CHEBI:15727

Two steps

• CHEBI:27540Reach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. medium-chain acyl-CoA ligase (hexanoic acid)

  Catalysed by NAA10, ACSM4, ACSM1, ACSM2A and 3 morecytosolOne of 6 routes

• elaidic acidReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. long-chain-fatty-acid-CoA ligase (elaidate)

  Catalysed by NAA10, SLC27A2, ACSL4, ACSL3 and 5 morecytosolOne of 5 routes

• CHEBI:28701Reach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. Propanoyl-CoA:acetyl-CoA C-acyltransferase

  Catalysed by NAA10, ACAA1, SCP2, MYO5Bcytosol, peroxisomeOne of 7 routes

• chlorine(.)Reach from here →
  1. Nalpha-(beta-alanyl)-L-histidine hydrolase
  2. transport of beta-alanine and chloride (cytosol to extracellular)

  Catalysed by CNDP1, CNDP2, SLC6A6, SLC6A14cytosol, extracellular spaceOne of 3 routes

• L-aspartateReach from here →
  1. Nalpha-(beta-alanyl)-L-histidine hydrolase
  2. L-aspartate + H(+) = beta-alanine + CO2

  Catalysed by CNDP1, CNDP2, GADL1, CSADcytosol

• 3-oxopropanoateReach from here →
  1. Nalpha-(beta-alanyl)-L-histidine hydrolase
  2. 3-oxopropanoate + L-alanine = beta-alanine + pyruvate

  Catalysed by CNDP1, CNDP2, AGXT2cytosol

• L-ornithineReach from here →
  1. Nalpha-(beta-alanyl)-L-histidine hydrolase
  2. beta-alanine + L-arginine = 3-guanidinopropanoate + L-ornithine

  Catalysed by CNDP1, CNDP2, GATMcytosolOne of 5 routes

• taurineReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. bile acid-CoA:amino acid N-acyltransferase (taurodeoxycholate)

  Catalysed by NAA10, BAATcytosolOne of 2 routes

• glycineReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. glycine N-acyltransferase (N-arachidonoylglycine)

  Catalysed by NAA10, GLYAT, GLYATL2, GLYATL1cytosol, mitochondrial matrixOne of 12 routes

• (R)-methylmalonyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. aldehyde dehydrogenase (2-methyl-3-oxopropanoate)

  Catalysed by NAA10, ALDH6A1cytosol, mitochondrial matrixOne of 2 routes

• (S)-methylmalonyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. (S)-methylmalonyl-CoA hydrolase

  Catalysed by NAA10cytosol, mitochondrial matrix

• 3'-dephospho-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. acid phosphatase 2, lysosomal (CoA)

  Catalysed by NAA10, ACP2cytosol, lysosomeOne of 2 routes

• (2E)-dodecenoyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. (2E)-dodecenoyl-CoA formation

  Catalysed by NAA10cytosol, mitochondrial matrixOne of 3 routes

• 4,8,12-trimethyltridecanoyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. propanoyl-CoA C-acyltransferase (3-ketopristanoyl-CoA)

  Catalysed by NAA10, ACAA1, MYO5Bcytosol, peroxisomeOne of 2 routes

• (6Z,9Z,12Z)-octadecatrienoyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. long-chain-fatty-acid-CoA ligase (gamma-linolenate)

  Catalysed by NAA10, SLC27A2, ACSL4, ACSL3 and 5 morecytosolOne of 7 routes

• butanoyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. Butanoate:CoA ligase (AMP-forming)

  Catalysed by NAA10, ACSM4, ACSM1, ACSM2A and 3 morecytosolOne of 9 routes

• dodecanoyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. long-chain-fatty-acid-CoA ligase (lauric acid)

  Catalysed by NAA10, SLC27A2, ACSL4, ACSL3 and 5 morecytosolOne of 9 routes

• glutaryl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. Production of Glutaryl Carnitine

  Catalysed by NAA10, CPT1A, CPT1C, CPT1BcytosolOne of 2 routes

• eicosanoyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. long-chain-fatty-acid-CoA ligase (eicosanoate)

  Catalysed by NAA10, SLC27A2, ACSL4, ACSL3 and 5 morecytosolOne of 12 routes

• itaconyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. Itaconate:CoA ligase (GDP-forming)

  Catalysed by NAA10, SUCLG1, SUCLG2, SUCLA2cytosol, mitochondrial matrixOne of 2 routes

• (9Z,12Z)-octadecadienoyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)

  Catalysed by NAA10, SLC27A2, ACSL4, ACSL3 and 5 morecytosolOne of 13 routes

• tetradecanoyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. long-chain-fatty-acid-CoA ligase (myristic acid)

  Catalysed by NAA10, SLC27A2, ACSL4, ACSL3 and 5 morecytosolOne of 11 routes

• octanoyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. Octanoyl-CoA:L-carnitine O-octanoyltransferase

  Catalysed by NAA10, CROTcytosol, mitochondrial matrixOne of 20 routes

• phytanoyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. phytanate-CoA ligase

  Catalysed by NAA10cytosolOne of 5 routes

• octadecanoyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. long-chain-fatty-acid-CoA ligase (stearate)

  Catalysed by NAA10, SLC27A2, ACSL4, ACSL3 and 4 morecytosolOne of 15 routes

• carnosineReach from here →
  1. Nalpha-(beta-alanyl)-L-histidine hydrolase
  2. beta-alanine + L-histidine + ATP = carnosine + ADP + phosphate + H(+)

  Catalysed by CNDP1, CNDP2, CARNS1cytosol

• 3-guanidinopropanoateReach from here →
  1. Nalpha-(beta-alanyl)-L-histidine hydrolase
  2. beta-alanine + L-arginine = 3-guanidinopropanoate + L-ornithine

  Catalysed by CNDP1, CNDP2, GATMcytosol

• sphing-4-enineReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. acyl-CoA:sphingosine N-acyltransferase

  Catalysed by NAA10, ASAH1, ACER2, ACER1 and 1 morecytosol, Golgi apparatusOne of 2 routes

• spermidineReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. diamine N-acetyltransferase (N1-acetylspermidine)

  Catalysed by NAA10, SAT1, SAT2cytosolOne of 3 routes

• L-methionineReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. N-acetylglutamate synthase (N-acetylmethionine)

  Catalysed by NAA10, NAGScytosol, mitochondrial matrixOne of 3 routes

• L-tryptophanReach from here →
  1. Nalpha-(beta-alanyl)-L-histidine hydrolase
  2. transport of histidine and tryptophan (cytosol to extracellular)

  Catalysed by CNDP1, CNDP2, SLC7A6cytosol, extracellular spaceOne of 2 routes

• L-alanineReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. amino-acid N-acetyltransferase (N-acetyl-L-alanine)

  Catalysed by NAA10cytosol, mitochondrial matrixOne of 6 routes

• L-asparagineReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. N-acetylglutamate synthase (N-acetyl-L-asparagine)

  Catalysed by NAA10, NAGScytosol, mitochondrial matrixOne of 3 routes

• L-phenylalanineReach from here →
  1. Nalpha-(beta-alanyl)-L-histidine hydrolase
  2. transport of histidine and phenylalanine (cytosol to extracellular)

  Catalysed by CNDP1, CNDP2, SLC7A6cytosol, extracellular spaceOne of 2 routes

• L,L-cystathionineReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. N-acetylglutamate synthase (N-acetyl-L-cystathionine)

  Catalysed by NAA10, NAGScytosol, mitochondrial matrix

• an acyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. acyl-CoA:sphingosine N-acyltransferase

  Catalysed by NAA10, ASAH1, ACER2, ACER1 and 1 morecytosol, Golgi apparatusOne of 2 routes

• histamineReach from here →
  1. Nalpha-(beta-alanyl)-L-histidine hydrolase
  2. L-histidine carboxy-lyase (histamine-forming)

  Catalysed by CNDP1, CNDP2, HDCcytosol

• (3Z)-dodecenoyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. acetyl-CoA C-acyltransferase (3-oxomyrist-5-enoyl-CoA)

  Catalysed by NAA10, HADHA, ACAA2, HADHBcytosol, mitochondrial matrixOne of 3 routes

• (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate:CoA ligase (AMP-forming)

  Catalysed by NAA10, SLC27A2, SLC27A5cytosol, endoplasmic reticulumOne of 3 routes

• deoxycholoyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. cholate-CoA ligase (3alpha,12alpha-dihydroxy-5beta-cholanate)

  Catalysed by NAA10, SLC27A2, SLC27A5cytosolOne of 4 routes

• decanoyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. medium-chain acyl-CoA ligase (decanoic acid)

  Catalysed by NAA10, ACSM4, ACSM1, ACSM2A and 3 morecytosolOne of 7 routes

• (2E)-hexadecenoyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. Carnitine O-Palmitoyltransferase

  Catalysed by NAA10, CPT1A, CPT1C, CPT1BcytosolOne of 4 routes

• (9Z)-hexadecenoyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. long-chain-fatty-acid-CoA ligase (palmitolate)

  Catalysed by NAA10, SLC27A2, ACSL4, ACSL3 and 5 morecytosolOne of 11 routes

• 3-hydroxyisovaleryl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. (3-Hydroxyisovalerylcoa->3-Hydroxyisovalerylcarnitine)

  Catalysed by NAA10, CPT1A, CPT1Bcytosol

• CHEBI:63544Reach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. long-chain-fatty-acid-CoA ligase (adrenic acid)

  Catalysed by NAA10, SLC27A2, ACSL4, ACSL3 and 5 morecytosolOne of 7 routes

• hexacosanoyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. long-chain-fatty-acid-CoA ligase (cerotic acid)

  Catalysed by NAA10, SLC27A2, ACSL4, ACSL3 and 5 morecytosolOne of 5 routes

• tetracosanoyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. long-chain-fatty-acid-CoA ligase (lignocerate)

  Catalysed by NAA10, SLC27A2, ACSL4, ACSL3 and 5 morecytosolOne of 10 routes

• docosanoyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. long-chain-fatty-acid-CoA ligase (behenic acid)

  Catalysed by NAA10, SLC27A2, ACSL4, ACSL3 and 5 morecytosolOne of 9 routes

• (2E)-octadecenoyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. Carnitine O-Palmitoyltransferase

  Catalysed by NAA10, CPT1A, CPT1C, CPT1BcytosolOne of 3 routes

• (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoAReach from here →
  1. N-alpha-acetyltransferase 10, NatA catalytic subunit (acetylcarnosine)
  2. long-chain-fatty-acid-CoA ligase (stearidonic acid)

  Catalysed by NAA10, SLC27A2, ACSL4, ACSL3 and 5 morecytosolOne of 8 routes