Compound
D-ribose 5-phosphate
An organophosphate oxoanion obtained by deprotonation of the phosphate OH groups of D-ribofuranose-5-phosphate; major species at pH 7.3.
Definition from ChEBI (CHEBI:78346), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Organic compound, anion
- Formula
- C5H9O8P
- Mass
- 228.093 g/mol
- Charge
- -2
- InChIKey
- KTVPXOYAKDPRHY-SOOFDHNKSA-L
- SMILES
- O=P([O-])([O-])OC[C@H]1OC(O)[C@H](O)[C@@H]1O
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
7 entities
7 entities reached.
0 reported hops7 assembled from the scaffold
- PRPS1ProteinUNIPROT:P60891substrate ofInferred only15 paths15 endpoints
- PGM2ProteinUNIPROT:Q96G03substrate ofInferred only9 paths9 endpoints
- NUDT5ProteinUNIPROT:Q9UKK9substrate ofInferred only8 paths8 endpoints
- PRPS2ProteinUNIPROT:P11908substrate ofInferred only7 paths7 endpoints
- CRPPAProteinUNIPROT:A4D126substrate ofInferred only5 paths5 endpoints
- PRPS1L1ProteinUNIPROT:P21108substrate ofInferred only5 paths5 endpoints
- RBKSProteinUNIPROT:Q9H477substrate ofInferred only4 paths4 endpoints
What the reference databases state
Statements
27 statements
27 statements · 1 reference database · Subject: D-ribose 5-phosphate · Sources: Rhea
- D-ribose 5-phosphate is converted to 5-phospho-alpha-D-ribose 1-diphosphateCompoundRhea RHEA:15609Inferred only
- 5-phospho-beta-D-ribosylamine is converted to D-ribose 5-phosphateCompoundRhea RHEA:13777Inferred only
- D-ribose 5-phosphate is converted to 5-phospho-beta-D-ribosylamineCompoundRhea RHEA:13777Inferred only
- D-ribose 5-phosphate is converted to ADP-D-riboseCompoundRhea RHEA:50248Inferred only
- D-ribose 5-phosphate is converted to ADP-D-riboseCompoundRhea RHEA:14529Inferred only
- ADP-D-ribose is converted to D-ribose 5-phosphateCompoundRhea RHEA:10412Inferred only
- ADP-D-ribose is converted to D-ribose 5-phosphateCompoundRhea RHEA:14529Inferred only
- ADP-D-ribose is converted to D-ribose 5-phosphateCompoundRhea RHEA:50248Inferred only
- aldehydo-D-ribose 5-phosphate is converted to D-ribose 5-phosphateCompoundRhea RHEA:54528Inferred only
- D-ribose 5-phosphate is converted to aldehydo-D-ribose 5-phosphateCompoundRhea RHEA:54528Inferred only
- D-ribose 5-phosphate is converted to alpha-D-ribose 1-phosphateCompoundRhea RHEA:18793Inferred only
- alpha-D-ribose 1-phosphate is converted to D-ribose 5-phosphateCompoundRhea RHEA:18793Inferred only
Show the remaining 15
- D-ribose 5-phosphate is converted to alpha-D-ribose 1,5-bisphosphateCompoundRhea RHEA:21216Inferred only
- alpha-D-ribose 1,5-bisphosphate is converted to D-ribose 5-phosphateCompoundRhea RHEA:21216Inferred only
- CDP-D-ribose is converted to D-ribose 5-phosphateCompoundRhea RHEA:53872Inferred only
- D-ribose 5-phosphate is converted to CDP-D-riboseCompoundRhea RHEA:53872Inferred only
- D-ribose is converted to D-ribose 5-phosphateCompoundRhea RHEA:13697Inferred only
- D-ribose is converted to D-ribose 5-phosphateCompoundRhea RHEA:29471Inferred only
- D-ribose 5-phosphate is converted to D-riboseCompoundRhea RHEA:29471Inferred only
- D-ribose 5-phosphate is converted to D-riboseCompoundRhea RHEA:13697Inferred only
- D-ribose 5-phosphate is a substrate of CRPPAProteinRhea RHEA:53872Inferred only
- D-ribose 5-phosphate is a substrate of NUDT5ProteinRhea RHEA:50248Inferred only
- D-ribose 5-phosphate is a substrate of PGM2ProteinRhea RHEA:18793Inferred only
- D-ribose 5-phosphate is a substrate of PRPS1ProteinRhea RHEA:15609Inferred only
- D-ribose 5-phosphate is a substrate of PRPS1L1ProteinRhea RHEA:15609Inferred only
- D-ribose 5-phosphate is a substrate of PRPS2ProteinRhea RHEA:15609Inferred only
- D-ribose 5-phosphate is a substrate of RBKSProteinRhea RHEA:13697Inferred only
Reactions
25 reactions
ADP-D-ribose+waterD-ribose 5-phosphate+AMP+2hydron
Catalysed by NUDT14 or ADPRM or NUDT9 or NUDT5
Reaction pageLeft to rightBalanced
Rhea RHEA:10412CC BY 4.0Reference data
CHEBI:138238+waterCHEBI:26432+D-ribose 5-phosphate
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:13425CC BY 4.0Reference data
D-ribose+ATP(4-)D-ribose 5-phosphate+ADP(3-)+hydron
Catalysed by RBKS
Reaction pageDirection not assertedBalanced
Rhea RHEA:13697CC BY 4.0Reference data
D-ribose 5-phosphate+ammonium+ATP(4-)5-phospho-beta-D-ribosylamine+ADP(3-)+hydrogenphosphate+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:13777CC BY 4.0Reference data
D-ribose 5-phosphate+ADP(3-)+hydronADP-D-ribose+hydrogenphosphate
Reaction pageDirection not assertedBalanced
Rhea RHEA:14529CC BY 4.0Reference data
D-ribose 5-phosphate+ATP(4-)5-phospho-alpha-D-ribose 1-diphosphate+AMP+hydron
Catalysed by PRPS2 or PRPS1L1 or PRPS1
Reaction pageLeft to rightBalanced
Rhea RHEA:15609CC BY 4.0Reference data
D-ribose 5-phosphate+uracilCHEBI:58380+water
Reaction pageDirection not assertedBalanced
Rhea RHEA:18337CC BY 4.0Reference data
alpha-D-ribose 1-phosphateD-ribose 5-phosphate
Catalysed by PGM2
Reaction pageDirection not assertedBalanced
Rhea RHEA:18793CC BY 4.0Reference data
AMP+waterD-ribose 5-phosphate+adenine
Reaction pageDirection not assertedBalanced
Rhea RHEA:20129CC BY 4.0Reference data
IMP+waterhypoxanthine+D-ribose 5-phosphate
Reaction pageDirection not assertedBalanced
Rhea RHEA:20469CC BY 4.0Reference data
D-ribose 5-phosphate+ATP(4-)alpha-D-ribose 1,5-bisphosphate+ADP(3-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:21216CC BY 4.0Reference data
NMN zwitterion+waterD-ribose 5-phosphate+nicotinamide+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:23140CC BY 4.0Reference data
Other names
1 name
Resolves to: D-ribose 5-phosphate
- Systematic name
- 5-O-phosphonato-D-ribofuranose