264
- BulkSupplements.comL-Pyroglutamic Acid1,000 mgper 1000 mgDSLD:312265
- BulkSupplements.comL-Pyroglutamic Acid1,000 mgper 1000 mgDSLD:312266
- BulkSupplements.comL-Pyroglutamic Acid1,000 mgper 1000 mgDSLD:312267
- Buried Treasure Liquid NutrientsNeuro Nectar200 mgper 30 mLDSLD:250726
Show the remaining 20
- Douglas LaboratoriesNeuroTone250 mgper 4 Tablet(s)DSLD:261489
- Drucker LabsintraMAX 2.0 Peach Mango Flavoramount not statedper 1 fl. Oz.DSLD:236722
- H!D Hallelujah DietBrain Health Support100 mgper 2 Tablet(s)DSLD:240434
- Integrative TherapeuticsVitaline Neuro-Essentials125 mgper 2 Caplet(s)DSLD:24221
- Nootropics DepotL-Pyroglutamic Acid Capsules 500 mg1,000 mgper 2 Capsule(s)DSLD:285716
- Nootropics DepotL-Pyroglutamic Acid Powder1,000 mgper 1000 mgDSLD:285717
- Source NaturalsAgeless Mind100 mgper 1 Tablet(s)DSLD:181668
- Source NaturalsAgeless Mind100 mgper 1 Tablet(s)DSLD:181678
- Source NaturalsAgeless Mind100 mgper 1 Tablet(s)DSLD:181686
- Source NaturalsHigher Mind600 mgper 1 Tablet(s)DSLD:274666
- Source NaturalsHigher Mind With Phosphatidylserine600 mgper 4 Tablet(s)DSLD:75377
- Source NaturalsMegaMind1 Gram(s)per 1 Tablet(s)DSLD:296055
- Source NaturalsMental Edge500 mgper 4 Tablet(s)DSLD:296084
- Source NaturalsMental Edge500 mgper 4 Tablet(s)DSLD:80973
- SuperSmartNeuro Nutrition Formula100 mgper 1 Capsule(s)DSLD:332470
- Whole FoodsThink Smart with Gingko Biloba100 mgper 1 Capsule(s)DSLD:12093
- Whole Foods MarketThinkSmart100 mgper 1 Capsule(s)DSLD:308942
- XtendlifeTotal Balance Men's Premium50 mgper 7 Tablet(s)DSLD:331309
- XtendlifeTotal Balance Unisex Premium50 mgper 6 Tablet(s)DSLD:283408
- XtendlifeTotal Balance Women's Premium50 mgper 7 Tablet(s)DSLD:331312
Label record: NIH Office of Dietary Supplements · CC0
Other names
13 names
Resolves to: CHEBI:18183
- Also called
- (-)-2-pyrrolidone-5-carboxylic acid(−)-2-pyrrolidone-5-carboxylic acid(S)-(-)-2-pyrrolidone-5-carboxylic acid(S)-(−)-2-pyrrolidone-5-carboxylic acid(S)-pyroglutamic acid5-Oxo-L-proline5-Pyrrolidone-2-carboxylic acidL-5-Pyrrolidone-2-carboxylic acidL-Pyroglutamic acidpidolic acidPyroglutamatePYROGLUTAMIC ACID
- Systematic name
- (2S)-5-oxopyrrolidine-2-carboxylic acid